NO985721D0 - Polymorfer av donepezilhydroklorid og fremstillingsprosess - Google Patents
Polymorfer av donepezilhydroklorid og fremstillingsprosessInfo
- Publication number
- NO985721D0 NO985721D0 NO985721A NO985721A NO985721D0 NO 985721 D0 NO985721 D0 NO 985721D0 NO 985721 A NO985721 A NO 985721A NO 985721 A NO985721 A NO 985721A NO 985721 D0 NO985721 D0 NO 985721D0
- Authority
- NO
- Norway
- Prior art keywords
- polymorphs
- manufacturing process
- donepezil hydrochloride
- donepezil
- hydrochloride
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/30—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
- C07D211/32—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom by oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP14629396 | 1996-06-07 | ||
PCT/JP1996/003881 WO1997046526A1 (en) | 1996-06-07 | 1996-12-27 | Stable polymorphs of donepezil (1-benzyl-4-[(5,6-dimethoxy-1-indanon)-2-yl]methylpiperidine) hydrochloride and process for production |
US08/774,802 US6140321A (en) | 1996-06-07 | 1996-12-30 | Polymorphs of donepezil hydrochloride and process for production |
PCT/JP1997/001932 WO1997046527A1 (en) | 1996-06-07 | 1997-06-06 | Polymorphs of donepezil hydrochloride and process for production |
Publications (3)
Publication Number | Publication Date |
---|---|
NO985721D0 true NO985721D0 (no) | 1998-12-07 |
NO985721L NO985721L (no) | 1999-01-28 |
NO321267B1 NO321267B1 (no) | 2006-04-10 |
Family
ID=27307991
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO19985721A NO321267B1 (no) | 1996-06-07 | 1998-12-07 | Polymorfe av donepezilhydroklorid, fremgangsmater for fremstilling derav, anvendelse derav samt terapeutisk preparat inneholdende den samme. |
Country Status (12)
Country | Link |
---|---|
EP (2) | EP1019374B1 (no) |
AU (1) | AU731282B2 (no) |
CA (1) | CA2252806C (no) |
DK (1) | DK1019374T3 (no) |
ES (1) | ES2188946T3 (no) |
HK (1) | HK1020952A1 (no) |
NO (1) | NO321267B1 (no) |
NZ (1) | NZ333197A (no) |
RU (1) | RU2190603C2 (no) |
SI (1) | SI9720038B (no) |
SK (1) | SK285312B6 (no) |
WO (1) | WO1997046527A1 (no) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2282654C (en) * | 1997-03-03 | 2009-02-03 | Eisai Co., Ltd. | Use of cholinesterase inhibitors to treat attention deficit hyperactivity disorder |
GB9716879D0 (en) * | 1997-08-08 | 1997-10-15 | Shire Int Licensing Bv | Treatment of attention deficit disorders |
ATE260896T1 (de) | 1997-12-05 | 2004-03-15 | Eisai Co Ltd | Donepezil polykristalle und verfharen zu ihrer herstellung |
US6193993B1 (en) | 1998-03-03 | 2001-02-27 | Eisai Co., Ltd. | Suppository containing an antidementia medicament |
SK18812000A3 (sk) * | 1998-06-16 | 2002-01-07 | Eli Lilly And Company | Spôsoby zvyšovania hladín acetylcholínu |
US6288108B1 (en) | 1998-06-16 | 2001-09-11 | Eli Lilly And Company | Methods for increasing levels of acetylcholine |
CN1305377A (zh) * | 1998-06-16 | 2001-07-25 | 伊莱利利公司 | 提高乙酰胆碱水平的方法 |
JP2003525903A (ja) | 2000-03-03 | 2003-09-02 | エーザイ株式会社 | コリンエステラーゼ阻害剤の新規使用法 |
SI21223A (sl) * | 2002-06-19 | 2003-12-31 | Krka, Tovarna Zdravil, D.D., Novo Mesto | Farmacevtska formulacija s stabiliziranim amorfnim donepezilijevim kloridom |
IL150509A (en) | 2002-07-01 | 2007-07-04 | Joseph Kaspi | Pharmaceutical preparations containing donafazil hydrochloride |
WO2004041281A1 (en) * | 2002-11-01 | 2004-05-21 | Oregon Health And Science University | Treatment of hyperkinetic movement disorder with donepezil |
WO2006011154A1 (en) * | 2004-07-28 | 2006-02-02 | Usv Limited | A novel polymorph of (1-benzyl-4-[(5,6-dimethoxy-1-indanone)-2-yl] methyl piperidine hydrochloride (donepezil hydrochloride) and a process for producing thereof |
US7186842B2 (en) | 2003-02-12 | 2007-03-06 | Usv, Ltd. | Polymorph of (1-benzyl-4-[(5,6-dimethoxy-1-indanone)-2-y1] methyl piperidine hydrochloride (Donepezil hydrochloride) and a process for producing thereof |
US20050288330A1 (en) * | 2004-06-29 | 2005-12-29 | Avinash Naidu | Process for producing a polymorphic form of (1-Benzyl-4-[(5,6-dimethoxy-1-indanone)-2-yl] methyl piperidine hydrochloride (donepezil hydrochloride) |
AU2003245029A1 (en) * | 2003-04-16 | 2004-11-04 | Hetero Drugs Limited | Novel crystalline forms of donepezil hydrochloride |
