NO870075L - Fremgangsmaate for fremstilling av terapeutisk aktive indol-derivater. - Google Patents

Fremgangsmaate for fremstilling av terapeutisk aktive indol-derivater.

Info

Publication number
NO870075L
NO870075L NO870075A NO870075A NO870075L NO 870075 L NO870075 L NO 870075L NO 870075 A NO870075 A NO 870075A NO 870075 A NO870075 A NO 870075A NO 870075 L NO870075 L NO 870075L
Authority
NO
Norway
Prior art keywords
procedure
preparation
therapeutic active
indol derivatives
indol
Prior art date
Application number
NO870075A
Other languages
English (en)
Norwegian (no)
Other versions
NO870075D0 (no
Inventor
Keith Mills
Colin David Eldred
Alexander William Oxford
Ian Harold Coates
David Emund Bays
Colin Frederick Webb
Michael Dennis Dowle
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of NO870075D0 publication Critical patent/NO870075D0/no
Publication of NO870075L publication Critical patent/NO870075L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO870075A 1986-01-08 1987-01-08 Fremgangsmaate for fremstilling av terapeutisk aktive indol-derivater. NO870075L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868600397A GB8600397D0 (en) 1986-01-08 1986-01-08 Chemical compounds

Publications (2)

Publication Number Publication Date
NO870075D0 NO870075D0 (no) 1987-01-08
NO870075L true NO870075L (no) 1987-07-09

Family

ID=10591074

Family Applications (1)

Application Number Title Priority Date Filing Date
NO870075A NO870075L (no) 1986-01-08 1987-01-08 Fremgangsmaate for fremstilling av terapeutisk aktive indol-derivater.

Country Status (23)

Country Link
US (1) US4855314A (OSRAM)
EP (1) EP0240096A1 (OSRAM)
JP (1) JPS62228056A (OSRAM)
KR (1) KR870007116A (OSRAM)
CN (1) CN1030409A (OSRAM)
AU (1) AU597325B2 (OSRAM)
BE (1) BE1000071A4 (OSRAM)
CH (1) CH672637A5 (OSRAM)
DE (1) DE3700408A1 (OSRAM)
DK (1) DK8787A (OSRAM)
FI (1) FI870062A7 (OSRAM)
FR (1) FR2595351B1 (OSRAM)
GB (2) GB8600397D0 (OSRAM)
HU (1) HU198685B (OSRAM)
IL (1) IL81201A (OSRAM)
IT (1) IT1205849B (OSRAM)
LU (1) LU86732A1 (OSRAM)
NL (1) NL8700026A (OSRAM)
NO (1) NO870075L (OSRAM)
NZ (1) NZ218868A (OSRAM)
PH (1) PH24741A (OSRAM)
PT (1) PT84075B (OSRAM)
ZA (1) ZA87105B (OSRAM)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8530507D0 (en) * 1985-12-11 1986-01-22 Glaxo Group Plc Chemical compounds
GB8600398D0 (en) * 1986-01-08 1986-02-12 Glaxo Group Ltd Chemical compounds
US5225431A (en) * 1987-10-23 1993-07-06 Burroughs Wellcome Co. Therapeutic substituted indole compounds and compositions thereof
GB8724912D0 (en) 1987-10-23 1987-11-25 Wellcome Found Indole derivatives
GB8819024D0 (en) * 1988-08-10 1988-09-14 Glaxo Group Ltd Chemical compounds
GB8823731D0 (en) * 1988-10-10 1988-11-16 Smith Kline French Lab Biologically active compounds
DK0486666T3 (da) * 1990-06-07 1998-03-30 Zeneca Ltd Terapeutisk heterocykliske forbindelser
US5607951A (en) * 1990-10-15 1997-03-04 Pfizer Inc Indole derivatives
AU651637B2 (en) * 1990-10-15 1994-07-28 Pfizer Inc. Indole derivatives
US5559129A (en) * 1990-10-15 1996-09-24 Pfizer Inc Indole derivatives
US5559246A (en) * 1990-10-15 1996-09-24 Pfizer Inc. Indole derivatives
US5545644A (en) * 1990-10-15 1996-08-13 Pfizer Inc. Indole derivatives
US5578612A (en) * 1990-10-15 1996-11-26 Pfizer Inc. Indole derivatives
CA2061520C (en) * 1991-03-27 2003-04-22 Lawrence J. Daher Delivery system for enhanced onset and increased potency
AU671959B2 (en) * 1991-11-25 1996-09-19 Pfizer Inc. Indole derivatives
TW288010B (OSRAM) * 1992-03-05 1996-10-11 Pfizer
US6380233B1 (en) 1992-04-07 2002-04-30 Pfizer Inc Indole derivatives as 5-HT1 agonists
WO1993020073A1 (en) 1992-04-07 1993-10-14 Pfizer Inc. Indole derivatives as 5-ht1 agonists
DE69307875T2 (de) * 1992-04-10 1997-05-22 Pfizer Acylaminoindolderivate als 5-ht1 agonisten
GB9207930D0 (en) * 1992-04-10 1992-05-27 Pfizer Ltd Indoles
GB9211277D0 (en) 1992-05-28 1992-07-15 Glaxo Group Inc Pharmaceutical compositions
TW251284B (OSRAM) * 1992-11-02 1995-07-11 Pfizer
FR2707639B1 (fr) * 1993-06-30 1995-10-13 Pf Medicament Nouveaux composés indoliques dérivés d'arylamines comme ligands sélectifs des récepteurs 5HT1D et 5HT1B.
ES2070772B1 (es) * 1993-08-09 1996-02-16 Pfizer Derivados de acilaminoindol
WO1995006636A1 (en) * 1993-08-31 1995-03-09 Pfizer Inc. 5-arylindole derivatives
US5468768A (en) * 1994-01-06 1995-11-21 Bristol-Myers Squibb Company Antimigraine derivatives of indolylcycloalkanylamines
GB9417310D0 (en) 1994-08-27 1994-10-19 Pfizer Ltd Therapeutic agents
FR2749846B1 (fr) * 1996-06-17 1998-09-11 Pf Medicament Sel de methanesulfonate d'une arylpiperazine derivee de tryptamine et ses solvates pour usage pharmaceutique
US7189753B1 (en) 1997-11-06 2007-03-13 Cady Roger K Preemptive prophylaxis of migraine
US5994352A (en) * 1998-11-13 1999-11-30 Pfizer Inc. 5-arylindole derivatives
AU2001280230A1 (en) * 2000-08-21 2002-03-04 Pacific Corporation Novel thiourea compounds and the pharmaceutical compositions containing the same
MXPA04012832A (es) * 2002-06-21 2005-05-27 Suven Life Sciences Ltd Arilsulfonil indoles novedosos que tienen afinidad por el receptor de la serotonina, utiles como agentes terapeuticos, proceso para su preparacion y composiciones farmaceuticas que los contienen.
US7317035B2 (en) 2002-06-21 2008-01-08 Suven Life Sciences Limited Tetracyclic arylcarbonyl indoles having serotonin receptor affinity useful as therapeutic agents, process for their preparation and pharmaceutical compositions containing them
US7297711B2 (en) * 2002-06-21 2007-11-20 Suven Life Sciences Limited Arylalkyl indoles having serotonin receptor affinity useful as therapeutic agents, process for their preparation and pharmaceutical compositions containing them
KR100818508B1 (ko) * 2002-11-28 2008-03-31 수벤 라이프 사이언시스 리미티드 세로토닌 수용체 친화력을 가지는 엔-아릴술포닐-3-치환인돌, 그 제조방법 및 그를 포함하는 약제학적 조성물
SI1567492T1 (sl) 2002-11-28 2013-07-31 Suven Life Sciences Limited N-arilsulfonil-3-aminoalkoksiindoli
PT1581538E (pt) * 2002-12-18 2007-05-31 Suven Life Sciences Ltd Indolos tetracíclicos substituidos na posição 3 que possuem afinidade pelo receptor de serotonina.
EP1572647B1 (en) * 2002-12-20 2016-09-21 Basf Se Synthesis of amines and intermediates for the synthesis thereof
MX2008015899A (es) 2006-06-12 2009-04-01 Novartis Ag Procedimiento para hacer sales de n-hidroxi-3-[4-[[[2-(2-metil-1h- indol-3-il)etil]amino]metil]fenil]-2e-2-propenamida.

