NO960813L - Stabile transglutaminase-preparater og fremgangsmåte for fremstilling derav - Google Patents

Stabile transglutaminase-preparater og fremgangsmåte for fremstilling derav

Info

Publication number
NO960813L
NO960813L NO960813A NO960813A NO960813L NO 960813 L NO960813 L NO 960813L NO 960813 A NO960813 A NO 960813A NO 960813 A NO960813 A NO 960813A NO 960813 L NO960813 L NO 960813L
Authority
NO
Norway
Prior art keywords
preparation
stable
transglutaminase preparations
stable transglutaminase
preparations
Prior art date
Application number
NO960813A
Other languages
English (en)
Other versions
NO960813D0 (no
NO319174B1 (no
Inventor
Hubert Metzner
Hermann Karges
Original Assignee
Behringwerke Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Behringwerke Ag filed Critical Behringwerke Ag
Publication of NO960813D0 publication Critical patent/NO960813D0/no
Publication of NO960813L publication Critical patent/NO960813L/no
Publication of NO319174B1 publication Critical patent/NO319174B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1025Acyltransferases (2.3)
    • C12N9/104Aminoacyltransferases (2.3.2)
    • C12N9/1044Protein-glutamine gamma-glutamyltransferase (2.3.2.13), i.e. transglutaminase or factor XIII
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/45Transferases (2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Enzymes And Modification Thereof (AREA)
NO19960813A 1995-03-09 1996-02-28 Lyofilisert tilberedningsform av en transglutaminase samt anvendelse av denne NO319174B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19508192A DE19508192A1 (de) 1995-03-09 1995-03-09 Stabile Transglutaminasepräparate und Verfahren zu ihrer Herstellung

Publications (3)

Publication Number Publication Date
NO960813D0 NO960813D0 (no) 1996-02-28
NO960813L true NO960813L (no) 1996-09-10
NO319174B1 NO319174B1 (no) 2005-06-27

Family

ID=7756017

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19960813A NO319174B1 (no) 1995-03-09 1996-02-28 Lyofilisert tilberedningsform av en transglutaminase samt anvendelse av denne

Country Status (13)

