NZ582876A - Tailored multi-site combinatorial assembly of polynucleotides - Google Patents
Tailored multi-site combinatorial assembly of polynucleotides Download PDFInfo
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- NZ582876A NZ582876A NZ582876A NZ58287608A NZ582876A NZ 582876 A NZ582876 A NZ 582876A NZ 582876 A NZ582876 A NZ 582876A NZ 58287608 A NZ58287608 A NZ 58287608A NZ 582876 A NZ582876 A NZ 582876A
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C12N15/1024—In vivo mutagenesis using high mutation rate "mutator" host strains by inserting genetic material, e.g. encoding an error prone polymerase, disrupting a gene for mismatch repair
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
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- C12P19/30—Nucleotides
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- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
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| US20150376590A1 (en) | 2012-11-02 | 2015-12-31 | Bp Corporation North America Inc. | Thermotolerant Beta-Glucosidase Variants |
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| US20200181666A1 (en) * | 2017-03-29 | 2020-06-11 | Editas Medicine, Inc. | Nucleic acid mutagenesis methods |
| US11542487B2 (en) | 2017-10-25 | 2023-01-03 | Basf Se | Beta-amylase enzymes |
| WO2019126211A1 (en) | 2017-12-20 | 2019-06-27 | Basf Se | Gene site saturation mutagenesis (gssm) method |
| US11634698B2 (en) | 2017-12-20 | 2023-04-25 | Basf Se | Nucleases and methods for making and using them |
| CN112368375A (zh) | 2018-04-26 | 2021-02-12 | 巴斯夫欧洲公司 | 脂肪酶 |
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| AU2019334671A1 (en) | 2018-09-07 | 2021-03-25 | Basf Plant Science Company Gmbh | Improved method for the production of high levels of PUFA in plants |
| WO2020049155A1 (en) | 2018-09-07 | 2020-03-12 | Basf Plant Science Company Gmbh | Improved method for the production of high levels of pufa in plants |
| WO2020049159A1 (en) | 2018-09-07 | 2020-03-12 | Basf Plant Science Company Gmbh | Improved method for the production of high levels of pufa in plants |
| EP3938504A1 (en) | 2019-03-11 | 2022-01-19 | Basf Se | Amylases and methods for making and using them |
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| KR20220119408A (ko) | 2019-12-20 | 2022-08-29 | 바스프 에스이 | 터펜의 독성 감소 및 미생물에서 생산 잠재성 증가 |
| EP4162061A1 (en) | 2020-06-04 | 2023-04-12 | Isobionics B.V. | Synthetic santalene synthases |
| EP4015626A1 (en) | 2020-12-18 | 2022-06-22 | Isobionics B.V. | Enzymes and methods for fermentative production of monoterpene esters |
| JP2024528957A (ja) | 2021-08-02 | 2024-08-01 | ビーエーエスエフ ソシエタス・ヨーロピア | イオニリデンエタンシンターゼによる新規な芳香化合物の生成 |
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| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4683195A (en) * | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US5849482A (en) | 1988-09-28 | 1998-12-15 | Epoch Pharmaceuticals, Inc. | Crosslinking oligonucleotides |
| EP1471142B1 (en) * | 1991-04-10 | 2008-11-19 | The Scripps Research Institute | Heterodimeric receptor libraries using phagemids |
| ATE239089T1 (de) * | 1991-12-24 | 2003-05-15 | Harvard College | Gezielte punkt-mutagenese von dna |
| US20030194807A1 (en) * | 1992-11-02 | 2003-10-16 | Roberto Crea | Walk-through mutagenesis |
| AU691194B2 (en) | 1993-06-25 | 1998-05-14 | Yale University | Chemically modified oligonucleotide for site-directed mutagenesis |
