NO975320L - Kontinuerlige, fluorkjemiske mikrodispersjoner for avlevering av farmasöytiske midler - Google Patents

Kontinuerlige, fluorkjemiske mikrodispersjoner for avlevering av farmasöytiske midler

Info

Publication number
NO975320L
NO975320L NO975320A NO975320A NO975320L NO 975320 L NO975320 L NO 975320L NO 975320 A NO975320 A NO 975320A NO 975320 A NO975320 A NO 975320A NO 975320 L NO975320 L NO 975320L
Authority
NO
Norway
Prior art keywords
pharmaceutical
pharmaceutical composition
delivery
pharmaceutical agents
preparing
Prior art date
Application number
NO975320A
Other languages
English (en)
Other versions
NO975320D0 (no
Inventor
Leo A Trevino
Luis A Dellamary
Thomas E Tarara
Jeffry G Weers
Helen M Ranney
Original Assignee
Alliance Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alliance Pharma filed Critical Alliance Pharma
Publication of NO975320D0 publication Critical patent/NO975320D0/no
Publication of NO975320L publication Critical patent/NO975320L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0026—Blood substitute; Oxygen transporting formulations; Plasma extender

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

En fremgangsmåte for fremstilling av en farmasøytisk mikrodlspers^on som viser forbedret blotllgjengellghet, omfatter: å tilveiebringe en termodynamisk stabil, farmasøytisk blanding omfattende minst et farmasøytisk middel inn- arbeidet l en fysiologisk akseptabel, nytende bærer, Idet bæreren består av en eller flere lipofile Huor- forbindelser og minst et ikke-fluorert medoppløsnlngsmlddel; og å kombinere den stabile, farmasøytiske blanding med en mengde av minst et nuorkjemlsk fortynnlngsmiddel tilstrekkelig til å initiere faseseparering for nevnte minst ene farmasøytiske middel fra den termodynamisk stabile, farmasøytiske blanding der en farmasøytisk mikrodispersjon dannes. Det beskrives videre mikrodlspergerte, farmasøytiske preparater og en kit for å fremstille slike preparater.
NO975320A 1995-06-07 1997-11-19 Kontinuerlige, fluorkjemiske mikrodispersjoner for avlevering av farmasöytiske midler NO975320L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/482,176 US5667809A (en) 1995-06-07 1995-06-07 Continuous fluorochemical microdispersions for the delivery of lipophilic pharmaceutical agents
PCT/US1996/009081 WO1996040053A1 (en) 1995-06-07 1996-06-05 Continuous fluorochemical microdispersions for the delivery of pharmaceutical agents

Publications (2)

Publication Number Publication Date
NO975320D0 NO975320D0 (no) 1997-11-19
NO975320L true NO975320L (no) 1998-01-27

Family

ID=23915021

Family Applications (1)

Application Number Title Priority Date Filing Date
NO975320A NO975320L (no) 1995-06-07 1997-11-19 Kontinuerlige, fluorkjemiske mikrodispersjoner for avlevering av farmasöytiske midler

Country Status (18)

Country Link
US (1) US5667809A (no)
EP (1) EP0831770B1 (no)
JP (1) JPH11506783A (no)
KR (1) KR100454377B1 (no)
CN (1) CN1192135A (no)
AT (1) ATE195415T1 (no)
AU (1) AU721759B2 (no)
CA (1) CA2222081A1 (no)
DE (1) DE69609834T2 (no)
DK (1) DK0831770T3 (no)
ES (1) ES2150674T3 (no)
GR (1) GR3034657T3 (no)
HU (1) HUP9900872A2 (no)
IL (1) IL122241A0 (no)
NO (1) NO975320L (no)
PL (1) PL323829A1 (no)
PT (1) PT831770E (no)
WO (1) WO1996040053A1 (no)