Country Link
US (1) US6204036B1 (no)
EP (1) EP0733702B1 (no)
JP (1) JP3530300B2 (no)
KR (1) KR100457485B1 (no)
CN (1) CN1149283C (no)
AT (1) ATE239783T1 (no)
AU (1) AU4791596A (no)
CA (1) CA2171266C (no)
DE (2) DE19508192A1 (no)
ES (1) ES2194935T3 (no)
IL (1) IL117405A (no)
NO (1) NO319174B1 (no)
NZ (1) NZ286046A (no)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6030821A (en) * 1994-10-11 2000-02-29 Ajinomoto Co., Inc. Stabilized transglutaminase and enzyme preparation containing the same
JPH08333277A (ja) * 1995-06-05 1996-12-17 Hoechst Japan Ltd ヒト血液凝固第xiii因子の安定化された水性液製剤
EP0852951A1 (de) * 1996-11-19 1998-07-15 Roche Diagnostics GmbH Stabile lyophilisierte pharmazeutische Zubereitungen von mono- oder polyklonalen Antikörpern
CA2280130C (en) * 1997-02-05 2007-12-18 Kirin Beer Kabushiki Kaisha Lyophilized compositions containing sphingoglycolipid and process for preparing them
US6417167B1 (en) 1997-02-05 2002-07-09 Kirin Beer Kabushiki Kaisha Lyophilized compositions containing shingoglycolipid and process for preparing them
JP4524076B2 (ja) * 2003-04-02 2010-08-11 天野エンザイム株式会社 安定化トランスグルタミナーゼ
DE10333317A1 (de) * 2003-07-22 2005-02-17 Biotecon Therapeutics Gmbh Formulierung für Proteinarzneimittel ohne Zusatz von humanem Serumalbumin (HSA)
EP1609800B1 (de) * 2004-06-25 2007-11-14 Kühni Ag Verfahren zur Extraktion von biologischem Material
ATE428416T1 (de) * 2005-06-21 2009-05-15 Merck Patent Gmbh Feste pharmazeutische zubereitung enthaltend (r)- (-)-2-ä5-(4-fluorophenyl)-3- pyridylmethylaminomethylü-chroman
WO2007033427A1 (en) * 2005-09-23 2007-03-29 Metabolic Pharmaceuticals Limited Stabilisation of peptides with basic amino acids
DE102006033167A1 (de) * 2006-07-10 2008-01-24 Gelita Ag Verwendung von Gelatine und einem Vernetzungsmittel zur Herstellung eines vernetzenden medizinischen Klebers
GB0710529D0 (en) * 2007-06-01 2007-07-11 Circassia Ltd Vaccine
WO2008155529A1 (en) * 2007-06-16 2008-12-24 Enigma Diagnostics Limited Compositions
SI2190473T1 (sl) * 2007-08-15 2013-05-31 Circassia Limited Peptid z zmanjšano tvorbo dimerov
KR101710471B1 (ko) * 2008-04-21 2017-02-27 노보 노르디스크 헬스 케어 악티엔게젤샤프트 건조한 트랜스글루타미나제 조성물
GB0821806D0 (en) 2008-11-28 2009-01-07 Circassia Ltd Compositions with reduced dimer formation
AU2015227499B2 (en) * 2008-11-28 2017-06-22 Circassia Limited Compositions with reduced dimer formation
US20100316764A1 (en) * 2009-06-10 2010-12-16 Engrain, LLC Flour supplement compositions and methods for preparing wheat flour
CN101995459A (zh) * 2009-08-26 2011-03-30 刘萍 包被板封闭液
CA2806111A1 (en) * 2010-07-22 2012-01-26 Hansa Medical Ab An ancestral serine protease coagulation cascade exerts a novel function in early immune defense
CN102533689A (zh) * 2011-12-30 2012-07-04 华东师范大学 一种谷氨酰胺转胺酶真空干燥的制备方法
CN104274827B (zh) * 2013-07-01 2020-07-14 上海贺普药业股份有限公司 贺普拉肽的制剂
CN104198422B (zh) * 2014-08-18 2017-04-19 苏州康铭诚业医用科技有限公司 一种用于α‑羟丁酸脱氢酶测定试剂盒的复合稳定剂
CN104388531B (zh) * 2014-10-20 2017-01-18 苏州康铭诚业医用科技有限公司 一种用于乳酸脱氢酶试剂盒的复合稳定剂
CN105018457A (zh) * 2015-07-20 2015-11-04 宁波美成生物科技有限公司 虫荧光素酶稳定剂
WO2017104759A1 (ja) * 2015-12-16 2017-06-22 株式会社 資生堂 タブレット型凍結乾燥化粧料
CN105543204A (zh) * 2015-12-30 2016-05-04 海口奇力制药股份有限公司 一种组合物及其应用、含有该组合物的稳定剂
CN107177567B (zh) * 2016-02-16 2018-07-03 上海青瑞食品科技有限公司 一种液体酶制剂及制备方法
WO2018050870A1 (en) 2016-09-16 2018-03-22 Leukocare Ag A novel method for stabilization of a biopharmaceutical drug product during processing

