NO910304L - Nye leukotrien-b4-derivater, fremgangsmaate for deres fremstilling og deres anvendelse som legemiddel. - Google Patents
Nye leukotrien-b4-derivater, fremgangsmaate for deres fremstilling og deres anvendelse som legemiddel.Info
- Publication number
- NO910304L NO910304L NO91910304A NO910304A NO910304L NO 910304 L NO910304 L NO 910304L NO 91910304 A NO91910304 A NO 91910304A NO 910304 A NO910304 A NO 910304A NO 910304 L NO910304 L NO 910304L
- Authority
- NO
- Norway
- Prior art keywords
- image
- pct
- group
- leukotrien
- medicine
- Prior art date
Links
- 238000000034 method Methods 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000000008 (C1-C10) alkyl group Chemical group 0.000 abstract 1
- 229920000858 Cyclodextrin Polymers 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 239000005864 Sulphur Substances 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- CBOIHMRHGLHBPB-UHFFFAOYSA-N hydroxymethyl Chemical group O[CH2] CBOIHMRHGLHBPB-UHFFFAOYSA-N 0.000 abstract 1
- 150000007524 organic acids Chemical group 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical compound O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 abstract 1
- 125000000383 tetramethylene group Chemical group [H]C([H])([*:1])C([H])([H])C([H])([H])C([H])([H])[*:2] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
- C07C403/06—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms
- C07C403/12—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms by esterified hydroxy groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
- C07C33/05—Alcohols containing rings other than six-membered aromatic rings
- C07C33/14—Alcohols containing rings other than six-membered aromatic rings containing six-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
- C07C403/06—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms
- C07C403/08—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms by hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/005—Analogues or derivatives having the five membered ring replaced by other rings
- C07C405/0058—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a not condensed ring different from a five-membered ring
- C07C405/0066—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a not condensed ring different from a five-membered ring to a six-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
- C07C59/46—Unsaturated compounds containing hydroxy or O-metal groups containing rings other than six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
- C07C59/48—Unsaturated compounds containing hydroxy or O-metal groups containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Steroid Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3917597A DE3917597A1 (de) | 1989-05-26 | 1989-05-26 | Neue leukotrien-b(pfeil abwaerts)4(pfeil abwaerts)-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| PCT/DE1990/000397 WO1990014329A1 (de) | 1989-05-26 | 1990-05-25 | Neue leukotrien-b4-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO910304D0 NO910304D0 (no) | 1991-01-25 |
| NO910304L true NO910304L (no) | 1991-03-22 |
Family
ID=6381687
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO91910304A NO910304L (no) | 1989-05-26 | 1991-01-25 | Nye leukotrien-b4-derivater, fremgangsmaate for deres fremstilling og deres anvendelse som legemiddel. |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US5187286A (no) |
| EP (1) | EP0399633B1 (no) |
| JP (1) | JP2921600B2 (no) |
| AT (1) | ATE114633T1 (no) |
| AU (1) | AU5669990A (no) |
