DK0579733T3 - Thiazolidindionderivater, fremstilling og anvendelse deraf - Google Patents

Thiazolidindionderivater, fremstilling og anvendelse deraf

Info

Publication number
DK0579733T3
DK0579733T3 DK92910028T DK92910028T DK0579733T3 DK 0579733 T3 DK0579733 T3 DK 0579733T3 DK 92910028 T DK92910028 T DK 92910028T DK 92910028 T DK92910028 T DK 92910028T DK 0579733 T3 DK0579733 T3 DK 0579733T3
Authority
DK
Denmark
Prior art keywords
preparation
thiazolidinedione derivatives
general formula
thiazolidinedione derivative
thiazolidinedione
Prior art date
Application number
DK92910028T
Other languages
English (en)
Inventor
Takashi Sohda
Hitoshi Ikeda
John C Greenfield
Jerry R Colca
Edgar N Petzold
Original Assignee
Upjohn Co
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=13672917&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0579733(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Upjohn Co, Takeda Chemical Industries Ltd filed Critical Upjohn Co
Application granted granted Critical
Publication of DK0579733T3 publication Critical patent/DK0579733T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
DK92910028T 1991-04-11 1992-04-06 Thiazolidindionderivater, fremstilling og anvendelse deraf DK0579733T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP7883691 1991-04-11
PCT/US1992/002566 WO1992018501A1 (en) 1991-04-11 1992-04-06 Thiazolidinedione derivatives, production and use thereof

Publications (1)

Publication Number Publication Date
DK0579733T3 true DK0579733T3 (da) 2001-10-15

Family

ID=13672917

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92910028T DK0579733T3 (da) 1991-04-11 1992-04-06 Thiazolidindionderivater, fremstilling og anvendelse deraf

Country Status (19)

