NO981282L - Calcitriolderivater og deres anvendelser - Google Patents
Calcitriolderivater og deres anvendelserInfo
- Publication number
- NO981282L NO981282L NO981282A NO981282A NO981282L NO 981282 L NO981282 L NO 981282L NO 981282 A NO981282 A NO 981282A NO 981282 A NO981282 A NO 981282A NO 981282 L NO981282 L NO 981282L
- Authority
- NO
- Norway
- Prior art keywords
- compounds
- vitamin
- modified
- calcitriol
- modified compound
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
Abstract
En fremgangsmåte for å behandle metaboliske sykdommer slik som osteoporose, samt andre sykdomstilstander som kan behandles med vitamin D- forbindelser, omfatter å administrere en effektiv mengde av en eller flere modifiserte vitamin D- forbindelser. Den modifiserte forbindelsen inneholder en typisk vitamin D-kjerne, men med in vivo hydrolyserbare grupper på en eller flere posisjoner l, 3 og 25 karbonene. Tiden for kon- versjon av den modifiserte forbindelsen til sin aktive form, slik som calcitriol, kan bli regulert for dermed å fremskaffe kontollert frigivelse av forbindelser in vivo over tid, ved å endre eller modifisere de hydrolyserbare gruppene.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US53186795A | 1995-09-21 | 1995-09-21 | |
US08/531,403 US5952317A (en) | 1995-09-21 | 1995-09-21 | Calcitriol derivatives and their uses |
PCT/US1996/015184 WO1997011053A1 (en) | 1995-09-21 | 1996-09-20 | Calcitriol derivatives and their uses |
Publications (2)
Publication Number | Publication Date |
---|---|
NO981282D0 NO981282D0 (no) | 1998-03-20 |
NO981282L true NO981282L (no) | 1998-05-22 |
Family
ID=27063537
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO981282A NO981282L (no) | 1995-09-21 | 1998-03-20 | Calcitriolderivater og deres anvendelser |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP1021401A1 (no) |
JP (1) | JP3372259B2 (no) |
KR (1) | KR100327922B1 (no) |
AU (1) | AU717238B2 (no) |
CA (1) | CA2229316C (no) |
HU (1) | HUP9802303A3 (no) |
NO (1) | NO981282L (no) |
NZ (2) | NZ501318A (no) |
WO (1) | WO1997011053A1 (no) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU5305600A (en) * | 1999-08-17 | 2001-03-13 | Wisconsin Alumni Research Foundation | Animal feed containing hydrolyzable calcitriol derivatives |
KR100317935B1 (ko) * | 1999-10-20 | 2001-12-22 | 유승필 | 대사성 골질환 치료용 약제조성물 및 이의 제조방법 |
US20020045606A1 (en) | 1999-12-02 | 2002-04-18 | Reddy Satyanarayana G. | Esters of vitamin D3 and uses thereof |
US20030195175A1 (en) * | 2002-03-25 | 2003-10-16 | Deluca Hector F. | Use of carbon-2-modified-vitamin D analogs to induce the formation of new bone |
JP2007525533A (ja) | 2004-03-01 | 2007-09-06 | ビオエクセル エスピーエー | 間質性膀胱炎の治療方法、並びに関連化合物及び組成物 |
US20080293647A1 (en) | 2004-11-12 | 2008-11-27 | Luciano Adorini | Combined Use Of Vitamin D Derivatives And Anti-Proliferative Agents For Treating Bladder Cancer |
HUE029572T2 (en) | 2006-02-03 | 2017-03-28 | Opko Renal Llc | Treatment of Vitamin D Insufficiency and Deficiency with 25-Hydroxy-D2 and 25-Hydroxy-D3 |
US8329677B2 (en) | 2006-06-21 | 2012-12-11 | Cytochroma, Inc. | Method of treating and preventing secondary hyperparathyroidism |
EP3542792B1 (en) | 2007-04-25 | 2023-06-28 | EirGen Pharma Ltd. | Controlled release 25-hydroxyvitamin d |
WO2008134518A2 (en) | 2007-04-25 | 2008-11-06 | Cytochroma Inc. | Methods and compounds for vitamin d therapy |
KR101495578B1 (ko) | 2007-04-25 | 2015-02-25 | 사이토크로마 인코포레이티드 | 비타민 d 부족 및 결핍의 치료 방법 |
