NZ581742A - Biomarkers for predicting anti-tnf responsiveness or non-responsiveness - Google Patents
Biomarkers for predicting anti-tnf responsiveness or non-responsivenessInfo
- Publication number
- NZ581742A NZ581742A NZ581742A NZ58174208A NZ581742A NZ 581742 A NZ581742 A NZ 581742A NZ 581742 A NZ581742 A NZ 581742A NZ 58174208 A NZ58174208 A NZ 58174208A NZ 581742 A NZ581742 A NZ 581742A
- Authority
- NZ
- New Zealand
- Prior art keywords
- seq
- responsiveness
- subject
- expression level
- tnf
- Prior art date
Links
- 230000004043 responsiveness Effects 0.000 title 2
- 239000000090 biomarker Substances 0.000 title 1
- 102100035754 Biorientation of chromosomes in cell division protein 1-like 1 Human genes 0.000 abstract 2
- 102100035437 Ceramide transfer protein Human genes 0.000 abstract 2
- 102100032559 Clathrin light chain B Human genes 0.000 abstract 2
- 101000874052 Homo sapiens Biorientation of chromosomes in cell division protein 1-like 1 Proteins 0.000 abstract 2
- 101000737563 Homo sapiens Ceramide transfer protein Proteins 0.000 abstract 2
- 101000942271 Homo sapiens Clathrin light chain B Proteins 0.000 abstract 2
- 101000636210 Homo sapiens Matrix-remodeling-associated protein 7 Proteins 0.000 abstract 2
- 101000937725 Homo sapiens Protein FAM223A Proteins 0.000 abstract 2
- 101000793247 Homo sapiens Protein YIPF6 Proteins 0.000 abstract 2
- 101000587430 Homo sapiens Serine/arginine-rich splicing factor 2 Proteins 0.000 abstract 2
- 102100030775 Matrix-remodeling-associated protein 7 Human genes 0.000 abstract 2
- 102100027294 Protein FAM223A Human genes 0.000 abstract 2
- 102100030938 Protein YIPF6 Human genes 0.000 abstract 2
- 102100029666 Serine/arginine-rich splicing factor 2 Human genes 0.000 abstract 2
- 239000012472 biological sample Substances 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 238000002560 therapeutic procedure Methods 0.000 abstract 2
- 239000002451 tumor necrosis factor inhibitor Substances 0.000 abstract 2
- 208000026278 immune system disease Diseases 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/15—Medicinal preparations ; Physical properties thereof, e.g. dissolubility
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
- Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pathology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US94293707P | 2007-06-08 | 2007-06-08 | |
| PCT/US2008/066180 WO2008154423A2 (en) | 2007-06-08 | 2008-06-06 | Biomarkers for predicting anti-tnf responsiveness or non-responsiveness |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ581742A true NZ581742A (en) | 2012-09-28 |
Family
ID=40130456
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ581742A NZ581742A (en) | 2007-06-08 | 2008-06-06 | Biomarkers for predicting anti-tnf responsiveness or non-responsiveness |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20100303813A1 (https=) |
| EP (2) | EP2167687B1 (https=) |
| JP (2) | JP5719591B2 (https=) |
| KR (1) | KR20100037590A (https=) |
| CN (2) | CN101796197B (https=) |
| AU (1) | AU2008261869B2 (https=) |
| BR (1) | BRPI0812461A2 (https=) |
| CA (1) | CA2690898A1 (https=) |
| EA (1) | EA017815B1 (https=) |
| IL (2) | IL202562A0 (https=) |
| MX (1) | MX2009013410A (https=) |
| NO (1) | NO20093488L (https=) |
