NO933615L - Tiazolidindionderivater, fremstilling og anvendelse derav - Google Patents
Tiazolidindionderivater, fremstilling og anvendelse deravInfo
- Publication number
- NO933615L NO933615L NO933615A NO933615A NO933615L NO 933615 L NO933615 L NO 933615L NO 933615 A NO933615 A NO 933615A NO 933615 A NO933615 A NO 933615A NO 933615 L NO933615 L NO 933615L
- Authority
- NO
- Norway
- Prior art keywords
- preparation
- thiazolidinedione derivatives
- general formula
- thiazolidinedione derivative
- thiazolidinedione
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Graft Or Block Polymers (AREA)
- Photoreceptors In Electrophotography (AREA)
- Lubricants (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP7883691 | 1991-04-11 | ||
PCT/US1992/002566 WO1992018501A1 (en) | 1991-04-11 | 1992-04-06 | Thiazolidinedione derivatives, production and use thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
NO933615D0 NO933615D0 (no) | 1993-10-08 |
NO933615L true NO933615L (no) | 1993-10-08 |
Family
ID=13672917
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO933615A NO933615L (no) | 1991-04-11 | 1993-10-08 | Tiazolidindionderivater, fremstilling og anvendelse derav |
Country Status (19)
Country | Link |
---|---|
EP (1) | EP0579733B1 (ko) |
JP (1) | JP3176694B2 (ko) |
KR (1) | KR100249988B1 (ko) |
AT (1) | ATE202352T1 (ko) |
AU (1) | AU1743292A (ko) |
CA (1) | CA2106967C (ko) |
CZ (1) | CZ196693A3 (ko) |
DE (1) | DE69231886T2 (ko) |
DK (1) | DK0579733T3 (ko) |
ES (1) | ES2161692T3 (ko) |
FI (1) | FI934426A0 (ko) |
GR (1) | GR3036623T3 (ko) |
HU (1) | HUT68370A (ko) |
MX (1) | MX9201637A (ko) |
NO (1) | NO933615L (ko) |
PT (1) | PT100366A (ko) |
SK (1) | SK109993A3 (ko) |
TW (1) | TW209864B (ko) |
WO (1) | WO1992018501A1 (ko) |
Families Citing this family (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1993022445A1 (en) * | 1992-05-05 | 1993-11-11 | The Upjohn Company | A process for producing pioglitazone metabolite |
TW268952B (ko) * | 1993-02-26 | 1996-01-21 | Takeda Pharm Industry Co Ltd | |
NO305987B1 (no) * | 1994-04-11 | 1999-08-30 | Sankyo Co | Heterosykliske forbindelser med antidiabetisk aktivitet, deres anvendelse og farmasoeytisk preparat inneholdende disse |
US5952509A (en) * | 1996-06-27 | 1999-09-14 | Takeda Chemical Industries, Ltd. | Production of benzaldehyde compounds |
ATE353654T1 (de) | 1997-06-18 | 2007-03-15 | Smithkline Beecham Plc | Behandlung der diabetes mit thiazolidindione und sulphonylurea |
AR023700A1 (es) | 1998-11-12 | 2002-09-04 | Smithkline Beecham Plc | Un procedimiento para preparar una composicion farmaceutica que comprende un sensibilizador de insulina |
JP2002529504A (ja) | 1998-11-12 | 2002-09-10 | スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー | インスリン感作物質および他の抗糖尿病薬の放出修飾のための医薬組成物 |
GB0014969D0 (en) | 2000-06-19 | 2000-08-09 | Smithkline Beecham Plc | Novel method of treatment |
DE20119200U1 (de) | 2001-11-27 | 2003-04-10 | Winklhofer & Soehne Gmbh | Kettenspanner mit mechanischer Verriegelung |
US8268352B2 (en) | 2002-08-05 | 2012-09-18 | Torrent Pharmaceuticals Limited | Modified release composition for highly soluble drugs |