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3472870A (en) * 1966-08-29 1969-10-14 Mead Johnson & Co Sulfonamidotryptamines
FR2334358A1 (fr) * 1975-12-12 1977-07-08 Sogeras Nouveaux medicaments derives de l'indole
ZA795239B (en) * 1978-10-12 1980-11-26 Glaxo Group Ltd Heterocyclic compounds
CH652394A5 (fr) * 1980-08-12 1985-11-15 Glaxo Group Ltd Derives indoliques, leur preparation et medicaments les renfermant.
ZW19381A1 (en) * 1980-08-12 1983-03-09 Glaxo Group Ltd Heterocyclic compounds
HU196752B (en) * 1983-12-06 1989-01-30 Glaxo Group Ltd Process for production of medical compositions containing indole-derivatives and these compounds
GB8332437D0 (en) * 1983-12-06 1984-01-11 Glaxo Group Ltd Chemical compounds
GB8332434D0 (en) * 1983-12-06 1984-01-11 Glaxo Group Ltd Production of chemical compounds
GB8600398D0 (en) * 1986-01-08 1986-02-12 Glaxo Group Ltd Chemical compounds

Also Published As

Publication number Publication date
PT84075B (pt) 1989-07-31
PH24741A (en) 1990-10-01
GB2185020A (en) 1987-07-08
US4855314A (en) 1989-08-08
FR2595351B1 (fr) 1990-07-13
LU86732A1 (fr) 1988-02-02
IT1205849B (it) 1989-03-31
CH672637A5 (OSRAM) 1989-12-15
IL81201A (en) 1991-06-10
GB8600397D0 (en) 1986-02-12
DE3700408A1 (de) 1987-07-09
GB2185020B (en) 1990-05-16
JPS62228056A (ja) 1987-10-06
AU6742087A (en) 1987-07-09
IL81201A0 (en) 1987-08-31
DK8787A (da) 1987-07-09
AU597325B2 (en) 1990-05-31
KR870007116A (ko) 1987-08-14
DK8787D0 (da) 1987-01-08
BE1000071A4 (fr) 1988-02-02
CN1030409A (zh) 1989-01-18
ZA87105B (en) 1987-09-30
FI870062A0 (fi) 1987-01-08
FR2595351A1 (fr) 1987-09-11
EP0240096A1 (en) 1987-10-07
FI870062A7 (fi) 1987-07-09
NL8700026A (nl) 1987-08-03
HUT46891A (en) 1988-12-28
HU198685B (en) 1989-11-28
NZ218868A (en) 1990-04-26
PT84075A (en) 1987-02-01
IT8747507A0 (it) 1987-01-08
NO870075D0 (no) 1987-01-08
GB8700382D0 (en) 1987-02-11

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