NO20093488L - Biomarkorer for a predikere anti-TNF respons eller ikke-respons - Google Patents

Biomarkorer for a predikere anti-TNF respons eller ikke-respons

Info

Publication number
NO20093488L
NO20093488L NO20093488A NO20093488A NO20093488L NO 20093488 L NO20093488 L NO 20093488L NO 20093488 A NO20093488 A NO 20093488A NO 20093488 A NO20093488 A NO 20093488A NO 20093488 L NO20093488 L NO 20093488L
Authority
NO
Norway
Prior art keywords
response
tnf
biomarkers
predicting anti
person
Prior art date
Application number
NO20093488A
Other languages
English (en)
Inventor
Jadwiga Bienkowska
John P Carulli
Peter K Gregersen
Franak Batliwalla
Chunyu Liu
Original Assignee
The Feinstein Inst Medical Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Feinstein Inst Medical Res filed Critical The Feinstein Inst Medical Res
Publication of NO20093488L publication Critical patent/NO20093488L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/15—Medicinal preparations ; Physical properties thereof, e.g. dissolubility
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Den aktuelle offentliggjøringen gir biomarkører som er predikative av en persons respons eller ikke-respons til anti-TNF-behandling. Biomarkører, sammensetninger og metoder beskrevet i dette dokumentet er nyttige i å velge egnede behandlingsmodalititeter (f.eks. anti-TNF-behandling eller ikke-anti-TNF-behandling) for en person som lider av en sykdom som f.eks. en immunlidelse.
NO20093488A 2007-06-08 2009-12-08 Biomarkorer for a predikere anti-TNF respons eller ikke-respons NO20093488L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US94293707P 2007-06-08 2007-06-08
PCT/US2008/066180 WO2008154423A2 (en) 2007-06-08 2008-06-06 Biomarkers for predicting anti-tnf responsiveness or non-responsiveness

Publications (1)

Publication Number Publication Date
NO20093488L true NO20093488L (no) 2010-01-08

Family

ID=40130456

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20093488A NO20093488L (no) 2007-06-08 2009-12-08 Biomarkorer for a predikere anti-TNF respons eller ikke-respons

Country Status (16)

