NZ267567A - Treatment of inflammatory conditions using various indole, benzoquinone and benzofuran derivatives; method of plant material extraction; celery seed extract - Google Patents
Treatment of inflammatory conditions using various indole, benzoquinone and benzofuran derivatives; method of plant material extraction; celery seed extractInfo
- Publication number
- NZ267567A NZ267567A NZ267567A NZ26756794A NZ267567A NZ 267567 A NZ267567 A NZ 267567A NZ 267567 A NZ267567 A NZ 267567A NZ 26756794 A NZ26756794 A NZ 26756794A NZ 267567 A NZ267567 A NZ 267567A
- Authority
- NZ
- New Zealand
- Prior art keywords
- pain
- weeks
- extract
- less
- occur
- Prior art date
Links
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- 229960000258 corticotropin Drugs 0.000 description 1
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- 230000001419 dependent effect Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- XEYBRNLFEZDVAW-ARSRFYASSA-N dinoprostone Chemical compound CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O XEYBRNLFEZDVAW-ARSRFYASSA-N 0.000 description 1
- 229960002986 dinoprostone Drugs 0.000 description 1
- 230000002526 effect on cardiovascular system Effects 0.000 description 1
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- 235000011389 fruit/vegetable juice Nutrition 0.000 description 1
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- 208000016361 genetic disease Diseases 0.000 description 1
- 239000003862 glucocorticoid Substances 0.000 description 1
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- 239000003018 immunosuppressive agent Substances 0.000 description 1
- 229940124589 immunosuppressive drug Drugs 0.000 description 1
- 239000000411 inducer Substances 0.000 description 1
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- 230000008595 infiltration Effects 0.000 description 1
- 238000001764 infiltration Methods 0.000 description 1
- 230000004941 influx Effects 0.000 description 1
- 208000018937 joint inflammation Diseases 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 239000008101 lactose Substances 0.000 description 1
- VNYSSYRCGWBHLG-AMOLWHMGSA-M leukotriene B4(1-) Chemical compound CCCCC\C=C/C[C@@H](O)\C=C\C=C\C=C/[C@@H](O)CCCC([O-])=O VNYSSYRCGWBHLG-AMOLWHMGSA-M 0.000 description 1
- 239000001645 levisticum officinale Substances 0.000 description 1
- SQEHCNOBYLQFTG-UHFFFAOYSA-M lithium;thiophene-2-carboxylate Chemical compound [Li+].[O-]C(=O)C1=CC=CS1 SQEHCNOBYLQFTG-UHFFFAOYSA-M 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 208000019423 liver disease Diseases 0.000 description 1
- 235000009973 maize Nutrition 0.000 description 1
- 230000036210 malignancy Effects 0.000 description 1
- 238000004949 mass spectrometry Methods 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- PSGAAPLEWMOORI-PEINSRQWSA-N medroxyprogesterone acetate Chemical compound C([C@@]12C)CC(=O)C=C1[C@@H](C)C[C@@H]1[C@@H]2CC[C@]2(C)[C@@](OC(C)=O)(C(C)=O)CC[C@H]21 PSGAAPLEWMOORI-PEINSRQWSA-N 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 230000002175 menstrual effect Effects 0.000 description 1
- 229960000485 methotrexate Drugs 0.000 description 1
- 239000013081 microcrystal Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 239000002324 mouth wash Substances 0.000 description 1
- 229940051866 mouthwash Drugs 0.000 description 1
- 210000002346 musculoskeletal system Anatomy 0.000 description 1
- 230000008693 nausea Effects 0.000 description 1
- 201000008383 nephritis Diseases 0.000 description 1
- 230000002981 neuropathic effect Effects 0.000 description 1
- 230000011164 ossification Effects 0.000 description 1
- 230000036961 partial effect Effects 0.000 description 1
- 229960001639 penicillamine Drugs 0.000 description 1
- 230000002085 persistent effect Effects 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 229960002895 phenylbutazone Drugs 0.000 description 1
- VYMDGNCVAMGZFE-UHFFFAOYSA-N phenylbutazonum Chemical compound O=C1C(CCCC)C(=O)N(C=2C=CC=CC=2)N1C1=CC=CC=C1 VYMDGNCVAMGZFE-UHFFFAOYSA-N 0.000 description 1
- BULVZWIRKLYCBC-UHFFFAOYSA-N phorate Chemical compound CCOP(=S)(OCC)SCSCC BULVZWIRKLYCBC-UHFFFAOYSA-N 0.000 description 1
