NO985721L - Polymorfer av donepezilhydroklorid og fremstillingsprosess - Google Patents

Polymorfer av donepezilhydroklorid og fremstillingsprosess

Info

Publication number
NO985721L
NO985721L NO985721A NO985721A NO985721L NO 985721 L NO985721 L NO 985721L NO 985721 A NO985721 A NO 985721A NO 985721 A NO985721 A NO 985721A NO 985721 L NO985721 L NO 985721L
Authority
NO
Norway
Prior art keywords
polymorphs
manufacturing process
donepezil hydrochloride
donepezil
hydrochloride
Prior art date
Application number
NO985721A
Other languages
English (en)
Other versions
NO321267B1 (no
NO985721D0 (no
Inventor
Akio Imai
Hideaki Watanabe
Takashi Kajima
Yasushi Ishihama
Akiyo Ohtsuka
Tomohide Tanaka
Yukio Narabu
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/JP1996/003881 external-priority patent/WO1997046526A1/en
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Publication of NO985721D0 publication Critical patent/NO985721D0/no
Publication of NO985721L publication Critical patent/NO985721L/no
Publication of NO321267B1 publication Critical patent/NO321267B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/30—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
    • C07D211/32—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Psychiatry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO19985721A 1996-06-07 1998-12-07 Polymorfe av donepezilhydroklorid, fremgangsmater for fremstilling derav, anvendelse derav samt terapeutisk preparat inneholdende den samme. NO321267B1 (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP14629396 1996-06-07
PCT/JP1996/003881 WO1997046526A1 (en) 1996-06-07 1996-12-27 Stable polymorphs of donepezil (1-benzyl-4-[(5,6-dimethoxy-1-indanon)-2-yl]methylpiperidine) hydrochloride and process for production
US08/774,802 US6140321A (en) 1996-06-07 1996-12-30 Polymorphs of donepezil hydrochloride and process for production
PCT/JP1997/001932 WO1997046527A1 (en) 1996-06-07 1997-06-06 Polymorphs of donepezil hydrochloride and process for production

Publications (3)

Publication Number Publication Date
NO985721D0 NO985721D0 (no) 1998-12-07
NO985721L true NO985721L (no) 1999-01-28
NO321267B1 NO321267B1 (no) 2006-04-10

Family

ID=27307991

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19985721A NO321267B1 (no) 1996-06-07 1998-12-07 Polymorfe av donepezilhydroklorid, fremgangsmater for fremstilling derav, anvendelse derav samt terapeutisk preparat inneholdende den samme.

Country Status (12)