| CA (1) | CA2033187A1 (no) |
| DD (1) | DD294705A5 (no) |
| DE (2) | DE3917597A1 (no) |
| DK (1) | DK0399633T3 (no) |
| ES (1) | ES2065475T3 (no) |
| FI (1) | FI910346A0 (no) |
| GR (1) | GR3015097T3 (no) |
| HU (1) | HUT55745A (no) |
| NO (1) | NO910304L (no) |
| WO (1) | WO1990014329A1 (no) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5414016A (en) * | 1991-03-12 | 1995-05-09 | Schering Aktiengesellschaft | New leukotriene-B4 derivatives, process for their production and their use as pharmaceutical agents |
| DE4108351A1 (de) * | 1991-03-12 | 1992-09-17 | Schering Ag | Neue leukotrien-b(pfeil abwaerts)4(pfeil abwaerts)-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| AU656027B2 (en) * | 1991-11-15 | 1995-01-19 | Sanofi | Saccharin derivative proteolytic enzime inhibitors |
| WO1993011105A1 (de) * | 1991-11-29 | 1993-06-10 | Schering Aktiengesellschaft | Leukotrien-b4-derivative, verfahren zu ihrer herstellung und arzneimittel |
| ES2118379T3 (es) * | 1994-01-27 | 1998-09-16 | Schering Ag | Nuevos derivados de leucotrieno b4, procedimiento para su preparacion y su utilizacion como medicamentos. |
| AU5971394A (en) * | 1994-01-27 | 1995-08-15 | Schering Aktiengesellschaft | Leukotriene b4 derivatives, methods of preparing them and their use as drugs |
| CN1049992C (zh) * | 1994-09-16 | 2000-03-01 | 联华电子股份有限公司 | 用于图像合成装置的位置转换装置 |
| DE19722853A1 (de) * | 1997-05-23 | 1998-12-10 | Schering Ag | Leukotrien-B¶4¶-Antagonisten, insbesondere 3-Carba-Tetrahydronaphthalin-LTB¶4¶-Antagonisten |
| DE19722846A1 (de) * | 1997-05-23 | 1998-12-24 | Schering Ag | Leukotrien-B¶4¶-Derivate, insbesondere 7-Methylcyclohexyl-LTB¶4¶-Antagonisten |
| DE19722845A1 (de) * | 1997-05-23 | 1998-12-10 | Schering Ag | Leukotrien-B¶4¶-Derivate, insbesondere Interphenylen-7-Methylcyclohexyl-LTB¶4¶-Antagonisten |
| US8729108B2 (en) * | 2008-06-17 | 2014-05-20 | Christopher J Dannaker | Waterborne topical compositions for the delivery of active ingredients such as azelaic acid |
| WO2010039531A1 (en) * | 2008-09-23 | 2010-04-08 | Resolvyx Pharmaceuticals, Inc. | Therapeutic compounds |
-
1989
- 1989-05-26 DE DE3917597A patent/DE3917597A1/de not_active Withdrawn
-
1990
- 1990-05-25 AU AU56699/90A patent/AU5669990A/en not_active Abandoned
- 1990-05-25 AT AT90250136T patent/ATE114633T1/de not_active IP Right Cessation
- 1990-05-25 CA CA002033187A patent/CA2033187A1/en not_active Abandoned
- 1990-05-25 DE DE59007805T patent/DE59007805D1/de not_active Expired - Lifetime
- 1990-05-25 WO PCT/DE1990/000397 patent/WO1990014329A1/de active Application Filing
- 1990-05-25 EP EP90250136A patent/EP0399633B1/de not_active Expired - Lifetime
- 1990-05-25 HU HU905269A patent/HUT55745A/hu unknown
- 1990-05-25 ES ES90250136T patent/ES2065475T3/es not_active Expired - Lifetime
- 1990-05-25 DK DK90250136.0T patent/DK0399633T3/da active
- 1990-05-25 US US07/663,927 patent/US5187286A/en not_active Expired - Fee Related
- 1990-05-25 JP JP2507895A patent/JP2921600B2/ja not_active Expired - Lifetime
- 1990-05-28 DD DD90341066A patent/DD294705A5/de not_active IP Right Cessation
-
1991
- 1991-01-23 FI FI910346A patent/FI910346A0/fi not_active Application Discontinuation
- 1991-01-25 NO NO91910304A patent/NO910304L/no unknown
-
1995
- 1995-02-17 GR GR940404144T patent/GR3015097T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HUT55745A (en) | 1991-06-28 |
| HU905269D0 (en) | 1991-05-28 |
| WO1990014329A1 (de) | 1990-11-29 |
| DD294705A5 (de) | 1991-10-10 |
| JPH04501119A (ja) | 1992-02-27 |