| NZ (1) | NZ581742A (https=) |
| SG (1) | SG182183A1 (https=) |
| WO (1) | WO2008154423A2 (https=) |
| ZA (1) | ZA200909215B (https=) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090235713A1 (en) * | 2008-03-24 | 2009-09-24 | Hirotec America, Inc. | Magnetically actuated roller head |
| US10236078B2 (en) | 2008-11-17 | 2019-03-19 | Veracyte, Inc. | Methods for processing or analyzing a sample of thyroid tissue |
| US8512964B2 (en) | 2008-12-12 | 2013-08-20 | The Regents Of The University Of California | Targets for treatment of hypercholesterolemia |
| JP4883117B2 (ja) * | 2009-03-23 | 2012-02-22 | コニカミノルタビジネステクノロジーズ株式会社 | 画像処理装置の課金装置、それを用いた画像処理装置、画像処理装置の課金装置の制御方法、及び画像処理装置の課金装置の制御プログラム |
| US8669057B2 (en) | 2009-05-07 | 2014-03-11 | Veracyte, Inc. | Methods and compositions for diagnosis of thyroid conditions |
| US8728730B2 (en) | 2009-09-03 | 2014-05-20 | Genentech, Inc. | Methods for treating, diagnosing, and monitoring rheumatoid arthritis |
| BR112012021576A2 (pt) | 2010-02-26 | 2016-10-25 | Novo Nordisk As | composições estáveis contendo anticorpo. |
| WO2011117366A2 (en) * | 2010-03-24 | 2011-09-29 | Tc Land Expression | Genes and genes combinations predictive of early response or non response of subjects suffering from inflammatory disease to cytokine targeting drugs (cytd) |
| RU2012153786A (ru) | 2010-05-28 | 2014-07-10 | Ново Нордиск А/С | Стабильные многодозовые композиции, содержащие антитело и консервант |
| BR112013021725A2 (pt) | 2011-02-28 | 2016-11-01 | Genentech Inc | marcadores biológicos e métodos para prever resposta aos antagonistas de células b |
| WO2013117751A2 (en) | 2012-02-10 | 2013-08-15 | Novo Nordisk A/S | Methods related to treatment of inflammatory diseases and disorders |
| US9031292B2 (en) * | 2012-04-19 | 2015-05-12 | Chang Gung University | Method for the diagnosis of neurodegenerative disorder by using diffusion kurtosis imaging |
| EP2861767A4 (en) * | 2012-06-15 | 2016-07-27 | Nuclea Biotechnologies Inc | PREDICTIVE MARKERS FOR CANCER AND METAL CHANGE SYNDROME |
| US11976329B2 (en) | 2013-03-15 | 2024-05-07 | Veracyte, Inc. | Methods and systems for detecting usual interstitial pneumonia |
| ES2524164B1 (es) * | 2013-05-03 | 2015-10-27 | Fundació Hospital Universitari Vall D'hebron - Institut De Recerca | Pronóstico de respuesta al tratamiento con anti-tnfalfa en pacientes de artritis reumatoide |
| US12297505B2 (en) | 2014-07-14 | 2025-05-13 | Veracyte, Inc. | Algorithms for disease diagnostics |
| US20170306402A1 (en) * | 2014-09-12 | 2017-10-26 | Biogen Ma Inc. | Systems and methods for characterization of multiple sclerosis |
| EP3215170A4 (en) | 2014-11-05 | 2018-04-25 | Veracyte, Inc. | Systems and methods of diagnosing idiopathic pulmonary fibrosis on transbronchial biopsies using machine learning and high dimensional transcriptional data |
| US10098168B2 (en) * | 2014-12-08 | 2018-10-09 | Apple Inc. | Neighbor awareness networking datapath |
| GB2547406A (en) * | 2015-11-20 | 2017-08-23 | Folkersen Lasse | Apparatus and methods of using of biomarkers for predicting TNF-inhibitor response |
| PT3384049T (pt) * | 2015-12-03 | 2023-08-18 | Regeneron Pharma | Método de associação de variantes genéticas com um resultado clínico em doentes que sofrem de degeneração macular relacionada à idade tratados com anti-vegf |