Country Link
EP (2) EP1019374B1 (no)
AU (1) AU731282B2 (no)
CA (1) CA2252806C (no)
DK (1) DK1019374T3 (no)
ES (1) ES2188946T3 (no)
HK (1) HK1020952A1 (no)
NO (1) NO321267B1 (no)
NZ (1) NZ333197A (no)
RU (1) RU2190603C2 (no)
SI (1) SI9720038B (no)
SK (1) SK285312B6 (no)
WO (1) WO1997046527A1 (no)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE241358T1 (de) 1997-03-03 2003-06-15 Eisai Co Ltd Verwendung von cholinesterasehemmer zur behandlung von konzentrationsstörungen
GB9716879D0 (en) * 1997-08-08 1997-10-15 Shire Int Licensing Bv Treatment of attention deficit disorders
WO1999029668A1 (fr) * 1997-12-05 1999-06-17 Eisai Co., Ltd. Polycristaux de donepezil et leur procede de production
US6193993B1 (en) 1998-03-03 2001-02-27 Eisai Co., Ltd. Suppository containing an antidementia medicament
JP2002518329A (ja) 1998-06-16 2002-06-25 イーライ・リリー・アンド・カンパニー アセチルコリンレベルを増加させる方法
US6288108B1 (en) 1998-06-16 2001-09-11 Eli Lilly And Company Methods for increasing levels of acetylcholine
JP2002518299A (ja) * 1998-06-16 2002-06-25 イーライ・リリー・アンド・カンパニー アセチルコリンレベルを増加させる方法
ES2275670T3 (es) 2000-03-03 2007-06-16 EISAI R&D MANAGEMENT CO., LTD. Metodos novedosos utilizando inhibidores de colinesterasa.
SI21223A (sl) * 2002-06-19 2003-12-31 Krka, Tovarna Zdravil, D.D., Novo Mesto Farmacevtska formulacija s stabiliziranim amorfnim donepezilijevim kloridom
IL150509A (en) 2002-07-01 2007-07-04 Joseph Kaspi Pharmaceutical preparations containing donafazil hydrochloride
WO2004041281A1 (en) * 2002-11-01 2004-05-21 Oregon Health And Science University Treatment of hyperkinetic movement disorder with donepezil
US20050288330A1 (en) * 2004-06-29 2005-12-29 Avinash Naidu Process for producing a polymorphic form of (1-Benzyl-4-[(5,6-dimethoxy-1-indanone)-2-yl] methyl piperidine hydrochloride (donepezil hydrochloride)
US7186842B2 (en) 2003-02-12 2007-03-06 Usv, Ltd. Polymorph of (1-benzyl-4-[(5,6-dimethoxy-1-indanone)-2-y1] methyl piperidine hydrochloride (Donepezil hydrochloride) and a process for producing thereof
AU2003245029A1 (en) * 2003-04-16 2004-11-04 Hetero Drugs Limited Novel crystalline forms of donepezil hydrochloride
EP1771416A1 (en) * 2004-07-28 2007-04-11 USV Limited A novel polymorph of (1-benzyl-4-[(5,6-dimethoxy-1-indanone)-2-yl] methyl piperidine hydrochloride (donepezil hydrochloride) and a process for producing thereof
EP1773339A4 (en) * 2004-07-30 2009-07-29 Reddys Lab Ltd Dr CRYSTALLINE FORM OF DONEPEZIL HYDROCHLORIDE
EP2283811A1 (en) * 2004-10-19 2011-02-16 Krka Tovarna Zdravil, D.D., Novo Mesto Solid pharmaceutical composition comprising donepezil hydrochloride
EP1858847A1 (en) * 2005-02-28 2007-11-28 Ranbaxy Laboratories Limited Stable form i donepezil hydrochloride and process for its preparation and use in pharmaceutical compositions
EP1858848A1 (en) * 2005-03-17 2007-11-28 Synthon B.V. Process for making crystalline donepezil hydrochloride monohydrate
WO2006111983A2 (en) * 2005-04-21 2006-10-26 Jubilant Organosys Limited NOVEL POLYMORPHIC FORM OF (l-BENZYL-4-[(5,6-DIMETHOXY-l- INDANONE)-2-YL]METHYL PIPERIDINE HYDROCHLORIDE AND PROCESS FOR PREPARING THE SAME
GB0515803D0 (en) * 2005-07-30 2005-09-07 Pliva Hrvatska D O O Intermediate compounds
HU227474B1 (en) * 2005-12-20 2011-07-28 Richter Gedeon Nyrt Process for industrial scale production of high purity donepezil hydrochloride polymorph i.
US20100204470A1 (en) 2006-06-27 2010-08-12 Sandoz Ag method for salt preparation
WO2008073452A1 (en) * 2006-12-11 2008-06-19 Reviva Pharmaceuticals, Inc. Compositions, synthesis, and methods of using indanone based cholinesterase inhibitors
DE102007037932A1 (de) 2007-08-11 2009-02-12 Alfred E. Tiefenbacher Gmbh & Co.Kg Donepezilhydrochlorid in amorpher Form enthaltende Tablette
CN102603612A (zh) * 2007-09-28 2012-07-25 天津和美生物技术有限公司 多奈哌齐盐的多晶型物及其制备和应用
WO2010071216A1 (en) * 2008-12-17 2010-06-24 Eisai R&D Management Co., Ltd. Polymorphic crystal of donepezil and process for producing the same
DE102010010998A1 (de) 2010-03-10 2011-09-15 Stada Arzneimittel Ag Feste pharmazeutische Zusammensetzung, umfassend Donepezil-Hydrochlorid der kristallinen polymorphen Form I
WO2011151359A1 (en) 2010-06-02 2011-12-08 Noscira, S.A. Combined treatment with a cholinesterase inhibitor and a thiadiazolidinedione derivative
EP2502620A1 (en) 2011-03-24 2012-09-26 Krka Tovarna Zdravil, D.D., Novo Mesto Solid pharmaceutical composition comprising donepezil
CN110393440B (zh) * 2019-06-28 2021-08-13 顾美红 一种即热式烧水机
WO2024145323A1 (en) 2022-12-28 2024-07-04 Corium, Llc Pre-mixing method of preparing transdermal delivery system
WO2024145319A1 (en) 2022-12-28 2024-07-04 Corium, Llc Method of preparing transdermal delivery system

