NO963776L - (4,4-Difluorbut-3-enyltio)-substituerte heterocykliske eller karbocykliske ringforbindelser med disinfiserende virkning - Google Patents

(4,4-Difluorbut-3-enyltio)-substituerte heterocykliske eller karbocykliske ringforbindelser med disinfiserende virkning

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Publication number
NO963776L
NO963776L NO963776A NO963776A NO963776L NO 963776 L NO963776 L NO 963776L NO 963776 A NO963776 A NO 963776A NO 963776 A NO963776 A NO 963776A NO 963776 L NO963776 L NO 963776L
Authority
NO
Norway
Prior art keywords
optionally substituted
haloalkyl
hydroxy
alkyl
alkylsor7
Prior art date
Application number
NO963776A
Other languages
English (en)
Other versions
NO963776D0 (no
Inventor
Michael Turnbull
Harjinder Singh Bansal
Alison Mary Smith
Roger Salmon
Steven Fitzjohn
Christopher Richard Ay Godfrey
Matthew Brian Hotson
Nan Catherine Sillars
Alan John Dowling
Original Assignee
Zeneca Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9404718A external-priority patent/GB9404718D0/en
Priority claimed from GB9404720A external-priority patent/GB9404720D0/en
Priority claimed from GB9404721A external-priority patent/GB9404721D0/en
Priority claimed from GB9404719A external-priority patent/GB9404719D0/en
Priority claimed from GB9404716A external-priority patent/GB9404716D0/en
Priority claimed from GB9404717A external-priority patent/GB9404717D0/en
Priority claimed from GBGB9500521.1A external-priority patent/GB9500521D0/en
Application filed by Zeneca Ltd filed Critical Zeneca Ltd
Publication of NO963776D0 publication Critical patent/NO963776D0/no
Publication of NO963776L publication Critical patent/NO963776L/no

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/70—Sulfur atoms
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    • A01N33/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
    • A01N33/16—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds containing nitrogen-to-oxygen bonds
    • A01N33/18—Nitro compounds
    • A01N33/20—Nitro compounds containing oxygen or sulfur attached to the carbon skeleton containing the nitro group
    • A01N33/22—Nitro compounds containing oxygen or sulfur attached to the carbon skeleton containing the nitro group having at least one oxygen or sulfur atom and at least one nitro group directly attached to the same aromatic ring system
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    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
    • A01N43/04—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
    • A01N43/06—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom five-membered rings
    • A01N43/08—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom five-membered rings with oxygen as the ring hetero atom
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    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
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    • A01N43/04—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
    • A01N43/06—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom five-membered rings
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    • A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
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    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
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    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
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    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles
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    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
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    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
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    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
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    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
    • A01N43/66—1,3,5-Triazines, not hydrogenated and not substituted at the ring nitrogen atoms
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    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
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    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/713—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with four or more nitrogen atoms as the only ring hetero atoms
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    • A01N43/74—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,3
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    • A01N43/80—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,2
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    • A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
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    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/01—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and halogen atoms, or nitro or nitroso groups bound to the same carbon skeleton
    • C07C323/09—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and halogen atoms, or nitro or nitroso groups bound to the same carbon skeleton having sulfur atoms of thio groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
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    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/70—Sulfur atoms
    • C07D213/71—Sulfur atoms to which a second hetero atom is attached
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    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
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    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
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    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