| GB201521357D0 (en) * | 2015-12-03 | 2016-01-20 | Univ Liverpool | Methods for predicting response to anti-TNF therapy |
| CN106520771B (zh) * | 2016-12-20 | 2019-02-12 | 江苏省人民医院 | 一种长非编码rna及其在诊断/治疗子痫前期中的应用 |
| WO2018119142A1 (en) | 2016-12-21 | 2018-06-28 | Amgen Inc. | Anti-tnf alpha antibody formulations |
| KR102094802B1 (ko) * | 2017-10-24 | 2020-03-31 | 고려대학교 산학협력단 | 소변 대사체 분석을 이용한 베체트병의 진단방법 |
| WO2019178546A1 (en) | 2018-03-16 | 2019-09-19 | Scipher Medicine Corporation | Methods and systems for predicting response to anti-tnf therapies |
| US11519020B2 (en) | 2018-05-25 | 2022-12-06 | Regeneron Pharmaceuticals, Inc. | Methods of associating genetic variants with a clinical outcome in patients suffering from age-related macular degeneration treated with anti-VEGF |
| CN110141578B (zh) * | 2019-06-10 | 2022-06-14 | 南通大学 | 环状RNA circ-Ankib1在制备促进神经再生和修复神经损伤药物中的应用 |
| GB2603294A (en) | 2019-06-27 | 2022-08-03 | Scipher Medicine Corp | Developing classifiers for stratifying patients |
| IL300978A (en) * | 2020-09-01 | 2023-04-01 | Scipher Medicine Corp | Methods and systems for predicting response to anti-TNF treatments |
| US12379368B2 (en) * | 2020-09-11 | 2025-08-05 | Washington University | Methods for determining therapeutic responsiveness for inflammatory bowel disease therapy |
| CN112180082B (zh) * | 2020-09-27 | 2022-03-08 | 西安交通大学 | Tweak在制备红斑狼疮诊断试剂中的应用 |
| RU2749247C1 (ru) * | 2020-09-28 | 2021-06-07 | федеральное государственное автономное образовательное учреждение высшего образования Первый Московский государственный медицинский университет имени И.М. Сеченова Министерства здравоохранения Российской Федерации (Сеченовский университет) (ФГАОУ ВО Первый МГМУ им. И.М. Сеченова Минздрава России (Се | Способ прогнозирования эффективности лечения ревматоидного артрита препаратом олокизумаб на основе генотипирования |
Family Cites Families (60)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4499052A (en) | 1982-08-30 | 1985-02-12 | Becton, Dickinson And Company | Apparatus for distinguishing multiple subpopulations of cells |
| US4582789A (en) | 1984-03-21 | 1986-04-15 | Cetus Corporation | Process for labeling nucleic acids using psoralen derivatives |
| US4563417A (en) | 1984-08-31 | 1986-01-07 | Miles Laboratories, Inc. | Nucleic acid hybridization assay employing antibodies to intercalation complexes |
| SE458968B (sv) | 1987-06-16 | 1989-05-22 | Wallac Oy | Biospecifikt analysfoerfarande foer flera analyter i vilket ingaar partikelraekning och maerkning med fluorescerande maerksubstanser |
| DK641487A (da) | 1987-12-07 | 1989-06-08 | Gluetech Aps | Fremgangsmaade til modificering af polymeroverflader |
| US5143854A (en) | 1989-06-07 | 1992-09-01 | Affymax Technologies N.V. | Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof |
| US5871928A (en) | 1989-06-07 | 1999-02-16 | Fodor; Stephen P. A. | Methods for nucleic acid analysis |
| US5547839A (en) | 1989-06-07 | 1996-08-20 | Affymax Technologies N.V. | Sequencing of surface immobilized polymers utilizing microflourescence detection |
| US5210015A (en) | 1990-08-06 | 1993-05-11 | Hoffman-La Roche Inc. | Homogeneous assay system using the nuclease activity of a nucleic acid polymerase |