- 150000003904 phospholipids Chemical class 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 230000000750 progressive effect Effects 0.000 description 1
- XEYBRNLFEZDVAW-UHFFFAOYSA-N prostaglandin E2 Natural products CCCCCC(O)C=CC1C(O)CC(=O)C1CC=CCCCC(O)=O XEYBRNLFEZDVAW-UHFFFAOYSA-N 0.000 description 1
- 150000003180 prostaglandins Chemical class 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 230000004144 purine metabolism Effects 0.000 description 1
- 150000003212 purines Chemical class 0.000 description 1
- 238000009790 rate-determining step (RDS) Methods 0.000 description 1
- 230000009103 reabsorption Effects 0.000 description 1
- 230000001739 rebound effect Effects 0.000 description 1
- 238000010992 reflux Methods 0.000 description 1
- 230000008439 repair process Effects 0.000 description 1
- 210000003131 sacroiliac joint Anatomy 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 238000004062 sedimentation Methods 0.000 description 1
- 239000002453 shampoo Substances 0.000 description 1
- 210000003491 skin Anatomy 0.000 description 1
- ACXGJHCPFCFILV-UHFFFAOYSA-M sodium;2-(4-chloro-2-methylphenoxy)acetate;3,6-dichloro-2-methoxybenzoic acid Chemical compound [Na+].COC1=C(Cl)C=CC(Cl)=C1C(O)=O.CC1=CC(Cl)=CC=C1OCC([O-])=O ACXGJHCPFCFILV-UHFFFAOYSA-M 0.000 description 1
- 210000004872 soft tissue Anatomy 0.000 description 1
- 238000004611 spectroscopical analysis Methods 0.000 description 1
- 210000005065 subchondral bone plate Anatomy 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 210000005222 synovial tissue Anatomy 0.000 description 1
- 210000002437 synoviocyte Anatomy 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 201000004415 tendinitis Diseases 0.000 description 1
- 206010043778 thyroiditis Diseases 0.000 description 1
- 230000036962 time dependent Effects 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 238000002054 transplantation Methods 0.000 description 1
- 230000036269 ulceration Effects 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 230000008673 vomiting Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Botany (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Mycology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Compounds Of Unknown Constitution (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AUPL960593 | 1993-06-25 | ||
| PCT/AU1994/000342 WO1995000157A1 (en) | 1993-06-25 | 1994-06-24 | Therapeutic agent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ267567A true NZ267567A (en) | 1997-10-24 |
Family
ID=3777003
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ267567A NZ267567A (en) | 1993-06-25 | 1994-06-24 | Treatment of inflammatory conditions using various indole, benzoquinone and benzofuran derivatives; method of plant material extraction; celery seed extract |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP0708651B1 (https=) |
| JP (1) | JPH09505024A (https=) |
| CN (1) | CN1129908A (https=) |
| AT (1) | ATE185698T1 (https=) |
| CA (1) | CA2165794A1 (https=) |
| DE (1) | DE69421280T2 (https=) |
| ES (1) | ES2140541T3 (https=) |
| IN (1) | IN178310B (https=) |
| NZ (1) | NZ267567A (https=) |
| PL (1) | PL176595B1 (https=) |
| WO (1) | WO1995000157A1 (https=) |
| ZA (1) | ZA944568B (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9821670D0 (en) * | 1998-10-05 | 1998-12-02 | Muhlbauer Roman C | Plant extracts for the treatment of increased bone resorption |
| AUPP797598A0 (en) * | 1998-12-30 | 1999-01-28 | Butters, Desley | Therapeutic agent |
| US6352728B1 (en) * | 1999-11-02 | 2002-03-05 | International Celery Development Alliance Pty. Ltd. | Extracts of celery seed for the prevention and treatment of pain, inflammation and gastrointestinal irritation |
| GB0211943D0 (en) * | 2002-05-23 | 2002-07-03 | Univ Sheffield | Anti-helicobacter activity of celery seed components |
| JP4804353B2 (ja) * | 2003-05-14 | 2011-11-02 | ディーエスエム アイピー アセッツ ビー．ブイ． | 糖尿病の治療及び予防のためのフタリド誘導体の使用 |
| EP1662906A1 (en) | 2003-09-23 | 2006-06-07 | DSM IP Assets B.V. | Compositions for the treatment and prevention of diabetes mellitus |
| CN1257711C (zh) | 2003-12-05 | 2006-05-31 | 石药集团中奇制药技术（石家庄）有限公司 | 丁苯酞软胶囊及其制备工艺 |
| ES2375302T3 (es) * | 2005-05-24 | 2012-02-28 | Dsm Ip Assets B.V. | Derivados de ligustilida para el tratamiento de trastornos inflamatorios. |
