NO933615L - Tiazolidindionderivater, fremstilling og anvendelse derav - Google Patents

Tiazolidindionderivater, fremstilling og anvendelse derav

Info

Publication number
NO933615L
NO933615L NO933615A NO933615A NO933615L NO 933615 L NO933615 L NO 933615L NO 933615 A NO933615 A NO 933615A NO 933615 A NO933615 A NO 933615A NO 933615 L NO933615 L NO 933615L
Authority
NO
Norway
Prior art keywords
preparation
thiazolidinedione derivatives
general formula
thiazolidinedione derivative
thiazolidinedione
Prior art date
Application number
NO933615A
Other languages
English (en)
Norwegian (no)
Other versions
NO933615D0 (no
Inventor
Takashi Sohda
Hitoshi Ikeda
John C Greenfield
Jerry R Colca
Edgar R Petzold
Original Assignee
Upjohn Co
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=13672917&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO933615(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Upjohn Co, Takeda Chemical Industries Ltd filed Critical Upjohn Co
Publication of NO933615D0 publication Critical patent/NO933615D0/no
Publication of NO933615L publication Critical patent/NO933615L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Graft Or Block Polymers (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Lubricants (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO933615A 1991-04-11 1993-10-08 Tiazolidindionderivater, fremstilling og anvendelse derav NO933615L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP7883691 1991-04-11
PCT/US1992/002566 WO1992018501A1 (en) 1991-04-11 1992-04-06 Thiazolidinedione derivatives, production and use thereof

Publications (2)

Publication Number Publication Date
NO933615D0 NO933615D0 (no) 1993-10-08
NO933615L true NO933615L (no) 1993-10-08

Family

ID=13672917

Family Applications (1)

Application Number Title Priority Date Filing Date
NO933615A NO933615L (no) 1991-04-11 1993-10-08 Tiazolidindionderivater, fremstilling og anvendelse derav

Country Status (19)