| DE69132905T2 (de) | 1990-12-06 | 2002-08-01 | Affymetrix, Inc. (N.D.Ges.D.Staates Delaware) | Detektion von Nukleinsäuresequenzen |
| US5656272A (en) | 1991-03-18 | 1997-08-12 | New York University Medical Center | Methods of treating TNF-α-mediated Crohn's disease using chimeric anti-TNF antibodies |
| US5919452A (en) | 1991-03-18 | 1999-07-06 | New York University | Methods of treating TNFα-mediated disease using chimeric anti-TNF antibodies |
| US6270766B1 (en) | 1992-10-08 | 2001-08-07 | The Kennedy Institute Of Rheumatology | Anti-TNF antibodies and methotrexate in the treatment of arthritis and crohn's disease |
| AU6852594A (en) | 1993-06-03 | 1995-01-03 | Therapeutic Antibodies Inc. | Production of antibody fragments |
| US6027880A (en) | 1995-08-02 | 2000-02-22 | Affymetrix, Inc. | Arrays of nucleic acid probes and methods of using the same for detecting cystic fibrosis |
| US5888510A (en) | 1993-07-21 | 1999-03-30 | Chugai Seiyaku Kabushiki Kaisha | Chronic rheumatoid arthritis therapy containing IL-6 antagonist as effective component |
| FR2707882B1 (fr) | 1993-07-23 | 1997-08-01 | Immunotech Sa | Nouveaux kits thérapeutiques anti-médiateurs protéiques, procédé de préparation et compositions pharmaceutiques les renfermant. |
| US6156501A (en) | 1993-10-26 | 2000-12-05 | Affymetrix, Inc. | Arrays of modified nucleic acid probes and methods of use |
| US8017121B2 (en) | 1994-06-30 | 2011-09-13 | Chugai Seiyaku Kabushika Kaisha | Chronic rheumatoid arthritis therapy containing IL-6 antagonist as effective component |
| US5925351A (en) | 1995-07-21 | 1999-07-20 | Biogen, Inc. | Soluble lymphotoxin-β receptors and anti-lymphotoxin receptor and ligand antibodies as therapeutic agents for the treatment of immunological disease |
| US5981180A (en) | 1995-10-11 | 1999-11-09 | Luminex Corporation | Multiplexed analysis of clinical specimens apparatus and methods |
| AU3568897A (en) | 1996-06-07 | 1998-01-05 | Eos Biotechnology, Inc. | Immobilised linear oligonucleotide arrays |
| US7060667B1 (en) | 1998-01-30 | 2006-06-13 | Biogen Idec Ma, Inc. | Treatment of follicular lymphomas using inhibitors of the LT pathway |
| US6197599B1 (en) | 1998-07-30 | 2001-03-06 | Guorong Chin | Method to detect proteins |
| US7473528B2 (en) * | 1999-01-06 | 2009-01-06 | Genenews Inc. | Method for the detection of Chagas disease related gene transcripts in blood |
| US6410231B1 (en) | 1999-02-26 | 2002-06-25 | Incyte Genomics, Inc. | SNP detection |
| ATE412184T1 (de) | 1999-08-17 | 2008-11-15 | Luminex Corp | Verfahren zur analyse einer mehrzahl von proben verschiedenen ursprungs auf einen analyten |
| JP2003515149A (ja) | 1999-11-26 | 2003-04-22 | キュラジェン コーポレイション | 核酸プローブアレイ |
| CN1981868A (zh) | 2000-03-31 | 2007-06-20 | 拜奥根Idec公司 | 抗细胞因子抗体或拮抗剂与抗-cd20在b细胞淋巴瘤治疗中的联合应用 |
| WO2002046378A2 (en) * | 2000-12-08 | 2002-06-13 | Juan Saus | Alternative pol k nucleotide and amino acid sequence and methods for using |
| CN100523216C (zh) | 2001-03-02 | 2009-08-05 | 匹兹堡大学 | Pcr方法 |
| JP2004536290A (ja) | 2001-04-19 | 2004-12-02 | ゲゼルシャフト フュア バイオテクノロギッシェ フォーシュンク エム ベー ハー(ゲー ベー エフ) | 安定した、再生可能な抗体アレイの作製方法 |
| US6812341B1 (en) | 2001-05-11 | 2004-11-02 | Ambion, Inc. | High efficiency mRNA isolation methods and compositions |
