NO963983D0 - Luciferaser - Google Patents

Luciferaser

Info

Publication number
NO963983D0
NO963983D0 NO963983A NO963983A NO963983D0 NO 963983 D0 NO963983 D0 NO 963983D0 NO 963983 A NO963983 A NO 963983A NO 963983 A NO963983 A NO 963983A NO 963983 D0 NO963983 D0 NO 963983D0
Authority
NO
Norway
Prior art keywords
luciferase
preparation
retains
room temperature
stored
Prior art date
Application number
NO963983A
Other languages
English (en)
Other versions
NO963983L (no
NO319706B1 (no
Inventor
Christopher Robin Lowe
Peter John White
James Augustus Henry Murray
David James Squirrel
Original Assignee
Secr Defence Brit
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9405750A external-priority patent/GB9405750D0/en
Application filed by Secr Defence Brit filed Critical Secr Defence Brit
Publication of NO963983L publication Critical patent/NO963983L/no
Publication of NO963983D0 publication Critical patent/NO963983D0/no
Publication of NO319706B1 publication Critical patent/NO319706B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0069—Oxidoreductases (1.) acting on single donors with incorporation of molecular oxygen, i.e. oxygenases (1.13)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y113/00—Oxidoreductases acting on single donors with incorporation of molecular oxygen (oxygenases) (1.13)
    • C12Y113/12—Oxidoreductases acting on single donors with incorporation of molecular oxygen (oxygenases) (1.13) with incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)(1.13.12)
    • C12Y113/12007—Photinus-luciferin 4-monooxygenase (ATP-hydrolysing) (1.13.12.7), i.e. firefly-luciferase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
NO19963983A 1994-03-23 1996-09-23 Protein med luciferaseaktivitet, DNA, vektor, celle, provekit samt analysemetode. NO319706B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9405750A GB9405750D0 (en) 1994-03-23 1994-03-23 Luciferases
GBGB9501170.6A GB9501170D0 (en) 1994-03-23 1995-01-20 Luciferases
PCT/GB1995/000629 WO1995025798A1 (en) 1994-03-23 1995-03-22 Luciferases

Publications (3)

Publication Number Publication Date
NO963983L NO963983L (no) 1996-09-23
NO963983D0 true NO963983D0 (no) 1996-09-23
NO319706B1 NO319706B1 (no) 2005-09-05

Family

ID=26304561

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19963983A NO319706B1 (no) 1994-03-23 1996-09-23 Protein med luciferaseaktivitet, DNA, vektor, celle, provekit samt analysemetode.

Country Status (17)

