NO974740D0 - IGF-1 renseprosess - Google Patents

IGF-1 renseprosess

Info

Publication number
NO974740D0
NO974740D0 NO974740A NO974740A NO974740D0 NO 974740 D0 NO974740 D0 NO 974740D0 NO 974740 A NO974740 A NO 974740A NO 974740 A NO974740 A NO 974740A NO 974740 D0 NO974740 D0 NO 974740D0
Authority
NO
Norway
Prior art keywords
igf
unfolding
refolding
reverse phase
cation exchange
Prior art date
Application number
NO974740A
Other languages
English (en)
Other versions
NO974740L (no
NO322326B1 (no
Inventor
Russell A Brierley
Joan N Abrams
John M Hanson
Francis C Maslanka
Original Assignee
Cephalon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cephalon Inc filed Critical Cephalon Inc
Publication of NO974740D0 publication Critical patent/NO974740D0/no
Publication of NO974740L publication Critical patent/NO974740L/no
Publication of NO322326B1 publication Critical patent/NO322326B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/65—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO19974740A 1995-04-14 1997-10-13 Fremgangsmate for rensing av korrekt foldet monomer - insulinlignende vekstfaktor-1 (IGF-1) NO322326B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/422,436 US5650496A (en) 1995-04-14 1995-04-14 IGF-I purification process
PCT/US1996/005099 WO1996032407A1 (en) 1995-04-14 1996-04-12 Igf-i purification process

Publications (3)

Publication Number Publication Date
NO974740D0 true NO974740D0 (no) 1997-10-13
NO974740L NO974740L (no) 1997-12-12
NO322326B1 NO322326B1 (no) 2006-09-18

Family

ID=23674879

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19974740A NO322326B1 (no) 1995-04-14 1997-10-13 Fremgangsmate for rensing av korrekt foldet monomer - insulinlignende vekstfaktor-1 (IGF-1)

Country Status (11)

Country Link
US (2) US5650496A (no)
EP (1) EP0820463B1 (no)
JP (1) JP3894570B2 (no)
AT (1) ATE415411T1 (no)
AU (2) AU696516B2 (no)
CA (1) CA2218111C (no)
DE (1) DE69637760D1 (no)
ES (1) ES2321242T3 (no)
NO (1) NO322326B1 (no)
NZ (1) NZ306782A (no)
WO (1) WO1996032407A1 (no)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH10504971A (ja) * 1994-09-08 1998-05-19 カイロン コーポレイション インスリン様増殖因子の改善された生産方法
US6756484B1 (en) 1995-04-14 2004-06-29 Cephalon, Inc. IGF-I purification process
JP2002514890A (ja) * 1995-06-07 2002-05-21 カイロン コーポレイション 酵母宿主から真性のｉｇｆを精製するための方法
US7071313B1 (en) * 1995-06-07 2006-07-04 Cephalon, Inc. Methods of purifying authentic IGF from yeast hosts
US7193042B1 (en) 1995-06-07 2007-03-20 Chiron Corporation Methods for purifying authentic IGF from yeast hosts
CN1268639C (zh) * 1996-11-15 2006-08-09 基因技术股份有限公司 神经营养蛋白的纯化
AU2151401A (en) 1999-12-22 2001-07-03 Novo Nordisk A/S Method for extractive refolding of scrambled single-chain polypeptides
GB0011278D0 (en) 2000-05-10 2000-06-28 Univ London Repair of nerve damage
AU2001279073B2 (en) * 2000-07-28 2006-08-24 Christopher J. Murphy Transplant media
AU2002327795A1 (en) * 2001-10-09 2003-04-22 The Government Of The United States Of America, As Represented By The Department Of Health And Human Methods and compositions for production and purification of recombinant staphylococcal enterotoxin b (rseb)
KR20030044696A (ko) * 2001-11-30 2003-06-09 정종문 피키아 파스토리스에서 재조합 인슐린 유사 성장인자-1단백질을 연속적으로 생산하는 방법
GB0202906D0 (en) 2002-02-07 2002-03-27 Univ London Prevention of myocardial damage
US7229554B2 (en) * 2002-09-25 2007-06-12 Novo Nordisk A/S Purification process comprising microfiltration at elevated temperatures
US20070207209A1 (en) * 2004-08-27 2007-09-06 Murphy Christopher J Trophic factor combinations for nervous system treatment
WO2006097682A1 (en) * 2005-03-18 2006-09-21 Ucl Business Plc Mechano growth factor peptides and their use
KR102028628B1 (ko) 2008-09-02 2019-10-04 나트릭스 세퍼레이션즈, 인코포레이티드 크로마토그래피 막, 이를 포함하는 장치 및 이의 이용방법
UA105785C2 (uk) 2009-02-19 2014-06-25 Кселлія Фармасьютікалз Апс Спосіб очищення ліпопептидів
CA2780095C (en) * 2009-11-13 2018-12-11 Natrix Separations Inc. Hydrophobic interaction chromatography membranes, and methods of use thereof
WO2012158896A2 (en) 2011-05-17 2012-11-22 Natrix Separations Inc. Layered tubular membranes for chromatography, and methods of use thereof
AU2018212974B2 (en) * 2017-01-30 2023-08-24 Regeneron Pharmaceuticals, Inc. Compositions and methods for reducing bioburden in chromatography
KR20230098304A (ko) * 2020-11-05 2023-07-03 시믹 홀딩스 씨오., 엘티디. 재조합 인슐린 유사 성장 인자 i의 제조 방법