Families Citing this family (67)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3211740B2 (ja) * 1997-08-28 2001-09-25 ダイキン工業株式会社 化粧料
US6433040B1 (en) 1997-09-29 2002-08-13 Inhale Therapeutic Systems, Inc. Stabilized bioactive preparations and methods of use
US6309623B1 (en) 1997-09-29 2001-10-30 Inhale Therapeutic Systems, Inc. Stabilized preparations for use in metered dose inhalers
US6565885B1 (en) 1997-09-29 2003-05-20 Inhale Therapeutic Systems, Inc. Methods of spray drying pharmaceutical compositions
US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
US6946117B1 (en) 1997-09-29 2005-09-20 Nektar Therapeutics Stabilized preparations for use in nebulizers
US6410255B1 (en) * 1999-05-05 2002-06-25 Aurora Biosciences Corporation Optical probes and assays
PT1178952E (pt) 1999-05-14 2007-12-04 Univ California Novos moduladores da interleucina-1 e do factor alfa de necrose tumoral, síntese dos referidos moduladores e métodos de utilização dos referidos moduladores
DE60139544D1 (de) 2000-02-23 2009-09-24 Life Technologies Corp Veränderte, fluoreszierende proteine
US8404217B2 (en) 2000-05-10 2013-03-26 Novartis Ag Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
WO2001085136A2 (en) 2000-05-10 2001-11-15 Alliance Pharmaceutical Corporation Phospholipid-based powders for drug delivery
JP4395549B2 (ja) * 2000-11-16 2010-01-13 ザ レジェンツ オブ ザ ユニヴァースティ オブ カリフォルニア 薬物及び発酵生成物の発見のための海洋放線菌分類群
US20050048126A1 (en) 2000-12-22 2005-03-03 Barrett Rabinow Formulation to render an antimicrobial drug potent against organisms normally considered to be resistant to the drug
US9700866B2 (en) 2000-12-22 2017-07-11 Baxter International Inc. Surfactant systems for delivery of organic compounds
US8067032B2 (en) 2000-12-22 2011-11-29 Baxter International Inc. Method for preparing submicron particles of antineoplastic agents
US7244703B2 (en) * 2001-06-22 2007-07-17 Bentley Pharmaceuticals, Inc. Pharmaceutical compositions and methods for peptide treatment
US20060003012A9 (en) 2001-09-26 2006-01-05 Sean Brynjelsen Preparation of submicron solid particle suspensions by sonication of multiphase systems
MXPA04002446A (es) 2001-09-26 2004-07-23 Baxter Int Preparacion de nanoparticulas de tamano de submicras mediante dispersion y remocion de la fase liquida o solvente.
MXPA04005865A (es) * 2001-12-19 2004-09-13 Nektar Therapeutics Suministro de aminoglucosidos a los pulmones.
US7176232B2 (en) 2002-06-24 2007-02-13 The Regents Of The University Of California Salinosporamides and methods for use thereof
AU2003296908A1 (en) * 2002-09-27 2004-05-04 Nereus Pharmaceuticals, Inc. Macrocyclic lactams
GB0307403D0 (en) * 2003-03-31 2003-05-07 Medical Res Council Selection by compartmentalised screening
CN101791306A (zh) * 2003-06-20 2010-08-04 加利福尼亚大学董事会 盐孢菌酰胺及其使用方法
JP2007523862A (ja) * 2003-06-20 2007-08-23 ネレアス ファーマシューティカルズ インコーポレイテッド 癌、炎症及び感染性疾患の治療のための、［３．２．０］複素環式化合物およびそれらの類縁体の使用
US7727752B2 (en) 2003-07-29 2010-06-01 Life Technologies Corporation Kinase and phosphatase assays
CN101829319A (zh) 2003-12-08 2010-09-15 Cpex药品公司 用于胰岛素治疗的药用组合物及方法
BRPI0506535A (pt) * 2004-01-23 2007-02-27 Nereus Pharmaceuticals Inc pirroles bis-indole úteis como agentes anti-microbiais
NZ550910A (en) * 2004-04-30 2011-06-30 Nereus Pharmaceuticals Inc [3.2.0] Heterocyclic compounds and methods of using the same
US7579371B2 (en) 2004-04-30 2009-08-25 Nereus Pharmaceuticals, Inc. Methods of using [3.2.0] heterocyclic compounds and analogs thereof
JP5676071B2 (ja) * 2004-12-03 2015-02-25 ダナ ファーバー キャンサー インスティテュート，インコーポレイテッド 腫瘍性疾患を治療するための組成物及び方法
DE102005009194B4 (de) * 2005-03-01 2006-12-14 Hpp-Hommel Pharmaceuticals Production Gmbh Verfahren zur Herstellung von polymorph stabilem Triamcinolonacetonid