Country Link
EP (1) EP0579733B1 (da)
JP (1) JP3176694B2 (da)
KR (1) KR100249988B1 (da)
AT (1) ATE202352T1 (da)
AU (1) AU1743292A (da)
CA (1) CA2106967C (da)
CZ (1) CZ196693A3 (da)
DE (1) DE69231886T2 (da)
DK (1) DK0579733T3 (da)
ES (1) ES2161692T3 (da)
FI (1) FI934426A (da)
GR (1) GR3036623T3 (da)
HU (1) HUT68370A (da)
MX (1) MX9201637A (da)
NO (1) NO933615D0 (da)
PT (1) PT100366A (da)
SK (1) SK109993A3 (da)
TW (1) TW209864B (da)
WO (1) WO1992018501A1 (da)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993022445A1 (en) * 1992-05-05 1993-11-11 The Upjohn Company A process for producing pioglitazone metabolite
TW268952B (da) * 1993-02-26 1996-01-21 Takeda Pharm Industry Co Ltd
CA2146701A1 (en) * 1994-04-11 1995-10-12 Takashi Fujita Heterocyclic compounds having anti-diabetic activity, their preparation and their use
US5952509A (en) * 1996-06-27 1999-09-14 Takeda Chemical Industries, Ltd. Production of benzaldehyde compounds
TR199903096T2 (xx) 1997-06-18 2000-08-21 Smithkline Beecham P.L.C. Diabetin tiazolidinedion ve s�lfonil�re ile tedavisi.
SI1131070T1 (sl) * 1998-11-12 2008-12-31 Smithkline Beecham Plc Farmacevtski sestavek za modificirano sproĺ äśanje senzibilizatorja za inzulin in metformina
DZ2937A1 (fr) 1998-11-12 2004-03-15 Smithkline Beecham Plc Compositions nouvelles de sensibilidants à l'insuline.
GB0014969D0 (en) 2000-06-19 2000-08-09 Smithkline Beecham Plc Novel method of treatment
DE20119200U1 (de) 2001-11-27 2003-04-10 Winklhofer & Soehne Gmbh Kettenspanner mit mechanischer Verriegelung
US8268352B2 (en) 2002-08-05 2012-09-18 Torrent Pharmaceuticals Limited Modified release composition for highly soluble drugs
US8216609B2 (en) 2002-08-05 2012-07-10 Torrent Pharmaceuticals Limited Modified release composition of highly soluble drugs
KR100646128B1 (ko) 2005-04-21 2006-11-14 전라옥 ＰＰＡＲγ에 선택적으로 작용하는 테트라하이드로퀴놀린계열 티아졸리딘디온 유도체 및 그 합성방법
AU2013200104B2 (en) * 2006-03-16 2014-05-15 Metabolic Solutions Development Company, Llc Thiazolidinedione analogues for the treatment of metabolic inflammation mediated disease
AU2007227552A1 (en) * 2006-03-16 2007-09-27 Metabolic Solutions Development Company Combination therapies of thiazolidinedione analogues and glucocorticoid agonists
CA2646149A1 (en) * 2006-03-16 2007-09-27 Metabolic Solutions Development Company Thiazolidinedione analogues for the treatment of hypertension and for lowering lipids
HUE035314T2 (en) * 2006-03-16 2018-05-02 Metabolic Solutions Dev Co Llc Thiazolidinedione analogues for the treatment of a disease mediated by metabolic inflammation
US7435741B2 (en) 2006-05-09 2008-10-14 Teva Pharmaceutical Industries, Ltd. 2-N{5-[[4-[2-(methyl-2-pyridinylamino) ethoxy] phenyl]methyl]-2,4-thiazolidinedione} butanedioic acid, methods of preparation and compositions with rosiglitazone maleate
WO2008038359A1 (fr) 2006-09-28 2008-04-03 Daido Kogyo Co., Ltd. Tensionneur de chaîne
WO2009038681A1 (en) 2007-09-14 2009-03-26 Metabolic Solutions Development Company Thiazolidinedione analogues for the treatment of hypertension
US8304441B2 (en) 2007-09-14 2012-11-06 Metabolic Solutions Development Company, Llc Thiazolidinedione analogues for the treatment of metabolic diseases
US8722710B2 (en) 2007-09-26 2014-05-13 Deuterx, Llc Deuterium-enriched pioglitazone
NO2513070T3 (da) 2009-12-15 2018-04-07
MX2012012094A (es) * 2010-04-19 2012-12-17 Metabolic Solutions Dev Co Llc Sintesis novedosa para compuestos de tiazolidinadiona.
ES2610623T3 (es) * 2010-04-19 2017-04-28 Octeta Therapeutics, Llc Nueva síntesis de compuestos de tiazolidindiona
KR20130099034A (ko) 2010-08-10 2013-09-05 메타볼릭 솔루션스 디벨롭먼트 컴퍼니, 엘엘씨 티아졸리딘디온 화합물의 신규한 합성법
MX342289B (es) * 2010-08-10 2016-09-23 Metabolic Solutions Dev Company Llc * Sintesis para compuestos de tiazolidindiona.
US20120094959A1 (en) 2010-10-19 2012-04-19 Bonnie Blazer-Yost Treatment of cystic diseases
WO2014152843A1 (en) * 2013-03-14 2014-09-25 Deuterx, Llc Deuterium-enriched 2,4-thiazolidinediones and methods of treatment
WO2015109037A1 (en) 2014-01-15 2015-07-23 Deuterx, Llc Methods of treating neurological, metabolic, and other disorders using enantiopure deuterium-enriched pioglitazone
EA202091120A3 (ru) * 2014-04-02 2020-12-30 Минорикс Терапьютикс С.Л. Производные 2,4-тиазолинидона в лечении расстройств центральной нервной системы
US10034868B2 (en) 2014-11-04 2018-07-31 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for the prevention and the treatment of rapidly progressive glomerulonephritis
JP7040798B2 (ja) 2016-12-01 2022-03-23 ミノリックス セラピューティクス エセ．エレ． 非アルコール性脂肪性肝疾患を処置するための５－［［４－［２－［５－（１－ヒドロキシエチル）ピリジン－２－イル］エトキシ］フェニル］メチル］－１，３－チアゾリジン－２，４－ジオン
CN110198945B (zh) * 2016-12-23 2023-06-27 米尼奥尔克斯治疗有限公司 用于制备噻唑烷二酮化合物及其盐的方法
US11767317B1 (en) 2020-06-30 2023-09-26 Poxel Sa Methods of synthesizing enantiopure deuterium-enriched pioglitazone
US11319313B2 (en) 2020-06-30 2022-05-03 Poxel Sa Crystalline forms of deuterium-enriched pioglitazone

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5522636A (en) * 1978-08-04 1980-02-18 Takeda Chem Ind Ltd Thiazoliding derivative
AR240698A1 (es) * 1985-01-19 1990-09-28 Takeda Chemical Industries Ltd Procedimiento para preparar compuestos de 5-(4-(2-(5-etil-2-piridil)-etoxi)benzil)-2,4-tiazolidindiona y sus sales

Also Published As

Publication number Publication date
FI934426A0 (fi) 1993-10-08
CA2106967A1 (en) 1992-10-12
CA2106967C (en) 2003-12-09
TW209864B (da) 1993-07-21
SK109993A3 (en) 1994-12-07
DE69231886D1 (de) 2001-07-26
CZ196693A3 (en) 1994-05-18
JP3176694B2 (ja) 2001-06-18
PT100366A (pt) 1993-06-30
DE69231886T2 (de) 2002-03-28
NO933615L (no) 1993-10-08
GR3036623T3 (en) 2001-12-31
FI934426A (fi) 1993-10-08
MX9201637A (es) 1993-08-01
WO1992018501A1 (en) 1992-10-29
NO933615D0 (no) 1993-10-08
EP0579733A1 (en) 1994-01-26
ATE202352T1 (de) 2001-07-15
HUT68370A (en) 1995-06-28
KR100249988B1 (ko) 2000-04-01
JPH0586057A (ja) 1993-04-06
ES2161692T3 (es) 2001-12-16
AU1743292A (en) 1992-11-17
EP0579733B1 (en) 2001-06-20

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