NO980154D0 - Kjemiske forbindelser - Google Patents

Kjemiske forbindelser

Info

Publication number
NO980154D0
NO980154D0 NO980154A NO980154A NO980154D0 NO 980154 D0 NO980154 D0 NO 980154D0 NO 980154 A NO980154 A NO 980154A NO 980154 A NO980154 A NO 980154A NO 980154 D0 NO980154 D0 NO 980154D0
Authority
NO
Norway
Prior art keywords
chemical connections
connections
chemical
Prior art date
Application number
NO980154A
Other languages
English (en)
Other versions
NO980154L (no
Inventor
Alain Claude-Marie Daugan
Francoise Gellibert
Original Assignee
Icos Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Icos Corp filed Critical Icos Corp
Publication of NO980154D0 publication Critical patent/NO980154D0/no
Publication of NO980154L publication Critical patent/NO980154L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10Drugs for genital or sexual disorders; Contraceptives for impotence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
NO980154A 1995-07-14 1998-01-13 Sykliske GMP-spesifikke fosfodiesteraseinhibitorer NO980154L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9514465.5A GB9514465D0 (en) 1995-07-14 1995-07-14 Chemical compounds
PCT/EP1996/003025 WO1997003985A1 (en) 1995-07-14 1996-07-11 Cyclic gmp-specific phosphodiesterase inhibitors

Publications (2)

Publication Number Publication Date
NO980154D0 true NO980154D0 (no) 1998-01-13
NO980154L NO980154L (no) 1998-03-10

Family

ID=10777696

Family Applications (1)

Application Number Title Priority Date Filing Date
NO980154A NO980154L (no) 1995-07-14 1998-01-13 Sykliske GMP-spesifikke fosfodiesteraseinhibitorer

Country Status (24)

Country Link
US (1) US5981527A (no)
EP (1) EP0846118B1 (no)
JP (1) JP4150818B2 (no)
CN (1) CN1069318C (no)
AR (1) AR003455A1 (no)
AT (1) ATE216997T1 (no)
AU (1) AU702324B2 (no)
BR (1) BR9609780A (no)
CA (1) CA2226761A1 (no)
CO (1) CO4700455A1 (no)
CZ (1) CZ3298A3 (no)
DE (1) DE69621026T2 (no)
ES (1) ES2176471T3 (no)
GB (1) GB9514465D0 (no)
HR (1) HRP960321B1 (no)
HU (1) HUP9900006A3 (no)
IL (1) IL122923A0 (no)
MX (1) MX9800411A (no)
NO (1) NO980154L (no)
PL (1) PL324527A1 (no)
SK (1) SK3898A3 (no)
WO (1) WO1997003985A1 (no)
YU (1) YU42296A (no)
ZA (1) ZA965934B (no)

Families Citing this family (87)