| KR20090078777A (ko) * | 2006-08-11 | 2009-07-20 | 디에스엠 아이피 어셋츠 비.브이. | 중추 신경계 질환의 치료를 위한 리구스틸라이드 유도체 |
| CN100569241C (zh) * | 2007-01-17 | 2009-12-16 | 北京天川军威医药技术开发有限公司 | 芹菜籽乙酸乙酯萃取物及其用途 |
| US8722338B2 (en) | 2009-03-11 | 2014-05-13 | The Johns Hopkins University | Modulation of ABCG2-mediated urate transport to treat hyperuricemia and gout |
| AU2010329604B2 (en) * | 2009-11-23 | 2016-05-19 | Bagi Research Limited | Novel therapeutic methods for treating inflammation and immune system disorders |
| JP5581120B2 (ja) * | 2010-06-07 | 2014-08-27 | 花王株式会社 | 電位依存性カチオンチャネル抑制剤 |
| CN102697772A (zh) * | 2012-05-08 | 2012-10-03 | 中国人民解放军第二军医大学 | 一种治疗痛风的药物组合物及其应用 |
| CN103183654B (zh) * | 2013-01-30 | 2014-11-05 | 泰山医学院 | 芹菜籽活性单体的分离纯化制备工艺 |
| CN105535116A (zh) * | 2015-12-23 | 2016-05-04 | 辽宁科技学院 | 一种天然药物提取物及其制备方法 |
| CN110582480B (zh) | 2017-04-21 | 2023-11-10 | 塔斯马尼亚大学 | 治疗化合物和方法 |
| KR20210133463A (ko) * | 2020-04-29 | 2021-11-08 | 한국 한의학 연구원 | 시라 추출물을 유효성분으로 함유하는 골질환의 예방, 개선 또는 치료용 조성물 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2334368A1 (fr) * | 1975-12-10 | 1977-07-08 | Unilever Nv | Procede d'isolation, a partir des pepins de raisin, d'une substance a activite anti-inflammatoire, et composition pour la peau, contenant une telle substance |
| DE3040246C2 (de) * | 1979-10-29 | 1985-01-10 | Osaka Chemical Laboratory Co., Ltd., Osaka | Sojasaponine A↓1↓ und A↓2↓ und ihre Verwendung |
| DE3347658A1 (de) * | 1983-12-31 | 1985-07-11 | Troponwerke GmbH & Co KG, 5000 Köln | 1.4-naphthochinonderivate mit entzuendungshemmender wirkung |
| JPS61257155A (ja) * | 1985-05-10 | 1986-11-14 | Horiuchi:Kk | 抗酸化食品 |
| JPS63501288A (ja) * | 1985-09-20 | 1988-05-19 | ジ・アップジョン・カンパニ− | １，４−ナフタレンジオ−ルおよび１，４−ヒドロキノン誘導体 |
| US4753935A (en) * | 1987-01-30 | 1988-06-28 | Syntex (U.S.A.) Inc. | Morpholinoethylesters of mycophenolic acid and pharmaceutical compositions |
| FR2611502B1 (fr) * | 1987-02-24 | 1990-03-09 | Natura Medica Laboratoires | Extrait de racines d'ombellifere obtenu par extraction hydroalcoolique, procede de preparation d'un tel extrait; et composition therapeutique, notamment a activite diuretique, cardiovasculaire, antalgique ou anti-inflammatoire comprenant un tel extrait |
| JPH02196767A (ja) * | 1988-10-11 | 1990-08-03 | Kyowa Hakko Kogyo Co Ltd | ヒドロキサム酸誘導体 |
| US5102883A (en) * | 1989-10-31 | 1992-04-07 | Du Pont Merck Pharmaceutical Company | Pyrimidine biosynthesis inhibitors useful as immunosuppressive agents |
| IT1242020B (it) * | 1990-11-20 | 1994-02-02 | Sigma Tau Ind Farmaceuti | Ftalidilidene derivati della carnitina e di alcanoil carnitine e composizioni farmaceutiche che li contengono. |
| AU653024B2 (en) * | 1991-05-30 | 1994-09-15 | Novartis Ag | Substituted diaminophthalimides and analogues |
-
1994
- 1994-06-24 IN IN492CA1994 patent/IN178310B/en unknown
- 1994-06-24 WO PCT/AU1994/000342 patent/WO1995000157A1/en not_active Ceased
- 1994-06-24 PL PL94312714A patent/PL176595B1/pl unknown
- 1994-06-24 CA CA002165794A patent/CA2165794A1/en not_active Abandoned
- 1994-06-24 EP EP94918690A patent/EP0708651B1/en not_active Expired - Lifetime
- 1994-06-24 ZA ZA944568A patent/ZA944568B/xx unknown
- 1994-06-24 JP JP6522513A patent/JPH09505024A/ja active Pending
- 1994-06-24 ES ES94918690T patent/ES2140541T3/es not_active Expired - Lifetime
- 1994-06-24 NZ NZ267567A patent/NZ267567A/en unknown
- 1994-06-24 DE DE69421280T patent/DE69421280T2/de not_active Expired - Fee Related
- 1994-06-24 CN CN94193176A patent/CN1129908A/zh active Pending
- 1994-06-24 AT AT94918690T patent/ATE185698T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ZA944568B (en) | 1995-03-20 |
| JPH09505024A (ja) | 1997-05-20 |
| DE69421280T2 (de) | 2000-07-13 |
| IN178310B (https=) | 1997-03-22 |
| PL312714A1 (en) | 1996-05-13 |
| PL176595B1 (pl) | 1999-06-30 |
| EP0708651A1 (en) | 1996-05-01 |
| ATE185698T1 (de) | 1999-11-15 |
| CN1129908A (zh) | 1996-08-28 |
| DE69421280D1 (de) | 1999-11-25 |
| EP0708651A4 (en) | 1998-03-04 |
| WO1995000157A1 (en) | 1995-01-05 |
| CA2165794A1 (en) | 1995-01-05 |
| EP0708651B1 (en) | 1999-10-20 |
| ES2140541T3 (es) | 2000-03-01 |
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