NO961812L - Humanproteaseinhibitorer av Kunitz-type - Google Patents

Humanproteaseinhibitorer av Kunitz-type

Info

Publication number
NO961812L
NO961812L NO961812A NO961812A NO961812L NO 961812 L NO961812 L NO 961812L NO 961812 A NO961812 A NO 961812A NO 961812 A NO961812 A NO 961812A NO 961812 L NO961812 L NO 961812L
Authority
NO
Norway
Prior art keywords
dna
kunitz
protease inhibitors
type human
dna segment
Prior art date
Application number
NO961812A
Other languages
English (en)
Other versions
NO961812D0 (no
Inventor
Cindy A Sprecher
Walter Kisiel
Donald C Foster
Original Assignee
Zymogenetics Inc
Univ New Mexico
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zymogenetics Inc, Univ New Mexico filed Critical Zymogenetics Inc
Publication of NO961812D0 publication Critical patent/NO961812D0/no
Publication of NO961812L publication Critical patent/NO961812L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8114—Kunitz type inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/57—Protease inhibitors from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Cell Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

Foreliggende oppfinnelse til- veiebringer isolerte DNA-molekyler som omfatter et DNA-segment som koder for nye humaninhibitorer av Kunitz-type. Det er også tilveiebrakt DNA-konstruk- sjoner som omfatter et første DNA-seg- ment som koder for en ny humaninhibitor av Kunitz-type, hvor det første DNA- segment er operativt bundet til ytter- ligere DNA-segmenter som er påkrevet for ekspresjonen av det første DNA-seg- ment, samt vertsceller som inneholder slike DNA-konstruksjoner, og fremgangs- måter for fremstilling av proteiner fra vertscellene.
NO961812A 1993-11-05 1996-05-03 Humanproteaseinhibitorer av Kunitz-type NO961812L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/147,710 US5455338A (en) 1993-11-05 1993-11-05 DNA encoding novel human kunitz-type inhibitors and methods relating thereto
PCT/US1994/012609 WO1995012674A1 (en) 1993-11-05 1994-11-02 Human kunitz-type protease inhibitors

Publications (2)

Publication Number Publication Date
NO961812D0 NO961812D0 (no) 1996-05-03
NO961812L true NO961812L (no) 1996-07-05

Family

ID=22522614

Family Applications (1)

Application Number Title Priority Date Filing Date
NO961812A NO961812L (no) 1993-11-05 1996-05-03 Humanproteaseinhibitorer av Kunitz-type

Country Status (12)

Country Link
US (7) US5455338A (no)
EP (1) EP0726953B1 (no)
JP (1) JP3201527B2 (no)
KR (1) KR100243989B1 (no)
CN (1) CN1073159C (no)
AT (1) ATE262587T1 (no)
AU (1) AU685190B2 (no)
CA (1) CA2175797C (no)
DE (1) DE69433647T2 (no)
FI (1) FI961886A (no)
NO (1) NO961812L (no)
WO (1) WO1995012674A1 (no)

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AU2009256168B2 (en) * 2008-06-04 2014-06-05 Grifols Therapeutics Inc. Composition, method and kit for preparing plasmin
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DK2827883T3 (da) 2012-03-21 2019-07-29 Baxalta GmbH Tfpi-inhibitorer og fremgangsmåder til anvendelse
EP2970434B1 (en) * 2013-03-15 2018-12-05 The Regents of The University of California Dual reactivity potent kunitz inhibitor of fibrinolysis
CA2941693A1 (en) 2014-03-07 2015-09-11 University Health Network Methods and compositions for detection of targets involved in cancer metastasis
KR102555955B1 (ko) 2014-03-27 2023-07-18 다케다 파머수티컬 컴패니 리미티드 당뇨병성 황반 부종의 치료를 위한 조성물 및 방법
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Also Published As

Publication number Publication date
NO961812D0 (no) 1996-05-03
DE69433647T2 (de) 2004-08-05
FI961886A (fi) 1996-07-03
EP0726953B1 (en) 2004-03-24
US5455338A (en) 1995-10-03
FI961886A0 (fi) 1996-05-03
US20070092948A1 (en) 2007-04-26
KR960705850A (ko) 1996-11-08
DE69433647D1 (de) 2004-04-29
AU685190B2 (en) 1998-01-15
US20020098560A1 (en) 2002-07-25
US5728674A (en) 1998-03-17
JP3201527B2 (ja) 2001-08-20
US6656746B2 (en) 2003-12-02
US20040253686A1 (en) 2004-12-16
CA2175797A1 (en) 1995-05-11
CN1073159C (zh) 2001-10-17
CN1139955A (zh) 1997-01-08
US20050004021A1 (en) 2005-01-06
US5914315A (en) 1999-06-22
AU8131294A (en) 1995-05-23
EP0726953A1 (en) 1996-08-21
US7541449B2 (en) 2009-06-02
ATE262587T1 (de) 2004-04-15
KR100243989B1 (ko) 2000-02-01
WO1995012674A1 (en) 1995-05-11
CA2175797C (en) 2000-07-18
JPH09504696A (ja) 1997-05-13

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