Country Link
US (1) US20100303813A1 (no)
EP (2) EP2167687B1 (no)
JP (2) JP5719591B2 (no)
KR (1) KR20100037590A (no)
CN (2) CN101796197B (no)
AU (1) AU2008261869B2 (no)
BR (1) BRPI0812461A2 (no)
CA (1) CA2690898A1 (no)
EA (1) EA017815B1 (no)
IL (2) IL202562A0 (no)
MX (1) MX2009013410A (no)
NO (1) NO20093488L (no)
NZ (1) NZ581742A (no)
SG (1) SG182183A1 (no)
WO (1) WO2008154423A2 (no)
ZA (1) ZA200909215B (no)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090235713A1 (en) * 2008-03-24 2009-09-24 Hirotec America, Inc. Magnetically actuated roller head
WO2010068918A2 (en) 2008-12-12 2010-06-17 The Regents Of The University Of California Novel targets for treatment of hypercholesterolemia
JP4883117B2 (ja) * 2009-03-23 2012-02-22 コニカミノルタビジネステクノロジーズ株式会社 画像処理装置の課金装置、それを用いた画像処理装置、画像処理装置の課金装置の制御方法、及び画像処理装置の課金装置の制御プログラム
EP3211094A3 (en) 2009-09-03 2017-11-01 F. Hoffmann-La Roche AG Methods for treating, diagnosing, and monitoring rheumatoid arthritis
BR112012021576A2 (pt) 2010-02-26 2016-10-25 Novo Nordisk As composições estáveis contendo anticorpo.
EP2550367B1 (en) * 2010-03-24 2017-03-22 TC LAND Expression Genes and genes combinations predictive of early response or non response of subjects suffering from inflammatory disease to cytokine targeting drugs (cytd)
CA2800188A1 (en) 2010-05-28 2011-12-01 Novo Nordisk A/S Stable multi-dose compositions comprising an antibody and a preservative
RU2013140975A (ru) 2011-02-28 2015-04-10 Дженентек, Инк. Биологические маркеры и способы прогнозирования восприимчивости к антагонистам в-клеток
CA2864133A1 (en) 2012-02-10 2013-08-15 Novo Nordisk A/S Methods related to treatment of inflammatory diseases and disorders
US9031292B2 (en) * 2012-04-19 2015-05-12 Chang Gung University Method for the diagnosis of neurodegenerative disorder by using diffusion kurtosis imaging
US20130338027A1 (en) * 2012-06-15 2013-12-19 Nuclea Biotechnologies, Inc. Predictive Markers For Cancer and Metabolic Syndrome
US11976329B2 (en) 2013-03-15 2024-05-07 Veracyte, Inc. Methods and systems for detecting usual interstitial pneumonia
ES2524164B1 (es) * 2013-05-03 2015-10-27 Fundació Hospital Universitari Vall D'hebron - Institut De Recerca Pronóstico de respuesta al tratamiento con anti-tnfalfa en pacientes de artritis reumatoide
WO2016040861A1 (en) * 2014-09-12 2016-03-17 Biogen Ma Inc. Systems and methods for characterization of multiple sclerosis
US20170335396A1 (en) 2014-11-05 2017-11-23 Veracyte, Inc. Systems and methods of diagnosing idiopathic pulmonary fibrosis on transbronchial biopsies using machine learning and high dimensional transcriptional data
US10098168B2 (en) * 2014-12-08 2018-10-09 Apple Inc. Neighbor awareness networking datapath
GB2547406A (en) * 2015-11-20 2017-08-23 Folkersen Lasse Apparatus and methods of using of biomarkers for predicting TNF-inhibitor response
WO2017096031A1 (en) 2015-12-03 2017-06-08 Regeneron Pharmaceuticals, Inc. Methods of associating genetic variants with a clinical outcome in patients suffering from age-related macular degeneration treated with anti-vegf
GB201521357D0 (en) * 2015-12-03 2016-01-20 Univ Liverpool Methods for predicting response to anti-TNF therapy
CN106520771B (zh) * 2016-12-20 2019-02-12 江苏省人民医院 一种长非编码rna及其在诊断/治疗子痫前期中的应用
KR102094802B1 (ko) * 2017-10-24 2020-03-31 고려대학교 산학협력단 소변 대사체 분석을 이용한 베체트병의 진단방법
EP3765634A4 (en) * 2018-03-16 2021-12-01 Scipher Medicine Corporation METHODS AND SYSTEMS FOR PREDICTING THE RESPONSE TO ANTI-TNF THERAPIES
CN110141578B (zh) * 2019-06-10 2022-06-14 南通大学 环状RNA circ-Ankib1在制备促进神经再生和修复神经损伤药物中的应用
MX2022000128A (es) 2019-06-27 2022-04-27 Scipher Medicine Corp Desarrollo de clasificadores para estratificar pacientes.
AU2021336781A1 (en) * 2020-09-01 2023-05-11 Scipher Medicine Corporation Methods and systems for predicting response to anti-tnf therapies
US20220082548A1 (en) * 2020-09-11 2022-03-17 Washington University Methods for determining therapeutic responsiveness for inflammatory bowel disease therapy
CN112180082B (zh) * 2020-09-27 2022-03-08 西安交通大学 Tweak在制备红斑狼疮诊断试剂中的应用
RU2749247C1 (ru) * 2020-09-28 2021-06-07 федеральное государственное автономное образовательное учреждение высшего образования Первый Московский государственный медицинский университет имени И.М. Сеченова Министерства здравоохранения Российской Федерации (Сеченовский университет) (ФГАОУ ВО Первый МГМУ им. И.М. Сеченова Минздрава России (Се Способ прогнозирования эффективности лечения ревматоидного артрита препаратом олокизумаб на основе генотипирования

