NO904854D0 - 19-nor-vitamin d-forbindelser. - Google Patents

19-nor-vitamin d-forbindelser.

Info

Publication number
NO904854D0
NO904854D0 NO904854A NO904854A NO904854D0 NO 904854 D0 NO904854 D0 NO 904854D0 NO 904854 A NO904854 A NO 904854A NO 904854 A NO904854 A NO 904854A NO 904854 D0 NO904854 D0 NO 904854D0
Authority
NO
Norway
Prior art keywords
vitamin
compounds
Prior art date
Application number
NO904854A
Other languages
English (en)
Other versions
NO904854L (no
Inventor
Hector F Deluca
Heinrich K Schnoes
Kato L Perlman
Rafal R Sicinski
Jean Martin Prahl
Original Assignee
Wisconsin Alumni Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23248877&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO904854(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found
Publication of NO904854L publication Critical patent/NO904854L/no
Publication of NO904854D0 publication Critical patent/NO904854D0/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
    • A61P5/12—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH for decreasing, blocking or antagonising the activity of the posterior pituitary hormones
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO904854A 1989-03-09 1990-11-08 19-nor-vitamin d-forbindelser. NO904854D0 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32103089A 1989-03-09 1989-03-09
PCT/US1990/000954 WO1990010620A1 (en) 1989-03-09 1990-02-16 19-nor-vitamin d compounds

Publications (2)

Publication Number Publication Date
NO904854L NO904854L (no) 1990-11-08
NO904854D0 true NO904854D0 (no) 1990-11-08

Family

ID=23248877

Family Applications (1)

Application Number Title Priority Date Filing Date
NO904854A NO904854D0 (no) 1989-03-09 1990-11-08 19-nor-vitamin d-forbindelser.

Country Status (15)

Country Link
US (7) US5237110A (no)
JP (1) JPH0667899B2 (no)
KR (1) KR950013636B1 (no)
AR (1) AR246254A1 (no)
AU (1) AU632315B2 (no)
BR (1) BR9004521A (no)
CA (1) CA1333616C (no)
FI (1) FI905489A0 (no)
HU (2) HU222491B1 (no)
IL (1) IL93455A (no)
NO (1) NO904854D0 (no)
RO (1) RO109331B1 (no)
RU (2) RU2055068C1 (no)
WO (1) WO1990010620A1 (no)
ZA (1) ZA907119B (no)

Families Citing this family (96)