KR20080035650A (ko) 2005-07-21 2008-04-23 니리어스 파마슈티컬즈, 인코퍼레이션 인터루킨―1 및 종양괴사인자―ａ 조정자들, 이러한조정자들의 합성 및 이들의 사용 방법
US7319570B2 (en) 2005-09-19 2008-01-15 Seagate Technology Llc Random vibration and shock compensator using a disturbance observer
US7824698B2 (en) * 2007-02-02 2010-11-02 Nereus Pharmaceuticals, Inc. Lyophilized formulations of Salinosporamide A
US8722736B2 (en) 2007-05-22 2014-05-13 Baxter International Inc. Multi-dose concentrate esmolol with benzyl alcohol
US8426467B2 (en) 2007-05-22 2013-04-23 Baxter International Inc. Colored esmolol concentrate
US20090017167A1 (en) * 2007-07-11 2009-01-15 Herbalife International Inc. Mixture and beverage made therefrom for protecting cellular hydration
US8394816B2 (en) * 2007-12-07 2013-03-12 Irene Ghobrial Methods of using [3.2.0] heterocyclic compounds and analogs thereof in treating Waldenstrom's Macroglobulinemia
KR20110011645A (ko) * 2008-05-12 2011-02-08 니리어스 파마슈티컬즈, 인코퍼레이션 프로테아좀 저해제로서의 살리노스포라마이드 유도체
EP2123256A1 (en) 2008-05-19 2009-11-25 Ruhr-Universität Bochum Perfluorcarbon nanoemulsions with endocytosis enhancing surface for gene-transfer
MX2012010684A (es) 2010-03-17 2012-11-06 Novaliq Gmbh Composicion farmaceutica para el tratamiento de la presion intraocular incrementada.
EP2444063A1 (en) * 2010-10-20 2012-04-25 Novaliq GmbH Liquid pharmaceutical compositions for the delivery of active ingredients
EP2462921A1 (en) 2010-11-11 2012-06-13 Novaliq GmbH Liquid pharmaceutical compositions for the treatment of a posterior eye disease
ES2617968T3 (es) 2011-05-25 2017-06-20 Novaliq Gmbh Composición farmacéutica para la administración a uñas
CA2834855C (en) * 2011-05-25 2020-12-29 Novaliq Gmbh Topical pharmaceutical composition based on semifluorinated alkanes
JP5902405B2 (ja) 2011-06-15 2016-04-13 日本オーチス・エレベータ株式会社 エレベータ装置
MX361681B (es) 2012-01-23 2018-12-13 Novaliq Gmbh Composiciones de proteína estabilizadas basadas en alcanos semifluorados.
ES2974663T3 (es) 2012-09-12 2024-07-01 Novaliq Gmbh Alcanos semifluorados para uso en la solubilización de meibomio
CA2883003C (en) 2012-09-12 2021-11-16 Novaliq Gmbh Semifluorinated alkane compositions
CA2918419C (en) 2013-07-23 2022-05-03 Novaliq Gmbh Stabilized antibody compositions
CN106794986A (zh) 2014-09-02 2017-05-31 布平德尔·辛格 氘化或非氘化分子以及药物制剂
WO2016057563A1 (en) 2014-10-08 2016-04-14 Pacific Northwest Diabetes Research Institute Methods and compositions for increasing the potency of antifungal agents
AU2016329261B2 (en) 2015-09-30 2020-05-07 Novaliq Gmbh Semifluorinated compounds for ophthalmic administration
DK3355990T3 (da) 2015-09-30 2019-09-16 Novaliq Gmbh Semifluorinerede forbindelser og disses sammensætninger
PT3442480T (pt) 2016-06-23 2019-12-23 Novaliq Gmbh Método de administração tópica
MX2019003363A (es) 2016-09-22 2019-10-02 Novaliq Gmbh Composiciones farmaceuticas para usarse en la terapia de la blefaritis.
AU2017329983B2 (en) 2016-09-23 2022-05-05 Novaliq Gmbh Ophthalmic compositions comprising ciclosporin
EP3612228B1 (en) 2017-04-21 2023-08-23 Dermaliq Therapeutics, Inc. Iodine compositions
US11278503B2 (en) 2017-05-12 2022-03-22 Novaliq Gmbh Pharmaceutical compositions comprising semifluorinated alkanes for the treatment of contact lense-related conditions
JP2020535156A (ja) 2017-09-27 2020-12-03 ノバリック ゲーエムベーハー 眼疾患の治療に使用するためのラタノプロストを含む眼科用組成物
CN111182893A (zh) 2017-10-04 2020-05-19 诺瓦利克有限责任公司 包含f6h8的眼用组合物
JP7353292B2 (ja) 2018-03-02 2023-09-29 ノバリック ゲーエムベーハー ネビボロールを含む医薬組成物
MX2020010036A (es) 2018-03-28 2021-03-02 Herbalife Int Of America Inc Acetilacion de polisacaridos.
US12029757B2 (en) 2018-09-27 2024-07-09 Dermaliq Therapeutics, Inc. Lipid barrier repair
ES2950878T3 (es) 2018-09-27 2023-10-16 Dermaliq Therapeutics Inc Formulación de protección solar de uso tópico
JP7500550B2 (ja) 2018-10-12 2024-06-17 ノバリック ゲーエムベーハー 乾性眼疾患の治療のための眼科用組成物