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5093317A (en) * 1989-06-05 1992-03-03 Cephalon, Inc. Treating disorders by application of insulin-like growth factor
AU8417091A (en) * 1990-08-20 1992-03-17 Novo Nordisk A/S Biologically active compound, a process for the preparation thereof and use of the same
JPH06500470A (ja) * 1990-09-04 1994-01-20 メルク　エンド　カンパニー　インコーポレーテッド メチロトローフ酵母細胞におけるインスリン様成長因子の産生
US5231178A (en) * 1991-01-16 1993-07-27 The Salk Institute Biotechnology/Industrial Associates, Inc. Method for the purification of intact, correctly-folded insulin-like growth factor-1
US5288931A (en) * 1991-12-06 1994-02-22 Genentech, Inc. Method for refolding insoluble, misfolded insulin-like growth factor-I into an active conformation
WO1993019084A1 (en) * 1992-03-24 1993-09-30 Synergen, Inc. Refolding and purification of insulin-like growth factor i
US5663304A (en) * 1993-08-20 1997-09-02 Genentech, Inc. Refolding of misfolded insulin-like growth factor-I
US5407810A (en) * 1993-08-20 1995-04-18 Genentech, Inc. Aqueous multiple-phase isolation of polypeptide
US5451660A (en) * 1993-12-13 1995-09-19 Genentech, Inc. Method for purifying polypeptides
US5446024A (en) * 1993-12-17 1995-08-29 Genentech, Inc. Purification of insulin-like growth factor

Also Published As

Publication number Publication date
CA2218111C (en) 2008-07-08
AU2007201259A1 (en) 2007-04-05
NZ306782A (en) 1998-11-25
EP0820463A4 (en) 2001-08-08
JPH11503733A (ja) 1999-03-30
NO974740L (no) 1997-12-12
NO322326B1 (no) 2006-09-18
DE69637760D1 (de) 2009-01-08
US5650496A (en) 1997-07-22
AU696516B2 (en) 1998-09-10
ES2321242T3 (es) 2009-06-03
US6207806B1 (en) 2001-03-27
WO1996032407A1 (en) 1996-10-17
ATE415411T1 (de) 2008-12-15
CA2218111A1 (en) 1996-10-17
EP0820463A1 (en) 1998-01-28
AU5543396A (en) 1996-10-30
JP3894570B2 (ja) 2007-03-22
EP0820463B1 (en) 2008-11-26

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