| JP2921600B2 (ja) | 1999-07-19 |
| GR3015097T3 (en) | 1995-05-31 |
| US5187286A (en) | 1993-02-16 |
| DE59007805D1 (de) | 1995-01-12 |
| NO910304D0 (no) | 1991-01-25 |
| ATE114633T1 (de) | 1994-12-15 |
| DK0399633T3 (da) | 1995-05-15 |
| EP0399633A1 (de) | 1990-11-28 |
| FI910346A0 (fi) | 1991-01-23 |
| CA2033187A1 (en) | 1990-11-27 |
| EP0399633B1 (de) | 1994-11-30 |
| ES2065475T3 (es) | 1995-02-16 |
| AU5669990A (en) | 1990-12-18 |
| DE3917597A1 (de) | 1990-11-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO910304L (no) | Nye leukotrien-b4-derivater, fremgangsmaate for deres fremstilling og deres anvendelse som legemiddel. | |
| KR900001684A (ko) | (1-히드록시-2- 피페리딜알킬)-인돌-2-온, 2-퀴놀리논, 2- 벤조[b] 아자피논, 벤즈이미다졸-2-온 및 퀴나졸린-2-온의 유도체, 그의 제조 및 치료요법에서의 그의 적용 | |
| DE3271269D1 (en) | Benzimidazole derivatives, process for the preparation thereof and pharmaceutical composition containing the same | |
| KR890005086A (ko) | 1-[(2- 피리미디닐) 아미노알킬]피페리딘, 그의 제법 및 치료에의 이용 | |
| DK118083D0 (da) | Theophyllinylalkyloxadiazoler eller additionssalte deraf, deres fremstilling og anvendelse som laegemidler | |
| DE3170937D1 (en) | 2-(1,4-benzodioxan-2-ylalkyl) imidazoles, their preparation and pharmaceutical compositions containing them | |
| KR880003941A (ko) | 4,5-디하이드로옥사졸 유도체, 그의 제조방법 및 용도 | |
| ES2056137T3 (es) | Nuevas alcanofenonas. | |
| DK0419610T3 (da) | Leukotrien-B4-derivater og fremgangsmåde til fremstilling deraf | |
| MX9204457A (es) | Compuestos de 6-oxo-azepinoidol, asi como procedimientos y productos intermedios para su preparacion, y medicamentos que contienen estos compuestos. | |
| SE7909367L (sv) | Sett att framstella piperidyl-indol-derivat, ny framstelld forening och dess salter samt anvendning derav sasom lekemedel och farmaceutiska kompositioner innehallande dessa foreningar | |
| AU658175B2 (en) | Use of 2-iminothiazolidin-4-one derivatives as novel pharmaceutical active ingredients | |
| ZA84261B (en) | Bicyclo(4.2.0)1,3,5-octatriene derivatives,a process for their preparation and pharmaceutical compositions containing them | |
| PT76335B (de) | Neue basisch substituierte 4-phenyl-4,5,6,7-tetrahydro-thieno-<2,3-c>pyridine verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen | |
| HU895522D0 (en) | Process for the preparation of new thienyl-oxy-alkyl-amine derivatives and pharmaceutical compositions containing them | |
| RU1771475C (ru) | Способ получени 6-бензилоксизамещенных изопропиловых эфиров @ -карболин-3-карбоновой кислоты | |
| DK0416069T3 (da) | Leukotrien-B4derivater og fremgangsmåde til fremstilling deraf | |
| SE8005493L (sv) | 4-(haftalenyloxi)piperidin-derivat | |
| FI925618A (fi) | Etanoladdukter av 6-sulfonylsubstituerade 3-hydroxikromaner och deras anvaendning som inhalationsmedel vid sjukdomar | |
| FI860098A0 (fi) | Nya piperazinderivat, foerfarande foer deras framstaellning och farmaceutiska kompositioner som innehaoller dessa foereningar som aktiv ingrediens. | |
| SE8207294D0 (sv) | 1,4-tiazankarboxylsyraderivat, deras framstellning och anvendning och kompositioner vari dessa derivat ingar | |
| SE8400629D0 (sv) | Novel basic oxime ethers and a process for preparing same | |
| ES391916A1 (es) | Un procedimiento de preparar nuevos compuestos de sulfoni- lurea o de sus sales. | |
| ES8203876A1 (es) | Procedimiento de obtencion de nuevos a-amino derivados ci- clicos del 1-(3',4'-metilendioxifenil)etanol | |
| DE69016378D1 (de) | Substituierte Benzothiazolinone, ihre Herstellung und sie enthaltende pharmazeutische Zusammenstellungen. |