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Abstract

Forbindelse med formel (I), eller et salt derav, hvor n er O, l eller 2, og R er en gruppe med formel (II) til (XXI), hvor S (O) CH2CH2CH=CF2 -gruppen er i det minste en av R1 (når den er bundet til et karbonatom) , R2, R3, R4, R5 eller R6, R1 (når den er bundet til et karbonatom), R2, R3, R4, R5 og R6, hver, uavhengig, er hydrogen, eventuelt substituert alkyl, eventuelt substituert alkenyl, alkynyl, cykloalkyl, alkylcyk- loalkyl, alkoksy, alkenyloksy, alkynyloksy, hydroksyalkyl , alkoksyalkyl, eventuelt substituert aryl, eventuelt substi- tuert arylalkyl, eventuelt substituert heteroaryl, eventuelt substituert heteroarylalkyl, eventuelt substituert aryloksy, eventuelt substituert arylalkoksy, eventuelt substituert aryloksyalkyl , eventuelt substituert heteroaryloksy, eventuelt substituert heteroarylalkoksy, eventuelt substituert hetero- aryloksyalkyl, halogenalkyl, halogenalkenyl, halogenalkynyl, halogenalkoksy, halogenalkenyloksy, halogenalkynyloksy, halogen, hydroksy, cyano, nitro, -NR7R8, -NR7COR8, -NR7CSR8, -NR7S02R8, -N(S02R7) (S02R8) , -COR7, -CONR7R8, -alkylCONR7R8, -CR7NR8, -COOR7, -OCOR7, -SR7, -SOR7, -SO_R7, -alkylSR7, -alkylSOR7, -alkylSO2R7, -OSO2R7, -S02NR7R8 CSNR7R8, -SiR7R8R9, O2R, -OCH2CH2CO_R, -CONR7S02R8, -alkylCONR7S02R8, -NHCONR7R8, -NHCSNR7R8, eller et nærliggende par av R1, R2, R , R4, R5 og R6" når -"de sammen danner en kondensert 5- eller 6-leddet karbocyklisk eller heterocyklisk ring, R1 (når den er bundet til et nitrogenatom) er hydrogen, eventuelt substituert alkyl, cykloalkyl, alkyl- . cykloalkyl, hydroksyalkyl, alkoksyalkyl, eventuelt substituert aryl, eventuelt substituert arylalkyl, eventuelt substituert aryloksyalkyl, eventuelt substituert heteroaryl, eventuelt substituert heteroarylalkyl, eventuelt substituert heteroaryl- oksyalkyl, halogenalkyl, hydroksy, cyano, nitro, -NR R , -NR7COR8 -NR7CSR8, -NR7COOR8, -COR -NR7S02R8, -NfSO.R7} (SO-R8) , -CONR7R8, -alkylCONR7R8, -CR7NR8, -COOR7, -OCOR7, -SOR7, -SO2R7, -alkylSR7, -alkylSOR7, -alkylS02R7, -OSO-R7, -S02NR7R8 -CSNR7R8, "7 o 7 -SiR R°R', -SR7, -SOR7, -S02R7, OCH0CO.R7, -OCH0CH.CO,R7, -CONR7SO-R8, -alkylCONR7SO,R8, 7 fl 7 R 7 B 9 -NHCOR R eller -NHCSR R, og R , R og R er hver, uavhengig, hydrogen, eventuelt substituert alkyl, eventuelt substituert alkenyl, alkynyl, eventuelt substituert aryl eller eventuelt substituert arylalkyl, halogenalkyl, halogenalkenyl, halogen- alkynyl, halogen eller hydroksy.
NO963776A 1994-03-10 1996-09-09 (4,4-Difluorbut-3-enyltio)-substituerte heterocykliske eller karbocykliske ringforbindelser med disinfiserende virkning NO963776L (no)

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GB9404718A GB9404718D0 (en) 1994-03-10 1994-03-10 Aromatic and heterocyclic compounds
GB9404720A GB9404720D0 (en) 1994-03-10 1994-03-10 Heterocyclic compounds
GB9404721A GB9404721D0 (en) 1994-03-10 1994-03-10 Heterocyclic compounds
GB9404719A GB9404719D0 (en) 1994-03-10 1994-03-10 Heterocyclic compounds
GB9404716A GB9404716D0 (en) 1994-03-10 1994-03-10 Heterocyclic compounds
GB9404717A GB9404717D0 (en) 1994-03-10 1994-03-10 Heterocyclic compounds
GBGB9500521.1A GB9500521D0 (en) 1995-01-11 1995-01-11 Heterocyclic compounds

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RU2151147C1 (ru) 2000-06-20
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US5705516A (en) 1998-01-06
AP649A (en) 1998-05-29
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CZ285605B6 (cs) 1999-09-15
EE9600123A (et) 1997-04-15
NO963776D0 (no) 1996-09-09
US5952359A (en) 1999-09-14
PT749433E (pt) 2003-08-29
WO1995024403A1 (en) 1995-09-14
CA2182520A1 (en) 1995-09-14
LV11686B (en) 1997-06-20
BG100900A (en) 1997-07-31
RO116399B1 (ro) 2001-01-30
CN1143958A (zh) 1997-02-26
KR970701709A (ko) 1997-04-12
FI963539A0 (fi) 1996-09-09
KR100245904B1 (ko) 2000-04-01
IL112721A0 (en) 1995-05-26
EP0749433A1 (en) 1996-12-27
LV11686A (lv) 1997-02-20
AU685242B2 (en) 1998-01-15
AU1816495A (en) 1995-09-25
EP0749433B1 (en) 2003-05-07
JP3857722B2 (ja) 2006-12-13
JPH09510197A (ja) 1997-10-14
DE69530681D1 (de) 2003-06-12
BG62809B1 (bg) 2000-08-31
AP9600862A0 (en) 1996-10-31
HU215211B (hu) 1998-10-28
HUT74902A (en) 1997-02-28
ATE239714T1 (de) 2003-05-15
DK0749433T3 (da) 2003-09-01
UA44732C2 (uk) 2002-03-15
FI963539A (fi) 1996-09-09
DE69530681T2 (de) 2004-03-18
SK114896A3 (en) 1997-04-09
PL316175A1 (en) 1996-12-23
BR9507042A (pt) 1997-09-09
US5912243A (en) 1999-06-15
MX9603956A (es) 1997-07-31

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