* Cited by examiner, † Cited by third party
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US6143746A (en) 1994-01-21 2000-11-07 Icos Corporation Tetracyclic cyclic GMP-specific phosphodiesterase inhibitors, process of preparation and use
US6232312B1 (en) 1995-06-07 2001-05-15 Cell Pathways, Inc. Method for treating patient having precancerous lesions with a combination of pyrimidopyrimidine derivatives and esters and amides of substituted indenyl acetic acides
US6046206A (en) * 1995-06-07 2000-04-04 Cell Pathways, Inc. Method of treating a patient having a precancerous lesions with amide quinazoline derivatives
US6200980B1 (en) 1995-06-07 2001-03-13 Cell Pathways, Inc. Method of treating a patient having precancerous lesions with phenyl purinone derivatives
US6262059B1 (en) 1995-06-07 2001-07-17 Cell Pathways, Inc. Method of treating a patient having precancerous lesions with quinazoline derivatives
US6060477A (en) * 1995-06-07 2000-05-09 Cell Pathways, Inc. Method of treating a patient having precancerous lesions with phenyl cycloamino pyrimidinone derivatives
US5874440A (en) * 1995-06-07 1999-02-23 Cell Pathways, Inc. Method of treating a patient having precancerous lesions with phenyl pyrimidinone derivatives
GB9514473D0 (en) * 1995-07-14 1995-09-13 Glaxo Lab Sa Chemical compounds
US6331543B1 (en) 1996-11-01 2001-12-18 Nitromed, Inc. Nitrosated and nitrosylated phosphodiesterase inhibitors, compositions and methods of use
WO1998058633A2 (en) 1997-06-23 1998-12-30 Queen's University At Kingston Microdose therapy of vascular conditions by no donors
ES2137113B1 (es) 1997-07-29 2000-09-16 Almirall Prodesfarma Sa Nuevos derivados de triazolo-piridazinas heterociclicos.
US5852035A (en) * 1997-12-12 1998-12-22 Cell Pathways, Inc. Method for inhibiting neoplastic cells and related conditions by exposure to substituted N- arylmethyl and heterocyclmethyl-1H-pyrazolo (3,4-B) quinolin-4-amines
US6410584B1 (en) 1998-01-14 2002-06-25 Cell Pathways, Inc. Method for inhibiting neoplastic cells with indole derivatives
US6046199A (en) * 1998-01-14 2000-04-04 Cell Pathways, Inc. Method of inhibiting neoplastic cells with tetracyclic pyrido[3,4-B]indole derivatives
US5942520A (en) * 1998-01-27 1999-08-24 Cell Pathways, Inc. Method for inhibiting neoplastic cells by exposure to substituted N-cycloalkylmethyl-1-H-pyrazolo (3,4-B) quinolone-4 amines
US5990117A (en) * 1998-04-15 1999-11-23 Cell Pathways, Inc. Method for inhibiting neoplastic cells and related conditions by exposure to quinazoline derivatives
US6124303A (en) * 1998-09-11 2000-09-26 Cell Pathways, Inc. Method for inhibiting neoplastic cells and related conditions by exposure to 9-substituted 2-(2-N-aloxyphenyl) purin-6-ones
US6268372B1 (en) 1998-09-11 2001-07-31 Cell Pathways, Inc. Method for inhibiting neoplastic cells and related conditions by exposure to 2,9-disubstituted purin-6-ones
US6326379B1 (en) 1998-09-16 2001-12-04 Bristol-Myers Squibb Co. Fused pyridine inhibitors of cGMP phosphodiesterase
US6200771B1 (en) 1998-10-15 2001-03-13 Cell Pathways, Inc. Method of using a novel phosphodiesterase in pharmaceutical screeing to identify compounds for treatment of neoplasia
US6133271A (en) * 1998-11-19 2000-10-17 Cell Pathways, Inc. Method for inhibiting neoplastic cells and related conditions by exposure thienopyrimidine derivatives
US6187779B1 (en) 1998-11-20 2001-02-13 Cell Pathways, Inc. Method for inhibiting neoplastic cells and related conditions by exposure to 2,8-disubstituted quinazoline derivatives
US6369092B1 (en) 1998-11-23 2002-04-09 Cell Pathways, Inc. Method for treating neoplasia by exposure to substituted benzimidazole derivatives
US6034099A (en) * 1998-11-24 2000-03-07 Cell Pathways, Inc. Method for inhibiting neoplastic lesions by administering 4-(arylmethylene)- 2, 3- dihydro-pyrazol-3-ones
US6077842A (en) * 1998-11-24 2000-06-20 Cell Pathways, Inc. Method of inhibiting neoplastic cells with pyrazolopyridylpyridazinone derivatives
US6486155B1 (en) 1998-11-24 2002-11-26 Cell Pathways Inc Method of inhibiting neoplastic cells with isoquinoline derivatives
US6020379A (en) * 1999-02-19 2000-02-01 Cell Pathways, Inc. Position 7 substituted indenyl-3-acetic acid derivatives and amides thereof for the treatment of neoplasia
WO2000066114A1 (en) * 1999-04-30 2000-11-09 Lilly Icos Llc Treatment of female arousal disorder
SV2002000055A (es) * 1999-04-30 2002-07-03 Lilly Icos Llc Articulos de manufactura ref. n0. 29342/36212 sv
US6451807B1 (en) 1999-04-30 2002-09-17 Lilly Icos, Llc. Methods of treating sexual dysfunction in an individual suffering from a retinal disease, class 1 congestive heart failure, or myocardial infarction using a PDE5 inhibitor
EA004872B1 (ru) * 1999-08-03 2004-08-26 ЛИЛЛИ АЙКОС эЛ-эЛ-Си β-КАРБОЛИНОВЫЕ ФАРМАЦЕВТИЧЕСКИЕ КОМПОЗИЦИИ
US20040152106A1 (en) * 1999-10-07 2004-08-05 Robertson Harold A. Gene necessary for striatal function, uses thereof, and compounds for modulating same
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US20050070499A1 (en) * 1999-11-08 2005-03-31 Pfizer Inc. Compounds for the treatment of female sexual dysfunction
IL139456A0 (en) 1999-11-08 2001-11-25 Pfizer Compounds for the treatment of female sexual dysfunction
US6569638B1 (en) 2000-03-03 2003-05-27 Cell Pathways, Inc Method for screening compounds for the treatment of neoplasia
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ATE333457T1 (de) 2000-06-23 2006-08-15 Lilly Icos Llc Zyklische gmp-spezifische phosphodiesteraseinhibitoren
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WO2002036593A1 (en) * 2000-11-06 2002-05-10 Lilly Icos Llc Indole derivatives as pde5-inhibitors
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ES2286291T3 (es) * 2001-06-05 2007-12-01 Lilly Icos Llc Compustos tetraciclicos como inhibidores de pde5.
EP1397361B1 (en) * 2001-06-21 2006-08-09 Lilly Icos LLC Carboline derivatives as pdev inhibitors
CN1585771A (zh) * 2001-11-09 2005-02-23 先灵公司 多环鸟嘌呤衍生物磷酸二酯酶v抑制剂
JP4554931B2 (ja) 2001-12-20 2010-09-29 メルク セローノ ソシエテ アノニム プロスタグランジン調節物質としてのピロリジン誘導体
US6962940B2 (en) 2002-03-20 2005-11-08 Celgene Corporation (+)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione: methods of using and compositions thereof
US7893101B2 (en) 2002-03-20 2011-02-22 Celgene Corporation Solid forms comprising (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione, compositions thereof, and uses thereof
US7276529B2 (en) 2002-03-20 2007-10-02 Celgene Corporation Methods of the treatment or prevention of exercise-induced asthma using (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione
US7208516B2 (en) 2002-03-20 2007-04-24 Celgene Corporation Methods of the treatment of psoriatic arthritis using (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione
KR100937915B1 (ko) * 2002-07-31 2010-01-21 릴리 아이코스 엘엘씨 변형된 픽텟-스펭글러 반응 및 그것으로부터 제조된생성물
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US20150119399A1 (en) 2012-01-10 2015-04-30 President And Fellows Of Harvard College Beta-cell replication promoting compounds and methods of their use
EP2903619B1 (en) 2012-10-05 2019-06-05 Robert I. Henkin Phosphodiesterase inhibitors for treating taste and smell disorders
CN104230960B (zh) * 2013-06-06 2017-02-15 山东轩竹医药科技有限公司 四并环类间变性淋巴瘤激酶抑制剂
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Also Published As

