NZ528034A - Isothiazoloanthrones, isoxazoloanthrones, isoindolanthrones and derivatives thereof as JNK inhibitors and compositions and methods related thereto - Google Patents
Isothiazoloanthrones, isoxazoloanthrones, isoindolanthrones and derivatives thereof as JNK inhibitors and compositions and methods related theretoInfo
- Publication number
- NZ528034A NZ528034A NZ528034A NZ52803402A NZ528034A NZ 528034 A NZ528034 A NZ 528034A NZ 528034 A NZ528034 A NZ 528034A NZ 52803402 A NZ52803402 A NZ 52803402A NZ 528034 A NZ528034 A NZ 528034A
- Authority
- NZ
- New Zealand
- Prior art keywords
- compound
- substituent
- pharmaceutically acceptable
- acceptable salt
- exemplified
- Prior art date
Links
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Classifications
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- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
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Landscapes
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26901301P | 2001-02-15 | 2001-02-15 | |
| US10/071,390 US6987184B2 (en) | 2001-02-15 | 2002-02-07 | Isothiazoloanthrones, isoxazoloanthrones, isoindolanthrones and derivatives thereof as JNK inhibitors and compositions and methods related |
| PCT/US2002/004283 WO2002066450A2 (en) | 2001-02-15 | 2002-02-13 | Anthrone derivatives and their use as ink inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ528034A true NZ528034A (en) | 2005-12-23 |
Family
ID=26752159
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ528034A NZ528034A (en) | 2001-02-15 | 2002-02-13 | Isothiazoloanthrones, isoxazoloanthrones, isoindolanthrones and derivatives thereof as JNK inhibitors and compositions and methods related thereto |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US6987184B2 (https=) |
| EP (1) | EP1363891A2 (https=) |
| JP (1) | JP2004526711A (https=) |
| CA (1) | CA2438312A1 (https=) |
| NZ (1) | NZ528034A (https=) |
| WO (1) | WO2002066450A2 (https=) |
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| ATE465153T1 (de) | 2002-02-28 | 2010-05-15 | Eisai R&D Man Co Ltd | Neue indazolverbindungen mit kondensiertem ring |
| WO2003075917A1 (en) | 2002-03-08 | 2003-09-18 | Signal Pharmaceuticals, Inc. | Combination therapy for treating, preventing or managing proliferative disorders and cancers |
| JP2005522215A (ja) * | 2002-04-12 | 2005-07-28 | セルジーン・コーポレーション | 幹細胞及び前駆細胞の分化のモジュレーション、アッセイ、並びにそれらの使用 |
| US20040034084A1 (en) * | 2002-05-24 | 2004-02-19 | Celgene Corporation | Methods for using JNK inhibitors for treating or preventing disease-related wasting |
| CN1668733A (zh) * | 2002-05-30 | 2005-09-14 | 细胞基因公司 | 利用jnk或mkk抑制剂调节细胞分化并治疗骨髓增生异常和脊髓发育不良综合症的方法 |
| US20040087642A1 (en) * | 2002-10-24 | 2004-05-06 | Zeldis Jerome B. | Methods of using and compositions comprising a JNK inhibitor for the treatment, prevention, management and/or modification of pain |
| NZ540546A (en) * | 2002-11-18 | 2008-03-28 | Celgene Corp | Methods of using and compositions comprising (-)-3-(3,4-dimethoxy-phenyl)-3-(1-oxo-1,3-dihydro-isoindol-2-yl)-propionamide |
| EP1581205A1 (en) * | 2002-11-18 | 2005-10-05 | Celgene Corporation | Methods of using and compositions comprising (+)-3-(3,4-dimethoxy-phenyl)-3-(1-oxo-1,3-dihydro-isoindol-2-yl)-propionamide |
| AU2003298775B2 (en) * | 2002-11-26 | 2008-07-17 | Anthrogenesis Corporation | Cytotherapeutics, cytotherapeutic units and methods for treatments using them |