US8216609B2 (en) | 2002-08-05 | 2012-07-10 | Torrent Pharmaceuticals Limited | Modified release composition of highly soluble drugs |
KR100646128B1 (ko) | 2005-04-21 | 2006-11-14 | 전라옥 | PPARγ에 선택적으로 작용하는 테트라하이드로퀴놀린계열 티아졸리딘디온 유도체 및 그 합성방법 |
ES2654908T3 (es) * | 2006-03-16 | 2018-02-15 | Metabolic Solutions Development Company Llc | Análogos de tiazolidindiona para el tratamiento de enfermedades mediadas por una inflamación metabólica |
ES2388555T3 (es) | 2006-03-16 | 2012-10-16 | Metabolic Solutions Development Company Llc | Análogos de tiazolidindiona |
CA2646170A1 (en) * | 2006-03-16 | 2007-09-27 | Metabolic Solutions Development Company | Combination therapies of thiazolidinedione analogues and glucocorticoid agonists |
AU2013200104B2 (en) * | 2006-03-16 | 2014-05-15 | Metabolic Solutions Development Company, Llc | Thiazolidinedione analogues for the treatment of metabolic inflammation mediated disease |
US7435741B2 (en) | 2006-05-09 | 2008-10-14 | Teva Pharmaceutical Industries, Ltd. | 2-N{5-[[4-[2-(methyl-2-pyridinylamino) ethoxy] phenyl]methyl]-2,4-thiazolidinedione} butanedioic acid, methods of preparation and compositions with rosiglitazone maleate |
WO2008038359A1 (fr) | 2006-09-28 | 2008-04-03 | Daido Kogyo Co., Ltd. | Tensionneur de chaîne |
US8304441B2 (en) | 2007-09-14 | 2012-11-06 | Metabolic Solutions Development Company, Llc | Thiazolidinedione analogues for the treatment of metabolic diseases |
ES2398313T3 (es) | 2007-09-14 | 2013-03-15 | Metabolic Solutions Development Company Llc | 5-(4-(2-(3-metoxifenil)-2-oxoetoxi)bencil)tiazolidin-2,4-diona para uso en el tratamiento de la diabetes |
US8722710B2 (en) | 2007-09-26 | 2014-05-13 | Deuterx, Llc | Deuterium-enriched pioglitazone |
MX2012006725A (es) * | 2009-12-15 | 2012-06-28 | Metabolic Solutions Dev Co Llc | Sales de tiazolidinadiona reductoras de receptores activados por proliferador de peroxisoma (ppar) para el tratamiento de enfermedades metabolicas. |
EP2563767A2 (en) * | 2010-04-19 | 2013-03-06 | Metabolic Solutions Development Company LLC | Novel synthesis for thiazolidinedione compounds |
ES2610623T3 (es) * | 2010-04-19 | 2017-04-28 | Octeta Therapeutics, Llc | Nueva síntesis de compuestos de tiazolidindiona |
WO2012021476A1 (en) | 2010-08-10 | 2012-02-16 | Metabolic Solutions Development Company, Llc | Novel synthesis for thiazolidinedione compounds |
CN103153991B (zh) * | 2010-08-10 | 2016-06-29 | 新陈代谢解决方案开发公司 | 噻唑烷二酮化合物的合成方法 |
US20120094959A1 (en) | 2010-10-19 | 2012-04-19 | Bonnie Blazer-Yost | Treatment of cystic diseases |
CA2941562C (en) * | 2013-03-14 | 2021-09-21 | Deuterx, Llc | Deuterium-enriched 2,4-thiazolidinediones and methods of treatment |
EP3094328B1 (en) | 2014-01-15 | 2020-08-19 | Poxel SA | Methods of treating neurological, metabolic, and other disorders using enantiopure deuterium-enriched pioglitazone |
SI3388064T1 (sl) * | 2014-04-02 | 2021-08-31 | Minoryx Therapeutics S.L. | Derivati 2,4-tiazolidindiona pri zdravljenju motenj centralnega živčnega sistema |
US10034868B2 (en) | 2014-11-04 | 2018-07-31 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for the prevention and the treatment of rapidly progressive glomerulonephritis |
