NO910304L - Nye leukotrien-b4-derivater, fremgangsmaate for deres fremstilling og deres anvendelse som legemiddel. - Google Patents

Nye leukotrien-b4-derivater, fremgangsmaate for deres fremstilling og deres anvendelse som legemiddel.

Info

Publication number
NO910304L
NO910304L NO91910304A NO910304A NO910304L NO 910304 L NO910304 L NO 910304L NO 91910304 A NO91910304 A NO 91910304A NO 910304 A NO910304 A NO 910304A NO 910304 L NO910304 L NO 910304L
Authority
NO
Norway
Prior art keywords
image
pct
group
leukotrien
medicine
Prior art date
Application number
NO91910304A
Other languages
English (en)
Other versions
NO910304D0 (no
Inventor
Werner Skuballa
Bernd Buchmann
Joseph Heindl
Wolfgang Froehlich
Roland Ekerdt
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of NO910304D0 publication Critical patent/NO910304D0/no
Publication of NO910304L publication Critical patent/NO910304L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/06Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms
    • C07C403/12Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms by esterified hydroxy groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/05Alcohols containing rings other than six-membered aromatic rings
    • C07C33/14Alcohols containing rings other than six-membered aromatic rings containing six-membered rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/06Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms
    • C07C403/08Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms by hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/005Analogues or derivatives having the five membered ring replaced by other rings
    • C07C405/0058Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a not condensed ring different from a five-membered ring
    • C07C405/0066Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a not condensed ring different from a five-membered ring to a six-membered ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/42Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/46Unsaturated compounds containing hydroxy or O-metal groups containing rings other than six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/42Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/48Unsaturated compounds containing hydroxy or O-metal groups containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrrole Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO91910304A 1989-05-26 1991-01-25 Nye leukotrien-b4-derivater, fremgangsmaate for deres fremstilling og deres anvendelse som legemiddel. NO910304L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3917597A DE3917597A1 (de) 1989-05-26 1989-05-26 Neue leukotrien-b(pfeil abwaerts)4(pfeil abwaerts)-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
PCT/DE1990/000397 WO1990014329A1 (de) 1989-05-26 1990-05-25 Neue leukotrien-b4-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Publications (2)

Publication Number Publication Date
NO910304D0 NO910304D0 (no) 1991-01-25
NO910304L true NO910304L (no) 1991-03-22

Family

ID=6381687

Family Applications (1)

Application Number Title Priority Date Filing Date
NO91910304A NO910304L (no) 1989-05-26 1991-01-25 Nye leukotrien-b4-derivater, fremgangsmaate for deres fremstilling og deres anvendelse som legemiddel.

Country Status (15)

Country Link
US (1) US5187286A (no)
EP (1) EP0399633B1 (no)
JP (1) JP2921600B2 (no)
AT (1) ATE114633T1 (no)
AU (1) AU5669990A (no)
CA (1) CA2033187A1 (no)
DD (1) DD294705A5 (no)
DE (2) DE3917597A1 (no)
DK (1) DK0399633T3 (no)
ES (1) ES2065475T3 (no)
FI (1) FI910346A0 (no)
GR (1) GR3015097T3 (no)
HU (1) HUT55745A (no)
NO (1) NO910304L (no)
WO (1) WO1990014329A1 (no)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5414016A (en) * 1991-03-12 1995-05-09 Schering Aktiengesellschaft New leukotriene-B4 derivatives, process for their production and their use as pharmaceutical agents
DE4108351A1 (de) * 1991-03-12 1992-09-17 Schering Ag Neue leukotrien-b(pfeil abwaerts)4(pfeil abwaerts)-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
AU656027B2 (en) * 1991-11-15 1995-01-19 Sanofi Saccharin derivative proteolytic enzime inhibitors
DK0614457T3 (no) * 1991-11-29 1997-02-24 Schering Ag
ES2118379T3 (es) * 1994-01-27 1998-09-16 Schering Ag Nuevos derivados de leucotrieno b4, procedimiento para su preparacion y su utilizacion como medicamentos.
AU5971394A (en) * 1994-01-27 1995-08-15 Schering Aktiengesellschaft Leukotriene b4 derivatives, methods of preparing them and their use as drugs
CN1049992C (zh) * 1994-09-16 2000-03-01 联华电子股份有限公司 用于图像合成装置的位置转换装置
DE19722853A1 (de) * 1997-05-23 1998-12-10 Schering Ag Leukotrien-B¶4¶-Antagonisten, insbesondere 3-Carba-Tetrahydronaphthalin-LTB¶4¶-Antagonisten
DE19722846A1 (de) * 1997-05-23 1998-12-24 Schering Ag Leukotrien-B¶4¶-Derivate, insbesondere 7-Methylcyclohexyl-LTB¶4¶-Antagonisten
DE19722845A1 (de) * 1997-05-23 1998-12-10 Schering Ag Leukotrien-B¶4¶-Derivate, insbesondere Interphenylen-7-Methylcyclohexyl-LTB¶4¶-Antagonisten
US8729108B2 (en) * 2008-06-17 2014-05-20 Christopher J Dannaker Waterborne topical compositions for the delivery of active ingredients such as azelaic acid
WO2010039531A1 (en) * 2008-09-23 2010-04-08 Resolvyx Pharmaceuticals, Inc. Therapeutic compounds

