NZ254813A - Liponucleotide derivatives of seco-nucleosides, their preparation and use as anti-viral drugs - Google Patents

Liponucleotide derivatives of seco-nucleosides, their preparation and use as anti-viral drugs

Info

Publication number
NZ254813A
NZ254813A NZ254813A NZ25481393A NZ254813A NZ 254813 A NZ254813 A NZ 254813A NZ 254813 A NZ254813 A NZ 254813A NZ 25481393 A NZ25481393 A NZ 25481393A NZ 254813 A NZ254813 A NZ 254813A
Authority
NZ
New Zealand
Prior art keywords
liponucleotides
group
denotes
formula
substituted
Prior art date
Application number
NZ254813A
Other languages
English (en)
Inventor
Harald Zilch
Dieter Herrmann
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of NZ254813A publication Critical patent/NZ254813A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65616Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • A61P31/22Antivirals for DNA viruses for herpes viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
NZ254813A 1992-08-08 1993-08-06 Liponucleotide derivatives of seco-nucleosides, their preparation and use as anti-viral drugs NZ254813A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4226279A DE4226279A1 (de) 1992-08-08 1992-08-08 Liponucleotide von Seco-Nucleosiden, deren Herstellung sowie deren Verwendung als antivirale Arzneimittel

Publications (1)

Publication Number Publication Date
NZ254813A true NZ254813A (en) 1996-05-28

Family

ID=6465143

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ254813A NZ254813A (en) 1992-08-08 1993-08-06 Liponucleotide derivatives of seco-nucleosides, their preparation and use as anti-viral drugs

Country Status (20)

Country Link
EP (1) EP0654036B1 (cg-RX-API-DMAC7.html)
JP (1) JP3479299B2 (cg-RX-API-DMAC7.html)
KR (1) KR100243440B1 (cg-RX-API-DMAC7.html)
CN (1) CN1040984C (cg-RX-API-DMAC7.html)
AT (1) ATE152114T1 (cg-RX-API-DMAC7.html)
AU (1) AU672994B2 (cg-RX-API-DMAC7.html)
CA (1) CA2141030A1 (cg-RX-API-DMAC7.html)
DE (2) DE4226279A1 (cg-RX-API-DMAC7.html)
DK (1) DK0654036T3 (cg-RX-API-DMAC7.html)
ES (1) ES2104163T3 (cg-RX-API-DMAC7.html)
FI (1) FI109699B (cg-RX-API-DMAC7.html)
GR (1) GR3023960T3 (cg-RX-API-DMAC7.html)
HU (1) HUT72605A (cg-RX-API-DMAC7.html)
IL (1) IL106588A (cg-RX-API-DMAC7.html)
MX (1) MX9304676A (cg-RX-API-DMAC7.html)
NO (1) NO304986B1 (cg-RX-API-DMAC7.html)
NZ (1) NZ254813A (cg-RX-API-DMAC7.html)
TW (1) TW306924B (cg-RX-API-DMAC7.html)
WO (1) WO1994003465A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA935718B (cg-RX-API-DMAC7.html)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5817638A (en) * 1988-07-07 1998-10-06 Nexstar Pharmaceuticals, Inc. Antiviral liponucleosides: treatment of hepatitis B
US6599887B2 (en) 1988-07-07 2003-07-29 Chimerix, Inc. Methods of treating viral infections using antiviral liponucleotides
US6252060B1 (en) 1988-07-07 2001-06-26 Nexstar Pharmaceuticals, Inc. Antiviral liponucleosides: treatment of hepatitis B
DE4402492A1 (de) * 1994-01-28 1995-08-03 Boehringer Mannheim Gmbh Verfahren zur Herstellung von unsymmetrischen Phosphorsäurediestern
US7517858B1 (en) 1995-06-07 2009-04-14 The Regents Of The University Of California Prodrugs of pharmaceuticals with improved bioavailability
KR100389558B1 (ko) * 2000-10-11 2003-06-27 주식회사 한스환경엔지니어링 유리섬유 강화플라스틱 성형품의 표면처리용 직물