WO2018100557A1 (en) | 2016-12-01 | 2018-06-07 | Minoryx Therapeutics S.L. | 5-[[4-[2-[5-(1-hydroxyethyl)pyridin-2-yl]ethoxy]phenyl]methyl]-1,3-thiazolidine- 2,4-dione for treating nonalcoholic fatty liver disease |
PL3559010T3 (pl) | 2016-12-23 | 2022-11-21 | Minoryx Therapeutics S.L. | Sposób wytwarzania 5-[[4-[2-[5-(1-hydroksyetylo)-2-pirydynylo]etoksy]fenylo]metylo]-2,4-tiazolidynodionu i jego soli |
US11319313B2 (en) | 2020-06-30 | 2022-05-03 | Poxel Sa | Crystalline forms of deuterium-enriched pioglitazone |
US11767317B1 (en) | 2020-06-30 | 2023-09-26 | Poxel Sa | Methods of synthesizing enantiopure deuterium-enriched pioglitazone |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5522636A (en) * | 1978-08-04 | 1980-02-18 | Takeda Chem Ind Ltd | Thiazoliding derivative |
AR240698A1 (es) * | 1985-01-19 | 1990-09-28 | Takeda Chemical Industries Ltd | Procedimiento para preparar compuestos de 5-(4-(2-(5-etil-2-piridil)-etoxi)benzil)-2,4-tiazolidindiona y sus sales |
-
1992
- 1992-04-06 AU AU17432/92A patent/AU1743292A/en not_active Abandoned
- 1992-04-06 DK DK92910028T patent/DK0579733T3/da active
- 1992-04-06 CA CA002106967A patent/CA2106967C/en not_active Expired - Lifetime
- 1992-04-06 ES ES92910028T patent/ES2161692T3/es not_active Expired - Lifetime
- 1992-04-06 WO PCT/US1992/002566 patent/WO1992018501A1/en active IP Right Grant
- 1992-04-06 CZ CS931966A patent/CZ196693A3/cs unknown
- 1992-04-06 DE DE69231886T patent/DE69231886T2/de not_active Expired - Lifetime
- 1992-04-06 AT AT92910028T patent/ATE202352T1/de active
- 1992-04-06 SK SK1099-93A patent/SK109993A3/sk unknown
- 1992-04-06 HU HU9302859A patent/HUT68370A/hu unknown
- 1992-04-06 EP EP92910028A patent/EP0579733B1/en not_active Expired - Lifetime
- 1992-04-06 KR KR1019930703064A patent/KR100249988B1/ko not_active IP Right Cessation
- 1992-04-07 JP JP08540592A patent/JP3176694B2/ja not_active Expired - Lifetime
- 1992-04-09 MX MX9201637A patent/MX9201637A/es unknown
- 1992-04-09 PT PT100366A patent/PT100366A/pt not_active Application Discontinuation
- 1992-04-11 TW TW081102843A patent/TW209864B/zh active
-
1993
- 1993-10-08 FI FI934426A patent/FI934426A0/fi not_active Application Discontinuation
- 1993-10-08 NO NO933615A patent/NO933615L/no unknown
-
2001
- 2001-09-17 GR GR20010401481T patent/GR3036623T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
TW209864B (ko) | 1993-07-21 |
KR100249988B1 (ko) | 2000-04-01 |
NO933615D0 (no) | 1993-10-08 |
DE69231886D1 (de) | 2001-07-26 |
MX9201637A (es) | 1993-08-01 |
DE69231886T2 (de) | 2002-03-28 |
JP3176694B2 (ja) | 2001-06-18 |
GR3036623T3 (en) | 2001-12-31 |
SK109993A3 (en) | 1994-12-07 |
PT100366A (pt) | 1993-06-30 |
HUT68370A (en) | 1995-06-28 |
CA2106967C (en) | 2003-12-09 |
WO1992018501A1 (en) | 1992-10-29 |
FI934426A (fi) | 1993-10-08 |
JPH0586057A (ja) | 1993-04-06 |
DK0579733T3 (da) | 2001-10-15 |
EP0579733B1 (en) | 2001-06-20 |
CZ196693A3 (en) | 1994-05-18 |
AU1743292A (en) | 1992-11-17 |
CA2106967A1 (en) | 1992-10-12 |
EP0579733A1 (en) | 1994-01-26 |
ATE202352T1 (de) | 2001-07-15 |
ES2161692T3 (es) | 2001-12-16 |
FI934426A0 (fi) | 1993-10-08 |
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