NO963412L - Analogifremgangsmåte for fremstilling av terapeutisk virksomme kinoxalinforbindelser - Google Patents
Analogifremgangsmåte for fremstilling av terapeutisk virksomme kinoxalinforbindelserInfo
- Publication number
- NO963412L NO963412L NO963412A NO963412A NO963412L NO 963412 L NO963412 L NO 963412L NO 963412 A NO963412 A NO 963412A NO 963412 A NO963412 A NO 963412A NO 963412 L NO963412 L NO 963412L
- Authority
- NO
- Norway
- Prior art keywords
- alkyl
- halogen
- hydrogen
- compounds
- substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
- C07D241/40—Benzopyrazines
- C07D241/44—Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/50—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to ring nitrogen atoms
- C07D241/52—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Steroid Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK586287A DK586287D0 (da) | 1987-11-10 | 1987-11-10 | Quinoxalinforbindelser, deres fremstilling og anvendelse |
| DK142288A DK142288D0 (da) | 1988-03-16 | 1988-03-16 | Quinoxalinforbindelser, deres fremstilling og anvendelse |
| NO884729A NO179551C (no) | 1987-11-10 | 1988-10-24 | Analogifremgangsmåte for fremstilling av terapeutisk virksomme kinoxalinforbindelser |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO963412L true NO963412L (no) | 1989-05-11 |
| NO307252B1 NO307252B1 (no) | 2000-03-06 |
Family
ID=26065733
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO884729A NO179551C (no) | 1987-11-10 | 1988-10-24 | Analogifremgangsmåte for fremstilling av terapeutisk virksomme kinoxalinforbindelser |
| NO963412A NO307252B1 (no) | 1987-11-10 | 1996-08-15 | Analogifremgangsmåte for fremstilling av terapeutisk virksomme kinoxalinforbindelser |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO884729A NO179551C (no) | 1987-11-10 | 1988-10-24 | Analogifremgangsmåte for fremstilling av terapeutisk virksomme kinoxalinforbindelser |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US4948794A (no) |
| EP (1) | EP0315959B1 (no) |
| JP (1) | JP2721520B2 (no) |
| KR (1) | KR970011279B1 (no) |
| AT (1) | ATE102192T1 (no) |
| AU (1) | AU618766B2 (no) |
| CA (1) | CA1321587C (no) |
| DE (1) | DE3888093T2 (no) |
| ES (1) | ES2061606T3 (no) |
| FI (1) | FI100181B (no) |
| IE (1) | IE64320B1 (no) |
| IL (1) | IL88155A0 (no) |
| NO (2) | NO179551C (no) |
| NZ (1) | NZ226916A (no) |
| PH (1) | PH25103A (no) |
| PT (1) | PT88964B (no) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NO179551C (no) * | 1987-11-10 | 1996-10-30 | Novo Nordisk As | Analogifremgangsmåte for fremstilling av terapeutisk virksomme kinoxalinforbindelser |
| DK716188D0 (da) * | 1988-12-22 | 1988-12-22 | Ferrosan As | Quinoxalinforbindelser, deres fremstilling og anvendelse |
| DK715888D0 (da) * | 1988-12-22 | 1988-12-22 | Ferrosan As | Quinoxalinforbindelser, deres fremstilling og anvendelse |
| DK69790D0 (da) * | 1990-03-16 | 1990-03-16 | Novo Nordisk As | Heterocykliske forbindelser, deres fremstilling af anvendelse |
| JP2550456B2 (ja) * | 1990-11-06 | 1996-11-06 | 山之内製薬株式会社 | 縮合ピラジン誘導体 |
| PT99864B (pt) | 1990-12-21 | 1999-06-30 | Schering Ag | Processo para a preparacao de novas composicoes farmaceuticas contendo antagonistas de receptor de quisqualato |
| DK73091D0 (da) * | 1991-04-22 | 1991-04-22 | Novo Nordisk As | Quinoxalinforbindelser, deres fremstilling og anvendelse |
| US5153196A (en) * | 1991-06-05 | 1992-10-06 | Eli Lilly And Company | Excitatory amino acid receptor antagonists and methods for the use thereof |
| US5196421A (en) * | 1991-06-05 | 1993-03-23 | Eli Lilly And Company | Excitatory amino acid receptor antagonists in methods for the use thereof |