* Cited by examiner, † Cited by third party
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US5798345A (en) * 1990-09-21 1998-08-25 Bone Care International, Inc. Method of inhibiting the hyperproliferation of malignant cells
US5763428A (en) * 1990-09-21 1998-06-09 Bone Care International, Inc. Methods of treating skin disorders with novel 1a-hydroxy vitamin D4 compounds and derivatives thereof
DE69132862T2 (de) * 1990-09-21 2002-08-29 Bone Care International Inc., Madison Neues 1alpha-hydroxy vitamin-d4 und neue zwischenprodukte und analoge
US5182396A (en) * 1991-03-29 1993-01-26 Nisshin Flour Milling Co., Ltd. 1-hydroxyvitamin d derivatives
DE69213844T2 (de) * 1991-07-05 1997-04-10 Duphar Int Res Vitamin-D Derivat, Verfahren zu dessen Herstellung sowie Zwischenprodukte dafür
DE4220757A1 (de) * 1992-06-24 1994-01-05 Schering Ag Derivate in der Vitamin D-Reihe mit Modifikationen in der 20-Position, Verfahren zu ihrer Herstellung, Zwischenprodukte für dieses Verfahren, diese Derivate enthaltende pharmazeutische Präparate sowie deren Verwendung zur Herstellung von Arzneimitteln
AU666563B2 (en) * 1992-08-07 1996-02-15 Wisconsin Alumni Research Foundation Preparation of 19-nor-vitamin D compounds
TW267161B (no) * 1992-11-20 1996-01-01 Hoffmann La Roche
DE69400495T2 (de) * 1993-04-05 1997-04-30 Wisconsin Alumni Res Found 19-Nor-vitamin-D3-Verbindung mit einem Substituent an die 2. Stelle
EP0972762B1 (en) * 1993-07-09 2003-10-01 Laboratoire Theramex Novel structural analogues of vitamin D
US5763429A (en) 1993-09-10 1998-06-09 Bone Care International, Inc. Method of treating prostatic diseases using active vitamin D analogues
US20020183288A1 (en) * 1995-04-03 2002-12-05 Bone Care International, Inc. Method for treating and preventing hyperparathyroidism
US6242434B1 (en) * 1997-08-08 2001-06-05 Bone Care International, Inc. 24-hydroxyvitamin D, analogs and uses thereof
US20040043971A1 (en) * 1995-04-03 2004-03-04 Bone Care International, Inc. Method of treating and preventing hyperparathyroidism with active vitamin D analogs
US5597815A (en) * 1995-07-13 1997-01-28 Wisconsin Alumni Research Foundation Prevention of hyperphosphatemia in kidney disorder patients
US5716946A (en) * 1996-02-13 1998-02-10 Wisconsin Alumni Research Foundation Multiple sclerosis treatment
US6503893B2 (en) 1996-12-30 2003-01-07 Bone Care International, Inc. Method of treating hyperproliferative diseases using active vitamin D analogues
US6573256B2 (en) 1996-12-30 2003-06-03 Bone Care International, Inc. Method of inhibiting angiogenesis using active vitamin D analogues
US20020128240A1 (en) * 1996-12-30 2002-09-12 Bone Care International, Inc. Treatment of hyperproliferative diseases using active vitamin D analogues
US6566353B2 (en) 1996-12-30 2003-05-20 Bone Care International, Inc. Method of treating malignancy associated hypercalcemia using active vitamin D analogues
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US5945410A (en) 1997-03-17 1999-08-31 Wisconsin Alumni Research Foundation 2-alkyl-19-nor-vitamin D compounds
US6316642B1 (en) 1997-03-17 2001-11-13 Wisconsin Alumni Research Foundation 26,27-Homologated-20-EPI-2alkyl-19-nor-vitamin D compounds
US5939406A (en) * 1997-07-21 1999-08-17 Wisconsin Alumni Research Foundation 18-substituted-19-nor-vitamin D compounds
US6359152B2 (en) 1997-07-21 2002-03-19 Wisconsin Alumni Research Foundation 18-substituted-19-nor-vitamin D compounds
ES2368824T3 (es) 1998-03-27 2011-11-22 Oregon Health & Science University Vitamina d y sus análogos en el tratamiento de tumores y otros desórdenes hiperproliferativos.
US5972917A (en) * 1998-05-29 1999-10-26 Bone Care Int Inc 1 α-hydroxy-25-ene-vitamin D, analogs and uses thereof
CN1148347C (zh) 1998-05-29 2004-05-05 骨疗国际公司 羟基-25-烯-维生素d类化合物的制备方法
US5962707A (en) * 1998-08-18 1999-10-05 Wisconsin Alumni Research Foundation 19-nor-vitamin D3 compounds with calcemic activity
US6479474B2 (en) * 1999-07-08 2002-11-12 Wisconsin Alumni Research Foundation Dietary calcium as a supplement to vitamin D compound treatment of multiple sclerosis
US7122533B2 (en) * 1999-11-29 2006-10-17 The United States Of America As Represented By The Department Of Health And Human Services Cosalane compounds and methods for their use
IL152942A (en) * 2000-05-31 2007-09-20 Wisconsin Alumni Res Found Compounds 2 - Ethyl and 2 - Ethylaidine - 19 - Nur - Vitamin D and pharmaceutical preparations containing them
MXPA03000406A (es) * 2000-07-14 2003-06-06 Wisconsin Alumni Res Found Uso de 2-metilen-19-nor-20(s)-1 alfa,25-dihidroxivitamina d3 para incrementar la resistencia de los huesos.
IL153378A0 (en) * 2000-07-18 2003-07-06 Bone Care Internat Inc STABILIZED 1alpha-HYDROXY VITAMIN D
JP4022144B2 (ja) 2000-09-08 2007-12-12 ウィスコンシン・アルムニ・リサーチ・ファウンデーション １アルファ−ヒドロキシ−２−メチレン−１９−ノル−ホモプレグナカルシフェロール及びその療法的適用
JP2005504279A (ja) * 2001-09-27 2005-02-10 ザ・コカ−コーラ・カンパニー 食品のビタミン強化
US6627622B2 (en) * 2002-02-18 2003-09-30 Wisconsin Alumni Research Foundation (20S)-1α-hydroxy-2-methylene-19-nor-bishomopregnacalciferol and its uses
US6566352B1 (en) 2002-02-18 2003-05-20 Wisconsin Alumni Research Foudation 1 α-hydroxy-2-methylene-19-nor-pregnacalciferol and its uses
IL163666A0 (en) 2002-02-22 2005-12-18 New River Pharmaceuticals Inc Active agent delivery systems and methods for protecting and administering active agents
US20030195175A1 (en) * 2002-03-25 2003-10-16 Deluca Hector F. Use of carbon-2-modified-vitamin D analogs to induce the formation of new bone
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US20040053895A1 (en) * 2002-09-18 2004-03-18 Bone Care International, Inc. Multi-use vessels for vitamin D formulations
US20040058895A1 (en) * 2002-09-18 2004-03-25 Bone Care International, Inc. Multi-use vessels for vitamin D formulations
US7148211B2 (en) * 2002-09-18 2006-12-12 Genzyme Corporation Formulation for lipophilic agents
AU2004230948A1 (en) * 2003-04-10 2004-10-28 Wisconsin Alumni Research Foundation 2-propylidene-19-nor-vitamin D compounds
US6894037B2 (en) * 2003-07-03 2005-05-17 Wisconsin Alumni Research Foundation 2-methylene-19-nor-20(S)-25-methyl-1α-hydroxycalciferol and its uses
US20050009792A1 (en) * 2003-07-08 2005-01-13 Deluca Hector F. (20S)-1alpha-hydroxy-2-methylene-19-nor-vitamin D3 and its uses
US20050148557A1 (en) * 2003-07-29 2005-07-07 Jin Tian Use of Vitamin Ds to treat kidney disease
US8188064B2 (en) * 2003-11-25 2012-05-29 Wisconsin Alumni Research Foundation Vitamin D analogs for obesity prevention and treatment
US7915242B2 (en) * 2004-02-17 2011-03-29 Wisconsin Alumni Research Foundation Vitamin D receptor antagonists and their use in treating asthma
US7214671B2 (en) * 2004-02-19 2007-05-08 Wisconsin Alumni Research Foundation Use of 2-methylene-19-nor-20(S)-1α,25-dihydroxyvitamin D3 for the prophylaxis of bone diseases
US7713951B2 (en) * 2004-04-09 2010-05-11 Wisconsin Alumni Research Foundation 2-alkylidene-18,19-dinor-vitamin D compounds
US20060009425A1 (en) * 2004-05-28 2006-01-12 Leticia Delgado-Herrera Oral formulations of paricalcitol
US7094775B2 (en) 2004-06-30 2006-08-22 Bone Care International, Llc Method of treating breast cancer using a combination of vitamin D analogues and other agents
US20060003950A1 (en) * 2004-06-30 2006-01-05 Bone Care International, Inc. Method of treating prostatic diseases using a combination of vitamin D analogues and other agents
JP2008519808A (ja) 2004-11-12 2008-06-12 ビオエクセル エスピーエー 膀胱癌治療のためのビタミンｄ誘導体及び抗増殖薬の併用
AU2005309791A1 (en) * 2004-11-22 2006-06-01 Wisconsin Alumni Research Foundation 2-methylene-19,26,27-trinor-(20S)-1alpha-hydroxyvitamin D3 and its uses
BRPI0609630A2 (pt) * 2005-05-10 2010-04-20 Dermipsor Ltd composições e métodos para tratamento de doenças epidérmicas hiperproliferativas
EP1879449A4 (en) 2005-05-10 2009-12-16 Dermipsor Ltd SKIN CARE COMPOSITIONS AND METHODS
WO2007011951A2 (en) * 2005-07-18 2007-01-25 Teva Pharmaceutical Industries Ltd. Purification of paricalcitol
CN101405249B (zh) 2006-03-15 2013-05-29 日本迈科洛生物制药有限公司 茚衍生物的制备方法及其制备中间体
US20090281340A1 (en) * 2006-04-05 2009-11-12 Deluca Hector F 1alpha-hydroxy-2-(3'-hydroxypropylidene)-19-nor-vitamin d compounds and methods of making and treatment thereof
MX2008012701A (es) * 2006-04-05 2009-01-07 Wisconsin Alumni Res Found Compuestos de 1-alfa-hidroxi-2-(3'-hidroxipropiliden)-19-nor-vitam ina d y metodos de elaboracion y tratamiento de los mismos.
US20080051375A1 (en) * 2006-08-25 2008-02-28 Auerbach Alan H Methods for treating cancer comprising the administration of a vitamin d compound and an additional therapeutic agent, and compositions containing the same
US20080051380A1 (en) 2006-08-25 2008-02-28 Auerbach Alan H Methods and compositions for treating cancer
KR20090060306A (ko) 2006-08-25 2009-06-11 코우가 바이오테크놀로지, 인크. 비타민 ｄ 화합물 및 추가 치료제, 및 그를 함유하는 조성물을 투여하는 것을 포함하는, 암을 치료하는 방법
KR20090082257A (ko) 2006-11-02 2009-07-29 메루샹가부시키가이샤 1-히드록시-19-노르시클로비타민 ｄ 유도체의 제조방법 및 그 제조 중간체
US8987200B2 (en) * 2006-11-16 2015-03-24 Kai Pharmaceuticals, Inc. Polycationic calcium modulator peptides for the treatment of hyperparathyroidism and hypercalcemic disorders
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US20100075933A1 (en) * 2008-07-28 2010-03-25 Sunita Vijay Shelke Injectable compositions of vitamin d compounds
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US8664206B2 (en) 2010-03-23 2014-03-04 Wisconsin Alumni Research Foundation Diastereomers of 2-methylene-19-nor-22-methyl-1α,25-dihydroxyvitamin D3
CA2793727C (en) * 2010-03-23 2017-01-03 Wisconsin Alumni Research Foundation Diastereomers of 2-methylene-19-nor-22-methyl-1.alpha.,25-dihydroxyvitamin d3
AU2012262174B2 (en) 2011-06-03 2016-12-01 Wisconsin Alumni Research Foundation (22E)-2-methylene-26,27-cyclo-22-dehydro-1alpha-hydroxy-19-norvitamin D3 derivatives
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US20180265463A1 (en) * 2014-12-24 2018-09-20 Kyoto University Vitamin D3 Derivatives and Pharmaceutical Use Thereof
WO2017209934A1 (en) 2016-05-13 2017-12-07 Case Western Reserve University Autophagy activators for treating or preventing skin injury
JP2019522032A (ja) 2016-07-29 2019-08-08 ヤンセン ファーマシューティカ エヌ．ベー． 前立腺癌の治療方法
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US11903952B2 (en) 2020-05-27 2024-02-20 Northwestern University Vitamin D as an immune modulator to prevent immune-related complication from COVID-19 infection
US11932595B2 (en) 2020-09-17 2024-03-19 KYOTO UNIVERSITY, NATIONAL UNIVERSITY CORPORATION TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY, TEIKYO UNIVERSITY and THE UNIVERSITY OF TOKYO VDR-silent vitamin D derivative as inhibitors of SREBP and pharmaceutical use thereof