| US6905827B2 (en) * | 2001-06-08 | 2005-06-14 | Expression Diagnostics, Inc. | Methods and compositions for diagnosing or monitoring auto immune and chronic inflammatory diseases |
| US20030013208A1 (en) | 2001-07-13 | 2003-01-16 | Milagen, Inc. | Information enhanced antibody arrays |
| US20040072181A1 (en) * | 2002-01-22 | 2004-04-15 | Whitehead Alexander Steven | Methods for determining drug responsiveness |
| JP4485949B2 (ja) | 2002-08-20 | 2010-06-23 | シヴェラ コーポレイション | マルチプレックス実験用の回折格子ベースのコード化マイクロパーティクル |
| US7126755B2 (en) | 2002-09-12 | 2006-10-24 | Moon John A | Method and apparatus for labeling using diffraction grating-based encoded optical identification elements |
| US7252976B2 (en) | 2002-08-28 | 2007-08-07 | Board Of Regents The University Of Texas System | Quantitative RT-PCR to AC133 to diagnose cancer and monitor angiogenic activity in a cell sample |
| JP4463104B2 (ja) | 2002-08-30 | 2010-05-12 | 財団法人化学及血清療法研究所 | ヒト抗ヒトインターロイキン−6抗体及び該抗体フラグメント |
| WO2004025560A1 (en) | 2002-09-12 | 2004-03-25 | Cyvera Corporation | Assay stick comprising coded microbeads |
| CA2498933C (en) | 2002-09-12 | 2012-08-28 | Cyvera Corporation | Method and apparatus for aligning elongated microbeads in order to interrogate the same |
| AU2003270726A1 (en) | 2002-09-12 | 2004-04-30 | Cidra Corporation | Diffraction grating-based encoded micro-particles for multiplexed experiments |
| US7092160B2 (en) | 2002-09-12 | 2006-08-15 | Illumina, Inc. | Method of manufacturing of diffraction grating-based optical identification element |
| WO2004025561A1 (en) | 2002-09-12 | 2004-03-25 | Cyvera Corporation | Chemical synthesis using diffraction grating-based encoded optical elements |
| GB2401040A (en) | 2003-04-28 | 2004-11-03 | Chugai Pharmaceutical Co Ltd | Method for treating interleukin-6 related diseases |
| JP4685369B2 (ja) * | 2004-04-30 | 2011-05-18 | 独立行政法人科学技術振興機構 | 関節リウマチ診断用試薬 |
| US20060008823A1 (en) | 2004-05-12 | 2006-01-12 | Kemp Jennifer T | DNA profiling and SNP detection utilizing microarrays |
| GT200500283A (es) * | 2004-10-08 | 2006-05-08 | Inmunoterapia de desordenes autoinmunes | |
| GB0422417D0 (en) * | 2004-10-08 | 2004-11-10 | Ihg Diagnostics | Improvements in induced heteroduplex generators |
| WO2006074399A2 (en) | 2005-01-05 | 2006-07-13 | Biogen Idec Ma Inc. | Multispecific binding molecules comprising connecting peptides |
| PE20061324A1 (es) | 2005-04-29 | 2007-01-15 | Centocor Inc | Anticuerpos anti-il-6, composiciones, metodos y usos |
| JP5339901B2 (ja) | 2005-05-10 | 2013-11-13 | バイオジェン・アイデック・エムエイ・インコーポレイテッド | 炎症傷害の処置および評価 |
| EP1907858A4 (en) * | 2005-06-13 | 2009-04-08 | Univ Michigan | COMPOSITIONS AND METHODS OF TREATMENT AND DIAGNOSIS OF CANCER |
| CN100338228C (zh) * | 2005-06-30 | 2007-09-19 | 卫生部北京医院 | 一种预测2型糖尿病易感性的试剂 |
| EP1929043A4 (en) * | 2005-08-24 | 2009-10-28 | Genizon Biosciences Inc | GENETIC CARD OF HUMAN GENES ASSOCIATED WITH CROHN'S DISEASE |
| WO2007038501A2 (en) * | 2005-09-27 | 2007-04-05 | The Feinstein Institute For Medical Research | Rheumatoid arthritis markers |
| EP1857559A1 (en) * | 2006-05-16 | 2007-11-21 | INSERM (Institut National de la Santé et de la Recherche Médicale) | A method for predicting responsiveness to TNF alpha blocking agents |