| DK177191D0 (da) * | 1991-10-23 | 1991-10-23 | Novo Nordisk As | Heterocyclic compounds and their preparation and use |
| PT101004B (pt) * | 1991-10-26 | 1999-10-29 | Schering Ag | Derivados da quinoxalina, processo para a sua preparacao e composicoes farmaceuticas que os contem |
| US6057304A (en) | 1992-10-26 | 2000-05-02 | Schering Aktiengesellschaft | Quinoxaline-phosphonic acid derivatives |
| DE4217952A1 (de) * | 1992-05-30 | 1993-12-02 | Basf Ag | Chinoxalin-2,3(1H,4H)-dione |
| WO1994000124A1 (en) * | 1992-06-22 | 1994-01-06 | Eckard Weber | Glycine receptor antagonists and the use thereof |
| FR2696466B1 (fr) * | 1992-10-02 | 1994-11-25 | Rhone Poulenc Rorer Sa | Dérivés de 5H,10H-imidazo[1,2-a]indeno[1,2-e]pyrazine-4-one, leur préparation et les médicaments les contenant. |
| DK12293D0 (da) * | 1993-02-02 | 1993-02-02 | Novo Nordisk As | Heterocykliske forbindelser og deres fremstilling og anvendelse |
| IL109397A0 (en) * | 1993-04-28 | 1994-07-31 | Schering Ag | Quinoxalinedione derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same |
| DE4314592A1 (de) * | 1993-04-28 | 1994-11-03 | Schering Ag | Benzo(f)chinoxalindionderivate, deren Herstellung und Verwendung in Arzneimitteln |
| US5631373A (en) * | 1993-11-05 | 1997-05-20 | State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon, Eugene Oregon | Alkyl, azido, alkoxy, and fluoro-substituted and fused quinoxalinediones |
| DE4340045A1 (de) * | 1993-11-24 | 1995-06-01 | Basf Ag | Neue Chinoxaline und Arzneimittel daraus |
| AU688459B2 (en) * | 1994-04-08 | 1998-03-12 | Shionogi & Co., Ltd. | Oxopyridinylquinoxaline derivative |
| DE4428152A1 (de) * | 1994-06-22 | 1996-01-04 | Basf Ag | Neue Amido-chinoxalindione, ihrer Herstellung und Verwendung |
| US5597922A (en) * | 1994-07-29 | 1997-01-28 | State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon | Glycine receptor antagonist pharmacophore |
| DE4436852A1 (de) * | 1994-10-14 | 1996-04-18 | Basf Ag | Pyrrolyl-tetrahydrobenzochinoxalindione, ihre Herstellung und Verwendung |
| DE19521058A1 (de) * | 1995-06-09 | 1996-12-12 | Basf Ag | Verfahren zur Herstellung von Aromaten enthaltenden Polyetherpolyolen |
| DE19545251A1 (de) * | 1995-11-24 | 1997-05-28 | Schering Ag | Neue Chinoxalindionderivate, deren Herstellung und Verwendung in Arzneimitteln |
| DE19624808A1 (de) | 1996-06-21 | 1998-01-02 | Basf Ag | Pyrrolylchinoxalindione, ihre Herstellung und Verwendung |
| PT934326E (pt) * | 1996-10-24 | 2006-08-31 | Novartis Ag | Acidos aminoalcanofosfonicos substituidos |
| US5922715A (en) * | 1997-02-18 | 1999-07-13 | American Home Products Corporation | 5-aminoalkoxy-1, 4-dihydroquinoxaline-2, 3-diones |
| EP0963372A1 (en) * | 1997-02-18 | 1999-12-15 | American Home Products Corporation | 5-aminoalkoxy-1,4-dihydroquinoxaline-2,3-diones being dopamine agonists |
| JP4707261B2 (ja) * | 2001-05-15 | 2011-06-22 | 日本エンバイロケミカルズ株式会社 | キノキサリン系化合物および工業用殺菌組成物 |
| JP2007500245A (ja) * | 2003-06-10 | 2007-01-11 | スミスクライン ビーチャム コーポレーション | 化合物 |
| EP2338492A1 (en) | 2009-12-24 | 2011-06-29 | Universidad del Pais Vasco | Methods and compositions for the treatment of alzheimer |
| CN103237794B (zh) | 2010-07-29 | 2016-07-06 | 日本化学医药株式会社 | P2x4受体拮抗剂 |
| EP3427729A1 (en) | 2017-07-13 | 2019-01-16 | Paris Sciences et Lettres - Quartier Latin | Probenecid for use in treating epileptic diseases, disorders or conditions |
| US10890033B1 (en) | 2017-12-10 | 2021-01-12 | Watson, Incorporated | Kelly bar with locking feature, related system and method |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3431111A (en) * | 1963-06-10 | 1969-03-04 | Eastman Kodak Co | Cyanine dyes |
| US3992378A (en) * | 1973-12-26 | 1976-11-16 | Eli Lilly And Company | Fluoralkyl quinoxadinediones |
