BR0114719A - Moléculas de aggrecanase - Google Patents

Moléculas de aggrecanase

Info

Publication number
BR0114719A
BR0114719A BR0114719-6A BR0114719A BR0114719A BR 0114719 A BR0114719 A BR 0114719A BR 0114719 A BR0114719 A BR 0114719A BR 0114719 A BR0114719 A BR 0114719A
Authority
BR
Brazil
Prior art keywords
aggrecanase
disclosed
molecules
aggrecanase molecules
enzyme
Prior art date
Application number
BR0114719-6A
Other languages
English (en)
Inventor
Lisa Anne Racie
Natalie Constance Twine
Michael John Agostino
Neil Michael Wolfman
Elisabeth Ann Morris
Original Assignee
Inst Genetics Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst Genetics Llc filed Critical Inst Genetics Llc
Publication of BR0114719A publication Critical patent/BR0114719A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

"MOLéCULAS DE AGGRECANASE". A invenção refere-se a proteínas de aggrecanase e as seq³ências de nucleotídeo codificando-as bem como processos para produzí-las são revelados. Métodos para desenvolver inibidores das enzimas aggrecanase e anticorpos às enzimas para tratamento de condições caracterizadas pela degradação de aggrecano são também revelados.
BR0114719-6A 2000-10-20 2001-10-17 Moléculas de aggrecanase BR0114719A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24231700P 2000-10-20 2000-10-20
PCT/US2001/032596 WO2002034895A2 (en) 2000-10-20 2001-10-17 Novel aggrecanase molecules

Publications (1)

Publication Number Publication Date
BR0114719A true BR0114719A (pt) 2004-01-27

Family

ID=22914296

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0114719-6A BR0114719A (pt) 2000-10-20 2001-10-17 Moléculas de aggrecanase

Country Status (13)

Country Link
EP (1) EP1326967A2 (pt)
JP (2) JP2004512043A (pt)
AU (1) AU2002245758A1 (pt)
BR (1) BR0114719A (pt)
CA (1) CA2426463A1 (pt)
CZ (1) CZ2003996A3 (pt)
MX (1) MXPA03003425A (pt)
NO (1) NO20031649L (pt)
NZ (1) NZ525368A (pt)
PL (1) PL362008A1 (pt)
SK (1) SK4632003A3 (pt)
WO (1) WO2002034895A2 (pt)
ZA (1) ZA200303865B (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI802576B (zh) 2017-06-02 2023-05-21 德商馬克專利公司 與ａｄａｍｔｓ結合之免疫球蛋白

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6391610B1 (en) * 1999-08-06 2002-05-21 The Cleveland Clinic Foundation Nucleic acids encoding zinc metalloproteases
WO2001023561A2 (en) * 1999-09-27 2001-04-05 Curagen Corporation Novel polynucleotides encoding proteins containing thrombospondin type 1 repeats

Also Published As

Publication number Publication date
JP2004512043A (ja) 2004-04-22
EP1326967A2 (en) 2003-07-16
MXPA03003425A (es) 2004-05-04
SK4632003A3 (en) 2004-05-04
PL362008A1 (en) 2004-10-18
CZ2003996A3 (cs) 2004-04-14
NZ525368A (en) 2006-03-31
NO20031649L (no) 2003-06-11
JP2008301813A (ja) 2008-12-18
ZA200303865B (en) 2004-08-19
WO2002034895A3 (en) 2002-10-10
CA2426463A1 (en) 2002-05-02
WO2002034895A2 (en) 2002-05-02
AU2002245758A1 (en) 2002-05-06
NO20031649D0 (no) 2003-04-10

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: CONFORME ARTIGO 10O DA RESOLUCAO 124/06, CABE SER ARQUIVADO REFERENTE AO NAO RECOLHIMENTO DA 9A E 10A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2144 DE 07/02/2012.