FI990270A - Uuden monoesteriyhdisteet - Google Patents
Uuden monoesteriyhdisteet Download PDFInfo
- Publication number
- FI990270A FI990270A FI990270A FI990270A FI990270A FI 990270 A FI990270 A FI 990270A FI 990270 A FI990270 A FI 990270A FI 990270 A FI990270 A FI 990270A FI 990270 A FI990270 A FI 990270A
- Authority
- FI
- Finland
- Prior art keywords
- acid
- nucleosides
- fatty acid
- new
- ara
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Virology (AREA)
- Public Health (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Mechanical Coupling Of Light Guides (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- External Artificial Organs (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9121257A GB2260319B (en) | 1991-10-07 | 1991-10-07 | Acyl derivatives of nucleosides and nucleoside analogues having anti-viral activity |
| PCT/NO1992/000162 WO1993007163A1 (en) | 1991-10-07 | 1992-09-30 | Chemical compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FI990270A true FI990270A (fi) | 1999-02-10 |
| FI990270A0 FI990270A0 (fi) | 1999-02-10 |
Family
ID=10702531
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI941574A FI105035B (fi) | 1991-10-07 | 1994-04-06 | Menetelmä uuden, terapeuttisesti aktiivisen monoesteriyhdisteen valmistamiseksi |
| FI990270A FI990270A0 (fi) | 1991-10-07 | 1999-02-10 | Uuden monoesteriyhdisteet |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI941574A FI105035B (fi) | 1991-10-07 | 1994-04-06 | Menetelmä uuden, terapeuttisesti aktiivisen monoesteriyhdisteen valmistamiseksi |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US6548486B1 (fi) |
| EP (1) | EP0642525B1 (fi) |
| JP (1) | JP2873313B2 (fi) |
| KR (1) | KR100272732B1 (fi) |
| AT (1) | ATE152454T1 (fi) |
| CA (1) | CA2120725C (fi) |
| CH (1) | CH0642525H1 (fi) |
| CZ (1) | CZ288153B6 (fi) |
| DE (1) | DE69219482T2 (fi) |
| DK (1) | DK0642525T3 (fi) |
| FI (2) | FI105035B (fi) |
| GB (1) | GB2260319B (fi) |
| GR (1) | GR3024149T3 (fi) |
| HK (1) | HK1007430A1 (fi) |
| HU (1) | HU219400B (fi) |
| IL (1) | IL103351A (fi) |
| MX (1) | MX9205715A (fi) |
| NO (1) | NO300014B1 (fi) |
| NZ (1) | NZ244535A (fi) |
| PL (1) | PL170846B1 (fi) |
| RU (1) | RU2126417C1 (fi) |
| SG (1) | SG47759A1 (fi) |
| SK (1) | SK281903B6 (fi) |
| TW (1) | TW347333B (fi) |
| UA (1) | UA41296C2 (fi) |
| WO (1) | WO1993007163A1 (fi) |
| ZA (1) | ZA927432B (fi) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9307043D0 (en) * | 1993-04-05 | 1993-05-26 | Norsk Hydro As | Chemical compounds |
| US5869493A (en) * | 1996-02-16 | 1999-02-09 | Medivir Ab | Acyclic nucleoside derivatives |
| US6703394B2 (en) | 1996-02-16 | 2004-03-09 | Medivir Ab | Acyclic nucleoside derivatives |
| GB2321455A (en) * | 1997-01-24 | 1998-07-29 | Norsk Hydro As | Lipophilic derivatives of biologically active compounds |
| GB0201179D0 (en) * | 2002-01-18 | 2002-03-06 | Angeletti P Ist Richerche Bio | Therapeutic agents |
| TWI332507B (en) | 2002-11-19 | 2010-11-01 | Hoffmann La Roche | Antiviral nucleoside derivatives |