Family Cites Families (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4499052A (en) 1982-08-30 1985-02-12 Becton, Dickinson And Company Apparatus for distinguishing multiple subpopulations of cells
US4582789A (en) 1984-03-21 1986-04-15 Cetus Corporation Process for labeling nucleic acids using psoralen derivatives
US4563417A (en) 1984-08-31 1986-01-07 Miles Laboratories, Inc. Nucleic acid hybridization assay employing antibodies to intercalation complexes
SE458968B (sv) 1987-06-16 1989-05-22 Wallac Oy Biospecifikt analysfoerfarande foer flera analyter i vilket ingaar partikelraekning och maerkning med fluorescerande maerksubstanser
DK641487A (da) 1987-12-07 1989-06-08 Gluetech Aps Fremgangsmaade til modificering af polymeroverflader
US5547839A (en) 1989-06-07 1996-08-20 Affymax Technologies N.V. Sequencing of surface immobilized polymers utilizing microflourescence detection
US5871928A (en) 1989-06-07 1999-02-16 Fodor; Stephen P. A. Methods for nucleic acid analysis
US5143854A (en) 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US5210015A (en) 1990-08-06 1993-05-11 Hoffman-La Roche Inc. Homogeneous assay system using the nuclease activity of a nucleic acid polymerase
EP0834575B1 (en) 1990-12-06 2001-11-28 Affymetrix, Inc. (a Delaware Corporation) Identification of nucleic acids in samples
US5919452A (en) 1991-03-18 1999-07-06 New York University Methods of treating TNFα-mediated disease using chimeric anti-TNF antibodies
US5656272A (en) 1991-03-18 1997-08-12 New York University Medical Center Methods of treating TNF-α-mediated Crohn's disease using chimeric anti-TNF antibodies
US6270766B1 (en) 1992-10-08 2001-08-07 The Kennedy Institute Of Rheumatology Anti-TNF antibodies and methotrexate in the treatment of arthritis and crohn's disease
NZ266838A (en) 1993-06-03 1997-02-24 Therapeutic Antibodies Inc Treatment of patients with anti-tnfalpha antibody, antibody fragment
US6027880A (en) 1995-08-02 2000-02-22 Affymetrix, Inc. Arrays of nucleic acid probes and methods of using the same for detecting cystic fibrosis
US5888510A (en) 1993-07-21 1999-03-30 Chugai Seiyaku Kabushiki Kaisha Chronic rheumatoid arthritis therapy containing IL-6 antagonist as effective component
FR2707882B1 (fr) 1993-07-23 1997-08-01 Immunotech Sa Nouveaux kits thérapeutiques anti-médiateurs protéiques, procédé de préparation et compositions pharmaceutiques les renfermant.
US6156501A (en) 1993-10-26 2000-12-05 Affymetrix, Inc. Arrays of modified nucleic acid probes and methods of use
US8017121B2 (en) 1994-06-30 2011-09-13 Chugai Seiyaku Kabushika Kaisha Chronic rheumatoid arthritis therapy containing IL-6 antagonist as effective component
US5925351A (en) 1995-07-21 1999-07-20 Biogen, Inc. Soluble lymphotoxin-β receptors and anti-lymphotoxin receptor and ligand antibodies as therapeutic agents for the treatment of immunological disease
US5981180A (en) 1995-10-11 1999-11-09 Luminex Corporation Multiplexed analysis of clinical specimens apparatus and methods
WO1997046313A1 (en) 1996-06-07 1997-12-11 Eos Biotechnology, Inc. Immobilised linear oligonucleotide arrays
US7060667B1 (en) 1998-01-30 2006-06-13 Biogen Idec Ma, Inc. Treatment of follicular lymphomas using inhibitors of the LT pathway
US6197599B1 (en) 1998-07-30 2001-03-06 Guorong Chin Method to detect proteins
US7473528B2 (en) * 1999-01-06 2009-01-06 Genenews Inc. Method for the detection of Chagas disease related gene transcripts in blood
US6410231B1 (en) 1999-02-26 2002-06-25 Incyte Genomics, Inc. SNP detection
WO2001013120A1 (en) 1999-08-17 2001-02-22 Luminex Corporation Microparticles with multiple fluorescent signals and methods of using same
AU783841B2 (en) 1999-11-26 2005-12-15 454 Life Sciences Corporation Nucleic acid probe arrays
AU8729101A (en) 2000-03-31 2001-10-15 Idec Pharma Corp Combined use of anti-cytokine antibodies or antagonists and anti-CD20 for the treatment of B cell lymphoma