| US20050019366A1 (en) * | 2002-12-31 | 2005-01-27 | Zeldis Jerome B. | Drug-coated stents and methods of use therefor |
| WO2004071283A2 (en) * | 2003-02-13 | 2004-08-26 | Anthrogenesis Corporation | Use of umbilical cord blood to treat individuals having a disease, disorder or condition |
| KR20060124610A (ko) * | 2003-11-06 | 2006-12-05 | 셀진 코포레이션 | 석면-관련된 질환 또는 장애를 치료 및 관리하기 위하여ｊｎｋ 억제제를 사용하는 방법 및 이 물질을 포함하는조성물 |
| KR20060109979A (ko) * | 2003-12-02 | 2006-10-23 | 셀진 코포레이션 | 혈색소병증 및 빈혈의 치료 및 관리를 위한 방법및 조성물 |
| US20050266391A1 (en) * | 2004-01-15 | 2005-12-01 | Bennett Brydon L | Methods for preserving tissue |
| WO2005074921A1 (en) * | 2004-02-09 | 2005-08-18 | University Of Zurich | Treatment of atherosclerosis |
| JP4219289B2 (ja) * | 2004-03-10 | 2009-02-04 | 独立行政法人科学技術振興機構 | 多環性ケトン化合物及びその製造方法 |
| EP1676574A3 (en) | 2004-12-30 | 2006-07-26 | Johnson & Johnson Vision Care, Inc. | Methods for promoting survival of transplanted tissues and cells |
| WO2006090698A1 (ja) * | 2005-02-22 | 2006-08-31 | Ono Pharmaceutical Co., Ltd. | キナーゼ阻害薬およびその用途 |
| US20060223807A1 (en) * | 2005-03-29 | 2006-10-05 | University Of Massachusetts Medical School, A Massachusetts Corporation | Therapeutic methods for type I diabetes |
| DK1957633T3 (en) | 2005-10-13 | 2014-03-17 | Anthrogenesis Corp | Immunomodulation USING PLACE SPEECH STEM CELLS |
| CA2633980A1 (en) * | 2005-12-29 | 2007-07-12 | Anthrogenesis Corporation | Improved composition for collecting and preserving placental stem cells and methods of using the composition |
| WO2007093873A1 (en) * | 2006-02-13 | 2007-08-23 | Council Of Scientific And Industrial Research | Bis-pyrr0l0[2,l-c] [1, 4] benzodiazepine- anthraquinone conjugates as antitumour agents and a process for the preparation thereof |
| EP3763376A1 (en) * | 2007-02-12 | 2021-01-13 | Celularity, Inc. | Treatment of inflammatory diseases using placental stem cells |
| US20100239500A1 (en) * | 2007-03-30 | 2010-09-23 | Bixby John L | Substituted triazine compounds for nerve regeneration |
| WO2009111264A2 (en) * | 2008-02-29 | 2009-09-11 | Alseres Pharmaceuticals, Inc. | Systemic purine administration:modulating axonal outgrowth of central nervous system neurons |
| US8362020B2 (en) | 2009-12-30 | 2013-01-29 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| EP2598864B1 (en) * | 2010-07-26 | 2024-06-12 | Parker-Hannifin Corporation | Electrode, analyte sensor and method for preparing an electrode |
| US8969315B2 (en) | 2010-12-31 | 2015-03-03 | Anthrogenesis Corporation | Enhancement of placental stem cell potency using modulatory RNA molecules |
| JP6104896B2 (ja) | 2011-06-01 | 2017-03-29 | アントフロゲネシス コーポレーション | 胎盤幹細胞を使用する疼痛の治療 |
| EP3328819B1 (en) * | 2015-07-28 | 2020-04-01 | Beta Cat Pharmaceuticals, Inc. | Anthracene-9, 10-dione dioxime compounds prodrugs and their uses |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2733976A (en) * | 1956-02-07 | Sulfonateds-acylamino | ||
| GB355597A (en) | 1929-11-12 | 1931-08-27 | Ig Farbenindustrie Ag | Manufacture of carboxylic acid derivatives of the anthraquinone series |
| DE1026315B (de) * | 1954-08-17 | 1958-03-20 | Bayer Ag | Verfahren zur Herstellung von Acylamino-amino-anthrachinonen |
| US3095415A (en) * | 1958-05-30 | 1963-06-25 | Ciba Ltd | Anthraquinone dyestuffs containing a 2-chloro, 4-hydroxy (lower) alkylamino, triazinylamino group |
| DE1164003B (de) * | 1961-08-05 | 1964-02-27 | Bayer Ag | Verfahren zur Herstellung von Anthrachinonfarbstoffen |