| WO2006101911A1 (en) | 2005-03-16 | 2006-09-28 | Case Western Reserve University | Selective inhibitors of translesion dna replication |
| WO2008147454A1 (en) * | 2006-11-16 | 2008-12-04 | Case Western Reserve University | Selective inhibitors of translesion dna replication |
| NO324263B1 (no) * | 2005-12-08 | 2007-09-17 | Clavis Pharma Asa | Kjemiske forbindelser, anvendelse derav ved behandling av kreft, samt farmasoytiske preparater som omfatter slike forbindelser |
| US8497292B2 (en) * | 2005-12-28 | 2013-07-30 | Translational Therapeutics, Inc. | Translational dysfunction based therapeutics |
| US20090111774A1 (en) * | 2007-06-01 | 2009-04-30 | Luitpold Pharmaceuticals, Inc. | Pmea lipid conjugates |
| MX2010000424A (es) | 2007-07-09 | 2010-08-10 | Easter Virginia Medical School | Derivados de nucleosidos sustituidos con propiedades antivirales y antimicrobianas. |
| EP2205073A4 (en) * | 2007-09-26 | 2013-03-06 | Sinai School Medicine | AZACYTIDINE ANALOGS AND USES THEREOF |
| EP2825546B1 (en) | 2011-09-01 | 2017-07-12 | Case Western Reserve University | Non-natural nucleosides as theranostic agents |
| US9493500B2 (en) | 2012-07-19 | 2016-11-15 | Richard Daifuku | Fluorinated pyrimidine analogs and methods of use thereof |
| US9821173B2 (en) | 2013-02-08 | 2017-11-21 | Case Western Reserve University | Anti-cancer agents and methods of use |
| RU2621145C2 (ru) * | 2015-11-03 | 2017-05-31 | Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Воронежский государственный университет" (ФГБОУ ВПО "ВГУ") | Способ получения липосом |
| EP3762396A1 (en) * | 2018-03-07 | 2021-01-13 | GlaxoSmithKline Intellectual Property (No.2) Limited | Compounds useful in hiv therapy |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1325797A (en) | 1970-09-24 | 1973-08-08 | Upjohn Co | Medicines comprising cytidine derivatives |
| US3920630A (en) * | 1970-09-24 | 1975-11-18 | Upjohn Co | 2,2{40 -Anhydro-ara-cytidine compounds and process of preparation |
| US4211773A (en) * | 1978-10-02 | 1980-07-08 | Sloan Kettering Institute For Cancer Research | 5-Substituted 1-(2'-Deoxy-2'-substituted-β-D-arabinofuranosyl)pyrimidine nucleosides |
| DE3100478A1 (de) * | 1981-01-09 | 1982-08-12 | Dr. Thilo & Co GmbH, 8021 Sauerlach | 5'ester von pyrimidinnucleosiden mit antiviraler wirksamkeit, verfahren zur herstellung und daraus hergestellte arzneimittel |
| US4355032B2 (en) | 1981-05-21 | 1990-10-30 | 9-(1,3-dihydroxy-2-propoxymethyl)guanine as antiviral agent | |
| US4816447A (en) | 1981-08-26 | 1989-03-28 | Merck & Co., Inc. | Anti-viral guanine compounds |
| NZ201662A (en) | 1981-08-26 | 1986-07-11 | Merck & Co Inc | 9-(1,3-(and 2,3)-dihydroxy-1-(and 2)-propoxy-methyl)guanine derivatives and methods for their preparation |
| US5250535A (en) * | 1982-02-01 | 1993-10-05 | Syntex Inc. | Substituted 9-(1 or 3-monoacyloxy or 1,3-diacyloxy-2-propoxymethyl) purines as antiviral agent |
| US4556659A (en) * | 1982-08-09 | 1985-12-03 | Syntex (U.S.A.) Inc. | Substituted 9-(1-0- or 3-0-monosubstituted or 1,3-Di-0-substituted propoxymethyl)-purines as antiviral agents |
| JPH0655755B2 (ja) | 1985-01-23 | 1994-07-27 | 富山化学工業株式会社 | 新規な５−フルオロ−２′−デオキシウリジン−３′−ホスフエ−ト誘導体およびその塩 |