Publication number Publication date
HRP960321B1 (en) 2003-06-30
ATE216997T1 (de) 2002-05-15
CZ3298A3 (cs) 1998-06-17
DE69621026T2 (de) 2002-08-22
EP0846118B1 (en) 2002-05-02
AR003455A1 (es) 1998-08-05
NO980154L (no) 1998-03-10
GB9514465D0 (en) 1995-09-13
ZA965934B (en) 1997-02-03
WO1997003985A1 (en) 1997-02-06
ES2176471T3 (es) 2002-12-01
CA2226761A1 (en) 1997-02-06
SK3898A3 (en) 1998-11-04
CO4700455A1 (es) 1998-12-29
HRP960321A2 (en) 1998-08-31
BR9609780A (pt) 1999-03-09
YU42296A (sh) 1998-12-23
IL122923A0 (en) 1998-08-16
HUP9900006A2 (hu) 1999-04-28
AU6419296A (en) 1997-02-18
JP4150818B2 (ja) 2008-09-17
CN1195349A (zh) 1998-10-07
JPH11509535A (ja) 1999-08-24
DE69621026D1 (de) 2002-06-06
CN1069318C (zh) 2001-08-08
AU702324B2 (en) 1999-02-18
PL324527A1 (en) 1998-06-08
US5981527A (en) 1999-11-09
MX9800411A (es) 1998-04-30
HUP9900006A3 (en) 1999-11-29
EP0846118A1 (en) 1998-06-10

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