FI990270A0 - Uuden monoesteriyhdisteet - Google Patents

Uuden monoesteriyhdisteet

Info

Publication number
FI990270A0
FI990270A0 FI990270A FI990270A FI990270A0 FI 990270 A0 FI990270 A0 FI 990270A0 FI 990270 A FI990270 A FI 990270A FI 990270 A FI990270 A FI 990270A FI 990270 A0 FI990270 A0 FI 990270A0
Authority
FI
Finland
Prior art keywords
acid
nucleosides
fatty acid
new
ara
Prior art date
Application number
FI990270A
Other languages
English (en)
Swedish (sv)
Other versions
FI990270A (fi
Inventor
Are Dalen
Finn Myhren
Bernt Boerretzen
Kjell Torgeir Stokke
Original Assignee
Norsk Hydro As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Norsk Hydro As filed Critical Norsk Hydro As
Publication of FI990270A publication Critical patent/FI990270A/fi
Publication of FI990270A0 publication Critical patent/FI990270A0/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • External Artificial Organs (AREA)
  • Mechanical Coupling Of Light Guides (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
FI990270A 1991-10-07 1999-02-10 Uuden monoesteriyhdisteet FI990270A0 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9121257A GB2260319B (en) 1991-10-07 1991-10-07 Acyl derivatives of nucleosides and nucleoside analogues having anti-viral activity
PCT/NO1992/000162 WO1993007163A1 (en) 1991-10-07 1992-09-30 Chemical compounds

Publications (2)

Publication Number Publication Date
FI990270A FI990270A (fi) 1999-02-10
FI990270A0 true FI990270A0 (fi) 1999-02-10

Family

ID=10702531

Family Applications (2)

Application Number Title Priority Date Filing Date
FI941574A FI105035B (fi) 1991-10-07 1994-04-06 Menetelmä uuden, terapeuttisesti aktiivisen monoesteriyhdisteen valmistamiseksi
FI990270A FI990270A0 (fi) 1991-10-07 1999-02-10 Uuden monoesteriyhdisteet

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FI941574A FI105035B (fi) 1991-10-07 1994-04-06 Menetelmä uuden, terapeuttisesti aktiivisen monoesteriyhdisteen valmistamiseksi

Country Status (27)

Country Link
US (1) US6548486B1 (fi)
EP (1) EP0642525B1 (fi)
JP (1) JP2873313B2 (fi)
KR (1) KR100272732B1 (fi)
AT (1) ATE152454T1 (fi)
CA (1) CA2120725C (fi)
CH (1) CH0642525H1 (fi)
CZ (1) CZ288153B6 (fi)
DE (1) DE69219482T2 (fi)
DK (1) DK0642525T3 (fi)
FI (2) FI105035B (fi)
GB (1) GB2260319B (fi)
GR (1) GR3024149T3 (fi)
HK (1) HK1007430A1 (fi)
HU (1) HU219400B (fi)
IL (1) IL103351A (fi)
MX (1) MX9205715A (fi)
NO (1) NO300014B1 (fi)
NZ (1) NZ244535A (fi)
PL (1) PL170846B1 (fi)
RU (1) RU2126417C1 (fi)
SG (1) SG47759A1 (fi)
SK (1) SK281903B6 (fi)
TW (1) TW347333B (fi)
UA (1) UA41296C2 (fi)
WO (1) WO1993007163A1 (fi)
ZA (1) ZA927432B (fi)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9307043D0 (en) * 1993-04-05 1993-05-26 Norsk Hydro As Chemical compounds
US6703394B2 (en) 1996-02-16 2004-03-09 Medivir Ab Acyclic nucleoside derivatives
US5869493A (en) 1996-02-16 1999-02-09 Medivir Ab Acyclic nucleoside derivatives
GB2321455A (en) * 1997-01-24 1998-07-29 Norsk Hydro As Lipophilic derivatives of biologically active compounds
GB0201179D0 (en) * 2002-01-18 2002-03-06 Angeletti P Ist Richerche Bio Therapeutic agents
TWI332507B (en) 2002-11-19 2010-11-01 Hoffmann La Roche Antiviral nucleoside derivatives
US8114847B2 (en) 2005-03-16 2012-02-14 Case Western Reserve University Selective inhibitors of translesion DNA replication
WO2008147454A1 (en) * 2006-11-16 2008-12-04 Case Western Reserve University Selective inhibitors of translesion dna replication
NO324263B1 (no) * 2005-12-08 2007-09-17 Clavis Pharma Asa Kjemiske forbindelser, anvendelse derav ved behandling av kreft, samt farmasoytiske preparater som omfatter slike forbindelser
US8497292B2 (en) * 2005-12-28 2013-07-30 Translational Therapeutics, Inc. Translational dysfunction based therapeutics
WO2008150438A1 (en) * 2007-06-01 2008-12-11 Luitpold Pharmaceuticals, Inc. Pmea lipid conjugates
CA2717788A1 (en) 2007-07-09 2009-01-15 Eastern Virginia Medical School Substituted nucleoside derivatives with antiviral and antimicrobial properties
KR20100072230A (ko) * 2007-09-26 2010-06-30 마운트 시나이 스쿨 오브 메디신 오브 뉴욕 유니버시티 아자시티딘 유사체 및 이의 용도
US9988680B2 (en) 2011-09-01 2018-06-05 Case Western Reserve University Non-natural nucleosides as theranostic agents
US9493500B2 (en) 2012-07-19 2016-11-15 Richard Daifuku Fluorinated pyrimidine analogs and methods of use thereof
US9821173B2 (en) 2013-02-08 2017-11-21 Case Western Reserve University Anti-cancer agents and methods of use
RU2621145C2 (ru) * 2015-11-03 2017-05-31 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Воронежский государственный университет" (ФГБОУ ВПО "ВГУ") Способ получения липосом
US20200407393A1 (en) * 2018-03-07 2020-12-31 Glaxosmithkline Intellectual Property (No. 2) Limited Medical Use