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2063070C3 (de) 1970-12-22 1975-07-24 Behringwerke Ag, 3550 Marburg Verfahren zur Herstellung eines Arzneimittels mit fibrinstabilisierender Wirkung
JPS5359018A (en) 1976-11-10 1978-05-27 Green Cross Corp:The Concentrated xiii-th blood coagulating factor derived from human placentaand its preparation
DE2916711A1 (de) * 1979-04-25 1980-11-06 Behringwerke Ag Blutgerinnungsfaktoren und verfahren zu ihrer herstellung
JPS56135418A (en) * 1980-03-27 1981-10-22 Green Cross Corp:The Heat treatment of aqueous solution containing 8 factor of coagulation of blood derived from human
JPH03240738A (ja) * 1990-02-20 1991-10-28 Hoechst Japan Ltd 糖尿病性壊疽治療剤
FR2664165B1 (fr) * 1990-07-03 1992-10-16 Lille Transfusion Sanguine Composition pour stabiliser le plasma sanguin en cours de pasteurisation.
ES2110515T3 (es) 1991-08-07 1998-02-16 Zymogenetics Inc Purificacion del factor xiii.
WO1993015234A1 (en) * 1992-01-22 1993-08-05 Novo Nordisk A/S Activated factor xiii
JP3353383B2 (ja) * 1992-06-02 2002-12-03 味の素株式会社 酵素製剤及び結着成形食品の製造法
DE69326101T2 (de) * 1992-06-02 2000-04-20 Ajinomoto Co., Inc. Verfahren zur Herstellung eines geformten gebundenen Nahrungsmittels
AT402788B (de) * 1993-08-03 1997-08-25 Immuno Ag Virussichere blutgerinnungsfaktor xiii-präparation

Also Published As

Publication number Publication date
NZ286046A (en) 1997-09-22
NO960813D0 (no) 1996-02-28
AU4791596A (en) 1996-09-19
KR100457485B1 (ko) 2005-02-02
IL117405A (en) 2002-05-23
EP0733702B1 (de) 2003-05-07
JPH08245418A (ja) 1996-09-24
IL117405A0 (en) 1996-07-23
EP0733702A1 (de) 1996-09-25
US6204036B1 (en) 2001-03-20
KR960034408A (ko) 1996-10-22
NO319174B1 (no) 2005-06-27
CN1137564A (zh) 1996-12-11
ATE239783T1 (de) 2003-05-15
CA2171266C (en) 2010-05-18
JP3530300B2 (ja) 2004-05-24
CN1149283C (zh) 2004-05-12
DE59610414D1 (de) 2003-06-12
CA2171266A1 (en) 1996-09-10
ES2194935T3 (es) 2003-12-01
DE19508192A1 (de) 1996-09-12

Similar Documents

Publication Publication Date Title
NO960813D0 (no) Stabile transglutaminase-preparater og fremgangsmåte for fremstilling derav
ATE262042T1 (de) Pflanzliche mittelkettige thioesterasen
DK0410207T3 (da) Stabilisering af højrensede proteiner.
DE69212254D1 (de) Haarpflegemittel
DE69416764D1 (de) Verfahren zur Stabilisierung eines Kontaktlinsenpräparats
BR9302724A (pt) Processo para preparar polissuccinimidas
KR960705580A (ko) 단백질 C 또는 활성화 단백질 C를 안정화시키는 방법 및 안정화된 조성물(Method of stabilizing protein C or activated protein C and stabilized composition)
ES2089661T3 (es) Soluciones para inyeccion de mesna.
BR9002240A (pt) Processo para a preparacao de uma composicao conservada apropriada para aplicacao topica a pele e composicao
ES2156190T3 (es) Procedimiento para la prevencion de la degradacion de la proteina c.
BR9004692A (pt) Composicao trombolitica e infusao para injecao
BR9004693A (pt) Solucao aquosa,processo para aumentar a concentracao de proteina de uma proteina em uma solucao aquosa,e composicao farmaceutica
Matsumoto et al. Physical properties of glutamate decarboxylase from squash
ES2178639T3 (es) Solucion estable de aminoacidos altamente concentrada.
DK0686694T3 (da) Anvendelse af azoler som virucide midler i opløsninger af biologisk aktive proteiner
DE59802825D1 (de) Verfahren zur Herstellung von 4-Nitro-2-sulfo-benzoesäure
ES8702436A1 (es) Procedimiento para la sintesis de dipeptidos de n elevado a alfa-acil arginina de cadena grasa e hidrolizados de proteina como tensioactivos ionicos de accion antimicrobiana
RU95104309A (ru) Коллагеназа
KR880007569A (ko) 히아론산의 정제방법

Legal Events

Date Code Title Description
MK1K Patent expired