Country Link
EP (1) EP0579733B1 (ko)
JP (1) JP3176694B2 (ko)
KR (1) KR100249988B1 (ko)
AT (1) ATE202352T1 (ko)
AU (1) AU1743292A (ko)
CA (1) CA2106967C (ko)
CZ (1) CZ196693A3 (ko)
DE (1) DE69231886T2 (ko)
DK (1) DK0579733T3 (ko)
ES (1) ES2161692T3 (ko)
FI (1) FI934426A0 (ko)
GR (1) GR3036623T3 (ko)
HU (1) HUT68370A (ko)
MX (1) MX9201637A (ko)
NO (1) NO933615L (ko)
PT (1) PT100366A (ko)
SK (1) SK109993A3 (ko)
TW (1) TW209864B (ko)
WO (1) WO1992018501A1 (ko)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993022445A1 (en) * 1992-05-05 1993-11-11 The Upjohn Company A process for producing pioglitazone metabolite
TW268952B (ko) * 1993-02-26 1996-01-21 Takeda Pharm Industry Co Ltd
NO305987B1 (no) * 1994-04-11 1999-08-30 Sankyo Co Heterosykliske forbindelser med antidiabetisk aktivitet, deres anvendelse og farmasoeytisk preparat inneholdende disse
US5952509A (en) * 1996-06-27 1999-09-14 Takeda Chemical Industries, Ltd. Production of benzaldehyde compounds
ATE353654T1 (de) 1997-06-18 2007-03-15 Smithkline Beecham Plc Behandlung der diabetes mit thiazolidindione und sulphonylurea
AR023700A1 (es) 1998-11-12 2002-09-04 Smithkline Beecham Plc Un procedimiento para preparar una composicion farmaceutica que comprende un sensibilizador de insulina
JP2002529504A (ja) 1998-11-12 2002-09-10 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー インスリン感作物質および他の抗糖尿病薬の放出修飾のための医薬組成物
GB0014969D0 (en) 2000-06-19 2000-08-09 Smithkline Beecham Plc Novel method of treatment
DE20119200U1 (de) 2001-11-27 2003-04-10 Winklhofer & Soehne Gmbh Kettenspanner mit mechanischer Verriegelung
US8268352B2 (en) 2002-08-05 2012-09-18 Torrent Pharmaceuticals Limited Modified release composition for highly soluble drugs
US8216609B2 (en) 2002-08-05 2012-07-10 Torrent Pharmaceuticals Limited Modified release composition of highly soluble drugs
KR100646128B1 (ko) 2005-04-21 2006-11-14 전라옥 PPARγ에 선택적으로 작용하는 테트라하이드로퀴놀린계열 티아졸리딘디온 유도체 및 그 합성방법
ES2654908T3 (es) * 2006-03-16 2018-02-15 Metabolic Solutions Development Company Llc Análogos de tiazolidindiona para el tratamiento de enfermedades mediadas por una inflamación metabólica
ES2388555T3 (es) 2006-03-16 2012-10-16 Metabolic Solutions Development Company Llc Análogos de tiazolidindiona
CA2646170A1 (en) * 2006-03-16 2007-09-27 Metabolic Solutions Development Company Combination therapies of thiazolidinedione analogues and glucocorticoid agonists
AU2013200104B2 (en) * 2006-03-16 2014-05-15 Metabolic Solutions Development Company, Llc Thiazolidinedione analogues for the treatment of metabolic inflammation mediated disease
US7435741B2 (en) 2006-05-09 2008-10-14 Teva Pharmaceutical Industries, Ltd. 2-N{5-[[4-[2-(methyl-2-pyridinylamino) ethoxy] phenyl]methyl]-2,4-thiazolidinedione} butanedioic acid, methods of preparation and compositions with rosiglitazone maleate
WO2008038359A1 (fr) 2006-09-28 2008-04-03 Daido Kogyo Co., Ltd. Tensionneur de chaîne
US8304441B2 (en) 2007-09-14 2012-11-06 Metabolic Solutions Development Company, Llc Thiazolidinedione analogues for the treatment of metabolic diseases
ES2398313T3 (es) 2007-09-14 2013-03-15 Metabolic Solutions Development Company Llc 5-(4-(2-(3-metoxifenil)-2-oxoetoxi)bencil)tiazolidin-2,4-diona para uso en el tratamiento de la diabetes
US8722710B2 (en) 2007-09-26 2014-05-13 Deuterx, Llc Deuterium-enriched pioglitazone
MX2012006725A (es) * 2009-12-15 2012-06-28 Metabolic Solutions Dev Co Llc Sales de tiazolidinadiona reductoras de receptores activados por proliferador de peroxisoma (ppar) para el tratamiento de enfermedades metabolicas.
EP2563767A2 (en) * 2010-04-19 2013-03-06 Metabolic Solutions Development Company LLC Novel synthesis for thiazolidinedione compounds
ES2610623T3 (es) * 2010-04-19 2017-04-28 Octeta Therapeutics, Llc Nueva síntesis de compuestos de tiazolidindiona
WO2012021476A1 (en) 2010-08-10 2012-02-16 Metabolic Solutions Development Company, Llc Novel synthesis for thiazolidinedione compounds
CN103153991B (zh) * 2010-08-10 2016-06-29 新陈代谢解决方案开发公司 噻唑烷二酮化合物的合成方法
US20120094959A1 (en) 2010-10-19 2012-04-19 Bonnie Blazer-Yost Treatment of cystic diseases
CA2941562C (en) * 2013-03-14 2021-09-21 Deuterx, Llc Deuterium-enriched 2,4-thiazolidinediones and methods of treatment
EP3094328B1 (en) 2014-01-15 2020-08-19 Poxel SA Methods of treating neurological, metabolic, and other disorders using enantiopure deuterium-enriched pioglitazone
SI3388064T1 (sl) * 2014-04-02 2021-08-31 Minoryx Therapeutics S.L. Derivati 2,4-tiazolidindiona pri zdravljenju motenj centralnega živčnega sistema
US10034868B2 (en) 2014-11-04 2018-07-31 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for the prevention and the treatment of rapidly progressive glomerulonephritis
WO2018100557A1 (en) 2016-12-01 2018-06-07 Minoryx Therapeutics S.L. 5-[[4-[2-[5-(1-hydroxyethyl)pyridin-2-yl]ethoxy]phenyl]methyl]-1,3-thiazolidine- 2,4-dione for treating nonalcoholic fatty liver disease
PL3559010T3 (pl) 2016-12-23 2022-11-21 Minoryx Therapeutics S.L. Sposób wytwarzania 5-[[4-[2-[5-(1-hydroksyetylo)-2-pirydynylo]etoksy]fenylo]metylo]-2,4-tiazolidynodionu i jego soli
US11319313B2 (en) 2020-06-30 2022-05-03 Poxel Sa Crystalline forms of deuterium-enriched pioglitazone
US11767317B1 (en) 2020-06-30 2023-09-26 Poxel Sa Methods of synthesizing enantiopure deuterium-enriched pioglitazone

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5522636A (en) * 1978-08-04 1980-02-18 Takeda Chem Ind Ltd Thiazoliding derivative
AR240698A1 (es) * 1985-01-19 1990-09-28 Takeda Chemical Industries Ltd Procedimiento para preparar compuestos de 5-(4-(2-(5-etil-2-piridil)-etoxi)benzil)-2,4-tiazolidindiona y sus sales

Also Published As

Publication number Publication date
TW209864B (ko) 1993-07-21
KR100249988B1 (ko) 2000-04-01
NO933615D0 (no) 1993-10-08
DE69231886D1 (de) 2001-07-26
MX9201637A (es) 1993-08-01
DE69231886T2 (de) 2002-03-28
JP3176694B2 (ja) 2001-06-18
GR3036623T3 (en) 2001-12-31
SK109993A3 (en) 1994-12-07
PT100366A (pt) 1993-06-30
HUT68370A (en) 1995-06-28
CA2106967C (en) 2003-12-09
WO1992018501A1 (en) 1992-10-29
FI934426A (fi) 1993-10-08
JPH0586057A (ja) 1993-04-06
DK0579733T3 (da) 2001-10-15
EP0579733B1 (en) 2001-06-20
CZ196693A3 (en) 1994-05-18
AU1743292A (en) 1992-11-17
CA2106967A1 (en) 1992-10-12
EP0579733A1 (en) 1994-01-26
ATE202352T1 (de) 2001-07-15
ES2161692T3 (es) 2001-12-16
FI934426A0 (fi) 1993-10-08

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