NO964277L - Inhalator for tört pulver - Google Patents

Inhalator for tört pulver

Info

Publication number
NO964277L
NO964277L NO964277A NO964277A NO964277L NO 964277 L NO964277 L NO 964277L NO 964277 A NO964277 A NO 964277A NO 964277 A NO964277 A NO 964277A NO 964277 L NO964277 L NO 964277L
Authority
NO
Norway
Prior art keywords
dry powder
powder inhaler
housing
chamber
breathed
Prior art date
Application number
NO964277A
Other languages
English (en)
Other versions
NO964277D0 (no
Inventor
Mark B Mecikalski
David R Williams
David O Thueson
Original Assignee
Dura Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dura Pharma Inc filed Critical Dura Pharma Inc
Publication of NO964277D0 publication Critical patent/NO964277D0/no
Publication of NO964277L publication Critical patent/NO964277L/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/001Particle size control
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • A61M15/0005Details of inhalators; Constructional features thereof with means for agitating the medicament
    • A61M15/0006Details of inhalators; Constructional features thereof with means for agitating the medicament using rotating means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • A61M15/0005Details of inhalators; Constructional features thereof with means for agitating the medicament
    • A61M15/0006Details of inhalators; Constructional features thereof with means for agitating the medicament using rotating means
    • A61M15/0008Details of inhalators; Constructional features thereof with means for agitating the medicament using rotating means rotating by airflow
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • A61M15/0013Details of inhalators; Constructional features thereof with inhalation check valves
    • A61M15/0015Details of inhalators; Constructional features thereof with inhalation check valves located upstream of the dispenser, i.e. not traversed by the product
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • A61M15/0013Details of inhalators; Constructional features thereof with inhalation check valves
    • A61M15/0016Details of inhalators; Constructional features thereof with inhalation check valves located downstream of the dispenser, i.e. traversed by the product
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • A61M15/002Details of inhalators; Constructional features thereof with air flow regulating means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • A61M15/0021Mouthpieces therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033Details of the piercing or cutting means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0043Non-destructive separation of the package, e.g. peeling
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A61M15/0046Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
    • A61M15/0048Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged in a plane, e.g. on diskettes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0003Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/0015Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors
    • A61M2016/0018Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical
    • A61M2016/0021Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical with a proportional output signal, e.g. from a thermistor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/06Solids
    • A61M2202/064Powder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/33Controlling, regulating or measuring
    • A61M2205/3365Rotational speed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/82Internal energy supply devices
    • A61M2205/8206Internal energy supply devices battery-operated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00Characteristics of a physical parameter; associated device therefor
    • A61M2206/10Flow characteristics
    • A61M2206/16Rotating swirling helical flow, e.g. by tangential inflows

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Otolaryngology (AREA)
  • Medicinal Preparation (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nozzles (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Tørrpulverinhalator, med et hus (403) og et munnstykke (405). Et (orstøvningskammer (407) er dannet mellom en frontvegg (408) og en bakvegg (409) av huset (403). Et skovlhjul (411) er roterbart lagret på en tapp (413), for å rotere i forstøvningskammeret (407). Radiale innløp (425) forløper gjennom huset (403) og munner hovedsakelig tangentialt ut i forstøvningskammeret (407). En blisterpakning (421) på huset (403) avgir enkeltvise doser av en pulvermedisinblanding til forstøvningskammeret (407). Brukeren inhalerer fra munnstykket (405), hvilket bevirker at skovlhjulet (411) roterer og blander pulvermedisinen med luft, og blandingen pustes inn av brukeren.
NO964277A 1994-04-14 1996-10-09 Inhalator for tört pulver NO964277L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/227,559 US5492112A (en) 1991-05-20 1994-04-14 Dry powder inhaler
PCT/US1995/004598 WO1995028192A1 (en) 1994-04-14 1995-04-13 Dry powder inhaler

Publications (2)

Publication Number Publication Date
NO964277D0 NO964277D0 (no) 1996-10-09
NO964277L true NO964277L (no) 1996-10-09

Family

ID=22853574

Family Applications (1)

Application Number Title Priority Date Filing Date
NO964277A NO964277L (no) 1994-04-14 1996-10-09 Inhalator for tört pulver

Country Status (19)