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3975512A (en) * 1970-12-21 1976-08-17 University Of Illinois Foundation Non-toxic brominated perfluorocarbons radiopaque agents
GB8501015D0 (en) * 1985-01-16 1985-02-20 Riker Laboratories Inc Drug
US4987154A (en) * 1986-01-14 1991-01-22 Alliance Pharmaceutical Corp. Biocompatible, stable and concentrated fluorocarbon emulsions for contrast enhancement and oxygen transport in internal animal use
US5284645A (en) * 1987-08-05 1994-02-08 Alliance Pharmaceutical Corp. Fluorocarbon emulsions containing amino acid based anti-inflamatory agents and buffer systems
FR2602774B1 (fr) * 1986-07-29 1990-10-19 Atta Nouvelles molecules amphiphiles polyhydroxylees et perfluoroalkylees ayant des proprietes tensioactives
FR2620445B1 (fr) * 1987-09-16 1990-07-20 Centre Nat Rech Scient Nouveaux derives fluores d'acides amines, utilisables en particulier comme agents tensioactifs ou cotensioactifs et preparations a usage biomedical comprenant ces derives
US5114703A (en) * 1989-05-30 1992-05-19 Alliance Pharmaceutical Corp. Percutaneous lymphography using particulate fluorocarbon emulsions
EP0478686B1 (en) * 1989-06-22 1993-08-11 Applications Et Transferts De Technologies Avancees Atta Fluorine and phosphorous-containing amphiphilic molecules with surfactant properties
FR2665705B1 (fr) * 1990-08-09 1993-07-30 Atta Nouveaux derives fluores amphiphiles a structure telomere, leur procede de preparation et leur utilisation dans des preparations a usage biomedical.
US5292499A (en) * 1990-09-11 1994-03-08 University Of Wales College Of Cardiff Method of preparing medical aerosol formulations including drug dissolved in reverse micelles
US5230884A (en) * 1990-09-11 1993-07-27 University Of Wales College Of Cardiff Aerosol formulations including proteins and peptides solubilized in reverse micelles and process for making the aerosol formulations
US5173298A (en) * 1990-09-27 1992-12-22 Allergan, Inc. Nonaqueous fluorinated drug delivery vehicle suspensions
US5496535A (en) * 1991-04-12 1996-03-05 Alliance Pharmaceutical Corp. Fluorocarbon contrast media for use with MRI and radiographic imaging
FR2679150A1 (fr) * 1991-07-17 1993-01-22 Atta Preparations comprenant un fluorocarbure ou compose hautement fluore et un compose organique lipophile-fluorophile, et leurs utilisations.
WO1994014415A1 (en) * 1992-12-24 1994-07-07 Hemagen/Pfc Fluorocarbon emulsions
FR2700696B1 (fr) * 1993-01-28 1995-04-07 Atta Dispersions, émulsions, microémulsions, gels et compositions à usage biomédical comprenant un composé organique fluoré iodé, utilisables notamment comme agent de contraste.
FR2720943B1 (fr) * 1994-06-09 1996-08-23 Applic Transferts Technolo Emulsions inverses stables à forte concentration en composé(s) fluoré(s) et leur utilisation pour l'administration pulmonaire de médicaments et pour la fabrication d'émulsions multiples.

