GB0800272D0 - Protein expression systems - Google Patents

Protein expression systems

Info

Publication number
GB0800272D0
GB0800272D0 GBGB0800272.7A GB0800272A GB0800272D0 GB 0800272 D0 GB0800272 D0 GB 0800272D0 GB 0800272 A GB0800272 A GB 0800272A GB 0800272 D0 GB0800272 D0 GB 0800272D0
Authority
GB
United Kingdom
Prior art keywords
protein expression
expression systems
systems
protein
expression
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB0800272.7A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Plant Bioscience Ltd
Original Assignee
Plant Bioscience Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Plant Bioscience Ltd filed Critical Plant Bioscience Ltd
Priority to GBGB0800272.7A priority Critical patent/GB0800272D0/en
Publication of GB0800272D0 publication Critical patent/GB0800272D0/en
Priority to JP2010541103A priority patent/JP5745857B2/ja
Priority to BRPI0906509A priority patent/BRPI0906509A2/pt
Priority to CN200980105869.XA priority patent/CN101952446B/zh
Priority to DK09700649T priority patent/DK2240589T3/en
Priority to EP09700649.8A priority patent/EP2240589B1/en
Priority to KR1020107017609A priority patent/KR101602972B1/ko
Priority to NZ586939A priority patent/NZ586939A/xx
Priority to AU2009203608A priority patent/AU2009203608B2/en
Priority to PT97006498T priority patent/PT2240589E/pt
Priority to MX2010007336A priority patent/MX2010007336A/es
Priority to PCT/GB2009/000060 priority patent/WO2009087391A1/en
Priority to ES09700649.8T priority patent/ES2537198T3/es
Priority to CA2711895A priority patent/CA2711895C/en
Priority to RU2010133217/10A priority patent/RU2539793C2/ru
Priority to US12/812,165 priority patent/US8674084B2/en
Priority to IL206606A priority patent/IL206606A/en
Priority to ZA2010/05245A priority patent/ZA201005245B/en
Priority to US14/172,301 priority patent/US20140250549A1/en
Priority to US15/674,881 priority patent/US10822613B2/en
Priority to US17/007,242 priority patent/US10947549B2/en
Priority to US17/016,191 priority patent/US20210155947A1/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/08—RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
    • C12N15/8202—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation by biological means, e.g. cell mediated or natural vector
    • C12N15/8203—Virus mediated transformation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • C12N15/8258—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon for the production of oral vaccines (antigens) or immunoglobulins

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
GBGB0800272.7A 2008-01-08 2008-01-08 Protein expression systems Ceased GB0800272D0 (en)

Priority Applications (22)

Application Number Priority Date Filing Date Title
GBGB0800272.7A GB0800272D0 (en) 2008-01-08 2008-01-08 Protein expression systems
US12/812,165 US8674084B2 (en) 2008-01-08 2009-01-08 Protein expression system
MX2010007336A MX2010007336A (es) 2008-01-08 2009-01-08 Sistemas de expresion de proteina.
ES09700649.8T ES2537198T3 (es) 2008-01-08 2009-01-08 Sistemas de expresión de proteínas
CN200980105869.XA CN101952446B (zh) 2008-01-08 2009-01-08 蛋白表达系统
DK09700649T DK2240589T3 (en) 2008-01-08 2009-01-08 Protein Expression Systems
EP09700649.8A EP2240589B1 (en) 2008-01-08 2009-01-08 Protein expression systems
KR1020107017609A KR101602972B1 (ko) 2008-01-08 2009-01-08 단백질 발현 시스템
NZ586939A NZ586939A (en) 2008-01-08 2009-01-08 Cpmv rna-2 genome segment derived protein expression systems
AU2009203608A AU2009203608B2 (en) 2008-01-08 2009-01-08 Protein expression systems
PT97006498T PT2240589E (pt) 2008-01-08 2009-01-08 Sistemas de expressão de proteínas
JP2010541103A JP5745857B2 (ja) 2008-01-08 2009-01-08 タンパク質発現系
PCT/GB2009/000060 WO2009087391A1 (en) 2008-01-08 2009-01-08 Protein expression systems
BRPI0906509A BRPI0906509A2 (pt) 2008-01-08 2009-01-08 constructo de expressão de gene, sistema de expressão de gene, varaiação de um sistema de expressão de gene, processo para aumentar a expressão ou melhorar a atividade translacional de uma sequência derivada de um segmento do genoma de rna-2 de um vírus bipartido, métodos para expressar uma proteína de interesse em um organismo hospedeiro, para melhorar a tradução de uma proteína de interesse heteróloga de um gene ou quadro de leitura aberto, para expressar uma proteína constructo de expressão de gene , sistema de expressão de gene, variação de um sistema de expressão de gene, processo para aumentar a expressão ou melhorar a atividade translacional de uma sequência derivada de um segmento do genoma de rna -2 de um vírus bipartido, métodos para expressar um a proteína de interesse em um organismo hospedeiro, para melhorar a tradução de uma proteína de interesse heteróloga de um gene ou quadro de leitura aberto, para expressar uma proteína em uma planta e para gerar um proteína de interesse, e, organismo hospedeiro
CA2711895A CA2711895C (en) 2008-01-08 2009-01-08 Methods for protein production employing expression enhancer sequences derived from the rna-z segment of a comoviridae bipartite rna virus
RU2010133217/10A RU2539793C2 (ru) 2008-01-08 2009-01-08 Системы экспрессии белка
IL206606A IL206606A (en) 2008-01-08 2010-06-24 Gene expression systems and methods for their use
ZA2010/05245A ZA201005245B (en) 2008-01-08 2010-07-22 Protein expression systems
US14/172,301 US20140250549A1 (en) 2008-01-08 2014-02-04 Protein expression systems
US15/674,881 US10822613B2 (en) 2008-01-08 2017-08-11 Protein expression systems
US17/007,242 US10947549B2 (en) 2008-01-08 2020-08-31 Protein expression systems
US17/016,191 US20210155947A1 (en) 2008-01-08 2020-09-09 Protein expression systems