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US4448726A (en) * 1983-05-11 1984-05-15 Wisconsin Alumni Research Foundation Ring A- and triene-modified vitamin D compounds
US4769181A (en) * 1983-11-07 1988-09-06 Wisconsin Alumni Research Foundation 1,25-dihydroxyvitamin D2 compounds
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US4555364A (en) * 1984-11-01 1985-11-26 Wisconsin Alumni Research Foundation Method for preparing 1-hydroxyvitamin D compounds
CA1314872C (en) * 1986-04-25 1993-03-23 Toshio Nishizawa Fluorine derivatives of vitamin d _and process for producing the same
CA1333616C (en) * 1989-03-09 1994-12-20 Hector F. Deluca 19-nor-vitamin d compounds
US5246925A (en) * 1989-03-09 1993-09-21 Wisconsin Alumni Research Foundation 19-nor-vitamin D compounds for use in treating hyperparathyroidism
US5321018A (en) * 1989-03-09 1994-06-14 Wisconsin Alumni Research Foundation Use of 1α-hydroxylated-19-nor-vitamin D compounds to treat psoriasis
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US5086191A (en) * 1991-05-28 1992-02-04 Wisconsin Alumni Research Foundation Intermediates for the synthesis of 19-nor vitamin D compounds
AU650751B2 (en) * 1991-05-28 1994-06-30 Wisconsin Alumni Research Foundation Novel synthesis of 19-nor vitamin D compounds
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Also Published As