Also Published As

Publication number Publication date
GR3034657T3 (en) 2001-01-31
KR19990022587A (ko) 1999-03-25
CA2222081A1 (en) 1996-12-19
JPH11506783A (ja) 1999-06-15
DE69609834D1 (de) 2000-09-21
DE69609834T2 (de) 2000-12-21
ATE195415T1 (de) 2000-09-15
US5667809A (en) 1997-09-16
EP0831770A1 (en) 1998-04-01
IL122241A0 (en) 1998-04-05
CN1192135A (zh) 1998-09-02
PT831770E (pt) 2000-11-30
ES2150674T3 (es) 2000-12-01
WO1996040053A1 (en) 1996-12-19
NO975320D0 (no) 1997-11-19
HUP9900872A2 (hu) 1999-08-30
AU6049496A (en) 1996-12-30
PL323829A1 (en) 1998-04-27
EP0831770B1 (en) 2000-08-16
MX9709690A (es) 1998-03-29
KR100454377B1 (ko) 2005-08-04
AU721759B2 (en) 2000-07-13
DK0831770T3 (da) 2000-12-18

Similar Documents

Publication Publication Date Title
NO975320L (no) Kontinuerlige, fluorkjemiske mikrodispersjoner for avlevering av farmasöytiske midler
NO20100034L (no) Fenofibrat farmasoytisk blanding som har hoy biotilgjengelighet og fremgangsmate for fremstilling av den
JO2247B1 (en) Method for preparing a compound
NO954245L (no) Cyklosporinholdig pulverblanding
CA2176360A1 (en) Pharmaceutical emulsion
IL131609A0 (en) Hydrophilic binary systems for the administration of cyclosporine
HK1028877A1 (en) Self-emulsifying formulation for lipophilic compounds
MY145753A (en) Novel cyclosporin analog formulations
CA2294031A1 (en) SELF-EMULSIFYING FORMULATION FOR LIPOPHILIC COMPOUNDS
HUP0204143A2 (en) Tricyclic 1-benzylpyrazoles-3-carboxylic acid derivatives, preparation of the compounds, their use and pharmaceutical compositions containing them
GR3031233T3 (en) Selective system scan for multizone radiotelephone subscriber units.
NO974104L (no) Faste diacyl-organiske peroksyd-dispersjoner
NO951422L (no) Farmasöytiske sammensetninger for behandling av osteoporose
YU24402A (sh) 2'-supstituisani 1,1'-bifenil-2-karbonamidi, postupak za njihovu proizvodnju, njihova primena kao leka kao i farmaceutski preparati koji sadrže ta jedinjenja
NO995928L (no) Alfa-1-antitrypsin-preparater samt fremgangsmåte ved fremstilling derav
DK0756489T3 (da) Cyclosporinholdigt præparat og fremgangsmåde til fremstillingen af dette
NO870560L (no) Nytt farmasoeytisk preparat.
KR940703651A (ko) 리포솜 이트라코나졸 제제[liposomal itraconazole formula-tions]
DK0630365T3 (da) Fremgangsmåde til fremstilling af beta-phenylisoserin og analoge deraf
AU3777197A (en) Cyclosporin formulation
PL338294A1 (en) Derivatives of streptogramins, method of obtaining them and compositions containing such derivatives
EP0056681A3 (en) Levonantradol and n-methyllevonantradol formulations
Hotta Tsuchiya, K.: Kartini's Image of Java's Landscape
Silber et al. Antiischemic effects of a newly developed capsule containing 120 mg isosorbide dinitrate in sustained release form
CA2025663A1 (en) Indole derivatives

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application