NO934140D0 - Krystallinske carbapenemderivat - Google Patents

Krystallinske carbapenemderivat

Info

Publication number
NO934140D0
NO934140D0 NO934140A NO934140A NO934140D0 NO 934140 D0 NO934140 D0 NO 934140D0 NO 934140 A NO934140 A NO 934140A NO 934140 A NO934140 A NO 934140A NO 934140 D0 NO934140 D0 NO 934140D0
Authority
NO
Norway
Prior art keywords
carbapenem derivative
crystalline carbapenem
crystalline
derivative
pyrrolidinylthio
Prior art date
Application number
NO934140A
Other languages
English (en)
Other versions
NO934140L (no
NO304431B1 (no
Inventor
Isao Kawamoto
Masao Miyauchi
Rokuro Endo
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co filed Critical Sankyo Co
Publication of NO934140D0 publication Critical patent/NO934140D0/no
Publication of NO934140L publication Critical patent/NO934140L/no
Publication of NO304431B1 publication Critical patent/NO304431B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
NO934140A 1992-11-17 1993-11-16 Krystallinsk karbapenemderivat og farmas°ytisk preparat omfattende dette NO304431B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP30688492 1992-11-17
JP17026793 1993-07-09

Publications (3)

Publication Number Publication Date
NO934140D0 true NO934140D0 (no) 1993-11-16
NO934140L NO934140L (no) 1994-05-18
NO304431B1 NO304431B1 (no) 1998-12-14

Family

ID=26493307

Family Applications (1)

Application Number Title Priority Date Filing Date
NO934140A NO304431B1 (no) 1992-11-17 1993-11-16 Krystallinsk karbapenemderivat og farmas°ytisk preparat omfattende dette

Country Status (21)

Country Link
US (1) US5424306A (no)
EP (1) EP0599512B1 (no)
JP (1) JP2848552B2 (no)
KR (1) KR100236845B1 (no)
CN (1) CN1036714C (no)
AT (1) ATE178066T1 (no)
AU (1) AU677235B2 (no)
CA (1) CA2103223C (no)
CZ (1) CZ280507B6 (no)
DE (1) DE69324106T2 (no)
DK (1) DK0599512T3 (no)
ES (1) ES2131560T3 (no)
FI (1) FI103576B (no)
GR (1) GR3029975T3 (no)
HK (1) HK1011977A1 (no)
HU (1) HU219582B (no)
IL (1) IL107596A (no)
NO (1) NO304431B1 (no)
NZ (1) NZ250201A (no)
PH (1) PH30464A (no)
TW (1) TW360657B (no)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2180972T3 (es) * 1996-05-09 2003-02-16 Sankyo Co Composicion contra el helicobacter pilori que contiene derivados de 1-metilcarbapenem como ingrediente activo.
TWI250160B (en) 1999-07-06 2006-03-01 Sankyo Co Crystalline 1-methylcarbapenem compound
US7041660B2 (en) * 1999-07-06 2006-05-09 Sankyo Company, Limited Crystalline 1-methylcarbapenem derivatives
KR100451672B1 (ko) * 2001-06-05 2004-10-08 한미약품 주식회사 결정성 세프디니르 산부가염, 이의 제조방법 및 이를이용한 세프디니르의 제조방법
ITMI20012364A1 (it) * 2001-11-09 2003-05-09 Antibioticos Spa Processo di sintesi della cefixima via alchil-o arilsolfonati
IL163666A0 (en) 2002-02-22 2005-12-18 New River Pharmaceuticals Inc Active agent delivery systems and methods for protecting and administering active agents
AU2003301425A1 (en) * 2002-10-18 2004-05-04 Meiji Seika Kaisha, Ltd. Process for producing carbapenem derivative and intermediate for use in the production
JP2008501657A (ja) * 2004-06-02 2008-01-24 サンド・アクチエンゲゼルシヤフト 結晶形態のメロペネム中間体
JP2009143808A (ja) * 2006-03-28 2009-07-02 Kaneka Corp メロペネム中間体の単離方法
JP5715339B2 (ja) 2007-01-12 2015-05-07 ノバルティス アーゲー ５−ビフェニル−４−アミノ−２−メチルペンタン酸の製造方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5242914A (en) * 1988-04-01 1993-09-07 Sankyo Company, Limited 2-(heterocyclylthio) carbapenem derivatives, their preparation and their use as antibiotics
IE950607L (en) * 1988-04-01 1989-10-01 Sankyo Co 2-(heterocyclylthio) carbapenem derivatives, their¹preparation and their use as antibiotics
JPH0745499B2 (ja) * 1988-05-10 1995-05-17 三共株式会社 １―メチルカルバペネム誘導体
EP0462521A1 (en) * 1990-06-19 1991-12-27 Takeda Chemical Industries, Ltd. Crystalline penem, its production and use

Also Published As

Publication number Publication date
EP0599512A1 (en) 1994-06-01
CN1036714C (zh) 1997-12-17
AU5063193A (en) 1994-06-02
KR100236845B1 (ko) 2000-02-01
NZ250201A (en) 1995-04-27
FI103576B1 (fi) 1999-07-30
IL107596A0 (en) 1994-02-27
EP0599512B1 (en) 1999-03-24
DK0599512T3 (da) 1999-10-11
CZ280507B6 (cs) 1996-02-14
CZ245493A3 (en) 1995-08-16
CN1093366A (zh) 1994-10-12
JP2848552B2 (ja) 1999-01-20
PH30464A (en) 1997-05-28
JPH07165759A (ja) 1995-06-27
ATE178066T1 (de) 1999-04-15
AU677235B2 (en) 1997-04-17
FI935063A (fi) 1994-05-18
TW360657B (en) 1999-06-11
HUT66001A (en) 1994-08-29
CA2103223C (en) 2002-09-24
DE69324106T2 (de) 1999-12-09
FI935063A0 (fi) 1993-11-16
HU219582B (hu) 2001-05-28
CA2103223A1 (en) 1994-05-18
GR3029975T3 (en) 1999-07-30
IL107596A (en) 1998-02-08
DE69324106D1 (de) 1999-04-29
NO934140L (no) 1994-05-18
HK1011977A1 (en) 1999-07-23
KR940011463A (ko) 1994-06-21
US5424306A (en) 1995-06-13
NO304431B1 (no) 1998-12-14
ES2131560T3 (es) 1999-08-01
FI103576B (fi) 1999-07-30

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