| US6165793A (en) * | 1996-03-25 | 2000-12-26 | Maxygen, Inc. | Methods for generating polynucleotides having desired characteristics by iterative selection and recombination |
| US6335160B1 (en) * | 1995-02-17 | 2002-01-01 | Maxygen, Inc. | Methods and compositions for polypeptide engineering |
| US6939689B2 (en) * | 1995-12-07 | 2005-09-06 | Diversa Corporation | Exonuclease-mediated nucleic acid reassembly in directed evolution |
| US6479258B1 (en) * | 1995-12-07 | 2002-11-12 | Diversa Corporation | Non-stochastic generation of genetic vaccines |
| US6740506B2 (en) * | 1995-12-07 | 2004-05-25 | Diversa Corporation | End selection in directed evolution |
| US6713279B1 (en) * | 1995-12-07 | 2004-03-30 | Diversa Corporation | Non-stochastic generation of genetic vaccines and enzymes |
| US6361974B1 (en) * | 1995-12-07 | 2002-03-26 | Diversa Corporation | Exonuclease-mediated nucleic acid reassembly in directed evolution |
| US6358709B1 (en) * | 1995-12-07 | 2002-03-19 | Diversa Corporation | End selection in directed evolution |
| US6238884B1 (en) * | 1995-12-07 | 2001-05-29 | Diversa Corporation | End selection in directed evolution |
| US5965408A (en) * | 1996-07-09 | 1999-10-12 | Diversa Corporation | Method of DNA reassembly by interrupting synthesis |
| US6562594B1 (en) * | 1999-09-29 | 2003-05-13 | Diversa Corporation | Saturation mutagenesis in directed evolution |
| US6764835B2 (en) * | 1995-12-07 | 2004-07-20 | Diversa Corporation | Saturation mutageneis in directed evolution |
| US6489145B1 (en) * | 1996-07-09 | 2002-12-03 | Diversa Corporation | Method of DNA shuffling |
| US6352842B1 (en) * | 1995-12-07 | 2002-03-05 | Diversa Corporation | Exonucease-mediated gene assembly in directed evolution |
| US6537776B1 (en) * | 1999-06-14 | 2003-03-25 | Diversa Corporation | Synthetic ligation reassembly in directed evolution |
| US20040023327A1 (en) * | 1995-12-07 | 2004-02-05 | Short Jay M. | End selection in directed evolution |
| US5830696A (en) * | 1996-12-05 | 1998-11-03 | Diversa Corporation | Directed evolution of thermophilic enzymes |
| US6171820B1 (en) | 1995-12-07 | 2001-01-09 | Diversa Corporation | Saturation mutagenesis in directed evolution |
| US20020028443A1 (en) * | 1999-09-27 | 2002-03-07 | Jay M. Short | Method of dna shuffling with polynucleotides produced by blocking or interrupting a synthesis or amplification process |
| US5789166A (en) | 1995-12-08 | 1998-08-04 | Stratagene | Circular site-directed mutagenesis |
| GB9701425D0 (en) * | 1997-01-24 | 1997-03-12 | Bioinvent Int Ab | A method for in vitro molecular evolution of protein function |
| US6949383B2 (en) * | 1998-11-11 | 2005-09-27 | Japan Science And Technology Corporation | Mutagenesis method |
| US6376191B1 (en) * | 2000-03-22 | 2002-04-23 | Mergen, Ltd. | Microarray-based analysis of polynucleotide sequence variations |
| JP3859947B2 (ja) * | 2000-08-04 | 2006-12-20 | 独立行政法人理化学研究所 | 突然変異導入方法 |
| DK1309677T4 (da) * | 2000-08-11 | 2012-06-25 | Genencor Int | Bacillustransformation, transformanter og mutantbiblioteker |
| FR2813314B1 (fr) | 2000-08-25 | 2004-05-07 | Biomethodes | Procede de mutagenese dirigee massive |
| USPP13969P3 (en) | 2001-04-05 | 2003-07-15 | Her Majesty The Queen In Right Of Canada As Represented By The Minister Of Agriculture | Shrub rose plant named ‘Morden Sunrise’ |
| JP4473573B2 (ja) | 2001-07-26 | 2010-06-02 | ストラタジーン カリフォルニア | 多部位突然変異誘発 |
