ES2180972T3 - Composicion contra el helicobacter pilori que contiene derivados de 1-metilcarbapenem como ingrediente activo. - Google Patents

Composicion contra el helicobacter pilori que contiene derivados de 1-metilcarbapenem como ingrediente activo.

Info

Publication number
ES2180972T3
ES2180972T3 ES97918382T ES97918382T ES2180972T3 ES 2180972 T3 ES2180972 T3 ES 2180972T3 ES 97918382 T ES97918382 T ES 97918382T ES 97918382 T ES97918382 T ES 97918382T ES 2180972 T3 ES2180972 T3 ES 2180972T3
Authority
ES
Spain
Prior art keywords
active ingredient
metilcarbapenem
composition against
containing derivatives
against helicobacter
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97918382T
Other languages
English (en)
Inventor
Isao Kawamoto
Satoshi Ohya
Yukio Utsui
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Application granted granted Critical
Publication of ES2180972T3 publication Critical patent/ES2180972T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4188—1,3-Diazoles condensed with other heterocyclic ring systems, e.g. biotin, sorbinil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/02—Preparation
    • C07D477/04—Preparation by forming the ring or condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

DERIVADOS DE 1 - METILCARBAPENEM CON LA SIGUIENTE FORMULA (EN LA QUE R 1 REPRESENTA UN GRUPO DE LA SIGUIENTE FORMULA Y R 2 REPRESENTA UN ATOMO DE HIDROGENO O UN GRUPO DE ALQUILO Y R 3 REPRESENTA UN ATOMO DE HIDROGENO O UN GRUPO DE ALQUILO), O SALES FARMACOLOGICAMENTE ACEPTABLES O ESTERES DEL MISMO QUE SON UTILES COMO INGREDIENTE ACTIVO EN UNA COMPOSICION PARA UN TRATAMIENTO ANTIHELICOBACTER PYLORI (TRATAMIENTO O PREVENCION DE ENFERMEDADES INFECCIOSAS CAUSADAS POR LA HELICOBACTER PYLORI).
ES97918382T 1996-05-09 1997-05-08 Composicion contra el helicobacter pilori que contiene derivados de 1-metilcarbapenem como ingrediente activo. Expired - Lifetime ES2180972T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP11444896 1996-05-09

Publications (1)

Publication Number Publication Date
ES2180972T3 true ES2180972T3 (es) 2003-02-16

Family

ID=14637995

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97918382T Expired - Lifetime ES2180972T3 (es) 1996-05-09 1997-05-08 Composicion contra el helicobacter pilori que contiene derivados de 1-metilcarbapenem como ingrediente activo.

Country Status (17)

Country Link
US (1) US6180621B1 (es)
EP (1) EP0913151B1 (es)
KR (1) KR20000005535A (es)
CN (1) CN1101189C (es)
AT (1) ATE223216T1 (es)
AU (1) AU711128C (es)
CA (1) CA2253860A1 (es)
CZ (1) CZ287902B6 (es)
DE (1) DE69715208T2 (es)
DK (1) DK0913151T3 (es)
ES (1) ES2180972T3 (es)
HK (1) HK1019710A1 (es)
NO (1) NO985202L (es)
NZ (1) NZ332687A (es)
PT (1) PT913151E (es)
RU (1) RU2173147C2 (es)
WO (1) WO1997041853A1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11335269A (ja) * 1998-05-19 1999-12-07 Hisamitsu Pharmaceut Co Inc 遺伝子関連医薬の経口投与固形製剤
US6479478B1 (en) * 1998-09-10 2002-11-12 Wyeth Lederle Japan, Ltd. Carbapenem compounds
MXPA02007134A (es) * 2000-01-18 2003-03-27 Vertex Pharma Inhibidores de girasa y usos de los mismos.
WO2002072102A1 (en) * 2001-03-05 2002-09-19 Ortho-Mcneil Pharmaceutical, Inc. Taste masked liquid pharmaceutical compositions
US7670624B2 (en) * 2004-01-29 2010-03-02 Astella Pharma Inc. Gastrointestinal-specific multiple drug release system
CN101260108B (zh) * 2007-03-11 2010-06-02 山东轩竹医药科技有限公司 巯基吡咯烷酮碳青霉烯类衍生物
US10519161B2 (en) 2012-10-29 2019-12-31 Southern Methodist University Methods of generating beta-lactamase resistant carbapenem compounds
US9394634B2 (en) 2014-03-20 2016-07-19 Arun Agarwal Woven shielding textile impervious to visible and ultraviolet electromagnetic radiation

