BR0210835A - Moléculas de agrecanase - Google Patents
Moléculas de agrecanaseInfo
- Publication number
- BR0210835A BR0210835A BR0210835-6A BR0210835A BR0210835A BR 0210835 A BR0210835 A BR 0210835A BR 0210835 A BR0210835 A BR 0210835A BR 0210835 A BR0210835 A BR 0210835A
- Authority
- BR
- Brazil
- Prior art keywords
- agrecanase
- molecules
- enzyme
- agrecana
- proteins
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Physical Education & Sports Medicine (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
"MOLéCULAS DE AGRECANASE". A presente invenção refere-se à descrição de novas proteínas agrecanases e seq³ências de nucleotídeos que as codificam assim como os processos para a produção das mesmas. Também são descritos os métodos para o desenvolvimento de inibidores das enzimas agrecanases e de anti-corpos para as enzimas para o tratamento de condições caracterizadas pela degradação da agrecana.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US30305101P | 2001-07-05 | 2001-07-05 | |
US34913302P | 2002-01-16 | 2002-01-16 | |
PCT/US2002/021056 WO2003004607A2 (en) | 2001-07-05 | 2002-07-05 | Aggrecanase molecules |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0210835A true BR0210835A (pt) | 2004-07-13 |
Family
ID=26973233
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0210835-6A BR0210835A (pt) | 2001-07-05 | 2002-07-05 | Moléculas de agrecanase |
Country Status (9)
Country | Link |
---|---|
US (1) | US20030148306A1 (pt) |
EP (1) | EP1409658A4 (pt) |
JP (1) | JP2004533841A (pt) |
BR (1) | BR0210835A (pt) |
CA (1) | CA2451374A1 (pt) |
MX (1) | MXPA03011715A (pt) |
NZ (1) | NZ530949A (pt) |
PL (1) | PL367675A1 (pt) |
WO (1) | WO2003004607A2 (pt) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2475329A1 (en) * | 2002-02-05 | 2003-08-14 | Katy E. Georgiadis | Truncated aggrecanase molecules |
EP1525307A2 (en) * | 2002-07-29 | 2005-04-27 | Wyeth | Modified adamts4 molecules and method of use thereof |
EP1663300A1 (en) * | 2003-09-16 | 2006-06-07 | Pharmacia Corporation | Inhibitors of pace4 for the treatment of arthritis |
EP1737973A1 (en) * | 2004-04-16 | 2007-01-03 | Wyeth | Truncated adamts molecules |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4419446A (en) * | 1980-12-31 | 1983-12-06 | The United States Of America As Represented By The Department Of Health And Human Services | Recombinant DNA process utilizing a papilloma virus DNA as a vector |
US4816567A (en) * | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
WO2000058473A2 (en) * | 1999-03-31 | 2000-10-05 | Curagen Corporation | Nucleic acids including open reading frames encoding polypeptides; 'orfx' |
JP2001008687A (ja) * | 1999-06-25 | 2001-01-16 | Yamanouchi Pharmaceut Co Ltd | 新規金属プロテアーゼ及び該金属プロテアーゼ遺伝子 |
EP1234042A1 (en) * | 1999-10-25 | 2002-08-28 | Millennium Pharmaceuticals, Inc. | Protein 27875, a human adam-ts homolog |
EP1134286A3 (en) * | 2000-03-14 | 2003-05-02 | Pfizer Products Inc. | Adamts polypeptides, nucleic acids encoding them, and uses thereof |
-
2002
- 2002-07-05 JP JP2003510766A patent/JP2004533841A/ja active Pending
- 2002-07-05 MX MXPA03011715A patent/MXPA03011715A/es unknown
- 2002-07-05 NZ NZ530949A patent/NZ530949A/en unknown
- 2002-07-05 EP EP02740013A patent/EP1409658A4/en not_active Withdrawn
- 2002-07-05 US US10/188,869 patent/US20030148306A1/en not_active Abandoned
- 2002-07-05 PL PL02367675A patent/PL367675A1/xx unknown
- 2002-07-05 WO PCT/US2002/021056 patent/WO2003004607A2/en not_active Application Discontinuation
- 2002-07-05 CA CA002451374A patent/CA2451374A1/en not_active Abandoned
- 2002-07-05 BR BR0210835-6A patent/BR0210835A/pt not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP1409658A2 (en) | 2004-04-21 |
US20030148306A1 (en) | 2003-08-07 |
JP2004533841A (ja) | 2004-11-11 |
NZ530949A (en) | 2005-09-30 |
PL367675A1 (en) | 2005-03-07 |
MXPA03011715A (es) | 2004-03-19 |
WO2003004607A3 (en) | 2003-07-31 |
EP1409658A4 (en) | 2006-08-23 |
WO2003004607A2 (en) | 2003-01-16 |
CA2451374A1 (en) | 2003-01-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 5A,6A E 7A ANUIDADES. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 DA RPI 2029 DE 24/11/2009. |