| DE10148607A1 (de) * | 2001-10-02 | 2003-04-10 | Max Planck Gesellschaft | Methoden zur DNA-Manipulation |
| WO2003040376A1 (en) * | 2001-11-02 | 2003-05-15 | Olga Makarova | Method for site-directed mutagenesis of nucleic acid molecules using a single primer |
| JP2005511045A (ja) * | 2001-12-03 | 2005-04-28 | ディヴァーサ コーポレイション | 染色体飽和変異誘発 |
| AUPS263402A0 (en) * | 2002-05-29 | 2002-06-20 | Young, Lei | Targeted amplification of template strand (TATS) technology, and its use in DNA mutagenesis, deletion & insertion |
| US20060228786A1 (en) | 2003-02-06 | 2006-10-12 | Salerno John C | Polymerase-based protocols for the introduction of deletions and insertions |
| US20060134624A1 (en) * | 2003-02-06 | 2006-06-22 | Salerno John C | Polymerase-based protocols for the introductions of deletions and insertions |
| US6878531B1 (en) * | 2003-11-10 | 2005-04-12 | Medical College Of Georgia Research Institute | Method for multiple site-directed mutagenesis |
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- 2008-07-31 BR BRPI0815046-0A2A patent/BRPI0815046A2/pt not_active Application Discontinuation
- 2008-07-31 CN CN201510050333.XA patent/CN104673784A/zh active Pending
- 2008-07-31 ES ES16154206T patent/ES2701883T3/es active Active
- 2008-07-31 EA EA201070206A patent/EA020657B1/ru not_active IP Right Cessation
- 2008-07-31 NZ NZ582876A patent/NZ582876A/en not_active IP Right Cessation
- 2008-07-31 MX MX2010001182A patent/MX353478B/es active IP Right Grant
- 2008-07-31 JP JP2010520191A patent/JP6014805B2/ja not_active Expired - Fee Related
- 2008-07-31 CN CN200880101253.0A patent/CN101821402B/zh not_active Expired - Fee Related
- 2008-07-31 EP EP16154206.3A patent/EP3031919B1/en active Active
- 2008-07-31 DK DK16154206.3T patent/DK3031919T3/en active
- 2008-07-31 EP EP08782567A patent/EP2183378A4/en not_active Ceased
- 2008-07-31 US US12/671,231 patent/US9476078B2/en not_active Expired - Fee Related
- 2008-07-31 WO PCT/US2008/071771 patent/WO2009018449A1/en not_active Ceased
- 2008-07-31 AU AU2008282101A patent/AU2008282101A1/en not_active Abandoned
- 2008-07-31 CA CA2693102A patent/CA2693102C/en active Active
- 2008-07-31 KR KR1020107003986A patent/KR101685712B1/ko not_active Expired - Fee Related
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2009
- 2009-12-20 IL IL202839A patent/IL202839A0/en unknown
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- 2010-01-08 ZA ZA2010/00152A patent/ZA201000152B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR101685712B1 (ko) | 2016-12-12 |
| EP3031919A1 (en) | 2016-06-15 |
| EA201070206A1 (ru) | 2010-06-30 |
| DK3031919T3 (en) | 2019-01-07 |
| CA2693102C (en) | 2020-03-10 |
| IL202839A0 (en) | 2010-06-30 |
| JP6014805B2 (ja) | 2016-10-26 |
| CN104673784A (zh) | 2015-06-03 |
| CA2693102A1 (en) | 2009-02-05 |
| EP2183378A1 (en) | 2010-05-12 |
| US9476078B2 (en) | 2016-10-25 |
| EP3031919B1 (en) | 2018-09-19 |
| AU2008282101A1 (en) | 2009-02-05 |
| CN101821402B (zh) | 2015-03-04 |
| MX2010001182A (es) | 2010-04-21 |
| BRPI0815046A2 (pt) | 2014-10-14 |
| ZA201000152B (en) | 2011-06-29 |
| EA020657B1 (ru) | 2014-12-30 |
| ES2701883T3 (es) | 2019-02-26 |
| WO2009018449A1 (en) | 2009-02-05 |
| EP2183378A4 (en) | 2010-09-22 |
| JP2010535034A (ja) | 2010-11-18 |
| KR20100045494A (ko) | 2010-05-03 |
| MX353478B (es) | 2018-01-15 |
| CN101821402A (zh) | 2010-09-01 |
| US20100216192A1 (en) | 2010-08-26 |
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