Also Published As

Publication number Publication date
FI910346A0 (fi) 1991-01-23
GR3015097T3 (en) 1995-05-31
AU5669990A (en) 1990-12-18
HU905269D0 (en) 1991-05-28
WO1990014329A1 (de) 1990-11-29
DK0399633T3 (da) 1995-05-15
ATE114633T1 (de) 1994-12-15
ES2065475T3 (es) 1995-02-16
NO910304D0 (no) 1991-01-25
JPH04501119A (ja) 1992-02-27
DE3917597A1 (de) 1990-11-29
US5187286A (en) 1993-02-16
EP0399633B1 (de) 1994-11-30
DE59007805D1 (de) 1995-01-12
EP0399633A1 (de) 1990-11-28
JP2921600B2 (ja) 1999-07-19
HUT55745A (en) 1991-06-28
CA2033187A1 (en) 1990-11-27
DD294705A5 (de) 1991-10-10

Similar Documents

Publication Publication Date Title
NO910304D0 (no) Nye leukotrien-b4-derivater, fremgangsmaate for deres fremstilling og deres anvendelse som legemiddel.
KR900001684A (ko) (1-히드록시-2- 피페리딜알킬)-인돌-2-온, 2-퀴놀리논, 2- 벤조[b] 아자피논, 벤즈이미다졸-2-온 및 퀴나졸린-2-온의 유도체, 그의 제조 및 치료요법에서의 그의 적용
ATE31411T1 (de) Piperazin-derivate, verfahren zu ihrer herstellung und diese als aktive bestandteile enthaltende pharmazeutische zusammensetzungen.
DE3271269D1 (en) Benzimidazole derivatives, process for the preparation thereof and pharmaceutical composition containing the same
NO940523L (no) Nye pyrazin-derivater
SE8700714L (sv) Anvendning av substituerade 4-fenyl-4-oxo-2-butensyraderivat for framstellning av lekemedel for behandling av sjukdomar i matsmeltningskanalen och som antiulcerost lekemedel
DE3170937D1 (en) 2-(1,4-benzodioxan-2-ylalkyl) imidazoles, their preparation and pharmaceutical compositions containing them
KR880003941A (ko) 4,5-디하이드로옥사졸 유도체, 그의 제조방법 및 용도
ES2056137T3 (es) Nuevas alcanofenonas.
ES2060150T3 (es) Nuevos derivados de leucotrieno-b4, procedimiento para su preparacion y su utilizacion como medicamentos.
SE8300855L (sv) Nya piperazin- och homopiperazinderivat, forfaranden for framstellning derav och farmaceutiska kompositioner innehallande dem
MX9204457A (es) Compuestos de 6-oxo-azepinoidol, asi como procedimientos y productos intermedios para su preparacion, y medicamentos que contienen estos compuestos.
SE7909367L (sv) Sett att framstella piperidyl-indol-derivat, ny framstelld forening och dess salter samt anvendning derav sasom lekemedel och farmaceutiska kompositioner innehallande dessa foreningar
AU658175B2 (en) Use of 2-iminothiazolidin-4-one derivatives as novel pharmaceutical active ingredients
HU895522D0 (en) Process for the preparation of new thienyl-oxy-alkyl-amine derivatives and pharmaceutical compositions containing them
RU1771475C (ru) Способ получени 6-бензилоксизамещенных изопропиловых эфиров @ -карболин-3-карбоновой кислоты
DK0416069T3 (da) Leukotrien-B4derivater og fremgangsmåde til fremstilling deraf
SE8005493L (sv) 4-(haftalenyloxi)piperidin-derivat
FI925618A (fi) Etanoladdukter av 6-sulfonylsubstituerade 3-hydroxikromaner och deras anvaendning som inhalationsmedel vid sjukdomar
FI860098A (fi) Nya piperazinderivat, foerfarande foer deras framstaellning och farmaceutiska kompositioner som innehaoller dessa foereningar som aktiv ingrediens.
ES2062793T3 (es) Procedimiento para la preparacion de derivados 7alfa-alcoxicefemes.
SE8207294D0 (sv) 1,4-tiazankarboxylsyraderivat, deras framstellning och anvendning och kompositioner vari dessa derivat ingar
SE8400629D0 (sv) Novel basic oxime ethers and a process for preparing same
ES391916A1 (es) Un procedimiento de preparar nuevos compuestos de sulfoni- lurea o de sus sales.
SE8104508L (sv) Ergolinderivat, sett att framstella dessa, farmaceutiska kompositioner innehallande desamma och anvendning derav vid terapeutisk behandling