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2708576B2 (ja) 1988-11-08 1998-02-04 第一製薬株式会社 カルバペネム誘導体
CA2050255C (en) * 1990-09-07 1997-02-04 Tameo Iwasaki 1-methylcarbapenem derivatives and process for preparation thereof
FI920206A0 (fi) * 1992-01-17 1992-01-17 Pekka Untamo Heino Medicinsk anvaendning, medicinskt foerfarande och preparat.
DK0599512T3 (da) * 1992-11-17 1999-10-11 Sankyo Co Krystallinsk carbapenemderivat
AU682510B2 (en) 1993-07-01 1997-10-09 Pfizer Japan Inc. 2-(1-(1,3-thiazolin-2-yl)azetidin-3-yl)thio-carbapenem derivatives
JP3266994B2 (ja) 1993-07-28 2002-03-18 株式会社ニコン 反射型マスク
JPH07126189A (ja) * 1993-09-09 1995-05-16 Takeda Chem Ind Ltd 抗潰瘍併用療法用製剤
DE69424487T2 (de) * 1993-09-09 2001-01-18 Takeda Chemical Industries Ltd Formulierung enthaltend einen antibakteriellen und einen Antiulcus Wirkstoff

Also Published As

Publication number Publication date
AU2651597A (en) 1997-11-26
WO1997041853A1 (fr) 1997-11-13
CN1225011A (zh) 1999-08-04
RU2173147C2 (ru) 2001-09-10
EP0913151B1 (en) 2002-09-04
DE69715208D1 (de) 2002-10-10
NZ332687A (en) 2000-05-26
EP0913151A4 (en) 2001-01-17
AU711128C (en) 2002-11-07
CZ287902B6 (cs) 2001-03-14
CN1101189C (zh) 2003-02-12
AU711128B2 (en) 1999-10-07
ATE223216T1 (de) 2002-09-15
NO985202D0 (no) 1998-11-06
CZ363598A3 (cs) 1999-04-14
EP0913151A1 (en) 1999-05-06
DK0913151T3 (da) 2002-10-14
NO985202L (no) 1999-01-08
DE69715208T2 (de) 2003-04-17
HK1019710A1 (en) 2000-02-25
KR20000005535A (ko) 2000-01-25
US6180621B1 (en) 2001-01-30
CA2253860A1 (en) 1997-11-13
PT913151E (pt) 2002-11-29

Similar Documents

Publication Publication Date Title
EP0513387A4 (en) Active oxygen inhibitor
ATE260255T1 (de) 5-oxo-pyrrolidine-2-carbonsäure- hydroxamidderivate
ES2182852T3 (es) Derivados de prolinamida.
PT928788E (pt) Compostos farmaceuticamente activos
AU4396899A (en) Remedies for diabetes
EA200100916A1 (ru) Лекарственное средство, содержащее производное сульфопиранозилацилглицерина
PT916651E (pt) DERIVADOS DE áCIDO FENILALQUILCARBOXILICO
ES2180972T3 (es) Composicion contra el helicobacter pilori que contiene derivados de 1-metilcarbapenem como ingrediente activo.
MX9805023A (es) Derivados de 1-metilcarbapenem.
HU9202852D0 (en) Insecticidal and acaricidal preparatives containing derivatives of n-alkanoil-amino-methyl and of n-aroil-amino-methyl-pyrrole as active agent and method for producing said compounds
BRPI0317188A2 (pt) Novo derivado de 2,4-diamino-1,3,5-triazina
DE60009517D1 (de) A-500359-derivate
TW280810B (es)
NO993911D0 (no) Remedier/Forebygningsmidler for åndedrettssykdommer
EP1500656A4 (en) BIGUANIDE DERIVATIVE AND DIABETES TREATMENT AGENT CONTAINING
MX9704976A (es) Derivados de 1,2,3-benzotiadiazol.