NO941269L - Kjemiske forbindelser - Google Patents

Kjemiske forbindelser

Info

Publication number
NO941269L
NO941269L NO941269A NO941269A NO941269L NO 941269 L NO941269 L NO 941269L NO 941269 A NO941269 A NO 941269A NO 941269 A NO941269 A NO 941269A NO 941269 L NO941269 L NO 941269L
Authority
NO
Norway
Prior art keywords
acid
nucleosides
fatty acid
ara
esters
Prior art date
Application number
NO941269A
Other languages
English (en)
Other versions
NO941269D0 (no
NO300014B1 (no
Inventor
Are Dalen
Bernt Boerretzen
Finn Myhren
Kjell Torgeir Stokke
Original Assignee
Norsk Hydro As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Norsk Hydro As filed Critical Norsk Hydro As
Priority to NO941269A priority Critical patent/NO300014B1/no
Publication of NO941269D0 publication Critical patent/NO941269D0/no
Publication of NO941269L publication Critical patent/NO941269L/no
Publication of NO300014B1 publication Critical patent/NO300014B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Mechanical Coupling Of Light Guides (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • External Artificial Organs (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NO941269A 1991-10-07 1994-04-07 Kjemiske forbindelser NO300014B1 (no)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NO941269A NO300014B1 (no) 1991-10-07 1994-04-07 Kjemiske forbindelser

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9121257A GB2260319B (en) 1991-10-07 1991-10-07 Acyl derivatives of nucleosides and nucleoside analogues having anti-viral activity
PCT/NO1992/000162 WO1993007163A1 (en) 1991-10-07 1992-09-30 Chemical compounds
NO941269A NO300014B1 (no) 1991-10-07 1994-04-07 Kjemiske forbindelser

Publications (3)

Publication Number Publication Date
NO941269D0 NO941269D0 (no) 1994-04-07
NO941269L true NO941269L (no) 1994-04-07
NO300014B1 NO300014B1 (no) 1997-03-17

Family

ID=10702531

Family Applications (1)

Application Number Title Priority Date Filing Date
NO941269A NO300014B1 (no) 1991-10-07 1994-04-07 Kjemiske forbindelser

Country Status (27)

Country Link
US (1) US6548486B1 (no)
EP (1) EP0642525B1 (no)
JP (1) JP2873313B2 (no)
KR (1) KR100272732B1 (no)
AT (1) ATE152454T1 (no)
CA (1) CA2120725C (no)
CH (1) CH0642525H1 (no)
CZ (1) CZ288153B6 (no)
DE (1) DE69219482T2 (no)
DK (1) DK0642525T3 (no)
FI (2) FI105035B (no)
GB (1) GB2260319B (no)
GR (1) GR3024149T3 (no)
HK (1) HK1007430A1 (no)
HU (1) HU219400B (no)
IL (1) IL103351A (no)
MX (1) MX9205715A (no)
NO (1) NO300014B1 (no)
NZ (1) NZ244535A (no)
PL (1) PL170846B1 (no)
RU (1) RU2126417C1 (no)
SG (1) SG47759A1 (no)
SK (1) SK281903B6 (no)
TW (1) TW347333B (no)
UA (1) UA41296C2 (no)
WO (1) WO1993007163A1 (no)
ZA (1) ZA927432B (no)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9307043D0 (en) * 1993-04-05 1993-05-26 Norsk Hydro As Chemical compounds
US5869493A (en) * 1996-02-16 1999-02-09 Medivir Ab Acyclic nucleoside derivatives
US6703394B2 (en) 1996-02-16 2004-03-09 Medivir Ab Acyclic nucleoside derivatives
GB2321455A (en) * 1997-01-24 1998-07-29 Norsk Hydro As Lipophilic derivatives of biologically active compounds
GB0201179D0 (en) * 2002-01-18 2002-03-06 Angeletti P Ist Richerche Bio Therapeutic agents
TWI332507B (en) 2002-11-19 2010-11-01 Hoffmann La Roche Antiviral nucleoside derivatives
WO2006101911A1 (en) 2005-03-16 2006-09-28 Case Western Reserve University Selective inhibitors of translesion dna replication
WO2008147454A1 (en) * 2006-11-16 2008-12-04 Case Western Reserve University Selective inhibitors of translesion dna replication
NO324263B1 (no) * 2005-12-08 2007-09-17 Clavis Pharma Asa Kjemiske forbindelser, anvendelse derav ved behandling av kreft, samt farmasoytiske preparater som omfatter slike forbindelser
US8497292B2 (en) * 2005-12-28 2013-07-30 Translational Therapeutics, Inc. Translational dysfunction based therapeutics
US20090111774A1 (en) * 2007-06-01 2009-04-30 Luitpold Pharmaceuticals, Inc. Pmea lipid conjugates
MX2010000424A (es) 2007-07-09 2010-08-10 Easter Virginia Medical School Derivados de nucleosidos sustituidos con propiedades antivirales y antimicrobianas.
EP2205073A4 (en) * 2007-09-26 2013-03-06 Sinai School Medicine AZACYTIDINE ANALOGS AND USES THEREOF
EP2825546B1 (en) 2011-09-01 2017-07-12 Case Western Reserve University Non-natural nucleosides as theranostic agents
US9493500B2 (en) 2012-07-19 2016-11-15 Richard Daifuku Fluorinated pyrimidine analogs and methods of use thereof
US9821173B2 (en) 2013-02-08 2017-11-21 Case Western Reserve University Anti-cancer agents and methods of use
RU2621145C2 (ru) * 2015-11-03 2017-05-31 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Воронежский государственный университет" (ФГБОУ ВПО "ВГУ") Способ получения липосом
EP3762396A1 (en) * 2018-03-07 2021-01-13 GlaxoSmithKline Intellectual Property (No.2) Limited Compounds useful in hiv therapy

