NZ511617A - DNA encoding OB protein and uses thereof - Google Patents
DNA encoding OB protein and uses thereofInfo
- Publication number
- NZ511617A NZ511617A NZ511617A NZ51161796A NZ511617A NZ 511617 A NZ511617 A NZ 511617A NZ 511617 A NZ511617 A NZ 511617A NZ 51161796 A NZ51161796 A NZ 51161796A NZ 511617 A NZ511617 A NZ 511617A
- Authority
- NZ
- New Zealand
- Prior art keywords
- protein
- amino acid
- human
- fusion protein
- amino acids
- Prior art date
Links
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Applications Claiming Priority (2)
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| NZ527007A NZ527007A (en) | 1995-11-22 | 1996-11-04 | Methods of increasing lean tissue mass using OB protein compositions |
| NZ512083A NZ512083A (en) | 1995-11-22 | 1996-11-04 | Methods of increasing lean tissue mass using OB protein compositions |
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| NZ527007A NZ527007A (en) | 1995-11-22 | 1996-11-04 | Methods of increasing lean tissue mass using OB protein compositions |
| NZ512083A NZ512083A (en) | 1995-11-22 | 1996-11-04 | Methods of increasing lean tissue mass using OB protein compositions |
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| EP (3) | EP1285664B1 (enExample) |
| JP (2) | JP4173914B2 (enExample) |
| AT (2) | ATE455554T1 (enExample) |
| AU (3) | AU7607496A (enExample) |
| CA (2) | CA2358862A1 (enExample) |
| DE (2) | DE69631544T2 (enExample) |
| DK (1) | DK0866720T3 (enExample) |
| ES (2) | ES2339846T3 (enExample) |
| IL (2) | IL124442A0 (enExample) |
| MX (1) | MX9803992A (enExample) |
| NZ (3) | NZ511617A (enExample) |
| PT (1) | PT866720E (enExample) |
| SI (1) | SI0866720T1 (enExample) |
| WO (1) | WO1997018833A1 (enExample) |
| ZA (1) | ZA969605B (enExample) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6001968A (en) | 1994-08-17 | 1999-12-14 | The Rockefeller University | OB polypeptides, modified forms and compositions |
| US20030040467A1 (en) | 1998-06-15 | 2003-02-27 | Mary Ann Pelleymounter | Ig/ob fusions and uses thereof. |
| CA2358862A1 (en) * | 1995-11-22 | 1997-05-29 | Amgen Inc. | Methods of increasing lean tissue mass using ob protein compositions |
| US6936439B2 (en) | 1995-11-22 | 2005-08-30 | Amgen Inc. | OB fusion protein compositions and methods |
| US6620413B1 (en) | 1995-12-27 | 2003-09-16 | Genentech, Inc. | OB protein-polymer chimeras |
| US20050019325A1 (en) | 1996-01-08 | 2005-01-27 | Carter Paul J. | WSX receptor agonist antibodies |
| US6541604B1 (en) | 1996-01-08 | 2003-04-01 | Genentech, Inc. | Leptin receptor having a WSX motif |
| US7074397B1 (en) | 1996-01-08 | 2006-07-11 | Genentech, Inc. | Method for enhancing proliferation or differentiation of a cell using ob protein |
| AU2246097A (en) * | 1996-01-25 | 1997-08-20 | Eli Lilly And Company | Obesity protein analog compounds and formulations thereof |
| JP2000509377A (ja) * | 1996-04-19 | 2000-07-25 | ザイモジェネティクス，インコーポレイティド | 骨形成を誘発するための方法 |
| CA2274799A1 (en) * | 1996-12-20 | 1998-07-02 | Eli Lilly And Company | Anti-obesity proteins |
| CA2275183A1 (en) * | 1996-12-20 | 1998-07-02 | Amgen Inc. | Ob fusion protein compositions and methods |
