NO971218D0 - Tetrahydrofuran-antifungale midler - Google Patents

Tetrahydrofuran-antifungale midler

Info

Publication number
NO971218D0
NO971218D0 NO971218A NO971218A NO971218D0 NO 971218 D0 NO971218 D0 NO 971218D0 NO 971218 A NO971218 A NO 971218A NO 971218 A NO971218 A NO 971218A NO 971218 D0 NO971218 D0 NO 971218D0
Authority
NO
Norway
Prior art keywords
antifungal agents
tetrahydrofuran
tetrahydrofuran antifungal
agents
antifungal
Prior art date
Application number
NO971218A
Other languages
English (en)
Other versions
NO971218L (no
Inventor
Anil K Saksena
Viyyoor M Girijavallabhan
Raymond G Lovey
Russel E Pike
Haiyan Wang
Yi-Tsung Liu
Ashit Kumar Ganguly
Frank Bennett
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/458,543 external-priority patent/US5714490A/en
Priority claimed from US08/459,145 external-priority patent/US5693626A/en
Priority claimed from US08/459,225 external-priority patent/US5710154A/en
Application filed by Schering Corp filed Critical Schering Corp
Publication of NO971218D0 publication Critical patent/NO971218D0/no
Publication of NO971218L publication Critical patent/NO971218L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
NO971218A 1995-06-02 1997-03-17 Tetrahydrofuran-antifungale midler NO971218L (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US08/458,543 US5714490A (en) 1993-12-21 1995-06-02 Tetrahydrofuran antifungals
US08/459,145 US5693626A (en) 1993-12-21 1995-06-02 Tetrahydrofuran antifungals
US08/459,225 US5710154A (en) 1993-12-21 1995-06-02 Tetrahydrofuran antifungals
PCT/US1996/007547 WO1996038443A1 (en) 1995-06-02 1996-05-30 Tetrahydrofuran antifungals

Publications (2)

Publication Number Publication Date
NO971218D0 true NO971218D0 (no) 1997-03-17
NO971218L NO971218L (no) 1997-03-17

Family

ID=27412736

Family Applications (1)

Application Number Title Priority Date Filing Date
NO971218A NO971218L (no) 1995-06-02 1997-03-17 Tetrahydrofuran-antifungale midler

Country Status (19)