Publication number Publication date
HU9802116D0 (en) 1998-11-30
IL93455A0 (en) 1990-11-29
HU902307D0 (en) 1991-07-29
US5237110A (en) 1993-08-17
KR920700200A (ko) 1992-02-19
US5880113A (en) 1999-03-09
JPH0667899B2 (ja) 1994-08-31
RU2055068C1 (ru) 1996-02-27
US5587497A (en) 1996-12-24
RU2012558C1 (ru) 1994-05-15
HU215604B (hu) 1999-01-28
AU632315B2 (en) 1992-12-24
CA1333616C (en) 1994-12-20
US5618805A (en) 1997-04-08
JPH03505330A (ja) 1991-11-21
US5561123A (en) 1996-10-01
NO904854L (no) 1990-11-08
ZA907119B (en) 1991-10-30
US5633241A (en) 1997-05-27
KR950013636B1 (ko) 1995-11-13
AU5198890A (en) 1990-10-09
FI905489A0 (fi) 1990-11-06
HU222491B1 (hu) 2003-07-28
WO1990010620A1 (en) 1990-09-20
RO109331B1 (ro) 1995-01-30
US5710294A (en) 1998-01-20
IL93455A (en) 1994-12-29
HUT56538A (en) 1991-09-30
AR246254A1 (es) 1994-07-29
BR9004521A (pt) 1992-03-17

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