| GB960235A (en) * | 1961-08-08 | 1964-06-10 | Ici Ltd | New disperse dyestuffs of the polycyclic ketone series |
| CH428043A (fr) * | 1965-08-16 | 1967-01-15 | Sandoz Ag | Procédé de fabrication de colorants de dispersion isothiazolantroniques |
| CH538527A (de) | 1968-11-07 | 1973-06-30 | Hoechst Ag | Verfahren zur Herstellung von faserreaktiven Farbstoffen |
| DE2200127A1 (de) | 1972-01-03 | 1973-07-12 | Basf Ag | Verfahren zur herstellung von dichlor1,1'-dianthrachinonylen und deren derivaten |
| DE2558813C2 (de) * | 1975-12-27 | 1984-10-31 | Hoechst Ag, 6230 Frankfurt | Lichtempfindliches Gemisch mit synergistischem Initiatorsystem |
| DE2558812C2 (de) * | 1975-12-27 | 1987-04-30 | Hoechst Ag, 6230 Frankfurt | Photopolymerisierbares Gemisch |
| US4198518A (en) | 1977-09-02 | 1980-04-15 | Ciba-Geigy Corporation | Process for the production of 3-substituted pyrazolanthrones |
| DE2950876A1 (de) * | 1979-12-18 | 1981-06-25 | Bayer Ag, 5090 Leverkusen | Verfahren zur herstellung von triazinylamino-anthrachinonen |
| JPS6028454A (ja) * | 1983-07-27 | 1985-02-13 | Mitsubishi Chem Ind Ltd | アントロン系化合物及び反応性アントロン系染料 |
| JPH0625311B2 (ja) | 1985-07-09 | 1994-04-06 | 住友化学工業株式会社 | 分散型水不溶性染料組成物 |
| JP2001502315A (ja) * | 1996-10-10 | 2001-02-20 | プローブ・インターナショナル | ウイルス感染を処置するための組成物および方法 |
| US6162613A (en) | 1998-02-18 | 2000-12-19 | Vertex Pharmaceuticals, Inc. | Methods for designing inhibitors of serine/threonine-kinases and tyrosine kinases |
| DE69900847T2 (de) | 1998-04-17 | 2002-09-12 | Tufts College | Map kinase-inhibitoren zur behandlung von durch tnf-alpha induzierte lipolyse- verursachte krankheiten |
| AU3786899A (en) | 1998-05-04 | 1999-11-23 | Vertex Pharmaceuticals Incorporated | Crystallizable jnk complexes |
| CN1136217C (zh) | 1998-12-17 | 2004-01-28 | 霍夫曼-拉罗奇有限公司 | 作为jnk蛋白质激酶抑制剂的4-芳基羟吲哚 |
| DE60041763D1 (de) | 1999-04-23 | 2009-04-23 | Vertex Pharma | Inhibitoren von c-jun n-terminal kinasen (jnk) |
| AU5316900A (en) | 1999-06-03 | 2000-12-28 | Vertex Pharmaceuticals Incorporated | Inhibitors of c-jun n-terminal kinases (jnk) |
| BR0013551A (pt) | 1999-08-13 | 2003-06-17 | Vertex Pharma | Inibidores de cinases n-terminal cjun (jnk) e outras cinases de proteìnas |
| EP1390052A4 (en) | 2001-04-24 | 2008-10-08 | Harvard College | INHIBITION OF JUN KINASE |
-
2002
- 2002-02-07 US US10/071,390 patent/US6987184B2/en not_active Expired - Fee Related
- 2002-02-13 WO PCT/US2002/004283 patent/WO2002066450A2/en not_active Ceased
- 2002-02-13 NZ NZ528034A patent/NZ528034A/en unknown
- 2002-02-13 CA CA002438312A patent/CA2438312A1/en not_active Abandoned
- 2002-02-13 JP JP2002565966A patent/JP2004526711A/ja active Pending
- 2002-02-13 EP EP02720975A patent/EP1363891A2/en not_active Withdrawn
-
2003
- 2003-04-04 US US10/407,107 patent/US20040092562A1/en not_active Abandoned
-
2005
- 2005-06-22 US US11/159,592 patent/US7354947B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP1363891A2 (en) | 2003-11-26 |
| US20060004080A1 (en) | 2006-01-05 |
| US7354947B2 (en) | 2008-04-08 |
| JP2004526711A (ja) | 2004-09-02 |
| CA2438312A1 (en) | 2002-08-29 |
| US20030073732A1 (en) | 2003-04-17 |
| WO2002066450A2 (en) | 2002-08-29 |
| WO2002066450A3 (en) | 2002-12-05 |
| US6987184B2 (en) | 2006-01-17 |
| US20040092562A1 (en) | 2004-05-13 |
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| Date | Code | Title | Description |
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| RENW | Renewal (renewal fees accepted) | ||
| PSEA | Patent sealed |