KR100327922B1 - 칼시트리올유도체및그의용도 - Google Patents
칼시트리올유도체및그의용도 Download PDFInfo
- Publication number
- KR100327922B1 KR100327922B1 KR1019980702077A KR19980702077A KR100327922B1 KR 100327922 B1 KR100327922 B1 KR 100327922B1 KR 1019980702077 A KR1019980702077 A KR 1019980702077A KR 19980702077 A KR19980702077 A KR 19980702077A KR 100327922 B1 KR100327922 B1 KR 100327922B1
- Authority
- KR
- South Korea
- Prior art keywords
- group
- vitamin
- hydrogen
- acyl
- compound
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Physical Education & Sports Medicine (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Nutrition Science (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US53186795A | 1995-09-21 | 1995-09-21 | |
US8/531,867 | 1995-09-21 | ||
US8/531403 | 1995-09-21 | ||
US8/531867 | 1995-09-21 | ||
US08/531,867 | 1995-09-21 | ||
US08/531,403 US5952317A (en) | 1995-09-21 | 1995-09-21 | Calcitriol derivatives and their uses |
US08/531403 | 1995-09-21 | ||
PCT/US1996/015184 WO1997011053A1 (en) | 1995-09-21 | 1996-09-20 | Calcitriol derivatives and their uses |
Publications (2)
Publication Number | Publication Date |
---|---|
KR19990063628A KR19990063628A (ko) | 1999-07-26 |
KR100327922B1 true KR100327922B1 (ko) | 2002-05-09 |
Family
ID=27063537
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019980702077A KR100327922B1 (ko) | 1995-09-21 | 1996-09-20 | 칼시트리올유도체및그의용도 |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP1021401A1 (no) |
JP (1) | JP3372259B2 (no) |
KR (1) | KR100327922B1 (no) |
AU (1) | AU717238B2 (no) |
CA (1) | CA2229316C (no) |
HU (1) | HUP9802303A3 (no) |
NO (1) | NO981282L (no) |
NZ (2) | NZ319819A (no) |
WO (1) | WO1997011053A1 (no) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001011986A1 (en) * | 1999-08-17 | 2001-02-22 | Wisconsin Alumni Research Foundation | Animal feed containing hydrolyzable calcitriol derivatives |
KR100317935B1 (ko) * | 1999-10-20 | 2001-12-22 | 유승필 | 대사성 골질환 치료용 약제조성물 및 이의 제조방법 |
AU2058701A (en) | 1999-12-02 | 2001-06-12 | F. Hoffmann-La Roche Ag | Esters of vitamin D3 and uses thereof |
US20030195175A1 (en) * | 2002-03-25 | 2003-10-16 | Deluca Hector F. | Use of carbon-2-modified-vitamin D analogs to induce the formation of new bone |
BRPI0508333A (pt) | 2004-03-01 | 2007-07-17 | Bioxell Spa | uso de um composto de vitamina d, método de prevenir e/ou tratar cistite intersticial, formulação farmacêutica, composto de vitamina d, e, kit |
US20080293647A1 (en) | 2004-11-12 | 2008-11-27 | Luciano Adorini | Combined Use Of Vitamin D Derivatives And Anti-Proliferative Agents For Treating Bladder Cancer |
PT1993559T (pt) | 2006-02-03 | 2016-09-26 | Opko Renal Llc | Tratamento da insuficiência e deficiência de vitamina d com 25-hidroxivitamina d2 e 25-hidroxivitamina d3 |
SI2037936T1 (sl) | 2006-06-21 | 2014-11-28 | Opko Renal, Llc | Postopek zdravljenja in prepreäśevanja sekundarnega hiperparatiroidizma |
KR101495578B1 (ko) | 2007-04-25 | 2015-02-25 | 사이토크로마 인코포레이티드 | 비타민 d 부족 및 결핍의 치료 방법 |
EP2148683A4 (en) | 2007-04-25 | 2012-09-12 | Proventiv Therapeutics Llc | METHOD FOR THE SAFE AND EFFECTIVE TREATMENT AND PREVENTION OF SECONDARY HYPERPARATHYREOSIS IN CHRONIC KIDNEY DISEASE |
CA2943032C (en) | 2007-04-25 | 2019-05-07 | Cytochroma Inc. | Oral controlled release compositions comprising vitamin d compound and waxy carrier |
WO2008134518A2 (en) | 2007-04-25 | 2008-11-06 | Cytochroma Inc. | Methods and compounds for vitamin d therapy |
CA2714996C (en) | 2008-04-02 | 2020-04-07 | Cytochroma Inc. | Methods, compositions, uses, and kits useful for vitamin d deficiency and related disorders |