Country Link
US (1) US6132983A (no)
EP (2) EP0751996B1 (no)
JP (3) JP4490508B2 (no)
KR (1) KR100392020B1 (no)
CN (1) CN100387720C (no)
AT (1) ATE230800T1 (no)
AU (1) AU697883B2 (no)
BR (1) BR9507140A (no)
CA (1) CA2186144C (no)
DE (1) DE69529337T2 (no)
DK (1) DK0751996T3 (no)
ES (1) ES2185697T3 (no)
FI (1) FI120096B (no)
GB (1) GB9501170D0 (no)
NO (1) NO319706B1 (no)
RU (1) RU2192467C2 (no)
WO (1) WO1995025798A1 (no)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9501170D0 (en) * 1994-03-23 1995-03-08 Secr Defence Luciferases
WO1996022376A1 (en) * 1995-01-20 1996-07-25 The Secretary Of State For Defence Mutant luciferases
GB2311525B (en) * 1995-01-20 1998-11-11 Secr Defence Mutant Luciferases
GB9707486D0 (en) 1997-04-11 1997-05-28 Secr Defence Enzyme assays
JP4537573B2 (ja) * 1997-09-19 2010-09-01 プロメガ・コーポレイシヨン 熱安定ルシフェラーゼと生産方法
US6602677B1 (en) 1997-09-19 2003-08-05 Promega Corporation Thermostable luciferases and methods of production
GB9722481D0 (en) * 1997-10-25 1997-12-24 Secr Defence Expression system
US6117643A (en) * 1997-11-25 2000-09-12 Ut Battelle, Llc Bioluminescent bioreporter integrated circuit
DE69938293T2 (de) * 1998-03-27 2009-03-12 Bruce J. Beverly Hills Bryan Luciferase, gfp fluoreszenzproteine, kodierende nukleinsaüre und ihre verwendung in der diagnose
EP1925320A3 (en) 1998-03-27 2008-09-03 Prolume, Ltd. Luciferases, fluorescent proteins, nucleic acids encoding the luciferases and fluorescent proteins and the use thereof in diagnostics
GB9823468D0 (en) 1998-10-28 1998-12-23 Secr Defence Novel enzyme
GB9925161D0 (en) * 1999-10-26 1999-12-22 Secr Defence Novel enzyme
AU772485C (en) * 1999-10-26 2004-11-18 Promega Corporation Novel enzyme
US7879540B1 (en) 2000-08-24 2011-02-01 Promega Corporation Synthetic nucleic acid molecule compositions and methods of preparation
US20020073441A1 (en) 2000-12-13 2002-06-13 Ross Brian D. Compositions and methods for detecting proteolytic activity
GB0111275D0 (en) 2001-05-09 2001-06-27 Secr Defence Analytical method and kit
WO2003072720A2 (en) 2002-02-21 2003-09-04 Medimmune Vaccines, Inc. Recombinant parainfluenza virus expression systems and vaccines comprising heterologous antigens derived from metapneumovirus
AU2003301883A1 (en) * 2002-10-30 2004-06-07 University Of Tennessee Research Foundation Modified luciferase nucleic acids and methods of use
US7413874B2 (en) 2002-12-09 2008-08-19 University Of Miami Nucleic acid encoding fluorescent proteins from aquatic species
WO2004087069A2 (en) 2003-03-27 2004-10-14 Ptc Therapeutics, Inc. METHODS OF IDENTIFYING COMPOUNDS THAT TARGET tRNA SPLICING ENDONUCLEASE AND USES OF SAID COMPOUNDS AS ANTI-PROLIFERATIVE AGENTS
EP1613160A4 (en) 2003-03-27 2008-01-02 Ptc Therapeutics Inc VIEWING ENZYMES OF THE TRNA-SPLICE PATH TO IDENTIFY ANTIFUNGAL AND / OR PROLIFERATION-INHIBITING MOLECULES
WO2004099421A1 (ja) * 2003-05-06 2004-11-18 National Institute Of Advanced Industrial Science And Technology マルチ遺伝子転写活性測定システム
US7728118B2 (en) 2004-09-17 2010-06-01 Promega Corporation Synthetic nucleic acid molecule compositions and methods of preparation
GB0517005D0 (en) 2005-08-19 2005-09-28 Enigma Diagnostics Ltd Analytical method and kit
US7807429B2 (en) * 2006-02-13 2010-10-05 Connecticut College Isolated luciferase gene of L. italica
JP5188771B2 (ja) 2007-09-26 2013-04-24 株式会社日立製作所 変異型ホタルルシフェラーゼ
JP5753083B2 (ja) * 2008-07-22 2015-07-22 プロメガ コーポレイションＰｒｏｍｅｇａ Ｃｏｒｐｏｒａｔｉｏｎ Ａｄｐ検出に基づく発光ホスホトランスフェラーゼまたはａｔｐヒドロラーゼのアッセイ法
JP2010081908A (ja) * 2008-10-02 2010-04-15 Hitachi Ltd 変異型のホタルルシフェラーゼ
JP2011120559A (ja) 2008-12-26 2011-06-23 Kikkoman Corp ホタルルシフェラーゼ、その遺伝子、およびホタルルシフェラーゼの製造法
US20110076706A1 (en) * 2009-06-26 2011-03-31 Genprime, Inc. Methods and kits for the rapid detection of microorganisms
US9487520B2 (en) 2010-11-02 2016-11-08 Promega Corporation Coelenterazine derivatives and methods of using same
WO2012061530A2 (en) 2010-11-02 2012-05-10 Promega Corporation Oplophorus-derived luciferases, novel coelenterazine substrates, and methods of use
CN105121653B (zh) 2013-02-22 2020-01-24 普洛麦格公司 用于荧光素酶和核苷磷酸的发光检测的稳定制剂
JP6703484B2 (ja) 2014-01-29 2020-06-03 プロメガ コーポレイションＰｒｏｍｅｇａ Ｃｏｒｐｏｒａｔｉｏｎ 細胞による取り込み測定のための、標識用試薬としての、キノンでマスクされたプローブ
JP6588917B2 (ja) 2014-01-29 2019-10-09 プロメガ コーポレイションＰｒｏｍｅｇａ Ｃｏｒｐｏｒａｔｉｏｎ 生細胞への適用のためのプロ基質
EP3191600A1 (en) 2014-09-11 2017-07-19 Promega Corporation Luciferase sequences utilizing infrared-emitting substrates to produce enhanced luminescence
WO2016057084A1 (en) 2014-10-08 2016-04-14 Promega Corporation Bioluminescent succinate detection assay
CN105200022B (zh) * 2015-11-03 2018-11-16 南京工业大学 萤火虫荧光素酶热稳定性改造的方法
JP6349003B1 (ja) 2017-03-17 2018-06-27 東洋ビーネット株式会社 耐熱性ルシフェラーゼ
JPWO2021162123A1 (no) 2020-02-14 2021-08-19
CN114015664B (zh) * 2021-12-06 2023-07-21 郑州伊美诺生物技术有限公司 荧光素酶突变体及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3048466B2 (ja) * 1991-06-27 2000-06-05 キッコーマン株式会社 耐熱性ホタルルシフェラーゼ、耐熱性ホタルルシフェラーゼ遺伝子、新規な組み換え体ｄｎａ、及び耐熱性ホタルルシフェラーゼの製造法
US5229285A (en) * 1991-06-27 1993-07-20 Kikkoman Corporation Thermostable luciferase of firefly, thermostable luciferase gene of firefly, novel recombinant dna, and process for the preparation of thermostable luciferase of firefly
DE4124495A1 (de) * 1991-07-24 1993-01-28 Happich Gmbh Gebr Fenstereinfassrahmen, insbesondere fuer fahrzeuge
GB9501170D0 (en) * 1994-03-23 1995-03-08 Secr Defence Luciferases