WO2008134523A1 (en) | 2007-04-25 | 2008-11-06 | Proventiv Therapeutics, Llc | Method of safely and effectively treating and preventing secondary hyperparathyroidism in chronic kidney disease |
KR101852042B1 (ko) | 2008-04-02 | 2018-04-25 | 사이토크로마 인코포레이티드 | 비타민 d 결핍 및 관련 장애에 유용한 방법, 조성물, 용도 및 키트 |
LT2552484T (lt) | 2010-03-29 | 2020-04-27 | Opko Ireland Global Holdings, Ltd. | Būdai ir kompozicijos, skirti paratiroidų lygiams sumažinti |
KR101847947B1 (ko) | 2013-03-15 | 2018-05-28 | 옵코 아이피 홀딩스 Ⅱ 인코포레이티드 | 안정화되고 변형된 비타민 d 방출 제형 |
CN114681468A (zh) | 2014-08-07 | 2022-07-01 | 欧普科爱尔兰环球控股有限公司 | 利用25-羟基维生素d的辅助疗法 |
TW202214257A (zh) | 2016-03-28 | 2022-04-16 | 愛爾蘭商歐科愛爾蘭全球控股股份有限公司 | 維生素d治療之方法 |
KR101983654B1 (ko) * | 2018-07-24 | 2019-05-29 | 한국과학기술원 | Cfc 증후군 환자의 발달 저해를 완화할 수 있는 치료용 조성물 |
CN114656413B (zh) * | 2022-03-30 | 2024-04-09 | 南通华山药业有限公司 | 一种阿法骨化醇杂环酯类衍生物及其制备方法 |
CN114681467B (zh) * | 2022-03-30 | 2024-03-12 | 南通华山药业有限公司 | 一种阿法骨化醇杂环酯类衍生物在制备抗肿瘤药物中的应用 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4195027A (en) * | 1978-01-16 | 1980-03-25 | Wisconsin Alumni Research Foundation | Process for preparing 1α-hydroxylated compounds |
US4206131A (en) * | 1978-06-19 | 1980-06-03 | The Upjohn Company | Compounds and process |
US4188345A (en) * | 1978-07-26 | 1980-02-12 | Wisconsin Alumni Research Foundation | Fluorovitamin D compounds and processes for their preparation |
JPS5846508A (ja) * | 1981-09-14 | 1983-03-18 | 日本石油化学株式会社 | 導電性材料の製法 |
FR2530624B1 (fr) * | 1982-07-26 | 1987-08-07 | Wisconsin Alumni Res Found | Nouveaux analogues de la vitamine d et compositions pharmaceutiques ou veterinaires les contenant |
JPH0825993B2 (ja) * | 1990-08-20 | 1996-03-13 | 大同ほくさん株式会社 | ビタミンd2およびd3又は活性型ビタミンd2およびd3の製造方法,並びにその中間体 |
JPH05339230A (ja) * | 1992-03-12 | 1993-12-21 | Nisshin Flour Milling Co Ltd | 活性型ビタミンd2及びその誘導体の製造法 |
JP3182215B2 (ja) * | 1992-06-26 | 2001-07-03 | 日清製粉株式会社 | 1−アシルオキシビタミンd誘導体 |
-
1996
- 1996-09-20 AU AU72426/96A patent/AU717238B2/en not_active Ceased
- 1996-09-20 CA CA002229316A patent/CA2229316C/en not_active Expired - Fee Related
- 1996-09-20 NZ NZ501318A patent/NZ501318A/en unknown
- 1996-09-20 NZ NZ319819A patent/NZ319819A/en unknown
- 1996-09-20 EP EP96933853A patent/EP1021401A1/en not_active Withdrawn
- 1996-09-20 JP JP51294597A patent/JP3372259B2/ja not_active Expired - Fee Related
- 1996-09-20 HU HU9802303A patent/HUP9802303A3/hu unknown
- 1996-09-20 KR KR1019980702077A patent/KR100327922B1/ko not_active IP Right Cessation
- 1996-09-20 WO PCT/US1996/015184 patent/WO1997011053A1/en not_active Application Discontinuation
-
1998
- 1998-03-20 NO NO981282A patent/NO981282L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CA2229316A1 (en) | 1997-03-27 |
HUP9802303A2 (hu) | 1999-02-01 |
AU717238B2 (en) | 2000-03-23 |
JPH11511475A (ja) | 1999-10-05 |
EP1021401A1 (en) | 2000-07-26 |
MX9801943A (es) | 1998-08-30 |
NZ319819A (en) | 2000-02-28 |
KR19990063628A (ko) | 1999-07-26 |
CA2229316C (en) | 2005-04-12 |
AU7242696A (en) | 1997-04-09 |
NZ501318A (en) | 2001-07-27 |
KR100327922B1 (ko) | 2002-05-09 |
NO981282D0 (no) | 1998-03-20 |
HUP9802303A3 (en) | 1999-05-28 |
JP3372259B2 (ja) | 2003-01-27 |
WO1997011053A1 (en) | 1997-03-27 |
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Legal Events
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FC2A | Withdrawal, rejection or dismissal of laid open patent application |