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0800272.7A GB0800272D0 (en) 2008-01-08 2008-01-08 Protein expression systems

Publications (1)

Publication Number Publication Date
GB0800272D0 true GB0800272D0 (en) 2008-02-13

Family

ID=39111256

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB0800272.7A Ceased GB0800272D0 (en) 2008-01-08 2008-01-08 Protein expression systems

Country Status (18)

Country Link
US (5) US8674084B2 (https=)
EP (1) EP2240589B1 (https=)
JP (1) JP5745857B2 (https=)
KR (1) KR101602972B1 (https=)
CN (1) CN101952446B (https=)
AU (1) AU2009203608B2 (https=)
BR (1) BRPI0906509A2 (https=)
CA (1) CA2711895C (https=)
DK (1) DK2240589T3 (https=)
ES (1) ES2537198T3 (https=)
GB (1) GB0800272D0 (https=)
IL (1) IL206606A (https=)
MX (1) MX2010007336A (https=)
NZ (1) NZ586939A (https=)
PT (1) PT2240589E (https=)
RU (1) RU2539793C2 (https=)
WO (1) WO2009087391A1 (https=)
ZA (1) ZA201005245B (https=)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2615372A1 (en) 2007-07-13 2009-01-13 Marc-Andre D'aoust Influenza virus-like particles (vlps) comprising hemagglutinin
WO2009076778A1 (en) 2007-11-27 2009-06-25 Medicago Inc. Recombinant influenza virus-like particles (vlps) produced in transgenic plants expressing hemagglutinin
GB0800272D0 (en) 2008-01-08 2008-02-13 Plant Bioscience Ltd Protein expression systems
AU2009267769B2 (en) 2008-07-08 2015-07-16 Medicago Inc. Soluble recombinant influenza antigens
HUE039100T2 (hu) 2009-06-24 2018-12-28 Medicago Inc Hemagglutinint tartalmazó kimer influenzavírus-jellegû részecskék
GB201002434D0 (en) * 2010-02-12 2010-03-31 Plant Bioscience Ltd Non-infectious RNA source
WO2012058762A1 (en) 2010-11-04 2012-05-10 Medicago Inc. Plant expression system
PT2665818T (pt) 2011-01-17 2017-07-05 Philip Morris Products Sa Expressão de proteínas em plantas
CA2824155A1 (en) 2011-01-17 2012-07-26 Philip Morris Products S.A. Vectors for nucleic acid expression in plants
US11390878B2 (en) 2011-09-30 2022-07-19 Medicago Inc. Increasing protein yield in plants
NZ622731A (en) 2011-09-30 2016-04-29 Medicago Inc Increasing virus-like particle yield in plants
BR112014011345A2 (pt) * 2011-11-11 2017-05-16 Philip Morris Products Sa partículas tipo vírus da influenza (vlps) compreendendo nicotiana tabacum produzida por hemaglutinina
JP2015528285A (ja) * 2012-09-05 2015-09-28 メディカゴ インコーポレイテッド 植物におけるピコルナウイルス様粒子の産生
KR101449155B1 (ko) * 2012-12-06 2014-10-13 주식회사 바이오앱 식물체에서 목적 단백질의 번역 효율을 증진시키기 위한 염기서열
US12467058B2 (en) 2013-03-28 2025-11-11 Aramis Biotechnologies Inc. Influenza virus-like particle production in plants
ES2803508T3 (es) 2013-03-28 2021-01-27 Medicago Inc Producción de partículas similares al virus de la gripe en plantas
RU2699982C2 (ru) * 2014-01-10 2019-09-11 Медикаго Инк. Энхансерные элементы cpmv
US10563213B2 (en) 2014-03-27 2020-02-18 Medicago Inc. Modified CPMV enhancer elements
RU2731295C2 (ru) 2014-07-11 2020-09-01 Медикаго Инк. Модификация продуцирования белков в растениях
AU2016208999A1 (en) 2015-01-23 2017-07-13 Medicago Inc. Rotavirus-like particle production in plants
JP2018524345A (ja) 2015-07-02 2018-08-30 メディカゴ インコーポレイテッド ジャスモン酸経路アクチベーター
CN110506118A (zh) * 2017-02-02 2019-11-26 杜克大学 用于控制基因表达的组合物和方法
GB201721600D0 (en) 2017-12-21 2018-02-07 Plant Bioscience Ltd Metabolic engineering
CN112400021A (zh) 2018-03-14 2021-02-23 麦迪卡格公司 植物表达增强子
GB201808617D0 (en) 2018-05-25 2018-07-11 Plant Bioscience Ltd Scaffold modification
WO2020033416A1 (en) * 2018-08-06 2020-02-13 Northwestern University Combined transcription and translation platform derived from plant chloroplasts
WO2020181354A1 (en) 2019-03-14 2020-09-17 Mitsubishi Tanabe Pharma Corporation Endogenous plant expression enhancer
GB201908431D0 (en) 2019-06-12 2019-07-24 Plant Bioscience Ltd Biosynthetic genes and polypeptides
CN114040979B (zh) * 2019-06-21 2024-06-28 国立大学法人大阪大学 稳定地保持外源基因的人工重组rna病毒的制作方法
GB201909104D0 (en) 2019-06-25 2019-08-07 Plant Bioscience Ltd Transferase enzymes
CN110468129B (zh) * 2019-08-08 2023-03-24 四川农业大学 一种基于cmv rna2的体外干扰黄瓜花叶病的制剂、其制备方法与应用
CN111777670B (zh) * 2020-06-19 2021-07-30 东北农业大学 一种pH调节自组装抗菌肽及制备方法和应用
WO2022260849A1 (en) 2021-06-09 2022-12-15 Nant Holdings Ip, Llc Methods and systems for producing a protein of interest in a plant
CN114181969B (zh) * 2021-12-09 2024-05-28 苏州大学 一种制备包裹外源蛋白的多角体的方法
GB202209501D0 (en) 2022-06-29 2022-08-10 Plant Bioscience Ltd Biosynthetic enzymes
CN121195070A (zh) 2023-04-03 2025-12-23 斯威夫特制药有限责任公司 用于在植物中高效异源基因表达的反式互补载体系统
KR20250082120A (ko) * 2023-11-29 2025-06-09 서강대학교산학협력단 검은눈콩 모자이크 바이러스의 바이러스 유사 입자의 제조방법 및 이의 활용