WO2006015338A2 (en) * | 2004-07-30 | 2006-02-09 | Dr. Reddy's Laboratories Ltd. | Crystalline form of donepezil hydrochloride |
DK1811957T3 (da) * | 2004-10-19 | 2009-03-30 | Krka Tovarna Zdravil D D Novo | Fast farmaceutisk sammensætning omfattende donepezilhydrochlorid |
WO2006090263A1 (en) * | 2005-02-28 | 2006-08-31 | Ranbaxy Laboratories Limited | Stable form i donepezil hydrochloride and process for its preparation and use in pharmaceutical compositions |
WO2006097341A1 (en) * | 2005-03-17 | 2006-09-21 | Synthon B.V. | Process for making crystalline donepezil hydrochloride monohydrate |
WO2006111983A2 (en) * | 2005-04-21 | 2006-10-26 | Jubilant Organosys Limited | NOVEL POLYMORPHIC FORM OF (l-BENZYL-4-[(5,6-DIMETHOXY-l- INDANONE)-2-YL]METHYL PIPERIDINE HYDROCHLORIDE AND PROCESS FOR PREPARING THE SAME |
GB0515803D0 (en) * | 2005-07-30 | 2005-09-07 | Pliva Hrvatska D O O | Intermediate compounds |
HU227474B1 (en) * | 2005-12-20 | 2011-07-28 | Richter Gedeon Nyrt | Process for industrial scale production of high purity donepezil hydrochloride polymorph i. |
EP2436381A1 (en) | 2006-06-27 | 2012-04-04 | Sandoz AG | Crystallization of hydrohalides of pharmaceutical compounds |
BRPI0720211A2 (pt) | 2006-12-11 | 2013-12-24 | Reviva Pharmaceuticals Inc | Derivado de indanona, composição, e, uso de uma composição |
DE102007037932A1 (de) | 2007-08-11 | 2009-02-12 | Alfred E. Tiefenbacher Gmbh & Co.Kg | Donepezilhydrochlorid in amorpher Form enthaltende Tablette |
WO2009049479A1 (fr) * | 2007-09-28 | 2009-04-23 | Tianjin Hemay Bio-Tech Co., Ltd. | Polymorphes de sels de donepezil, leurs procédés de préparation et leurs utilisations |
JP5562337B2 (ja) * | 2008-12-17 | 2014-07-30 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | ドネペジルの多形結晶及びその製造方法 |
DE102010010998A1 (de) | 2010-03-10 | 2011-09-15 | Stada Arzneimittel Ag | Feste pharmazeutische Zusammensetzung, umfassend Donepezil-Hydrochlorid der kristallinen polymorphen Form I |
WO2011151359A1 (en) | 2010-06-02 | 2011-12-08 | Noscira, S.A. | Combined treatment with a cholinesterase inhibitor and a thiadiazolidinedione derivative |
EP2502620A1 (en) | 2011-03-24 | 2012-09-26 | Krka Tovarna Zdravil, D.D., Novo Mesto | Solid pharmaceutical composition comprising donepezil |
CN110393440B (zh) * | 2019-06-28 | 2021-08-13 | 顾美红 | 一种即热式烧水机 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FI95572C (fi) * | 1987-06-22 | 1996-02-26 | Eisai Co Ltd | Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi |
-
1997
- 1997-06-06 WO PCT/JP1997/001932 patent/WO1997046527A1/en not_active Application Discontinuation
- 1997-06-06 SI SI9720038A patent/SI9720038B/sl active Search and Examination
- 1997-06-06 EP EP97924337A patent/EP1019374B1/en not_active Expired - Lifetime
- 1997-06-06 DK DK97924337T patent/DK1019374T3/da active
- 1997-06-06 NZ NZ333197A patent/NZ333197A/en not_active IP Right Cessation
- 1997-06-06 SK SK1676-98A patent/SK285312B6/sk not_active IP Right Cessation
- 1997-06-06 RU RU99100325/04A patent/RU2190603C2/ru active
- 1997-06-06 CA CA002252806A patent/CA2252806C/en not_active Expired - Lifetime
- 1997-06-06 EP EP02005248A patent/EP1211243B1/en not_active Expired - Lifetime
- 1997-06-06 ES ES97924337T patent/ES2188946T3/es not_active Expired - Lifetime
- 1997-06-06 AU AU29792/97A patent/AU731282B2/en not_active Expired
-
1998
- 1998-12-07 NO NO19985721A patent/NO321267B1/no not_active IP Right Cessation
-
1999
- 1999-12-24 HK HK99106107A patent/HK1020952A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
WO1997046527A1 (en) | 1997-12-11 |
CA2252806A1 (en) | 1997-12-11 |
ES2188946T3 (es) | 2003-07-01 |
HK1020952A1 (en) | 2000-05-26 |
DK1019374T3 (da) | 2003-04-07 |
CA2252806C (en) | 2005-11-22 |
SK167698A3 (en) | 1999-06-11 |
AU2979297A (en) | 1998-01-05 |
RU2190603C2 (ru) | 2002-10-10 |
EP1019374A1 (en) | 2000-07-19 |
SK285312B6 (sk) | 2006-10-05 |
EP1211243A1 (en) | 2002-06-05 |
NO985721L (no) | 1999-01-28 |
NZ333197A (en) | 2001-03-30 |
SI9720038A (sl) | 1999-06-30 |
EP1019374B1 (en) | 2003-01-02 |
EP1211243B1 (en) | 2009-10-14 |
SI9720038B (sl) | 2010-06-30 |
NO321267B1 (no) | 2006-04-10 |
AU731282B2 (en) | 2001-03-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MK1K | Patent expired |