AU2002219164A1 (en) * 2000-12-08 2002-06-18 Juan Saus Tnf-inducible promotors and methods for using them
US7101663B2 (en) 2001-03-02 2006-09-05 University of Pittsburgh—of the Commonwealth System of Higher Education PCR method
JP2004536290A (ja) 2001-04-19 2004-12-02 ゲゼルシャフト　フュア　バイオテクノロギッシェ　フォーシュンク　エム　ベー　ハー（ゲー　ベー　エフ） 安定した、再生可能な抗体アレイの作製方法
US6812341B1 (en) 2001-05-11 2004-11-02 Ambion, Inc. High efficiency mRNA isolation methods and compositions
US6905827B2 (en) * 2001-06-08 2005-06-14 Expression Diagnostics, Inc. Methods and compositions for diagnosing or monitoring auto immune and chronic inflammatory diseases
US20030013208A1 (en) 2001-07-13 2003-01-16 Milagen, Inc. Information enhanced antibody arrays
AU2003212822A1 (en) * 2002-01-22 2003-09-02 Trustees Of The University Of Pennsylvania Methods for determining drug responsiveness
CA2496296A1 (en) 2002-08-20 2004-03-04 Cyvera Corporation Diffraction grating-based encoded micro-particles for multiplexed experiments
US7399643B2 (en) 2002-09-12 2008-07-15 Cyvera Corporation Method and apparatus for aligning microbeads in order to interrogate the same
US7126755B2 (en) 2002-09-12 2006-10-24 Moon John A Method and apparatus for labeling using diffraction grating-based encoded optical identification elements
US7252976B2 (en) 2002-08-28 2007-08-07 Board Of Regents The University Of Texas System Quantitative RT-PCR to AC133 to diagnose cancer and monitor angiogenic activity in a cell sample
EP1536012A4 (en) 2002-08-30 2006-03-08 Chemo Sero Therapeut Res Inst HUMAN-TYPE ANTIHUMAN INTERLEUKIN-6 ANTIBODY ANTIBODY ANTIBODY FRAGMENT
EP1540590A1 (en) 2002-09-12 2005-06-15 Cyvera Corporation Assay stick comprising coded microbeads
WO2004025561A1 (en) 2002-09-12 2004-03-25 Cyvera Corporation Chemical synthesis using diffraction grating-based encoded optical elements
US7092160B2 (en) 2002-09-12 2006-08-15 Illumina, Inc. Method of manufacturing of diffraction grating-based optical identification element
EP1540591A1 (en) 2002-09-12 2005-06-15 Cyvera Corporation Diffraction grating-based encoded micro-particles for multiplexed experiments
GB2401040A (en) 2003-04-28 2004-11-03 Chugai Pharmaceutical Co Ltd Method for treating interleukin-6 related diseases
JP4685369B2 (ja) * 2004-04-30 2011-05-18 独立行政法人科学技術振興機構 関節リウマチ診断用試薬
US20060008823A1 (en) 2004-05-12 2006-01-12 Kemp Jennifer T DNA profiling and SNP detection utilizing microarrays
GB0422417D0 (en) * 2004-10-08 2004-11-10 Ihg Diagnostics Improvements in induced heteroduplex generators
SV2006002258A (es) * 2004-10-08 2006-09-19 Wyeth Corp Inmunoterapia de trastornos autoinmunes
WO2006074399A2 (en) 2005-01-05 2006-07-13 Biogen Idec Ma Inc. Multispecific binding molecules comprising connecting peptides
PA8672101A1 (es) 2005-04-29 2006-12-07 Centocor Inc Anticuerpos anti-il-6, composiciones, métodos y usos
AU2006244014B2 (en) 2005-05-10 2011-03-17 Biogen Ma Inc. Treating and evaluating inflammatory disorders
WO2006138275A2 (en) * 2005-06-13 2006-12-28 The Regents Of The University Of Michigan Compositions and methods for treating and diagnosing cancer
CN100338228C (zh) * 2005-06-30 2007-09-19 卫生部北京医院 一种预测2型糖尿病易感性的试剂
EP1929043A4 (en) * 2005-08-24 2009-10-28 Genizon Biosciences Inc GENETIC CARD OF HUMAN GENES ASSOCIATED WITH CROHN'S DISEASE
WO2007038501A2 (en) * 2005-09-27 2007-04-05 The Feinstein Institute For Medical Research Rheumatoid arthritis markers
EP1857559A1 (en) * 2006-05-16 2007-11-21 INSERM (Institut National de la Santé et de la Recherche Médicale) A method for predicting responsiveness to TNF alpha blocking agents
US20080293582A1 (en) * 2006-08-30 2008-11-27 Xilin Li Markers and Methods for Assessing and Treating Ulcerative Colitis and Related Disorders Using a 43 Gene Panel
WO2008132176A2 (en) * 2007-04-27 2008-11-06 Universite Catholique De Louvain Method for evaluating the response of an individual to tnf blocking therapy