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5223263A (en) * 1988-07-07 1993-06-29 Vical, Inc. Liponucleotide-containing liposomes
DE4026265A1 (de) * 1990-08-20 1992-02-27 Boehringer Mannheim Gmbh Neue phospholipid-derivate von nucleosiden, deren herstellung sowie deren verwendung als antivirale arzneimittel

Also Published As

Publication number Publication date
FI950533L (fi) 1995-02-07
EP0654036B1 (de) 1997-04-23
TW306924B (cg-RX-API-DMAC7.html) 1997-06-01
ATE152114T1 (de) 1997-05-15
DK0654036T3 (da) 1997-11-03
ZA935718B (en) 1995-02-06
GR3023960T3 (en) 1997-09-30
AU4708293A (en) 1994-03-03
ES2104163T3 (es) 1997-10-01
IL106588A0 (en) 1993-12-08
DE4226279A1 (de) 1994-02-10
HUT72605A (en) 1996-05-28
JPH08500345A (ja) 1996-01-16
MX9304676A (es) 1994-03-31
CN1085908A (zh) 1994-04-27
HU9500374D0 (en) 1995-03-28
CA2141030A1 (en) 1994-02-09
FI950533A0 (fi) 1995-02-07
JP3479299B2 (ja) 2003-12-15
CN1040984C (zh) 1998-12-02
NO304986B1 (no) 1999-03-15
KR950702998A (ko) 1995-08-23
NO950445D0 (no) 1995-02-07
NO950445L (no) 1995-02-07
IL106588A (en) 1998-01-04
AU672994B2 (en) 1996-10-24
WO1994003465A1 (de) 1994-02-17
KR100243440B1 (ko) 2000-03-02
EP0654036A1 (de) 1995-05-24
DE59306286D1 (de) 1997-05-28
FI109699B (fi) 2002-09-30

Similar Documents

Publication Publication Date Title
AU707196B2 (en) Chemical compounds
US5512671A (en) Ether lipid-nucleoside covalent conjugates
US6767900B2 (en) Phosphonate nucleotide compound
KR100366727B1 (ko) 포스포네이트뉴클레오티드화합물
EP0533825B1 (en) Ether lipid-nucleoside covalent conjugates
IE912930A1 (en) New phospholipid derivatives of nucleosides, processes for the preparation thereof and the use thereof as antiviral medicaments
US6686462B2 (en) Antiviral compounds and methods of administration
KR20000029952A (ko) 포스포네이트뉴클레오티드화합물
US6197775B1 (en) Phosphonate nucleotide derivatives
US6372725B1 (en) Specific lipid conjugates to nucleoside diphosphates and their use as drugs
CN1921867B (zh) 用于治疗hiv感染的膦酸核苷衍生物
NZ254813A (en) Liponucleotide derivatives of seco-nucleosides, their preparation and use as anti-viral drugs
US6080734A (en) Liponucleotides of seco-nucleosides, their production as well as their use as antiviral pharmaceutical agents
CA2165979A1 (en) Liponucleotides of deoxynucleosides, the production thereof and their use as antiviral pharmaceutical agents
HUP0001524A2 (hu) Kovalens foszfolipid-foszfonokarbonsav-konjugátumok és ezeket tartalmazó gyógyszerkészítmények
KR970011307B1 (ko) 누클레오시드의 인지질 유도체
JPWO2001064693A1 (ja) ホスホナートヌクレオチド化合物
JPWO1997000262A1 (ja) ホスホナートヌクレオチド誘導体

Legal Events

Date Code Title Description
ASS Change of ownership

Owner name: HEIDELBERG PHARMA HOLDING GMBH, DE

Free format text: OLD OWNER(S): ROCHE DIAGNOSTICS GMBH

RENW Renewal (renewal fees accepted)