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3920630A (en) 1970-09-24 1975-11-18 Upjohn Co 2,2{40 -Anhydro-ara-cytidine compounds and process of preparation
GB1325798A (en) 1970-09-24 1973-08-08 Upjohn Co Derivatives of 2,2-anhydro-ara-cytidine
US4211773A (en) * 1978-10-02 1980-07-08 Sloan Kettering Institute For Cancer Research 5-Substituted 1-(2'-Deoxy-2'-substituted-β-D-arabinofuranosyl)pyrimidine nucleosides
DE3100478A1 (de) 1981-01-09 1982-08-12 Dr. Thilo & Co GmbH, 8021 Sauerlach 5'ester von pyrimidinnucleosiden mit antiviraler wirksamkeit, verfahren zur herstellung und daraus hergestellte arzneimittel
US4355032B2 (en) 1981-05-21 1990-10-30 9-(1,3-dihydroxy-2-propoxymethyl)guanine as antiviral agent
US4816447A (en) 1981-08-26 1989-03-28 Merck & Co., Inc. Anti-viral guanine compounds
NZ201662A (en) 1981-08-26 1986-07-11 Merck & Co Inc 9-(1,3-(and 2,3)-dihydroxy-1-(and 2)-propoxy-methyl)guanine derivatives and methods for their preparation
US5250535A (en) * 1982-02-01 1993-10-05 Syntex Inc. Substituted 9-(1 or 3-monoacyloxy or 1,3-diacyloxy-2-propoxymethyl) purines as antiviral agent
US4556659A (en) * 1982-08-09 1985-12-03 Syntex (U.S.A.) Inc. Substituted 9-(1-0- or 3-0-monosubstituted or 1,3-Di-0-substituted propoxymethyl)-purines as antiviral agents
US4684631A (en) 1984-10-09 1987-08-04 Toyama Chemical Co., Ltd. Novel 5-fluoro-2-deoxyuridine derivatives and salts thereof, process for producing the same, and antitumor agents containing the same
JPH0655755B2 (ja) 1985-01-23 1994-07-27 富山化学工業株式会社 新規な５−フルオロ−２′−デオキシウリジン−３′−ホスフエ−ト誘導体およびその塩
US5223263A (en) 1988-07-07 1993-06-29 Vical, Inc. Liponucleotide-containing liposomes
JPS6483092A (en) 1987-09-24 1989-03-28 Arakawa Chotaro & Co Novel n6,n6-dimethyladenosine derivative having carcinostatic activity, its production and carcinostatic agent containing said derivative as active component
CA1329932C (en) * 1987-10-28 1994-05-31 Reid Von Borstel Acyl deoxyribonucleoside derivatives and uses thereof
JPH0278696A (ja) 1988-09-13 1990-03-19 Shoichiro Ozaki ５−フルオロウラシル誘導体
US5216142A (en) * 1989-04-17 1993-06-01 Efamol Holdings Plc Anti-virals
CA2079413C (en) * 1991-09-30 2003-09-09 Masakatsu Kaneko Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use

Also Published As

Publication number Publication date
HUT68008A (en) 1995-05-29
GB2260319B (en) 1995-12-06
HU219400B (hu) 2001-04-28
KR100272732B1 (ko) 2000-11-15
CA2120725A1 (en) 1993-04-15
IL103351A (en) 2000-02-17
UA41296C2 (uk) 2001-09-17
DK0642525T3 (da) 1997-11-03
MX9205715A (es) 1993-05-01
FI105035B (fi) 2000-05-31
AU2867392A (en) 1993-05-03
NO941269D0 (no) 1994-04-07
TW347333B (en) 1998-12-11
AU672369B2 (en) 1996-10-03
ZA927432B (en) 1993-06-09
ATE152454T1 (de) 1997-05-15
NZ244535A (en) 1995-08-28
GB9121257D0 (en) 1991-11-20
FI941574A0 (fi) 1994-04-06
SK281903B6 (sk) 2001-09-11
SG47759A1 (en) 1998-04-17
GR3024149T3 (en) 1997-10-31
GB2260319A (en) 1993-04-14
SK39794A3 (en) 1994-10-05
CA2120725C (en) 2000-04-11
US6548486B1 (en) 2003-04-15
EP0642525A1 (en) 1995-03-15
JP2873313B2 (ja) 1999-03-24
FI990270A (fi) 1999-02-10
WO1993007163A1 (en) 1993-04-15
CZ288153B6 (en) 2001-05-16
EP0642525B1 (en) 1997-05-02
IL103351A0 (en) 1993-03-15
RU2126417C1 (ru) 1999-02-20
CZ80594A3 (en) 1994-12-15
NO300014B1 (no) 1997-03-17
PL170846B1 (en) 1997-01-31
HK1007430A1 (en) 1999-04-09
FI941574A (fi) 1994-04-06
JPH06511249A (ja) 1994-12-15
DE69219482T2 (de) 1997-10-23
DE69219482D1 (de) 1997-06-05
CH0642525H1 (en) 1999-06-30
NO941269L (no) 1994-04-07
HU9400988D0 (en) 1994-07-28

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