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1325797A (en) 1970-09-24 1973-08-08 Upjohn Co Medicines comprising cytidine derivatives
US3920630A (en) * 1970-09-24 1975-11-18 Upjohn Co 2,2{40 -Anhydro-ara-cytidine compounds and process of preparation
US4211773A (en) * 1978-10-02 1980-07-08 Sloan Kettering Institute For Cancer Research 5-Substituted 1-(2'-Deoxy-2'-substituted-β-D-arabinofuranosyl)pyrimidine nucleosides
DE3100478A1 (de) * 1981-01-09 1982-08-12 Dr. Thilo & Co GmbH, 8021 Sauerlach 5'ester von pyrimidinnucleosiden mit antiviraler wirksamkeit, verfahren zur herstellung und daraus hergestellte arzneimittel
US4355032B2 (en) 1981-05-21 1990-10-30 9-(1,3-dihydroxy-2-propoxymethyl)guanine as antiviral agent
US4816447A (en) 1981-08-26 1989-03-28 Merck & Co., Inc. Anti-viral guanine compounds
NZ201662A (en) 1981-08-26 1986-07-11 Merck & Co Inc 9-(1,3-(and 2,3)-dihydroxy-1-(and 2)-propoxy-methyl)guanine derivatives and methods for their preparation
US5250535A (en) * 1982-02-01 1993-10-05 Syntex Inc. Substituted 9-(1 or 3-monoacyloxy or 1,3-diacyloxy-2-propoxymethyl) purines as antiviral agent
US4556659A (en) * 1982-08-09 1985-12-03 Syntex (U.S.A.) Inc. Substituted 9-(1-0- or 3-0-monosubstituted or 1,3-Di-0-substituted propoxymethyl)-purines as antiviral agents
JPH0655755B2 (ja) 1985-01-23 1994-07-27 富山化学工業株式会社 新規な５−フルオロ−２′−デオキシウリジン−３′−ホスフエ−ト誘導体およびその塩
US4684631A (en) 1984-10-09 1987-08-04 Toyama Chemical Co., Ltd. Novel 5-fluoro-2-deoxyuridine derivatives and salts thereof, process for producing the same, and antitumor agents containing the same
US5223263A (en) * 1988-07-07 1993-06-29 Vical, Inc. Liponucleotide-containing liposomes
JPS6483092A (en) 1987-09-24 1989-03-28 Arakawa Chotaro & Co Novel n6,n6-dimethyladenosine derivative having carcinostatic activity, its production and carcinostatic agent containing said derivative as active component
EP0355131B1 (en) * 1987-10-28 1996-09-04 Pro-Neuron, Inc. Acyl deoxyribonucleoside derivatives and uses thereof
JPH0278696A (ja) 1988-09-13 1990-03-19 Shoichiro Ozaki ５−フルオロウラシル誘導体
US5216142A (en) * 1989-04-17 1993-06-01 Efamol Holdings Plc Anti-virals
RU2085557C1 (ru) * 1991-09-30 1997-07-27 Санкио Компани Лимитед Производные нуклеозидов пиримидина или их фармацевтически приемлемые соли и способ их получения

Also Published As

Publication number Publication date
HU9400988D0 (en) 1994-07-28
FI941574A0 (fi) 1994-04-06
FI990270A (fi) 1999-02-10
ZA927432B (en) 1993-06-09
SK281903B6 (sk) 2001-09-11
DE69219482D1 (de) 1997-06-05
FI105035B (fi) 2000-05-31
US6548486B1 (en) 2003-04-15
WO1993007163A1 (en) 1993-04-15
EP0642525B1 (en) 1997-05-02
RU2126417C1 (ru) 1999-02-20
HU219400B (hu) 2001-04-28
JPH06511249A (ja) 1994-12-15
GB9121257D0 (en) 1991-11-20
CZ80594A3 (en) 1994-12-15
ATE152454T1 (de) 1997-05-15
GB2260319B (en) 1995-12-06
KR100272732B1 (ko) 2000-11-15
NO941269D0 (no) 1994-04-07
FI990270A0 (fi) 1999-02-10
HK1007430A1 (en) 1999-04-09
MX9205715A (es) 1993-05-01
CA2120725C (en) 2000-04-11
TW347333B (en) 1998-12-11
EP0642525A1 (en) 1995-03-15
IL103351A0 (en) 1993-03-15
UA41296C2 (uk) 2001-09-17
GB2260319A (en) 1993-04-14
FI941574A (fi) 1994-04-06
PL170846B1 (en) 1997-01-31
HUT68008A (en) 1995-05-29
DE69219482T2 (de) 1997-10-23
NZ244535A (en) 1995-08-28
AU672369B2 (en) 1996-10-03
CH0642525H1 (en) 1999-06-30
NO300014B1 (no) 1997-03-17
SK39794A3 (en) 1994-10-05
IL103351A (en) 2000-02-17
GR3024149T3 (en) 1997-10-31
JP2873313B2 (ja) 1999-03-24
CA2120725A1 (en) 1993-04-15
AU2867392A (en) 1993-05-03
DK0642525T3 (da) 1997-11-03
SG47759A1 (en) 1998-04-17
CZ288153B6 (en) 2001-05-16

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