US11672809B2 (en) | 2010-03-29 | 2023-06-13 | Eirgen Pharma Ltd. | Methods and compositions for reducing parathyroid levels |
KR101847947B1 (ko) | 2013-03-15 | 2018-05-28 | 옵코 아이피 홀딩스 Ⅱ 인코포레이티드 | 안정화되고 변형된 비타민 d 방출 제형 |
AU2015298858A1 (en) | 2014-08-07 | 2017-03-02 | Opko Ireland Global Holdings Ltd. | Adjunctive therapy with 25-hydroxyvitamin D |
CR20180510A (es) | 2016-03-28 | 2019-05-15 | Opko Ireland Global Holdings Ltd | Método de tratamiento con vitamina d |
KR101983654B1 (ko) * | 2018-07-24 | 2019-05-29 | 한국과학기술원 | Cfc 증후군 환자의 발달 저해를 완화할 수 있는 치료용 조성물 |
CN114681467B (zh) * | 2022-03-30 | 2024-03-12 | 南通华山药业有限公司 | 一种阿法骨化醇杂环酯类衍生物在制备抗肿瘤药物中的应用 |
CN114656413B (zh) * | 2022-03-30 | 2024-04-09 | 南通华山药业有限公司 | 一种阿法骨化醇杂环酯类衍生物及其制备方法 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1979000513A1 (en) * | 1978-01-16 | 1979-08-09 | Wisconsin Alumni Res Found | Process for preparing 1a-hydroxylated compounds |
WO1980000339A1 (en) * | 1978-07-26 | 1980-03-06 | Wisconsin Alumni Res Found | Process for preparing 1-fluorinated vitamin d compounds |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4206131A (en) * | 1978-06-19 | 1980-06-03 | The Upjohn Company | Compounds and process |
JPS5846508A (ja) * | 1981-09-14 | 1983-03-18 | 日本石油化学株式会社 | 導電性材料の製法 |
FR2530624B1 (fr) * | 1982-07-26 | 1987-08-07 | Wisconsin Alumni Res Found | Nouveaux analogues de la vitamine d et compositions pharmaceutiques ou veterinaires les contenant |
JPH0825993B2 (ja) * | 1990-08-20 | 1996-03-13 | 大同ほくさん株式会社 | ビタミンd2およびd3又は活性型ビタミンd2およびd3の製造方法,並びにその中間体 |
JPH05339230A (ja) * | 1992-03-12 | 1993-12-21 | Nisshin Flour Milling Co Ltd | 活性型ビタミンd2及びその誘導体の製造法 |
JP3182215B2 (ja) * | 1992-06-26 | 2001-07-03 | 日清製粉株式会社 | 1−アシルオキシビタミンd誘導体 |
-
1996
- 1996-09-20 WO PCT/US1996/015184 patent/WO1997011053A1/en not_active Application Discontinuation
- 1996-09-20 EP EP96933853A patent/EP1021401A1/en not_active Withdrawn
- 1996-09-20 AU AU72426/96A patent/AU717238B2/en not_active Ceased
- 1996-09-20 CA CA002229316A patent/CA2229316C/en not_active Expired - Fee Related
- 1996-09-20 JP JP51294597A patent/JP3372259B2/ja not_active Expired - Fee Related
- 1996-09-20 KR KR1019980702077A patent/KR100327922B1/ko not_active IP Right Cessation
- 1996-09-20 NZ NZ319819A patent/NZ319819A/en unknown
- 1996-09-20 NZ NZ501318A patent/NZ501318A/en unknown
- 1996-09-20 HU HU9802303A patent/HUP9802303A3/hu unknown
-
1998
- 1998-03-20 NO NO981282A patent/NO981282L/no not_active Application Discontinuation
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1979000513A1 (en) * | 1978-01-16 | 1979-08-09 | Wisconsin Alumni Res Found | Process for preparing 1a-hydroxylated compounds |
WO1980000339A1 (en) * | 1978-07-26 | 1980-03-06 | Wisconsin Alumni Res Found | Process for preparing 1-fluorinated vitamin d compounds |
Also Published As
Publication number | Publication date |
---|---|
AU717238B2 (en) | 2000-03-23 |
NZ501318A (en) | 2001-07-27 |
JPH11511475A (ja) | 1999-10-05 |
KR19990063628A (ko) | 1999-07-26 |
HUP9802303A2 (hu) | 1999-02-01 |
HUP9802303A3 (en) | 1999-05-28 |
NO981282L (no) | 1998-05-22 |
CA2229316A1 (en) | 1997-03-27 |
AU7242696A (en) | 1997-04-09 |
CA2229316C (en) | 2005-04-12 |
MX9801943A (es) | 1998-08-30 |
JP3372259B2 (ja) | 2003-01-27 |
EP1021401A1 (en) | 2000-07-26 |
NZ319819A (en) | 2000-02-28 |
WO1997011053A1 (en) | 1997-03-27 |
NO981282D0 (no) | 1998-03-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
A201 | Request for examination | ||
E902 | Notification of reason for refusal | ||
E701 | Decision to grant or registration of patent right | ||
GRNT | Written decision to grant | ||
LAPS | Lapse due to unpaid annual fee |