Country Link
US (1) US5492112A (no)
EP (1) EP0755276A4 (no)
JP (1) JPH09511933A (no)
KR (1) KR100321814B1 (no)
CN (1) CN1150392A (no)
AU (1) AU681282B2 (no)
BG (1) BG62639B1 (no)
BR (1) BR9507390A (no)
CA (1) CA2187787A1 (no)
CZ (1) CZ285859B6 (no)
HU (1) HU220450B1 (no)
IS (1) IS4364A (no)
NO (1) NO964277L (no)
NZ (1) NZ284315A (no)
PL (1) PL179000B1 (no)
RO (1) RO119511B1 (no)
RU (1) RU2136322C1 (no)
UA (1) UA39134C2 (no)
WO (1) WO1995028192A1 (no)

Families Citing this family (125)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU213221B (en) * 1990-03-02 1997-03-28 Glaxo Group Ltd Inhalation device and medicine packet for device
TW197380B (no) * 1990-03-02 1993-01-01 Glaxo Group Ltd
TW360548B (en) * 1993-04-08 1999-06-11 Powderject Res Ltd Products for therapeutic use
EP0732952B1 (en) * 1993-12-18 2000-05-03 MERCK PATENT GmbH Powder inhalator
FR2725626A1 (fr) * 1994-10-18 1996-04-19 Sofab Dispositif pour l'inhalation de produits en poudre
US5921237A (en) * 1995-04-24 1999-07-13 Dura Pharmaceuticals, Inc. Dry powder inhaler
US5622166A (en) * 1995-04-24 1997-04-22 Dura Pharmaceuticals, Inc. Dry powder inhaler delivery system
US6428771B1 (en) * 1995-05-15 2002-08-06 Pharmaceutical Discovery Corporation Method for drug delivery to the pulmonary system
US6672304B1 (en) 1995-06-08 2004-01-06 Innovative Devices, Llc Inhalation actuated device for use with metered dose inhalers (MDIs)
DE19523516C1 (de) * 1995-06-30 1996-10-31 Asta Medica Ag Inhalator zum Verabreichen von Medikamenten aus Blisterpackungen
FR2738152B1 (fr) * 1995-09-04 1998-01-23 Tebro Dispositif de pre-dosage de produit pulverulent pour un distributeur de produit
WO1997025086A2 (en) * 1996-01-03 1997-07-17 Glaxo Group Limited Inhalation device
AU724503B2 (en) * 1996-04-29 2000-09-21 Dura Pharmaceuticals, Inc. Methods of dry powder inhalation
US5794613A (en) * 1997-01-09 1998-08-18 Sepracor, Inc. Multiple-dose dispenser for dry powder inhalers
SE9700940D0 (sv) * 1997-03-14 1997-03-14 Astra Ab Powder inhaler IV
US6006747A (en) * 1997-03-20 1999-12-28 Dura Pharmaceuticals, Inc. Dry powder inhaler
US6237590B1 (en) * 1997-09-18 2001-05-29 Delsys Pharmaceutical Corporation Dry powder delivery system apparatus
US6237591B1 (en) 1998-11-02 2001-05-29 Dura Pharmaceuticals, Inc. Turbine dry powder inhaler
US6116238A (en) * 1997-12-02 2000-09-12 Dura Pharmaceuticals, Inc. Dry powder inhaler
UA73924C2 (en) * 1998-10-09 2005-10-17 Nektar Therapeutics Device for delivering active agent formulation to lungs of human patient
WO2000036915A1 (en) 1998-12-22 2000-06-29 The University Of North Carolina At Chapel Hill Compounds and methods for the treatment of airway diseases and for the delivery of airway drugs
EP2280020B1 (en) * 1999-06-29 2016-02-17 MannKind Corporation Pharmaceutical formulations comprising a peptide complexed with a diketopiperazine
US9006175B2 (en) * 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
US7464706B2 (en) 1999-07-23 2008-12-16 Mannkind Corporation Unit dose cartridge and dry powder inhaler
US7305986B1 (en) * 1999-07-23 2007-12-11 Mannkind Corporation Unit dose capsules for use in a dry powder inhaler
US20010035184A1 (en) * 1999-12-17 2001-11-01 Carlos Schuler Systems and methods for treating packaged powders
US6651655B1 (en) 2000-01-18 2003-11-25 Quadrant Technologies Limited Inhaled vaccines
US6427688B1 (en) 2000-02-01 2002-08-06 Dura Pharmaceuticals, Icn. Dry powder inhaler