Also Published As

Publication number Publication date
SG182183A1 (en) 2012-07-30
AU2008261869B2 (en) 2014-12-18
JP2010529464A (ja) 2010-08-26
IL223419A0 (en) 2013-02-03
NZ581742A (en) 2012-09-28
CN101796197B (zh) 2014-02-12
EP2617837A3 (en) 2013-10-23
US20100303813A1 (en) 2010-12-02
WO2008154423A2 (en) 2008-12-18
EA200971131A1 (ru) 2010-06-30
MX2009013410A (es) 2010-03-22
WO2008154423A3 (en) 2009-02-05
EP2617837A2 (en) 2013-07-24
EP2167687B1 (en) 2013-03-27
ZA200909215B (en) 2010-09-29
JP2014033676A (ja) 2014-02-24
CN103710458A (zh) 2014-04-09
EP2167687A2 (en) 2010-03-31
CN101796197A (zh) 2010-08-04
EA017815B1 (ru) 2013-03-29
BRPI0812461A2 (pt) 2017-06-13
AU2008261869A1 (en) 2008-12-18
CA2690898A1 (en) 2008-12-18
EP2167687A4 (en) 2010-10-13
IL202562A0 (en) 2011-08-01
KR20100037590A (ko) 2010-04-09
JP5719591B2 (ja) 2015-05-20

Similar Documents

Publication Publication Date Title
NO20093488L (no) Biomarkorer for a predikere anti-TNF respons eller ikke-respons
MX2009009261A (es) Anticuerpos anti-ip-10 y metodos para su uso.
CY1121327T1 (el) Τροποποιημενα αντισωματα anti-il-23p19
MY150709A (en) Human cytomegalovirus neutralising antibodies and use thereof
GB2478065A (en) Method and systems for personalized action plans
WO2009117122A3 (en) Genetic analysis
MX2014006158A (es) Metodos para el tratamiento de artritis psoriasica (psa) utilizando antagonistas de il-17 y alelos con respuesta o sin respuesta a la psa.
CY1114019T1 (el) Μεταλλακτες του αντισωματος anti-cd40
NO20073882L (no) Human anti-interferon gamma antistoffer og fremgangsmater for anvendelser derav
EA201590833A1 (ru) Антитела для лечения и профилактики болезни альцгеймера и их применение
NO20065560L (no) Anvendelse av IL-17-uttrykking for a forutsi hudinflammasjon, fremgangsmater for behandling.
MY154984A (en) Preventing autoimmune disease
MX2020010947A (es) Metodos de tratamiento de enfermedad de alzheimer.
IL171356A (en) Anti-interferon receptor antibody for treatment of inflammatory bowel disease
Siebenhaar et al. Successful treatment of cutaneous mastocytosis and Meniere disease with anti-IgE therapy
WO2007022374A3 (en) Assessing response to anti-cd20 therapy by genotyping c1q components
WO2006108094A3 (en) Organ homing genes of cancer metastases
Hussain Biosafety outside laboratories
Butylin et al. Calreticulin Mutations Variants of ET and PMF Patients Studied in Almazov Medical Research Center Russian Federation
Zhang et al. P043 HLA-DP donor specific antibodies associated with antibody mediated rejection and poor allograft survival following lung transplant
van der Donk et al. Depressive symptoms in cancer patients and healthy controls: differences and similarities
Kuo et al. Optimal two‐stage breast cancer screening for countries with intermediate or low incidence of breast cancer
Kopchaliiska et al. OR20 Characterization of de novo donor-specific HLA ANTIBODIES AND correlation with C4d+ antibody-mediated rejection of kidney transplants
WO2008143879A3 (en) Vitamin e supplementation for reducing cardiovascular events in individuals with dm and the hp 2-2 genotype
Smith et al. Wheelchair and Scooter Use and Access in Canada: Prevalence and Policy

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application