PT100357A - Compostos lactama macrociclicos, seu processo de preparacao e intermediarios, e composicoes que os contem - Google Patents

Compostos lactama macrociclicos, seu processo de preparacao e intermediarios, e composicoes que os contem

Info

Publication number
PT100357A
PT100357A PT100357A PT10035792A PT100357A PT 100357 A PT100357 A PT 100357A PT 100357 A PT100357 A PT 100357A PT 10035792 A PT10035792 A PT 10035792A PT 100357 A PT100357 A PT 100357A
Authority
PT
Portugal
Prior art keywords
compounds
compositions
lactama
intermediaries
macrocyclic
Prior art date
Application number
PT100357A
Other languages
English (en)
Other versions
PT100357B (pt
Inventor
Richard J Pariza
Leslie A Freiberg
Carla Edwards
Hugh N Nellans
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of PT100357A publication Critical patent/PT100357A/pt
Publication of PT100357B publication Critical patent/PT100357B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/02—Heterocyclic radicals containing only nitrogen as ring hetero atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Polyamides (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Cephalosporin Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
PT100357A 1991-04-09 1992-04-08 Compostos lactama macrociclicos, seu processo de preparacao e intermediarios, e composicoes que os contem PT100357B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US68283691A 1991-04-09 1991-04-09

Publications (2)

Publication Number Publication Date
PT100357A true PT100357A (pt) 1993-07-30
PT100357B PT100357B (pt) 1999-06-30

Family

ID=24741372

Family Applications (1)

Application Number Title Priority Date Filing Date
PT100357A PT100357B (pt) 1991-04-09 1992-04-08 Compostos lactama macrociclicos, seu processo de preparacao e intermediarios, e composicoes que os contem

Country Status (15)

Country Link
US (1) US5538961A (pt)
EP (1) EP0579770B1 (pt)
JP (1) JPH06509326A (pt)
KR (1) KR100222014B1 (pt)
AT (1) ATE139697T1 (pt)
AU (1) AU663089B2 (pt)
CA (1) CA2103913A1 (pt)
DE (1) DE69211845T2 (pt)
DK (1) DK0579770T3 (pt)
ES (1) ES2091471T3 (pt)
GR (1) GR3020853T3 (pt)
IE (1) IE73236B1 (pt)
IL (1) IL101504A (pt)
PT (1) PT100357B (pt)
WO (1) WO1992018134A1 (pt)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1122261A3 (en) * 2000-01-31 2001-09-26 Pfizer Products Inc. 13 and 14-membered antibacterial macrolides
WO2001060833A2 (en) 2000-02-18 2001-08-23 Kosan Biosciences, Inc. Motilide compounds
EP1489090B1 (en) * 2000-08-17 2006-02-01 The Kitasato Institute Novel pseudoerythormycin derivatives
US20020094962A1 (en) * 2000-12-01 2002-07-18 Gary Ashley Motilide compounds
JP2004522726A (ja) * 2000-12-01 2004-07-29 コーサン バイオサイエンシーズ， インコーポレイテッド モチリド化合物
WO2004019879A2 (en) * 2002-08-29 2004-03-11 Kosan Biosciences, Inc. Motilide compounds
EP1536841A1 (en) * 2002-09-12 2005-06-08 The University of Chicago Monitoring and diagnosis of gastric emptying and gastroparesis
ES2338789T3 (es) 2003-06-18 2010-05-12 Tranzyme Pharma Inc. Antagonistas macrociclicos del receptor de motilina.
US7407941B2 (en) * 2003-08-26 2008-08-05 Pfizer, Inc. N-desmethyl-N-substituted-11-deoxyerythromycin compounds
US20050113319A1 (en) * 2003-08-26 2005-05-26 Christopher Carreras 11-Deoxy-6,9-ether erythromycin compounds
US7211568B2 (en) * 2003-12-18 2007-05-01 Kosan Biosciences Incorporated 9-Desoxoerythromycin compounds as prokinetic agents
US7582611B2 (en) * 2005-05-24 2009-09-01 Pfizer Inc. Motilide compounds
AU2006323175A1 (en) * 2005-12-08 2007-06-14 Pfizer, Inc. Method for demethylating the 3'-dimethylamino group of erythromycin compounds
CN101528765B (zh) 2006-09-11 2015-04-22 欧塞拉治疗有限公司 用于治疗胃肠动力障碍病症的促胃动素受体的大环拮抗剂
BRPI0719565A2 (pt) 2006-12-05 2013-12-10 Pfizer Polimorfos de motilídeo
US20080287371A1 (en) * 2007-05-17 2008-11-20 Tranzyme Pharma Inc. Macrocyclic antagonists of the motilin receptor for modulation of the migrating motor complex
CN103827321B (zh) * 2011-07-29 2017-08-25 剑桥表现遗传学有限公司 用于检测核苷酸修饰的方法
EP3351644B1 (en) 2012-11-30 2020-01-29 Cambridge Epigenetix Limited Oxidising agent for modified nucleotides
CN115057794B (zh) * 2022-07-07 2023-11-17 桂林理工大学 一种可见光诱导铈催化氧化酰胺去甲基化的方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4512982A (en) * 1984-04-13 1985-04-23 Pfizer Inc. 9α-Aza-9α-homoerythromycin compounds, pharmaceutical composition and therapeutic method
US4518590A (en) * 1984-04-13 1985-05-21 Pfizer Inc. 9α-Aza-9α-homoerythromycin compounds, pharmaceutical compositions and therapeutic method
EP0215355B1 (en) * 1985-08-31 1994-04-06 Kitasato Kenkyusho Erythromycin derivative and process for preparing the same
US5008249A (en) * 1985-08-31 1991-04-16 Kitasato Kenkyusho Therapeutic method of stimulating digestive tract contractile motion in mammals
US5106961A (en) * 1987-05-26 1992-04-21 Eli Lilly And Company Erythromycin ring-contracted derivatives
US4958010A (en) * 1988-02-16 1990-09-18 Bristol-Myers Company Epipodophyllotoxin glucoside lactam derivatives
US4920102A (en) * 1988-04-18 1990-04-24 Eli Lilly And Company Method for treating gastrointestinal disorders
US5202434A (en) * 1991-04-05 1993-04-13 Merck & Co., Inc. 8a-aza-8a-homoerythromycin lactams
US5189159A (en) * 1992-04-02 1993-02-23 Merck & Co., Inc. 8a-AZA-8a-homoerythromycin cyclic iminoethers

Also Published As

Publication number Publication date
JPH06509326A (ja) 1994-10-20
ATE139697T1 (de) 1996-07-15
EP0579770A1 (en) 1994-01-26
DK0579770T3 (da) 1996-11-04
CA2103913A1 (en) 1992-10-10
IE921045A1 (en) 1992-10-21
IE73236B1 (en) 1997-05-21
DE69211845T2 (de) 1997-01-23
WO1992018134A1 (en) 1992-10-29
IL101504A0 (en) 1992-12-30
AU663089B2 (en) 1995-09-28
EP0579770A4 (pt) 1994-03-30
IL101504A (en) 1998-04-05
GR3020853T3 (en) 1996-11-30
PT100357B (pt) 1999-06-30
US5538961A (en) 1996-07-23
AU1910392A (en) 1992-11-17
DE69211845D1 (de) 1996-08-01
ES2091471T3 (es) 1996-11-01
KR100222014B1 (ko) 1999-10-01
EP0579770B1 (en) 1996-06-26

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Legal Events

Date Code Title Description
BB1A Laying open of patent application

Effective date: 19930317

FG3A Patent granted, date of granting

Effective date: 19990331

MM3A Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20030930