| US4684631A (en) | 1984-10-09 | 1987-08-04 | Toyama Chemical Co., Ltd. | Novel 5-fluoro-2-deoxyuridine derivatives and salts thereof, process for producing the same, and antitumor agents containing the same |
| US5223263A (en) * | 1988-07-07 | 1993-06-29 | Vical, Inc. | Liponucleotide-containing liposomes |
| JPS6483092A (en) | 1987-09-24 | 1989-03-28 | Arakawa Chotaro & Co | Novel n6,n6-dimethyladenosine derivative having carcinostatic activity, its production and carcinostatic agent containing said derivative as active component |
| EP0355131B1 (en) * | 1987-10-28 | 1996-09-04 | Pro-Neuron, Inc. | Acyl deoxyribonucleoside derivatives and uses thereof |
| JPH0278696A (ja) | 1988-09-13 | 1990-03-19 | Shoichiro Ozaki | ５−フルオロウラシル誘導体 |
| US5216142A (en) * | 1989-04-17 | 1993-06-01 | Efamol Holdings Plc | Anti-virals |
| RU2085557C1 (ru) * | 1991-09-30 | 1997-07-27 | Санкио Компани Лимитед | Производные нуклеозидов пиримидина или их фармацевтически приемлемые соли и способ их получения |
-
1991
- 1991-10-07 GB GB9121257A patent/GB2260319B/en not_active Expired - Fee Related
-
1992
- 1992-09-28 ZA ZA927432A patent/ZA927432B/xx unknown
- 1992-09-29 NZ NZ244535A patent/NZ244535A/en not_active IP Right Cessation
- 1992-09-30 CH CH92922008.5T patent/CH0642525H1/xx unknown
- 1992-09-30 CA CA002120725A patent/CA2120725C/en not_active Expired - Lifetime
- 1992-09-30 US US08/211,386 patent/US6548486B1/en not_active Expired - Lifetime
- 1992-09-30 AT AT92922008T patent/ATE152454T1/de active
- 1992-09-30 RU RU94021110/04A patent/RU2126417C1/ru active
- 1992-09-30 EP EP92922008A patent/EP0642525B1/en not_active Expired - Lifetime
- 1992-09-30 CZ CZ1994805A patent/CZ288153B6/cs not_active IP Right Cessation
- 1992-09-30 DE DE69219482T patent/DE69219482T2/de not_active Expired - Lifetime
- 1992-09-30 HU HU9400988A patent/HU219400B/hu unknown
- 1992-09-30 SG SG1996004250A patent/SG47759A1/en unknown
- 1992-09-30 KR KR1019940701120A patent/KR100272732B1/ko not_active IP Right Cessation
- 1992-09-30 WO PCT/NO1992/000162 patent/WO1993007163A1/en active IP Right Grant
- 1992-09-30 SK SK397-94A patent/SK281903B6/sk not_active IP Right Cessation
- 1992-09-30 UA UA94005489A patent/UA41296C2/uk unknown
- 1992-09-30 PL PL92303098A patent/PL170846B1/pl unknown
- 1992-09-30 JP JP5506814A patent/JP2873313B2/ja not_active Expired - Lifetime
- 1992-09-30 DK DK92922008.5T patent/DK0642525T3/da active
- 1992-10-03 TW TW081107870A patent/TW347333B/zh not_active IP Right Cessation
- 1992-10-05 IL IL10335192A patent/IL103351A/xx not_active IP Right Cessation
- 1992-10-06 MX MX9205715A patent/MX9205715A/es unknown
-
1994
- 1994-04-06 FI FI941574A patent/FI105035B/fi not_active IP Right Cessation
- 1994-04-07 NO NO941269A patent/NO300014B1/no not_active IP Right Cessation
-
1997
- 1997-07-16 GR GR970401799T patent/GR3024149T3/el unknown
-
1998
- 1998-06-17 HK HK98105563A patent/HK1007430A1/xx not_active IP Right Cessation
-
1999
- 1999-02-10 FI FI990270A patent/FI990270A0/fi unknown
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