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DE19701141C1 (de) * 1997-01-16 1998-04-09 Hoechst Ag Genkonstrukte für durch Proteasen aktivierbare Wirksubstanzen
AU7373801A (en) * 2000-06-13 2001-12-24 Univ Queensland Expression modulating sequences
CA2651907C (en) * 2006-05-22 2016-12-20 Plant Bioscience Limited Bipartite system, method and composition for the constitutive and inducible expression of high levels of foreign proteins in plants
GB0800272D0 (en) 2008-01-08 2008-02-13 Plant Bioscience Ltd Protein expression systems
RU2699982C2 (ru) 2014-01-10 2019-09-11 Медикаго Инк. Энхансерные элементы cpmv
US10563213B2 (en) 2014-03-27 2020-02-18 Medicago Inc. Modified CPMV enhancer elements

Also Published As

Publication number Publication date
US20140250549A1 (en) 2014-09-04
US20200392522A1 (en) 2020-12-17
KR101602972B1 (ko) 2016-03-11
EP2240589B1 (en) 2015-03-04
MX2010007336A (es) 2010-08-16
CA2711895C (en) 2016-08-09
EP2240589A1 (en) 2010-10-20
RU2010133217A (ru) 2012-02-20
IL206606A (en) 2015-11-30
ES2537198T3 (es) 2015-06-03
BRPI0906509A2 (pt) 2015-12-01
CN101952446B (zh) 2014-06-11
AU2009203608A1 (en) 2009-07-16
CN101952446A (zh) 2011-01-19
US8674084B2 (en) 2014-03-18
JP5745857B2 (ja) 2015-07-08
JP2011509081A (ja) 2011-03-24
DK2240589T3 (en) 2015-05-04
US10822613B2 (en) 2020-11-03
IL206606A0 (en) 2010-12-30
AU2009203608B2 (en) 2014-03-27
KR20100109950A (ko) 2010-10-11
CA2711895A1 (en) 2009-07-16
US20210155947A1 (en) 2021-05-27
US10947549B2 (en) 2021-03-16
PT2240589E (pt) 2015-06-18
US20180030462A1 (en) 2018-02-01
NZ586939A (en) 2012-08-31
US20100287670A1 (en) 2010-11-11
ZA201005245B (en) 2012-01-25
RU2539793C2 (ru) 2015-01-27
WO2009087391A1 (en) 2009-07-16

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)