NZ211769A - 9a-aza-9a-homoerythromycin derivatives; antibiotic compositions and intermediates - Google Patents

9a-aza-9a-homoerythromycin derivatives; antibiotic compositions and intermediates

Info

Publication number
NZ211769A
NZ211769A NZ211769A NZ21176985A NZ211769A NZ 211769 A NZ211769 A NZ 211769A NZ 211769 A NZ211769 A NZ 211769A NZ 21176985 A NZ21176985 A NZ 21176985A NZ 211769 A NZ211769 A NZ 211769A
Authority
NZ
New Zealand
Prior art keywords
hydrogen
amino
compound
deoxy
aza
Prior art date
Application number
NZ211769A
Other languages
English (en)
Inventor
J R Hauske
A A Nagel
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/600,252 external-priority patent/US4512982A/en
Application filed by Pfizer filed Critical Pfizer
Publication of NZ211769A publication Critical patent/NZ211769A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NZ211769A 1984-04-13 1985-04-12 9a-aza-9a-homoerythromycin derivatives; antibiotic compositions and intermediates NZ211769A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/600,252 US4512982A (en) 1984-04-13 1984-04-13 9α-Aza-9α-homoerythromycin compounds, pharmaceutical composition and therapeutic method
US06/616,529 US4518590A (en) 1984-04-13 1984-06-04 9α-Aza-9α-homoerythromycin compounds, pharmaceutical compositions and therapeutic method

Publications (1)

Publication Number Publication Date
NZ211769A true NZ211769A (en) 1987-10-30

Family

ID=27083554

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ211769A NZ211769A (en) 1984-04-13 1985-04-12 9a-aza-9a-homoerythromycin derivatives; antibiotic compositions and intermediates

Country Status (19)

Country Link
US (1) US4518590A (en:Method)
EP (1) EP0159856B1 (en:Method)
KR (1) KR860002111B1 (en:Method)
AU (1) AU549235B2 (en:Method)
CA (1) CA1234805A (en:Method)
DE (1) DE3565267D1 (en:Method)
DK (1) DK164785A (en:Method)
EG (1) EG17459A (en:Method)
ES (3) ES8607335A1 (en:Method)
FI (1) FI851449L (en:Method)
GR (1) GR850900B (en:Method)
HU (1) HU195668B (en:Method)
IE (1) IE57739B1 (en:Method)
IL (1) IL74865A (en:Method)
NO (1) NO161497C (en:Method)
NZ (1) NZ211769A (en:Method)
PH (1) PH21185A (en:Method)
PT (1) PT80270B (en:Method)
YU (3) YU62385A (en:Method)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5075289A (en) * 1988-06-07 1991-12-24 Abbott Laboratories 9-r-azacyclic erythromycin antibiotics
US4904644A (en) * 1988-08-03 1990-02-27 Schering Corporation Antimicrobial compound isolated from Actinomadura fulva subsp indica
US5912331A (en) * 1991-03-15 1999-06-15 Merck & Co., Inc. Process for the preparation of 9-deoxo-9(Z)-hydroxyiminoerythromycin A
DE69227713D1 (de) 1991-03-15 1999-01-14 Merck & Co Inc 9-Deoxo-9(Z)-hydroxyiminoerythromycin A und O-Derivate hiervon
US5985844A (en) * 1992-03-26 1999-11-16 Merck & Co., Inc. Homoerythromycin A derivatives modified at the 4"-and 8A-positions
EP0579770B1 (en) * 1991-04-09 1996-06-26 Abbott Laboratories Macrocyclic lactam prokinetic agents
US5189159A (en) * 1992-04-02 1993-02-23 Merck & Co., Inc. 8a-AZA-8a-homoerythromycin cyclic iminoethers
US5523399A (en) * 1991-12-27 1996-06-04 Taisho Pharmaceutical Co., Ltd. 5-O-desosaminylerythronolide derivatives
US5215980A (en) * 1992-01-17 1993-06-01 Merck & Co., Inc. 10-AZA-9-deoxo-11-deoxy-erythromycin A and derivatives thereof
US5210235A (en) * 1992-08-26 1993-05-11 Merck & Co., Inc. Methods of elaborating erythromycin fragments into amine-containing fragments of azalide antibiotics
US5332807A (en) * 1993-04-14 1994-07-26 Merck & Co., Inc. Process of producing 8A- and 9A-azalide antibiotics
DK0699207T3 (da) * 1993-05-19 1997-12-08 Pfizer Mellemprodukt til azithromycin
US5441939A (en) * 1994-03-04 1995-08-15 Pfizer Inc. 3"-desmethoxy derivatives of erythromycin and azithromycin
USRE38426E1 (en) * 1995-10-09 2004-02-10 Aventis Pharma S.A. 5-O-deosaminyl 6-O-methyl erythronolide A derivatives, preparation method therefor and use thereof for preparing biologically active materials
FR2739620B1 (fr) * 1995-10-09 1997-12-19 Roussel Uclaf Nouveaux derives de la 5-0-desosaminyl 6-o-methyl erythronolide a, leur procede de preparation et leur application a la preparation de produits biologiquement actifs
DE60114028T2 (de) 2000-08-23 2006-07-13 Wockhardt Ltd. Verfahren zur herstellung von wasserfreiem azithromycin
MXPA03009786A (es) 2001-04-27 2004-01-29 Pfizer Prod Inc Procedimiento para preparar derivados de 9-desoxo-9a-aza-9a-homoeritromicina a 4"-sustituidos.
EP1483579A4 (en) 2002-02-15 2006-07-12 Merckle Gmbh CONJUGATES OF BIOLOGICALLY ACTIVE COMPOUNDS, METHODS FOR THE PREPARATION AND USE OF CONJUGATES, FORMULATION AND PHARMACEUTICAL APPLICATIONS OBTAINED FROM SUCH CONJUGATES
AU2003219770B2 (en) 2002-02-15 2008-10-09 Merckle Gmbh Conjugates of biologically active compounds, methods for their preparation and use, formulation and pharmaceutical applications thereof
WO2003070254A1 (en) 2002-02-15 2003-08-28 Sympore Gmbh Antibiotic conjugates
GB0310992D0 (en) * 2003-05-13 2003-06-18 Glaxo Group Ltd Novel compounds
US20060116336A1 (en) * 2004-03-17 2006-06-01 American Pharmaceutical Partners, Inc. Lyophilized azithromycin formulation
US7468428B2 (en) * 2004-03-17 2008-12-23 App Pharmaceuticals, Llc Lyophilized azithromycin formulation