| US20020019352A1 (en) * | 1997-04-17 | 2002-02-14 | David N. Brems | Stable, active, human ob protein compositions and methods |
| EP0950417A3 (en) | 1998-02-23 | 2000-02-23 | Pfizer Products Inc. | Treatment of skeletal disorders |
| WO1999053939A1 (en) * | 1998-04-20 | 1999-10-28 | Mayo Foundation For Medical Education And Research | Treatment of osteoporosis with leptin |
| US6210924B1 (en) | 1998-08-11 | 2001-04-03 | Amgen Inc. | Overexpressing cyclin D 1 in a eukaryotic cell line |
| US6420339B1 (en) | 1998-10-14 | 2002-07-16 | Amgen Inc. | Site-directed dual pegylation of proteins for improved bioactivity and biocompatibility |
| WO2000024418A1 (en) * | 1998-10-27 | 2000-05-04 | Eli Lilly And Company | Prevention of muscle mass loss with leptin receptor ligands |
| ATE323766T1 (de) * | 1999-02-12 | 2006-05-15 | Amgen Inc | Glykosylierte leptinzusammensetzungen und zugehörige verfahren |
| US8106098B2 (en) | 1999-08-09 | 2012-01-31 | The General Hospital Corporation | Protein conjugates with a water-soluble biocompatible, biodegradable polymer |
| JP2005506994A (ja) | 2001-10-22 | 2005-03-10 | アムジェン インコーポレイテッド | ヒト脂肪組織萎縮症を処置するためのレプチンの使用および該処置のための素因決定方法 |
| ATE486842T1 (de) | 2002-03-12 | 2010-11-15 | Merck Sharp & Dohme | Substituierte amide |
| CA2571292C (en) * | 2004-06-30 | 2013-05-21 | Nektar Therapeutics Al, Corporation | Polymer-factor ix moiety conjugates |
| US8394765B2 (en) | 2004-11-01 | 2013-03-12 | Amylin Pharmaceuticals Llc | Methods of treating obesity with two different anti-obesity agents |
| ES2325773T5 (es) | 2004-11-01 | 2014-02-24 | Amylin Pharmaceuticals, Llc. | Tratamiento de la obesidad y de los trastornos relacionados |
| WO2008048691A2 (en) * | 2006-10-18 | 2008-04-24 | Amylin Pharmaceuticals, Inc. | Use of leptin for treating post-lipectomy ectopic fat deposition and other post-lipectomy associated disorders |
| US8501686B2 (en) | 2008-06-05 | 2013-08-06 | University Of Michigan | Method of treating fatty liver diseases and conditions in non-lipodystrophic subjects |
| JP2014502252A (ja) | 2010-09-28 | 2014-01-30 | アミリン・ファーマシューティカルズ，リミテッド・ライアビリティ・カンパニー | 作用持続時間が増した改変ポリペプチド |
| US9968575B2 (en) | 2012-09-27 | 2018-05-15 | The Children's Medical Center Corporation | Compounds for the treatment of obesity and methods of use thereof |
| HRP20190219T1 (hr) | 2013-11-26 | 2019-03-22 | The Children's Medical Center Corporation | Spojevi za tretman pretilosti i postupci za njihovu uporabu |
| US20170209408A1 (en) | 2014-04-03 | 2017-07-27 | The Children's Medical Center Corporation | Hsp90 inhibitors for the treatment of obesity and methods of use thereof |
| PL3509624T3 (pl) | 2016-09-12 | 2024-03-25 | Amryt Pharmaceuticals Inc. | Sposób wykrywania przeciwciał neutralizujących przeciwko leptynie |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1228925B (it) * | 1987-08-07 | 1991-07-10 | Eniricerche Spa | Procedimento per la preparazione dell'ormone della crescita umano |
| DK173142B1 (da) * | 1988-08-24 | 2000-02-07 | Natinco Nv | Fremgangsmåde til forbedring af kødkvaliteten og foderomsætningseffektiviteten for grise |
