NO955007L - Tiolforbindelser - Google Patents

Tiolforbindelser

Info

Publication number
NO955007L
NO955007L NO955007A NO955007A NO955007L NO 955007 L NO955007 L NO 955007L NO 955007 A NO955007 A NO 955007A NO 955007 A NO955007 A NO 955007A NO 955007 L NO955007 L NO 955007L
Authority
NO
Norway
Prior art keywords
thiol compounds
compounds
thiazolin
mercapto
intermediates
Prior art date
Application number
NO955007A
Other languages
English (en)
Other versions
NO955007D0 (no
Inventor
Kazuhiko Hayashi
Chisato Sato
Satoshi Tamai
Original Assignee
Lederle Japan Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lederle Japan Ltd filed Critical Lederle Japan Ltd
Publication of NO955007D0 publication Critical patent/NO955007D0/no
Publication of NO955007L publication Critical patent/NO955007L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Chemical Vapour Deposition (AREA)
  • Saccharide Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Processing Of Solid Wastes (AREA)

Abstract

Foreliggende oppfinnelse vedrører 3-merkapto-l-(l,3- tiazolin-2-yl)azetidin med den følgende formel og dets syreaddisjonssalter * og fremgangsmåter ved deres fremstilling. Disse forbindelser er nyttige som mellomprodukter ved fremstilling av karbapenemforbindelser med en sterk antibakteriell virkning, og de kan fremstilles med letthet og i høyt utbytte.
NO955007A 1994-12-12 1995-12-11 Tiolforbindelser NO955007L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP33142394 1994-12-12
JP25728195 1995-09-11

Publications (2)

Publication Number Publication Date
NO955007D0 NO955007D0 (no) 1995-12-11
NO955007L true NO955007L (no) 1996-06-13

Family

ID=26543132

Family Applications (1)

Application Number Title Priority Date Filing Date
NO955007A NO955007L (no) 1994-12-12 1995-12-11 Tiolforbindelser

Country Status (15)

Country Link
US (1) US5659043A (no)
EP (1) EP0717042B1 (no)
KR (1) KR100337053B1 (no)
AT (1) ATE201410T1 (no)
AU (1) AU703119B2 (no)
CA (1) CA2164918C (no)
DE (1) DE69521012T2 (no)
DK (1) DK0717042T3 (no)
ES (1) ES2156917T3 (no)
FI (1) FI120402B (no)
GR (1) GR3035925T3 (no)
HU (4) HU223476B1 (no)
IL (1) IL116331A (no)
NO (1) NO955007L (no)
PT (1) PT717042E (no)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100451670B1 (ko) * 2001-09-14 2004-10-08 한국화학연구원 내성균에 대해 항생작용을 갖는 카바페넴 유도체 및 이의제조방법
KR100621782B1 (ko) * 2004-06-14 2006-09-19 한국과학기술연구원 1-베타메틸카바페넴 유도체 및 이의 제조방법
CN102532139A (zh) * 2010-12-07 2012-07-04 重庆医药工业研究院有限责任公司 一种替比培南的制备方法
CN102731503B (zh) * 2011-04-13 2016-02-03 石药集团中奇制药技术（石家庄）有限公司 一种泰比培南的制备方法
CN102731502B (zh) * 2011-04-13 2016-08-03 石药集团中奇制药技术（石家庄）有限公司 一种碳青霉烯抗生素的制备方法
CN102250080B (zh) * 2011-04-26 2015-06-03 广州白云山制药股份有限公司广州白云山制药总厂 一种1-(4,5-二氢-2-噻唑啉基)-3-巯基吖丁叮盐酸盐的制备方法
CN102757430B (zh) * 2011-04-29 2016-04-13 上海医药工业研究院 一种替比培南的制备方法
CN104292222B (zh) * 2013-07-17 2017-05-10 常州锐博生物科技有限公司 一种替比培南匹伏酯侧链的新的合成方法
TWI759267B (zh) 2015-07-02 2022-04-01 美商地平線罕見醫學製藥有限責任公司 Ａｄｏ抗性半胱胺類似物及其用途
CN112321582B (zh) * 2020-11-03 2021-12-03 江西富祥药业股份有限公司 一种泰比培南侧链的合成及中间体的精制方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU682510B2 (en) * 1993-07-01 1997-10-09 Pfizer Japan Inc. 2-(1-(1,3-thiazolin-2-yl)azetidin-3-yl)thio-carbapenem derivatives

Also Published As

Publication number Publication date
US5659043A (en) 1997-08-19
HU0203890D0 (en) 2003-01-28
HU223472B1 (hu) 2004-07-28
DE69521012D1 (de) 2001-06-28
ATE201410T1 (de) 2001-06-15
NO955007D0 (no) 1995-12-11
PT717042E (pt) 2001-08-30
ES2156917T3 (es) 2001-08-01
AU4035995A (en) 1996-06-20
IL116331A0 (en) 1996-03-31
DK0717042T3 (da) 2001-08-06
GR3035925T3 (en) 2001-08-31
HU223476B1 (hu) 2004-07-28
KR100337053B1 (ko) 2002-11-07
IL116331A (en) 2000-02-17
HU223477B1 (hu) 2004-07-28
CA2164918A1 (en) 1996-06-13
CA2164918C (en) 2007-09-25
HU223536B1 (hu) 2004-08-30
HU0203892D0 (en) 2003-01-28
DE69521012T2 (de) 2001-09-06
EP0717042A1 (en) 1996-06-19
FI955954A0 (fi) 1995-12-12
FI955954A (fi) 1996-06-13
HU9503548D0 (en) 1996-02-28
KR960022512A (ko) 1996-07-18
AU703119B2 (en) 1999-03-18
HUT75098A (en) 1997-04-28
EP0717042B1 (en) 2001-05-23
FI120402B (fi) 2009-10-15
HU0203891D0 (en) 2003-01-28

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