US6637430B1 (en) 2000-06-16 2003-10-28 Ponwell Enterprises Limited Respiratory delivery system with power/medicament recharge assembly
US7080644B2 (en) * 2000-06-28 2006-07-25 Microdose Technologies, Inc. Packaging and delivery of pharmaceuticals and drugs
JP2004505730A (ja) * 2000-08-15 2004-02-26 ユニバーシティ オブ ケンタッキー リサーチ ファウンデーション プログラム可能多用量鼻腔内薬物送達デバイス
GB0111330D0 (en) 2001-05-10 2001-07-04 Innovata Biomed Ltd Device
US8061006B2 (en) 2001-07-26 2011-11-22 Powderject Research Limited Particle cassette, method and kit therefor
US20030168057A1 (en) * 2001-12-14 2003-09-11 Inhale Therapeutic Systems, Inc. Electronically controllable aerosol delivery
ATE385193T1 (de) 2002-03-20 2008-02-15 Mannkind Corp Inhalationsgerät
JP2005533013A (ja) * 2002-04-19 2005-11-04 イスム リサーチ ディベロップメント カンパニー オブ ザ ヘブライ ユニバーシティ オブ エルサレム 一酸化窒素供与基および反応性酸素種捕捉基を含有するβ作用薬化合物、ならびに呼吸障害の治療における該化合物の使用
WO2004037843A2 (en) * 2002-10-25 2004-05-06 Yissum Research Development Company Of The Hebrew University Of Jerusalem Steroid compounds comprising superoxide dismutase mimic groups and nitric oxide donor groups, and their use in the preparation of medicaments
US7284553B2 (en) * 2002-12-12 2007-10-23 Boehringer Ingelheim Pharma Gmbh & Co. Kg Powder inhaler comprising a chamber for a capsule for taking up a non-returnable capsule being filled with an active ingredient
EP1488819A1 (en) 2003-06-16 2004-12-22 Rijksuniversiteit te Groningen Dry powder inhaler and method for pulmonary inhalation of dry powder
JP4805824B2 (ja) 2003-08-18 2011-11-02 パリオン・サイエンシィズ・インコーポレーテッド キャップ化ピラジノイルグアニジンナトリウムチャネルブロッカー
JP4445966B2 (ja) * 2003-09-24 2010-04-07 メディ−ストリーム プロプライエタリィ リミティッド 薬物ホルダー
AU2004273547B2 (en) * 2003-09-24 2006-07-06 Tianda Pharmaceuticals (Australia) Pty Ltd Medication holder
US7338171B2 (en) * 2003-10-27 2008-03-04 Jen-Chuen Hsieh Method and apparatus for visual drive control
US20070221218A1 (en) * 2003-10-27 2007-09-27 Warden Jeffrey A Dry Powder Drug Containment System Packages with Tabs, Inhalers and Associated Methods
US8147426B2 (en) * 2003-12-31 2012-04-03 Nipro Diagnostics, Inc. Integrated diagnostic test system
EP1708738B1 (en) * 2004-01-12 2016-05-04 MannKind Corporation A method of reducing serum proinsulin levels in type 2 diabetics
EP1747791B1 (en) * 2004-02-19 2012-07-25 Akihiko Miyamoto Asthma preparation inhaler auxiliary device with reed
US20080248999A1 (en) * 2007-04-04 2008-10-09 Biodel Inc. Amylin formulations
DK2319500T3 (da) * 2004-03-12 2013-02-04 Biodel Inc Hurtigtvirkende sammensætninger til afgivelse af lægemiddel
US20080090753A1 (en) 2004-03-12 2008-04-17 Biodel, Inc. Rapid Acting Injectable Insulin Compositions
WO2005102058A2 (en) * 2004-04-23 2005-11-03 Mystic Pharmaceuticals, Inc. Multiple unit dose drug delivery system
DE102004022796A1 (de) * 2004-05-08 2005-12-01 Arndt Muhle Inhalationsgerät
CN101010305B (zh) 2004-08-20 2010-08-11 曼金德公司 二酮哌嗪合成的催化反应
DK1791542T3 (en) 2004-08-23 2015-06-15 Mannkind Corp Diketopiperazinsalte for pharmaceutical delivery
JP2006130143A (ja) * 2004-11-08 2006-05-25 Hitachi Ltd 吸入式投薬器及び薬剤カートリッジ
WO2006051300A1 (en) * 2004-11-10 2006-05-18 Cipla Limited Inhaler
FR2877925B1 (fr) * 2004-11-16 2008-09-19 Valois Sas Dispositif de distribution de produit fluide.
GB0427858D0 (en) * 2004-12-20 2005-01-19 Glaxo Group Ltd Manifold for use in medicament dispenser
GB0427856D0 (en) * 2004-12-20 2005-01-19 Glaxo Group Ltd Maniflod for use in medicament dispenser