Country Link
EP (1) EP0773941B1 (no)
CN (1) CN1073109C (no)
AR (1) AR002751A1 (no)
AT (1) ATE240319T1 (no)
AU (1) AU5928096A (no)
CA (1) CA2197672C (no)
CZ (1) CZ59497A3 (no)
DE (1) DE69628117T2 (no)
ES (1) ES2199291T3 (no)
HK (1) HK1008821A1 (no)
HU (1) HUP9701690A3 (no)
IL (1) IL118464A (no)
MX (1) MX9701229A (no)
NO (1) NO971218L (no)
NZ (1) NZ309281A (no)
PL (1) PL319635A1 (no)
SK (1) SK27097A3 (no)
TW (1) TW357146B (no)
WO (1) WO1996038443A1 (no)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL128513A (en) * 1997-02-11 2002-11-10 Janssen Pharmaceutica Nv Aster derivatives of amino acids of Azuli substance against fungi, their preparation and pharmaceutical preparations containing them
AU9592998A (en) * 1997-10-07 1999-04-27 Schering Corporation Crystalline antifungal glycine ester polymorph
ID29290A (id) * 1997-10-07 2001-08-16 Schering Corp Susunan kristal bentuk-banyak yang dapat membasmi jamur
US6713481B1 (en) * 1997-10-17 2004-03-30 David R. Andrews Crystalline antifungal polymorph
US5883097A (en) * 1998-04-16 1999-03-16 Schering Corporation Soluble azole antifungal salt
EP0957101A1 (en) * 1998-05-14 1999-11-17 Janssen Pharmaceutica N.V. Water soluble azoles as broad-spectrum antifungals
AU1915500A (en) 1998-11-20 2000-06-13 Bristol-Myers Squibb Company Water soluble prodrugs of azole compounds
CN1349540A (zh) * 1999-05-04 2002-05-15 詹森药业有限公司 抗真菌的醚类
US6362172B2 (en) 2000-01-20 2002-03-26 Bristol-Myers Squibb Company Water soluble prodrugs of azole compounds
US6448401B1 (en) 2000-11-20 2002-09-10 Bristol-Myers Squibb Company Process for water soluble azole compounds
EP2130540A1 (en) 2008-06-02 2009-12-09 Sandoz AG Pharmaceutical compositions containing a crystalline form of posaconazole
EP2141159A1 (en) 2008-07-03 2010-01-06 Sandoz AG A Crystalline form of posaconazole
WO2011003992A1 (en) 2009-07-09 2011-01-13 Sandoz Ag A crystalline form of posaconazole
CN102234267A (zh) * 2010-04-21 2011-11-09 中国科学院上海药物研究所 新型三氮唑类抗真菌化合物、其药物组合物及其制备方法和用途
WO2011144655A1 (en) 2010-05-19 2011-11-24 Sandoz Ag Process for the preparation of chiral hydrazides
EP2571868B1 (en) * 2010-05-19 2016-05-04 Sandoz AG Preparation of posaconazole intermediates
CA2798002C (en) 2010-05-19 2019-12-03 Sandoz Ag Process for the preparation of chiral triazolones
EP2571869B1 (en) * 2010-05-19 2015-09-23 Sandoz AG Purification of posaconazole and posaconazole intermediates
CN108329303A (zh) 2011-06-16 2018-07-27 桑多斯股份公司 制备手性化合物的方法
WO2015011224A1 (en) 2013-07-25 2015-01-29 Sandoz Ag Improved process for the preparation of crystalline form iv of posaconazole
ITMI20132114A1 (it) 2013-12-18 2015-06-19 Djada Pharmaceutical Sa Una forma cristallina di posaconazolo
CN104370894A (zh) * 2014-10-21 2015-02-25 江苏恒盛药业有限公司 无定型泊沙康唑的制备工艺
CN105622591B (zh) * 2014-11-06 2018-09-21 博瑞生物医药（苏州）股份有限公司 一种新型三唑类抗真菌药物的制备方法
BR112017008481B1 (pt) 2014-12-05 2022-09-06 Pulmocide Limited Composto antimicótico, uso do referido composto, composição farmacêutica e processo para preparar o mesmo
DK3298006T3 (da) 2015-05-21 2020-03-30 Pulmocide Ltd Antifungal 4-(4-(4-(((3r,5r)-5-((1h-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorphenyl)tetrahydrofuran-3-yl)methoxy)-3-methylphenyl)piperazin-1-yl)-n-(2-hydroxycyclohexyl)benzamid eller et farmaceutisk acceptabelt salt deraf
CN106432338A (zh) * 2015-08-08 2017-02-22 陕西合成药业股份有限公司 泊沙康唑衍生物、合成和在长效制剂中的用途
CN105606736A (zh) * 2016-01-27 2016-05-25 重庆华邦制药有限公司 分离测定泊沙康唑中间体z1及其有关物质的方法
WO2017133632A1 (zh) * 2016-02-04 2017-08-10 武汉朗来科技发展有限公司 泊沙康唑衍生物、其药物组合物和用途
CN105949278B (zh) * 2016-03-30 2019-12-06 南京曼杰生物科技有限公司 一种取代的四氢呋喃水溶性衍生物及其应用
CN106866459A (zh) * 2017-03-30 2017-06-20 成都绿林科技有限公司 一种抗真菌药物中间体的制备方法
CN106986787A (zh) * 2017-03-30 2017-07-28 成都绿林科技有限公司 一种泊沙康唑中间体的合成方法
CN110938093B (zh) * 2018-09-21 2022-08-19 华创合成制药股份有限公司 一种泊沙康唑磷酸酯单胆碱盐及其制备方法和用途
CN113666915B (zh) * 2021-08-27 2022-08-16 江苏海洋大学 一种泊沙康唑中间体的制备方法
CN114315811B (zh) * 2021-11-19 2024-04-30 江苏恒盛药业有限公司 一种三氮唑类似物化合物及其制备方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL103558A0 (en) * 1991-10-30 1993-03-15 Schering Corp Tri-substituted tetrahydrofuran antifungals
SK283035B6 (sk) * 1993-12-21 2003-02-04 Schering Corporation Tetrahydrofuránová zlúčenina, spôsob jej prípravy, jej farmaceuticky prijateľný ester, soľ a farmaceutický prostriedok
NZ278882A (en) * 1994-01-24 1997-06-24 Janssen Pharmaceutica Nv Piperazine-containing azole antifungal compounds

Also Published As

Publication number Publication date
EP0773941B1 (en) 2003-05-14
PL319635A1 (en) 1997-08-18
CN1161038A (zh) 1997-10-01
MX9701229A (es) 1997-05-31
SK27097A3 (en) 1997-09-10
AU5928096A (en) 1996-12-18
DE69628117D1 (de) 2003-06-18
EP0773941A1 (en) 1997-05-21
ATE240319T1 (de) 2003-05-15
CA2197672A1 (en) 1996-12-05
ES2199291T3 (es) 2004-02-16
TW357146B (en) 1999-05-01
CN1073109C (zh) 2001-10-17
CA2197672C (en) 2011-05-17
WO1996038443A1 (en) 1996-12-05
AR002751A1 (es) 1998-04-29
IL118464A0 (en) 1996-09-12
HK1008821A1 (en) 1999-05-21
HUP9701690A3 (en) 1998-04-28
DE69628117T2 (de) 2004-04-01
NO971218L (no) 1997-03-17
CZ59497A3 (en) 1997-08-13
HUP9701690A2 (hu) 1998-03-02
NZ309281A (en) 1998-07-28
IL118464A (en) 2000-08-13

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FC2A Withdrawal, rejection or dismissal of laid open patent application