| EP0008864A1 (en) * | 1978-08-15 | 1980-03-19 | FISONS plc | Pyridopyrazine and quinoxaline derivatives, processes for their preparation, and pharmaceutical compositions containing them |
| EP0030795A3 (en) * | 1979-12-06 | 1981-09-09 | Imperial Chemical Industries Plc | Quinoxaline derivatives, processes therefor, pharmaceutical compositions, and benzene derivatives |
| DE3165028D1 (de) * | 1980-05-09 | 1984-08-30 | Usv Pharma Corp | Triazaloquinoxalin-1,4-diones |
| US4659713A (en) * | 1984-10-01 | 1987-04-21 | International Minerals & Chemical Corp. | Quinoxalinedione compounds useful for controlling coccidiosis |
| US4812458A (en) * | 1986-09-16 | 1989-03-14 | A/S Ferrosan | 6,7-disubstituted-2,3-dihydroxyquinoxaline compounds, pharmaceutical compositions thereof, and their use as neuroleptics |
| DK146787A (da) * | 1987-03-23 | 1988-09-24 | Ferrosan | Heterocykliske forbindelser, deres fremstilling og anvendelse |
| NO179551C (no) * | 1987-11-10 | 1996-10-30 | Novo Nordisk As | Analogifremgangsmåte for fremstilling av terapeutisk virksomme kinoxalinforbindelser |
-
1988
- 1988-10-24 NO NO884729A patent/NO179551C/no not_active IP Right Cessation
- 1988-10-25 IL IL88155A patent/IL88155A0/xx not_active IP Right Cessation
- 1988-10-25 IE IE320988A patent/IE64320B1/en not_active IP Right Cessation
- 1988-11-02 PH PH37764A patent/PH25103A/en unknown
- 1988-11-03 CA CA000582104A patent/CA1321587C/en not_active Expired - Fee Related
- 1988-11-08 ES ES88118592T patent/ES2061606T3/es not_active Expired - Lifetime
- 1988-11-08 US US07/268,939 patent/US4948794A/en not_active Expired - Lifetime
- 1988-11-08 EP EP88118592A patent/EP0315959B1/en not_active Expired - Lifetime
- 1988-11-08 AT AT88118592T patent/ATE102192T1/de not_active IP Right Cessation
- 1988-11-08 DE DE3888093T patent/DE3888093T2/de not_active Expired - Fee Related
- 1988-11-09 FI FI885151A patent/FI100181B/fi not_active IP Right Cessation
- 1988-11-09 AU AU24949/88A patent/AU618766B2/en not_active Ceased
- 1988-11-09 PT PT88964A patent/PT88964B/pt active IP Right Grant
- 1988-11-09 NZ NZ226916A patent/NZ226916A/xx unknown
- 1988-11-10 KR KR1019880014744A patent/KR970011279B1/ko not_active IP Right Cessation
- 1988-11-10 JP JP63282621A patent/JP2721520B2/ja not_active Expired - Lifetime
-
1989
- 1989-12-26 US US07/456,325 patent/US5026704A/en not_active Expired - Fee Related
-
1996
- 1996-08-15 NO NO963412A patent/NO307252B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| US5026704A (en) | 1991-06-25 |
| US4948794A (en) | 1990-08-14 |
| DE3888093D1 (de) | 1994-04-07 |
| EP0315959A2 (en) | 1989-05-17 |
| NO307252B1 (no) | 2000-03-06 |
| ES2061606T3 (es) | 1994-12-16 |
| IE883209L (en) | 1989-05-10 |
| FI885151A0 (fi) | 1988-11-09 |
| FI885151A (fi) | 1989-05-11 |
| JP2721520B2 (ja) | 1998-03-04 |
| PT88964A (pt) | 1988-12-01 |
| AU2494988A (en) | 1989-05-11 |
| CA1321587C (en) | 1993-08-24 |
| IE64320B1 (en) | 1995-07-26 |
| NO179551B (no) | 1996-07-22 |
| EP0315959A3 (en) | 1989-12-27 |
| PH25103A (en) | 1991-02-19 |
| JPH01153680A (ja) | 1989-06-15 |
| AU618766B2 (en) | 1992-01-09 |
| DE3888093T2 (de) | 1994-06-09 |
| NO884729L (no) | 1989-05-11 |
| EP0315959B1 (en) | 1994-03-02 |
| NO179551C (no) | 1996-10-30 |
| NZ226916A (en) | 1991-01-29 |
| FI100181B (fi) | 1997-10-15 |
| PT88964B (pt) | 1993-02-26 |
| KR970011279B1 (ko) | 1997-07-09 |
| NO884729D0 (no) | 1988-10-24 |
| IL88155A0 (en) | 1989-06-30 |
| KR890008113A (ko) | 1989-07-08 |
| ATE102192T1 (de) | 1994-03-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM1K | Lapsed by not paying the annual fees |
Free format text: LAPSED IN APRIL 2003 |