NO983525L - Dihydrobenzofuran og relaterte forbindelser anvendelig som anti-inflammatoriske midler - Google Patents

Dihydrobenzofuran og relaterte forbindelser anvendelig som anti-inflammatoriske midler

Info

Publication number
NO983525L
NO983525L NO983525A NO983525A NO983525L NO 983525 L NO983525 L NO 983525L NO 983525 A NO983525 A NO 983525A NO 983525 A NO983525 A NO 983525A NO 983525 L NO983525 L NO 983525L
Authority
NO
Norway
Prior art keywords
atoms
dihydrobenzofuran
branched
inflammatory agents
straight
Prior art date
Application number
NO983525A
Other languages
English (en)
Norwegian (no)
Other versions
NO983525D0 (no
Inventor
Michael Wiard Scherz
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of NO983525D0 publication Critical patent/NO983525D0/no
Publication of NO983525L publication Critical patent/NO983525L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO983525A 1996-02-01 1998-07-31 Dihydrobenzofuran og relaterte forbindelser anvendelig som anti-inflammatoriske midler NO983525L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/595,158 US5684041A (en) 1996-02-01 1996-02-01 Dihydrobenzofuran and related compounds useful as anti-inflammatory agents
PCT/US1997/001308 WO1997028143A1 (fr) 1996-02-01 1997-01-30 Composes de dihydrobenzofurane utilises comme agents anti-inflammatoires

Publications (2)

Publication Number Publication Date
NO983525D0 NO983525D0 (no) 1998-07-31
NO983525L true NO983525L (no) 1998-09-30

Family

ID=24381988

Family Applications (1)

Application Number Title Priority Date Filing Date
NO983525A NO983525L (no) 1996-02-01 1998-07-31 Dihydrobenzofuran og relaterte forbindelser anvendelig som anti-inflammatoriske midler

Country Status (16)

Country Link
US (1) US5684041A (fr)
EP (1) EP0879231B1 (fr)
JP (1) JP3095421B2 (fr)
KR (1) KR100350920B1 (fr)
CN (1) CN1097588C (fr)
AT (1) ATE277031T1 (fr)
AU (1) AU730319B2 (fr)
BR (1) BR9707250A (fr)
CA (1) CA2244194C (fr)
DE (1) DE69730817T2 (fr)
DK (1) DK0879231T3 (fr)
ES (1) ES2229331T3 (fr)
MX (1) MX9806251A (fr)
NO (1) NO983525L (fr)
NZ (1) NZ331618A (fr)
WO (1) WO1997028143A1 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0516948U (ja) * 1991-08-16 1993-03-02 湯浅起市郎 金属製板体の吊子構造
ATE445838T1 (de) 2001-07-25 2009-10-15 Raptor Pharmaceutical Inc Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
NZ544298A (en) 2003-06-26 2009-04-30 Takeda Pharmaceutical Cannabinoid receptor modulators including benzofuran derivatives
GB0322016D0 (en) * 2003-09-19 2003-10-22 Merck Sharp & Dohme New compounds
US7435837B2 (en) * 2003-10-24 2008-10-14 Wyeth Dihydrobenzofuranyl alkanamine derivatives and methods for using same
US20050261347A1 (en) * 2003-10-24 2005-11-24 Wyeth Dihydrobenzofuranyl alkanamine derivatives and methods for using same
EP2671508B1 (fr) 2005-04-28 2020-09-16 Proteus Digital Health, Inc. Système pharma-informatique
CA2663377A1 (fr) 2006-09-18 2008-03-27 Raptor Pharmaceutical Inc. Traitement des troubles hepatiques par l'administration de conjugues de proteine associee au recepteur (rap)
HUE059078T2 (hu) 2009-02-20 2022-10-28 Enhanx Biopharm Inc Glutation-alapú hatóanyagszállító rendszer
JP2012526144A (ja) 2009-05-06 2012-10-25 ラボラトリー スキン ケア インコーポレイテッド 活性物質−リン酸カルシウム粒子複合体を含む経皮送達組成物およびその使用方法
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
US11311528B2 (en) 2018-03-20 2022-04-26 Merck Sharp & Dohme Corp. Oxo-tetrahydro-isoquinoline carboxylic acids as STING inhibitors

Family Cites Families (23)