GB0427853D0 (en) * 2004-12-20 2005-01-19 Glaxo Group Ltd Manifold for use in medicament dispenser
US20070023042A1 (en) * 2005-07-28 2007-02-01 Lee Lanny R Demand free air flow inhalator
MX358592B (es) 2005-09-14 2018-08-27 Mannkind Corp Método para formulación de fármaco basado en el aumento de la afinidad de superficies de micropartículas cristalinas hacia agentes activos.
WO2007041481A1 (en) * 2005-09-29 2007-04-12 Biodel, Inc. Rapid acting and prolonged acting insulin preparations
US7713929B2 (en) 2006-04-12 2010-05-11 Biodel Inc. Rapid acting and long acting insulin combination formulations
US8084420B2 (en) * 2005-09-29 2011-12-27 Biodel Inc. Rapid acting and long acting insulin combination formulations
AR058290A1 (es) * 2005-12-12 2008-01-30 Glaxo Group Ltd Dispensador de medicamento
AR058289A1 (es) * 2005-12-12 2008-01-30 Glaxo Group Ltd Colector para ser usado en dispensador de medicamento
RU2403059C2 (ru) 2006-02-22 2010-11-10 Маннкайнд Корпорейшн Способ улучшения фармацевтических свойств микрочастиц, содержащих дикетопиперазин и активный агент
JP2009528295A (ja) 2006-02-24 2009-08-06 ライジェル ファーマシューティカルズ, インコーポレイテッド Jak経路の阻害のための組成物および方法
US8037880B2 (en) 2006-04-07 2011-10-18 The University Of Western Ontario Dry powder inhaler
JP2009533471A (ja) * 2006-04-12 2009-09-17 バイオデル, インコーポレイテッド 即効型および長時間作用型組合せインスリン製剤
EP1844808A1 (de) * 2006-04-13 2007-10-17 BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG Medikamenten-Ausgabevorrichtung
GR1005620B (el) * 2006-05-09 2007-09-03 Βελτιωση συσκευης εισπνοων ξηρης σκονης
FR2909644B1 (fr) * 2006-12-11 2011-03-04 Valois Sas Dispositif de distribution de produit fluide
US20080163610A1 (en) * 2007-01-05 2008-07-10 Matthew Thomas Baird Method and system for regenerating exhaust system filtering and catalyst components using variable high engine idle
BRPI0806474A2 (pt) 2007-01-09 2011-09-27 Mystic Pharmaceuticals Inc dispositivos de cartucho intranasal
WO2008144439A1 (en) 2007-05-16 2008-11-27 Mystic Pharmaceuticals, Inc. Combination unit dose dispensing containers
US8683995B2 (en) 2007-05-16 2014-04-01 Mystic Pharmaceuticals, Inc. Dose dispensing containers
US9248076B2 (en) 2007-05-16 2016-02-02 Mystic Pharmaceuticals, Inc. Dose dispensing containers
CA2699634C (en) * 2007-09-14 2015-06-09 Mystic Pharmaceuticals, Inc. Deep draw container forming method
US8785396B2 (en) 2007-10-24 2014-07-22 Mannkind Corporation Method and composition for treating migraines
EP2234644B1 (en) * 2008-01-04 2013-07-31 Biodel, Inc. Insulin formulations for insulin release as a function of tissue glucose levels
KR101654549B1 (ko) 2008-02-26 2016-09-07 패리온 사이언스 인코퍼레이티드 다중방향족 나트륨 채널 차단제
PT2254629E (pt) * 2008-03-27 2016-03-02 Mannkind Corp Um sistema de inalação de pó seco
KR101548092B1 (ko) 2008-06-13 2015-08-27 맨카인드 코포레이션 건조 분말 흡입기 및 약물 투여 시스템
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
ES2421385T3 (es) 2008-06-20 2013-09-02 Mannkind Corp Aparato interactivo y procedimiento para establecer el perfil, en tiempo real, de esfuerzos de inhalación
TWI532497B (zh) 2008-08-11 2016-05-11 曼凱公司 超快起作用胰島素之用途
JP5632848B2 (ja) * 2008-10-08 2014-11-26 アストラゼネカ・アクチエボラーグAstrazeneca Aktiebolag カバーの動作にリンクしてインデックス動作を行う吸入器
US8919341B2 (en) 2008-12-03 2014-12-30 Boehringer Ingelheim International Gmbh Inhaler
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