| US20080293582A1 (en) * | 2006-08-30 | 2008-11-27 | Xilin Li | Markers and Methods for Assessing and Treating Ulcerative Colitis and Related Disorders Using a 43 Gene Panel |
| WO2008132176A2 (en) * | 2007-04-27 | 2008-11-06 | Universite Catholique De Louvain | Method for evaluating the response of an individual to tnf blocking therapy |
-
2008
- 2008-06-06 JP JP2010511381A patent/JP5719591B2/ja active Active
- 2008-06-06 KR KR1020107000339A patent/KR20100037590A/ko not_active Ceased
- 2008-06-06 SG SG2012042255A patent/SG182183A1/en unknown
- 2008-06-06 CN CN200880102360.5A patent/CN101796197B/zh not_active Expired - Fee Related
- 2008-06-06 CA CA2690898A patent/CA2690898A1/en not_active Abandoned
- 2008-06-06 AU AU2008261869A patent/AU2008261869B2/en not_active Ceased
- 2008-06-06 BR BRPI0812461A patent/BRPI0812461A2/pt not_active Application Discontinuation
- 2008-06-06 EP EP08770385A patent/EP2167687B1/en active Active
- 2008-06-06 WO PCT/US2008/066180 patent/WO2008154423A2/en not_active Ceased
- 2008-06-06 MX MX2009013410A patent/MX2009013410A/es not_active Application Discontinuation
- 2008-06-06 EA EA200971131A patent/EA017815B1/ru not_active IP Right Cessation
- 2008-06-06 NZ NZ581742A patent/NZ581742A/xx not_active IP Right Cessation
- 2008-06-06 US US12/663,335 patent/US20100303813A1/en not_active Abandoned
- 2008-06-06 EP EP20130160408 patent/EP2617837A3/en not_active Withdrawn
- 2008-06-06 CN CN201410012312.4A patent/CN103710458A/zh active Pending
-
2009
- 2009-12-07 IL IL202562A patent/IL202562A0/en unknown
- 2009-12-08 NO NO20093488A patent/NO20093488L/no not_active Application Discontinuation
- 2009-12-23 ZA ZA200909215A patent/ZA200909215B/xx unknown
-
2012
- 2012-12-04 IL IL223419A patent/IL223419A0/en unknown
-
2013
- 2013-10-31 JP JP2013226708A patent/JP2014033676A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| US20100303813A1 (en) | 2010-12-02 |
| WO2008154423A2 (en) | 2008-12-18 |
| SG182183A1 (en) | 2012-07-30 |
| CN101796197A (zh) | 2010-08-04 |
| CN101796197B (zh) | 2014-02-12 |
| EA200971131A1 (ru) | 2010-06-30 |
| JP5719591B2 (ja) | 2015-05-20 |
| KR20100037590A (ko) | 2010-04-09 |
| EP2167687B1 (en) | 2013-03-27 |
| IL223419A0 (en) | 2013-02-03 |
| IL202562A0 (en) | 2011-08-01 |
| EP2167687A2 (en) | 2010-03-31 |
| CN103710458A (zh) | 2014-04-09 |
| EP2617837A2 (en) | 2013-07-24 |
| JP2010529464A (ja) | 2010-08-26 |
| BRPI0812461A2 (pt) | 2017-06-13 |
| ZA200909215B (en) | 2010-09-29 |
| JP2014033676A (ja) | 2014-02-24 |
| EA017815B1 (ru) | 2013-03-29 |
| MX2009013410A (es) | 2010-03-22 |
| NO20093488L (no) | 2010-01-08 |
| EP2617837A3 (en) | 2013-10-23 |
| CA2690898A1 (en) | 2008-12-18 |
| AU2008261869A1 (en) | 2008-12-18 |
| EP2167687A4 (en) | 2010-10-13 |
| WO2008154423A3 (en) | 2009-02-05 |
| AU2008261869B2 (en) | 2014-12-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NZ581742A (en) | Biomarkers for predicting anti-tnf responsiveness or non-responsiveness | |
| Deveau et al. | The mycorrhiza helper Pseudomonas fluorescens BBc6R8 has a specific priming effect on the growth, morphology and gene expression of the ectomycorrhizal fungus Laccaria bicolor S238N | |
| WO2010062960A3 (en) | METHODS OF DETERMINING RESPONSIVENESS TO ANTI-TNFα THERAPY IN INFLAMMATORY BOWEL DISEASE | |
