ES2110515T3 - Purificacion del factor xiii. - Google Patents

Purificacion del factor xiii.

Info

Publication number
ES2110515T3
ES2110515T3 ES92918137T ES92918137T ES2110515T3 ES 2110515 T3 ES2110515 T3 ES 2110515T3 ES 92918137 T ES92918137 T ES 92918137T ES 92918137 T ES92918137 T ES 92918137T ES 2110515 T3 ES2110515 T3 ES 2110515T3
Authority
ES
Spain
Prior art keywords
factor xiii
purification
methods
compositions
purified
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92918137T
Other languages
English (en)
Inventor
Mads Laustsen
Jin-Jyi Chang
Paul D Bishop
Gerald W Lasser
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zymogenetics Inc
Original Assignee
Zymogenetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zymogenetics Inc filed Critical Zymogenetics Inc
Application granted granted Critical
Publication of ES2110515T3 publication Critical patent/ES2110515T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/104—Aminoacyltransferases (2.3.2)
    • C12N9/1044—Protein-glutamine gamma-glutamyltransferase (2.3.2.13), i.e. transglutaminase or factor XIII

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Fishing Rods (AREA)
  • Detergent Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • External Artificial Organs (AREA)

Abstract

SE PRESENTA UN FACTOR XIII ALTAMENTE PURIFICADO Y METODOS PARA PURIFICAR EL FACTOR XIII. EL FACTOR XIII SE PURIFICA A PARTIR DE UN FLUIDO BIOLOGICO, TAL COMO LISATO CELULAR. LOS METODOS SUMINISTRAN COMPOSICIONES DE FACTOR XIII QUE SON MAS DE UN 99% PURAS CON RESPECTO A LAS PROTEINAS CONTAMINANTES. LOS METODOS SUMINISTRAN ADEMAS COMPOSICIONES DEL FACTOR XIII EN LAS QUE UN 1% O MENOS DEL FACTOR XIII ES FACTOR XIII ACTIVADO.
ES92918137T 1991-08-07 1992-08-07 Purificacion del factor xiii. Expired - Lifetime ES2110515T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US74126391A 1991-08-07 1991-08-07

Publications (1)

Publication Number Publication Date
ES2110515T3 true ES2110515T3 (es) 1998-02-16

Family

ID=24980018

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92918137T Expired - Lifetime ES2110515T3 (es) 1991-08-07 1992-08-07 Purificacion del factor xiii.

Country Status (10)

Country Link
EP (1) EP0603215B1 (es)
JP (1) JP3415148B2 (es)
AT (1) ATE159756T1 (es)
AU (1) AU2478292A (es)
CA (1) CA2115136C (es)
DE (1) DE69222947T2 (es)
DK (1) DK0603215T3 (es)
ES (1) ES2110515T3 (es)
GR (1) GR3025944T3 (es)
WO (1) WO1993003147A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19508192A1 (de) 1995-03-09 1996-09-12 Behringwerke Ag Stabile Transglutaminasepräparate und Verfahren zu ihrer Herstellung
US20080176789A1 (en) 2004-08-27 2008-07-24 Novc Nordisk Healthcare A/G Purification of Factor Xlll Polypeptides From Biological Materials
CA2587139C (en) 2004-11-23 2014-05-27 Zymogenetics, Inc. Purification of recombinant human factor xiii
FR2887883B1 (fr) 2005-06-29 2007-08-31 Lab Francais Du Fractionnement Procede de separation des proteines fibrinogene, facteur xiii et colle biologique d'une fraction plasmatique solubilisee et de preparation de concentres lyophilises desdites proteines
SG191186A1 (en) 2010-12-15 2013-07-31 Baxter Int Eluate collection using conductivity gradient

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5204447A (en) * 1988-11-14 1993-04-20 Zymogenetics, Inc. Purification of factor xiii

Also Published As

Publication number Publication date
JP3415148B2 (ja) 2003-06-09
EP0603215B1 (en) 1997-10-29
WO1993003147A1 (en) 1993-02-18
GR3025944T3 (en) 1998-04-30
JPH07506479A (ja) 1995-07-20
EP0603215A1 (en) 1994-06-29
AU2478292A (en) 1993-03-02
CA2115136C (en) 1997-01-07
DE69222947T2 (de) 1998-05-07
CA2115136A1 (en) 1993-02-18
DK0603215T3 (da) 1997-12-01
DE69222947D1 (de) 1997-12-04
ATE159756T1 (de) 1997-11-15

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