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI95572C (fi) * 1987-06-22 1996-02-26 Eisai Co Ltd Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi

Also Published As

Publication number Publication date
NO321267B1 (no) 2006-04-10
CA2252806C (en) 2005-11-22
SK167698A3 (en) 1999-06-11
EP1211243A1 (en) 2002-06-05
NZ333197A (en) 2001-03-30
SK285312B6 (sk) 2006-10-05
RU2190603C2 (ru) 2002-10-10
WO1997046527A1 (en) 1997-12-11
SI9720038A (sl) 1999-06-30
HK1020952A1 (en) 2000-05-26
EP1019374B1 (en) 2003-01-02
EP1019374A1 (en) 2000-07-19
ES2188946T3 (es) 2003-07-01
SI9720038B (sl) 2010-06-30
DK1019374T3 (da) 2003-04-07
AU731282B2 (en) 2001-03-29
AU2979297A (en) 1998-01-05
EP1211243B1 (en) 2009-10-14
CA2252806A1 (en) 1997-12-11
NO985721D0 (no) 1998-12-07

Similar Documents

Publication Publication Date Title
NO985721D0 (no) Polymorfer av donepezilhydroklorid og fremstillingsprosess
NO993676D0 (no) Fremgangsmåte for fremstilling og rensing av et N-alkylert aspartamderivat
DK1041879T4 (da) Desinfektionsmiddel og fremstillingsmetode
IS4940A (is) Erýtrómýsín og aðferð við að framleiða þau
DE69607164D1 (de) Schalldämpfungsverfahren und schalldämmelement dafür
NO984161D0 (no) Fremgangsmåte og innretning for fremstilling av etalisk jern
DK0832565T3 (da) Mælkeerstatningsprodukt og fremgangsmåde til fremstilling deraf
DE69531617D1 (de) Polymere mikrokugen und herstellungsverfahren
NO981826D0 (no) Filterelement og fremgangsmÕte for fremstilling
NO20000695D0 (no) Fiberstruktur og fremgangsmÕte for fremstilling derav
NO974500D0 (no) Blandinger og fremgangsmåter for inhibering av trombogenese
NO951369L (no) Rörenhet og fremgangsmåte ved fremstilling av denne
NO991382L (no) Mellomprodukter og fremgangsmÕte for fremstilling av olanzapin
NO20012963L (no) Fremgangsmåte for fremstilling av 3-alkanoylindoler og 3- alkylindoler
IS3792A7 (is) Benzodiazepinones og aðferð til framleiðslu þess
EG21755A (en) Process for preparing of lercanidipine hydrochloride and their use for the treatment of angina and coronary disease
DK0866658T3 (da) Mejeriprodukt og fremgangsmåde til fremstilling deraf
NO963393D0 (no) Börste og fremgangsmåte ved dens fremstilling
DK0891938T3 (da) Maskine og fremgangsmåde til stabling
DE69730605D1 (de) Dragier-produkte und herstellungsverfahren
NO974826D0 (no) Fremgangsmåte for fremstilling av racemisk og enantiomert 1-(pyridyl)-2-cykloheksyletylamin
NO20001827D0 (no) Stator og fremgangsmåte for fremstilling av en stator
NO20012099L (no) Fremgangsmåte for fremstilling av 4-arylpiperidin-3- karbinoler og beslektede forbindelser
NO990018D0 (no) Belegg og fremgangsmÕte for fremstilling derav
DE69529986D1 (de) Deaminoneuraminidase und herstellungsverfahren dafür

Legal Events

Date Code Title Description
MK1K Patent expired