PE20110924A1 (es) 2009-01-23 2011-12-24 Rigel Pharmaceuticals Inc Derivados de 2, 4-diamino-pirimidina n2, n4-disustituidos como inhibidores de jak3
US9060927B2 (en) * 2009-03-03 2015-06-23 Biodel Inc. Insulin formulations for rapid uptake
EP2676695A3 (en) 2009-03-11 2017-03-01 MannKind Corporation Apparatus, system and method for measuring resistance of an inhaler
WO2010144789A2 (en) 2009-06-12 2010-12-16 Mannkind Corporation Diketopiperazine microparticles with defined specific surface areas
JP5784622B2 (ja) 2009-11-03 2015-09-24 マンカインド コーポレ−ション 吸入活動をシミュレートするための装置及び方法
CN105381524A (zh) * 2010-01-05 2016-03-09 微剂量治疗技术公司 吸入设备和方法
AU2011210352A1 (en) 2010-01-26 2012-08-09 Radikal Therapeutics Inc. Compositions and methods for prevention and treatment of pulmonary hypertension
CN102985125A (zh) 2010-06-21 2013-03-20 曼金德公司 干粉药物输送系统和方法
RU2453392C1 (ru) * 2010-10-19 2012-06-20 Виктор Евгеньевич Серебряков Способ литья цепи по газифицируемым моделям
CA2826410A1 (en) * 2010-11-29 2012-06-07 Sanofi-Aventis Deutschland Gmbh Medicated module for an inhaler
BR112013024021A2 (pt) * 2011-03-21 2016-12-06 Simplified Solutions Sweden Ab inalador para substâncias em forma de pó
JP6133270B2 (ja) 2011-04-01 2017-05-24 マンカインド コーポレイション 薬剤カートリッジのためのブリスター包装
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
CN103687488B (zh) 2011-06-27 2015-06-10 帕里昂科学公司 化学和代谢稳定的具有钠通道阻滞剂活性的二肽
JP6018640B2 (ja) 2011-10-24 2016-11-02 マンカインド コーポレイション 疼痛を緩和するのに有効な鎮痛組成物並びに当該組成物を含む乾燥粉末及び乾燥粉末薬剤輸送システム
CA2865504A1 (en) 2012-03-23 2013-09-26 Oxigene, Inc. Compositions and methods for inhibition of cathepsins
RU2650035C2 (ru) 2012-07-12 2018-04-06 Маннкайнд Корпорейшн Системы и способы доставки сухих порошковых лекарств
EP2911690A1 (en) 2012-10-26 2015-09-02 MannKind Corporation Inhalable influenza vaccine compositions and methods
EP3587404B1 (en) 2013-03-15 2022-07-13 MannKind Corporation Microcrystalline diketopiperazine compositions, methods for preparation and use thereof
MX2020009878A (es) 2013-07-18 2022-07-27 Mannkind Corp Composiciones farmaceuticas en polvo seco estables al calor y metodos.
EP3030294B1 (en) 2013-08-05 2020-10-07 MannKind Corporation Insufflation apparatus
AU2014351852B2 (en) * 2013-11-20 2019-07-18 Transunit Ab A turbine ventilator system and method
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
CN105709349A (zh) * 2016-04-24 2016-06-29 唐淑华 一种吸气鼻罩
GB201721447D0 (en) * 2017-12-20 2018-01-31 British American Tobacco Investments Ltd Electronic aerosol provision system
GB201721470D0 (en) 2017-12-20 2018-01-31 British American Tobacco Investments Ltd Electronic aerosol provision system
GB201721477D0 (en) 2017-12-20 2018-01-31 British American Tobacco Investments Ltd Electronic aerosol provision system
DE102019109079B4 (de) * 2018-07-03 2020-06-04 MO GmbH & Co. KG Aerosol-Dispersionseinrichtung
US20220000880A1 (en) 2018-11-01 2022-01-06 Rigel Pharmaceuticals, Inc. Method and composition embodiments for treating acute myeloid leukemia
WO2020243612A1 (en) 2019-05-29 2020-12-03 Rigel Pharmaceuticals, Inc. Method of preventing and treating thrombosis
WO2021026451A1 (en) 2019-08-08 2021-02-11 Rigel Pharmaceuticals, Inc. Compounds and method for treating cytokine release syndrome
EP4013420B1 (en) 2019-08-14 2023-11-01 Rigel Pharmaceuticals, Inc. Method of blocking or ameliorating cytokine release syndrome
TW202346291A (zh) 2022-03-23 2023-12-01 美商雷傑製藥公司 作為irak抑制劑的嘧啶—2—基—吡唑化合物