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Publication number Priority date Publication date Assignee Title
US3252999A (en) * 1963-11-01 1966-05-24 American Home Prod Derivatives of 5-amino-2, 3-dihydro-2-methyl benzofuran
US3963717A (en) * 1975-03-10 1976-06-15 Sandoz, Inc. Tricyclic furo-quinazolinones
JPS6019305B2 (ja) * 1976-07-02 1985-05-15 ウェルファイド株式会社 ジヒドロベンゾフラン誘導体
CH632268A5 (de) * 1977-01-14 1982-09-30 Sandoz Ag Verfahren zur herstellung von neuen heterocyclylaminoderivaten.
IT1093805B (it) * 1978-01-31 1985-07-26 Erba Carlo Spa Derivati del 2h-benzofuran-3-one e procedimento per la loro preparazione
US4470440A (en) * 1982-09-30 1984-09-11 Thor Harry A Impact producing tool
JPS60108846A (ja) * 1983-11-18 1985-06-14 Konishiroku Photo Ind Co Ltd ハロゲン化銀写真感光材料
AU556949B2 (en) * 1984-10-25 1986-11-27 Fmc Corporation Pyrozoline insecticides
US4767779A (en) * 1985-09-24 1988-08-30 Fmc Corporation Pyrazoline-1-carboxamides, composition containing them, and insecticidal method of using them
IT206464Z2 (it) * 1986-02-27 1987-08-10 Alfa Romeo Spa Impianto di scarico per un motore a c.i..
DE3777366D1 (de) * 1986-12-27 1992-04-16 Takeda Chemical Industries Ltd 2,3-dihydro-cumaron-derivate, ihre herstellung und verwendung.
US4849428A (en) * 1987-11-23 1989-07-18 The Procter & Gamble Company Cyclic anti-inflammatory derivatives of di-tert-butylphenol compounds, compositions and use
DE3810080A1 (de) * 1988-03-25 1989-10-05 Bayer Ag Trisubstituierte 1,3,5-triazin-2,4,6-trione
JP2855341B2 (ja) * 1988-06-10 1999-02-10 武田薬品工業株式会社 新規2―置換クマラン誘導体
US4966907A (en) * 1988-08-12 1990-10-30 Merck & Co., Inc. 6-substituted 5-hydroxy-2,3-dihydrobenzofurans as inhibitors of leukotriene biosynthesis
US4975457A (en) * 1989-09-25 1990-12-04 Merck & Co., Inc. Trans 2,3-disubstituted-2,3-dihydro-5-hydroxy-benzofurans as inhibitors of leukotriene biosynthesis
WO1991007396A1 (fr) * 1989-11-17 1991-05-30 Meiji Milk Products Co., Ltd. Derive de benzofurane, procede de preparation de ce derive et produit pharmaceutique contenant ce derive comme ingredient actif
US5091533A (en) * 1990-03-12 1992-02-25 Merck Frosst Canada, Inc. 5-hydroxy-2,3-dihydrobenzofuran analogs as leukotriene biosynthesis inhibitors
CA2078126A1 (fr) * 1990-03-27 1991-09-28 Jerry Leroy Adams Inhibiteurs de la 5-lipoxygenase
EP0632031B1 (fr) * 1990-12-28 2000-05-03 Teijin Limited Compose cyclique condense de benzoxa, son procede de production, et composition pharmaceutique le contenant
AU2390892A (en) * 1991-08-08 1993-03-02 Yamanouchi Pharmaceutical Co., Ltd. Urea derivative
FR2682381B1 (fr) * 1991-10-10 1995-04-07 Rhone Poulenc Rorer Sa Derives de benzodiazepine, leur preparation et les medicaments les contenant.
US5684002A (en) * 1994-09-07 1997-11-04 The Procter & Gamble Company Dihydorbenzofuran and related compounds useful as anti-inflammatory agents

Also Published As

Publication number Publication date
WO1997028143A1 (fr) 1997-08-07
CN1210529A (zh) 1999-03-10
US5684041A (en) 1997-11-04
MX9806251A (es) 1998-11-30
DE69730817T2 (de) 2005-02-03
EP0879231B1 (fr) 2004-09-22
EP0879231A1 (fr) 1998-11-25
ES2229331T3 (es) 2005-04-16
CN1097588C (zh) 2003-01-01
KR100350920B1 (ko) 2002-11-18
CA2244194C (fr) 2003-05-06
AU730319B2 (en) 2001-03-01
CA2244194A1 (fr) 1997-08-07
DK0879231T3 (da) 2004-12-20
BR9707250A (pt) 1999-04-06
NZ331618A (en) 2000-08-25
KR19990082223A (ko) 1999-11-25
ATE277031T1 (de) 2004-10-15
AU1842897A (en) 1997-08-22
JPH11503467A (ja) 1999-03-26
JP3095421B2 (ja) 2000-10-03
DE69730817D1 (de) 2004-10-28
NO983525D0 (no) 1998-07-31

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