ATE139697T1 - Macrozyklische laktam-prokinetika - Google Patents

Macrozyklische laktam-prokinetika

Info

Publication number
ATE139697T1
ATE139697T1 AT92911585T AT92911585T ATE139697T1 AT E139697 T1 ATE139697 T1 AT E139697T1 AT 92911585 T AT92911585 T AT 92911585T AT 92911585 T AT92911585 T AT 92911585T AT E139697 T1 ATE139697 T1 AT E139697T1
Authority
AT
Austria
Prior art keywords
image
pct
prokinetics
sec
macrocyclic lactam
Prior art date
Application number
AT92911585T
Other languages
English (en)
Inventor
Leslie A Freiberg
Carla Edwards
Richard J Pariza
Hugh N Nellans
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Application granted granted Critical
Publication of ATE139697T1 publication Critical patent/ATE139697T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/02—Heterocyclic radicals containing only nitrogen as ring hetero atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Polyamides (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cephalosporin Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
AT92911585T 1991-04-09 1992-03-30 Macrozyklische laktam-prokinetika ATE139697T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US68283691A 1991-04-09 1991-04-09

Publications (1)

Publication Number Publication Date
ATE139697T1 true ATE139697T1 (de) 1996-07-15

Family

ID=24741372

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92911585T ATE139697T1 (de) 1991-04-09 1992-03-30 Macrozyklische laktam-prokinetika

Country Status (15)

Country Link
US (1) US5538961A (de)
EP (1) EP0579770B1 (de)
JP (1) JPH06509326A (de)
KR (1) KR100222014B1 (de)
AT (1) ATE139697T1 (de)
AU (1) AU663089B2 (de)
CA (1) CA2103913A1 (de)
DE (1) DE69211845T2 (de)
DK (1) DK0579770T3 (de)
ES (1) ES2091471T3 (de)
GR (1) GR3020853T3 (de)
IE (1) IE73236B1 (de)
IL (1) IL101504A (de)
PT (1) PT100357B (de)
WO (1) WO1992018134A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1122261A3 (de) * 2000-01-31 2001-09-26 Pfizer Products Inc. 13- und 14-Gliederige Antibakterielle-Makroliden
JP2003523347A (ja) 2000-02-18 2003-08-05 コーサン バイオサイエンシーズ， インコーポレイテッド モチライド化合物
ATE321770T1 (de) 2000-08-17 2006-04-15 Kitasato Inst Pseudoerythromycin-derivate
JP2004522726A (ja) * 2000-12-01 2004-07-29 コーサン バイオサイエンシーズ， インコーポレイテッド モチリド化合物
US20020094962A1 (en) * 2000-12-01 2002-07-18 Gary Ashley Motilide compounds
AU2003273254B2 (en) * 2002-08-29 2008-10-30 Bristol-Myers Squibb Company Motilide compounds
WO2004024192A1 (en) * 2002-09-12 2004-03-25 University Of Chicago Monitoring and diagnosis of gastric emptying and gastroparesis
EP2210612B1 (de) 2003-06-18 2016-10-05 Ocera Therapeutics, Inc. Makrozyklische Motilin Rezeptorantagonisten
US7407941B2 (en) * 2003-08-26 2008-08-05 Pfizer, Inc. N-desmethyl-N-substituted-11-deoxyerythromycin compounds
US20050113319A1 (en) * 2003-08-26 2005-05-26 Christopher Carreras 11-Deoxy-6,9-ether erythromycin compounds
US7211568B2 (en) * 2003-12-18 2007-05-01 Kosan Biosciences Incorporated 9-Desoxoerythromycin compounds as prokinetic agents
US7582611B2 (en) 2005-05-24 2009-09-01 Pfizer Inc. Motilide compounds
BRPI0619556A2 (pt) * 2005-12-08 2011-10-04 Pfizer processo para desmetilação de grupo 3' -dimetil amino de compostos eritromicina
EP2054429B1 (de) 2006-09-11 2013-11-06 Tranzyme Pharma, Inc. Makrozyklische motilinrezeptor antagonisten zur behandlung von gastro-intestinaler störungen
MX2009005977A (es) * 2006-12-05 2009-06-17 Pfizer Polimorfos de motilida.
US20080287371A1 (en) * 2007-05-17 2008-11-20 Tranzyme Pharma Inc. Macrocyclic antagonists of the motilin receptor for modulation of the migrating motor complex
BR112014002252A2 (pt) 2011-07-29 2018-04-24 Cambridge Epigenetix Ltd métodos para a detecção de modificação de nucleotídeo
ES2669512T3 (es) 2012-11-30 2018-05-28 Cambridge Epigenetix Limited Agente oxidante para nucleótidos modificados
CN115057794B (zh) * 2022-07-07 2023-11-17 桂林理工大学 一种可见光诱导铈催化氧化酰胺去甲基化的方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4512982A (en) * 1984-04-13 1985-04-23 Pfizer Inc. 9α-Aza-9α-homoerythromycin compounds, pharmaceutical composition and therapeutic method
US4518590A (en) * 1984-04-13 1985-05-21 Pfizer Inc. 9α-Aza-9α-homoerythromycin compounds, pharmaceutical compositions and therapeutic method
DE3689758T2 (de) * 1985-08-31 1994-08-18 Kitasato Inst Erythromycinderivat und Verfahren zu dessen Herstellung.
US5008249A (en) * 1985-08-31 1991-04-16 Kitasato Kenkyusho Therapeutic method of stimulating digestive tract contractile motion in mammals
US5106961A (en) * 1987-05-26 1992-04-21 Eli Lilly And Company Erythromycin ring-contracted derivatives
US4958010A (en) * 1988-02-16 1990-09-18 Bristol-Myers Company Epipodophyllotoxin glucoside lactam derivatives
US4920102A (en) * 1988-04-18 1990-04-24 Eli Lilly And Company Method for treating gastrointestinal disorders
US5202434A (en) * 1991-04-05 1993-04-13 Merck & Co., Inc. 8a-aza-8a-homoerythromycin lactams
US5189159A (en) * 1992-04-02 1993-02-23 Merck & Co., Inc. 8a-AZA-8a-homoerythromycin cyclic iminoethers

Also Published As

Publication number Publication date
EP0579770A1 (de) 1994-01-26
KR100222014B1 (ko) 1999-10-01
IL101504A (en) 1998-04-05
IE73236B1 (en) 1997-05-21
JPH06509326A (ja) 1994-10-20
PT100357B (pt) 1999-06-30
US5538961A (en) 1996-07-23
IL101504A0 (en) 1992-12-30
DE69211845T2 (de) 1997-01-23
AU663089B2 (en) 1995-09-28
PT100357A (pt) 1993-07-30
DE69211845D1 (de) 1996-08-01
AU1910392A (en) 1992-11-17
ES2091471T3 (es) 1996-11-01
WO1992018134A1 (en) 1992-10-29
DK0579770T3 (da) 1996-11-04
IE921045A1 (en) 1992-10-21
CA2103913A1 (en) 1992-10-10
EP0579770A4 (de) 1994-03-30
EP0579770B1 (de) 1996-06-26
GR3020853T3 (en) 1996-11-30

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Legal Events

Date Code Title Description
REN Ceased due to non-payment of the annual fee