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3669113A (en) * 1966-03-07 1972-06-13 Fisons Ltd Inhalation device
GB1182779A (en) * 1966-09-17 1970-03-04 Fisons Pharmaceuticals Ltd Inhalation Device
US3507277A (en) * 1966-09-17 1970-04-21 Fisons Pharmaceuticals Ltd Inhalation device
GB1268051A (en) * 1968-06-07 1972-03-22 Fisons Pharmaceuticals Ltd Inhalation device
US3812853A (en) * 1971-11-17 1974-05-28 P Crain Apparatus for applying medication or the like to human nasal passages
US3971377A (en) * 1974-06-10 1976-07-27 Alza Corporation Medicament dispensing process for inhalation therapy
US3948264A (en) * 1975-05-21 1976-04-06 Mead Johnson & Company Inhalation device
US4147166A (en) * 1977-05-02 1979-04-03 American Cyanamid Company Oral inhalator powder dispenser
BR8007911A (pt) * 1979-12-06 1981-06-16 Glaxo Group Ltd Inalador aperfeicoado
US4452239A (en) * 1980-03-25 1984-06-05 Hilal Malem Medical nebulizing apparatus
ES8206980A1 (es) * 1980-10-30 1982-09-01 Riker Laboratories Inc Un dispositivo para facilitar la inhalacion oral de medica- mentos en forma de polvo
DE3274065D1 (de) * 1981-07-08 1986-12-11 Draco Ab Powder inhalator
US4778054A (en) * 1982-10-08 1988-10-18 Glaxo Group Limited Pack for administering medicaments to patients
AT396872B (de) * 1985-07-30 1993-12-27 Glaxo Group Ltd Gerät zur verabreichung von medikamenten in pulverform
US4739754A (en) * 1986-05-06 1988-04-26 Shaner William T Suction resistant inhalator
WO1991001884A1 (en) * 1989-07-27 1991-02-21 The Upjohn Company Combined ink laser printing of tablets
IT1237118B (it) * 1989-10-27 1993-05-18 Miat Spa Inalatore multidose per farmaci in polvere.
IT1240750B (it) * 1990-04-12 1993-12-17 Chiesi Farma Spa Dispositivo per la somministrazione di sostanze medicamentose in polvere
WO1994006498A1 (en) * 1992-09-23 1994-03-31 Fisons Plc Inhalation device

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UA39134C2 (uk) 2001-06-15
JPH09511933A (ja) 1997-12-02
EP0755276A1 (en) 1997-01-29
US5492112A (en) 1996-02-20
CZ285859B6 (cs) 1999-11-17
NO964277D0 (no) 1996-10-09
CZ298096A3 (en) 1997-03-12
IS4364A (is) 1996-10-29
BG62639B1 (bg) 2000-04-28
CN1150392A (zh) 1997-05-21
PL179000B1 (pl) 2000-07-31
KR100321814B1 (ko) 2002-10-12
EP0755276A4 (en) 1998-04-01
AU681282B2 (en) 1997-08-21
HUT74899A (en) 1997-02-28
PL316903A1 (en) 1997-02-17
NZ284315A (en) 1997-12-19
RU2136322C1 (ru) 1999-09-10
CA2187787A1 (en) 1995-10-26
AU2289995A (en) 1995-11-10
BG100894A (en) 1997-07-31
HU9602818D0 (en) 1996-12-30
HU220450B1 (hu) 2002-02-28
BR9507390A (pt) 1997-09-16

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