NO904404L - Fremgangsmaate ved fremstilling av 3-(l-pyroglutamyl)-l-tiazolidin-4-karboksylsyre samt derivater derav. - Google Patents

Fremgangsmaate ved fremstilling av 3-(l-pyroglutamyl)-l-tiazolidin-4-karboksylsyre samt derivater derav.

Info

Publication number
NO904404L
NO904404L NO90904404A NO904404A NO904404L NO 904404 L NO904404 L NO 904404L NO 90904404 A NO90904404 A NO 90904404A NO 904404 A NO904404 A NO 904404A NO 904404 L NO904404 L NO 904404L
Authority
NO
Norway
Prior art keywords
derivatives
thiazolidine
carboxylic acid
pyroglutamyl
procedure
Prior art date
Application number
NO90904404A
Other languages
English (en)
Other versions
NO904404D0 (no
NO178028C (no
NO178028B (no
Inventor
Stefano Poli
Lucio Del Corona
Original Assignee
Poli Ind Chimica Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Poli Ind Chimica Spa filed Critical Poli Ind Chimica Spa
Publication of NO904404D0 publication Critical patent/NO904404D0/no
Publication of NO904404L publication Critical patent/NO904404L/no
Publication of NO178028B publication Critical patent/NO178028B/no
Publication of NO178028C publication Critical patent/NO178028C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • C07K5/06173—Dipeptides with the first amino acid being heterocyclic and Glp-amino acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
NO904404A 1989-10-12 1990-10-11 Fremgangsmåte ved fremstilling av 3-(L-pyroglutamyl)-L-tiazolidin-4-karboksylsyre samt derivater derav NO178028C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT22003A IT1239029B (it) 1989-10-12 1989-10-12 Processo per la preparazione dell'acido 3-(l-piroglutamil)-l- tiazolidin-4-carbossilico e suoi derivati.

Publications (4)

Publication Number Publication Date
NO904404D0 NO904404D0 (no) 1990-10-11
NO904404L true NO904404L (no) 1991-04-15
NO178028B NO178028B (no) 1995-10-02
NO178028C NO178028C (no) 1996-01-10

Family

ID=11190043

Family Applications (1)

Application Number Title Priority Date Filing Date
NO904404A NO178028C (no) 1989-10-12 1990-10-11 Fremgangsmåte ved fremstilling av 3-(L-pyroglutamyl)-L-tiazolidin-4-karboksylsyre samt derivater derav

Country Status (18)

Country Link
US (1) US5110936A (no)
EP (1) EP0422566B1 (no)
JP (1) JP2813450B2 (no)
KR (1) KR100195895B1 (no)
AT (1) ATE121420T1 (no)
AU (1) AU644379B2 (no)
CA (1) CA2027341C (no)
DE (2) DE69018755T2 (no)
DK (1) DK0422566T3 (no)
ES (1) ES2028766T3 (no)
FI (1) FI95271C (no)
GR (1) GR910300072T1 (no)
HU (1) HU210213B (no)
IE (1) IE67047B1 (no)
IL (1) IL95949A (no)
IT (1) IT1239029B (no)
NO (1) NO178028C (no)
ZA (1) ZA908097B (no)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1230706B (it) * 1989-02-10 1991-10-29 Poli Ind Chimica Spa Derivati dell'acido 3 piroglutamoil tiazolidin 4 carbossilico e loro proprieta' farmacologiche.
IT1237998B (it) * 1990-01-23 1993-06-21 Poli Ind Chimica Spa Acido 3-l-(5-tioxo-l-prolil)tiazolidin-4-carbossilico e derivati, loro preparazione e composizioni farmaceutiche che li contengono
IT1270017B (it) * 1994-09-27 1997-04-16 Poli Ind Chimica Spa "sintesi quantitativa dell'acido 3-(l-piroglutamil)-l-tiazolidin-4- carbossilico e suoi derivati"
AU4335297A (en) * 1996-09-06 1998-03-26 Eli Lilly And Company Process and novel intermediates
US8404804B2 (en) * 2007-08-28 2013-03-26 Ipsen Pharma S.A.S. Methods and intermediates for chemical synthesis of polypeptides and proteins
CN102167727B (zh) * 2011-01-29 2013-05-15 浙江金立源药业有限公司 一种匹多莫德的合成方法
WO2016112977A1 (en) 2015-01-15 2016-07-21 Polichem S.A. Di-pidotimod benzathine and solid forms thereof
KR101642445B1 (ko) * 2016-01-11 2016-07-26 (주)남양통신 수상태양광 발전장치용 계류장치
CN107383162A (zh) * 2017-07-06 2017-11-24 成都美域高制药有限公司 一种匹多莫德的制备方法
CN108640912A (zh) * 2018-06-19 2018-10-12 广州大光制药有限公司 一种匹多莫德的工业化规模制备方法
CN111233854A (zh) * 2019-12-30 2020-06-05 常州寅盛药业有限公司 一种匹多莫德杂质的制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1202426B (it) * 1987-01-26 1989-02-09 Poli Ind Chimica Spa Derivato di acido tiazolidin-4-carbossilico,sua preparazione e composizioni farmaceutiche che lo contengono

Also Published As

Publication number Publication date
FI905011A0 (fi) 1990-10-11
EP0422566B1 (en) 1995-04-19
IT8922003A0 (it) 1989-10-12
HUT59136A (en) 1992-04-28
NO904404D0 (no) 1990-10-11
EP0422566A1 (en) 1991-04-17
US5110936A (en) 1992-05-05
KR910007923A (ko) 1991-05-30
IL95949A0 (en) 1991-07-18
DE422566T1 (de) 1991-09-05
IE67047B1 (en) 1996-02-21
ES2028766T3 (es) 1995-07-01
IE903599A1 (en) 1991-04-24
ZA908097B (en) 1991-08-28
NO178028C (no) 1996-01-10
AU644379B2 (en) 1993-12-09
ATE121420T1 (de) 1995-05-15
CA2027341A1 (en) 1991-04-13
FI95271B (fi) 1995-09-29
DE69018755D1 (de) 1995-05-24
KR100195895B1 (ko) 1999-06-15
IT8922003A1 (it) 1991-04-12
ES2028766T1 (es) 1992-07-16
GR910300072T1 (en) 1991-11-15
IT1239029B (it) 1993-09-20
CA2027341C (en) 2007-10-02
DK0422566T3 (da) 1995-06-26
NO178028B (no) 1995-10-02
JPH03193799A (ja) 1991-08-23
DE69018755T2 (de) 1995-08-24
JP2813450B2 (ja) 1998-10-22
IL95949A (en) 1995-10-31
HU906417D0 (en) 1991-04-29
HU210213B (en) 1995-02-28
AU6452190A (en) 1991-04-18
FI95271C (fi) 1996-01-10

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