Also Published As

Publication number Publication date
KR970702369A (ko) 1997-05-13
EP1281762B1 (en) 2014-12-31
FI963741A (fi) 1996-11-20
ES2185697T3 (es) 2003-05-01
DE69529337T2 (de) 2003-10-16
KR100392020B1 (ko) 2003-10-22
FI120096B (fi) 2009-06-30
CA2186144A1 (en) 1995-09-28
CA2186144C (en) 2009-12-22
GB9501170D0 (en) 1995-03-08
NO963983L (no) 1996-09-23
JP2006271393A (ja) 2006-10-12
EP1281762A2 (en) 2003-02-05
CN100387720C (zh) 2008-05-14
AU1954595A (en) 1995-10-09
JP4490508B2 (ja) 2010-06-30
US6132983A (en) 2000-10-17
EP0751996B1 (en) 2003-01-08
DE69529337D1 (de) 2003-02-13
EP0751996A1 (en) 1997-01-08
FI963741A0 (fi) 1996-09-20
JPH09510610A (ja) 1997-10-28
JP2010088440A (ja) 2010-04-22
WO1995025798A1 (en) 1995-09-28
RU2192467C2 (ru) 2002-11-10
AU697883B2 (en) 1998-10-22
CN1149318A (zh) 1997-05-07
EP1281762A3 (en) 2003-11-05
BR9507140A (pt) 1997-09-30
DK0751996T3 (da) 2003-02-24
ATE230800T1 (de) 2003-01-15
NO319706B1 (no) 2005-09-05

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Legal Events

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