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4150220A (en) * 1977-02-04 1979-04-17 Pfizer Inc. Semi-synthetic 4"-erythromycin A derivatives
SE445223B (sv) * 1977-02-04 1986-06-09 Pfizer Sett att framstella 4"-amino-erytomylin-a-derivat
US4180654A (en) * 1978-01-03 1979-12-25 Pfizer Inc. 4"-Deoxy-4"-acylamido derivatives of oleandomycin, erythromycin and erythromycin carbonate
SI7910768A8 (en) * 1979-04-02 1996-06-30 Pliva Pharm & Chem Works Process for pripering 11-aza-4-0-cladinosyl-6-0-desosaminyl-15-ethyl- 7,13,14-trihydroxy-3,5,7,9,12,14-hexamethyl- oxacyclopentadecane-2-one and their derivatives
YU43006B (en) * 1981-03-06 1989-02-28 Pliva Pharm & Chem Works Process for preparing n-methyl-11-aza-10-deoxo-10-dihydro erythromycin and derivatives thereof
US4474768A (en) * 1982-07-19 1984-10-02 Pfizer Inc. N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor
US4465674A (en) * 1983-09-06 1984-08-14 Pfizer Inc. Azahomoerythromycin D derivative and intermediates therefor

Also Published As

Publication number Publication date
ES8705458A1 (es) 1987-05-01
FI851449A7 (fi) 1985-10-14
HUT37629A (en) 1986-01-23
IL74865A0 (en) 1985-07-31
AU549235B2 (en) 1986-01-23
IL74865A (en) 1987-12-31
NO161497C (no) 1989-08-23
ES8607335A1 (es) 1986-06-16
DK164785D0 (da) 1985-04-12
NO851466L (no) 1985-10-14
EP0159856A3 (en) 1986-03-19
ES551503A0 (es) 1987-04-16
US4518590A (en) 1985-05-21
EP0159856A2 (en) 1985-10-30
HU195668B (en) 1988-06-28
DK164785A (da) 1985-12-10
PH21185A (en) 1987-08-12
PT80270A (en) 1985-05-01
AU4107085A (en) 1985-10-17
DE3565267D1 (en) 1988-11-03
YU126887A (en) 1988-02-29
KR850007435A (ko) 1985-12-04
IE57739B1 (en) 1993-03-24
EP0159856B1 (en) 1988-09-28
CA1234805A (en) 1988-04-05
NO161497B (no) 1989-05-16
KR860002111B1 (ko) 1986-11-26
ES551502A0 (es) 1987-05-01
EG17459A (en) 1992-12-30
PT80270B (pt) 1987-10-20
IE850912L (en) 1985-10-13
YU126787A (en) 1988-02-29
FI851449L (fi) 1985-10-14
ES542134A0 (es) 1986-06-16
FI851449A0 (fi) 1985-04-11
GR850900B (en:Method) 1985-11-25
YU62385A (en) 1988-02-29
ES8704965A1 (es) 1987-04-16

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