| US5028440A (en) * | 1990-01-30 | 1991-07-02 | Iowa State University Research Foundation, Inc. | Method of raising meat producing animals to increase lean tissue development |
| KR960703759A (ko) * | 1993-08-13 | 1996-08-31 | 하르트무트 벤케르트 | 대형 물체의 표면 처리공정 및 장치(process and device for treating the surface of large objects) |
| US6309853B1 (en) * | 1994-08-17 | 2001-10-30 | The Rockfeller University | Modulators of body weight, corresponding nucleic acids and proteins, and diagnostic and therapeutic uses thereof |
| GB9511935D0 (en) * | 1995-06-13 | 1995-08-09 | Smithkline Beecham Plc | Novel compound |
| CA2358862A1 (en) * | 1995-11-22 | 1997-05-29 | Amgen Inc. | Methods of increasing lean tissue mass using ob protein compositions |
| RU2178307C2 (ru) * | 1995-12-27 | 2002-01-20 | Джинентех Инк. | Производные ов-протеина |
| CA2275183A1 (en) * | 1996-12-20 | 1998-07-02 | Amgen Inc. | Ob fusion protein compositions and methods |
| CN1202862C (zh) * | 1997-04-17 | 2005-05-25 | 安姆根有限公司 | 包含具有抗体Fc链的稳定、有活性人OB蛋白的结合物的组合物及方法 |
-
1996
- 1996-11-04 CA CA002358862A patent/CA2358862A1/en not_active Abandoned
- 1996-11-04 SI SI9630675T patent/SI0866720T1/xx unknown
- 1996-11-04 NZ NZ511617A patent/NZ511617A/en not_active IP Right Cessation
- 1996-11-04 EP EP02011474A patent/EP1285664B1/en not_active Expired - Lifetime
- 1996-11-04 ES ES02011474T patent/ES2339846T3/es not_active Expired - Lifetime
- 1996-11-04 DE DE69631544T patent/DE69631544T2/de not_active Expired - Lifetime
- 1996-11-04 AT AT02011474T patent/ATE455554T1/de not_active IP Right Cessation
- 1996-11-04 PT PT96938773T patent/PT866720E/pt unknown
- 1996-11-04 EP EP98119160A patent/EP0956862A1/en not_active Withdrawn
- 1996-11-04 AU AU76074/96A patent/AU7607496A/en not_active Abandoned
- 1996-11-04 CA CA002236163A patent/CA2236163A1/en active Pending
- 1996-11-04 EP EP96938773A patent/EP0866720B1/en not_active Expired - Lifetime
- 1996-11-04 IL IL12444296A patent/IL124442A0/xx not_active IP Right Cessation
- 1996-11-04 DE DE69638119T patent/DE69638119D1/de not_active Expired - Lifetime
- 1996-11-04 DK DK96938773T patent/DK0866720T3/da active
- 1996-11-04 WO PCT/US1996/017718 patent/WO1997018833A1/en not_active Ceased
- 1996-11-04 NZ NZ527007A patent/NZ527007A/en not_active IP Right Cessation
- 1996-11-04 JP JP51974597A patent/JP4173914B2/ja not_active Expired - Fee Related
- 1996-11-04 AT AT96938773T patent/ATE259243T1/de active
- 1996-11-04 ES ES96938773T patent/ES2217327T3/es not_active Expired - Lifetime
- 1996-11-04 NZ NZ512083A patent/NZ512083A/xx not_active IP Right Cessation
- 1996-11-15 ZA ZA969605A patent/ZA969605B/xx unknown
-
1998
- 1998-05-20 MX MX9803992A patent/MX9803992A/es not_active IP Right Cessation
-
1999
- 1999-01-05 IL IL127926A patent/IL127926A/en not_active IP Right Cessation
-
2000
- 2000-06-23 AU AU42652/00A patent/AU763755B2/en not_active Ceased
- 2000-06-23 AU AU42653/00A patent/AU763769B2/en not_active Ceased
-
2001
- 2001-11-19 JP JP2001352728A patent/JP4227325B2/ja not_active Expired - Fee Related
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