| BRPI0507442B8 (pt) | método in vitro de diagnóstico de um indivíduo humano gestante como apresentando ou com uma propensão a desenvolver pré-eclâmpsia ou eclâmpsia | |
| Huang et al. | Expression analysis of type 2 metallothionein gene in mangrove species (Bruguiera gymnorrhiza) under heavy metal stress | |
| WO2008088854A3 (en) | Genetic markers for predicting responsiveness to combination therapy | |
| IN2012DN02485A (https=) | ||
| CA2812115C (en) | Epigenetic markers of colorectal cancers and diagnostic methods using the same | |
| WO2009086215A3 (en) | Pathway analysis of cell culture phenotypes and uses thereof | |
| WO2011038155A3 (en) | Genetic analysis | |
| WO2012118750A3 (en) | Biological markers and methods for predicting response to b-cell antagonists | |
| EP2374884A3 (en) | Human miRNAs isolated from mesenchymal stem cells | |
| WO2010036960A3 (en) | Methods for treating, diagnosing, and monitoring lupus | |
| WO2008048986A3 (en) | Gene array technique for predicting response in inflammatory bowel diseases | |
| WO2004097052A3 (en) | Methods for prognosis and treatment of solid tumors | |
| Ji et al. | Association of host genetics with intestinal microbial relevant to body weight in a chicken F2 resource population | |
| WO2010060996A3 (en) | Prediction of lipid-metabotype-related physiological susceptibilities | |
| WO2012061157A8 (en) | Method for high-throughput identification of microbial antagonists against pathogens | |
| WO2006074367A3 (en) | Method of predicting and reducing risk of metastasis of breast cancer to lung | |
| WO2007110623A3 (en) | Screening method | |
| WO2009055823A3 (en) | Method to predict responsiveness of breast cancer to polyaminetype chemotherapy | |
| Shen et al. | Differentiation of the fungus Histoplasma capsulatum into a pathogen of phagocytes | |
| MX2008013397A (es) | Analisis de perfilamiento de expresion diferencial de fenotipos de cultivo celular y usos de los mismos. | |
| WO2016130572A3 (en) | Methods of determining levels of exposure to radiation and uses thereof | |
| WO2004078035A3 (en) | Expression profiles for breast cancer and methods of use |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| S881 | Correction of error according section 88(1) (mistake in register by reason of an error or omission on the part of the patent office) |
Free format text: CORRECTION TO SPECIFICATION (51) |
|
| PSEA | Patent sealed | ||
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 3 YEARS UNTIL 06 JUN 2015 BY CULLEN + CO. Effective date: 20130109 |
|
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 06 JUN 2016 BY COMPUTER PACKAGES INC Effective date: 20150519 |
|
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 06 JUN 2017 BY COMPUTER PACKAGES INC Effective date: 20160518 |
|
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 06 JUN 2018 BY COMPUTER PACKAGES INC Effective date: 20170518 |
|
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 06 JUN 2019 BY RENEWALS TEAM Effective date: 20180518 |
|
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 06 JUN 2020 BY RENEWALS TEAM Effective date: 20190516 |
|
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 06 JUN 2021 BY CPA GLOBAL Effective date: 20200424 |
|
| LAPS | Patent lapsed |