NO832667L - Fremgangsmaate ved fremstilling av 7alfa-acylthio-15,16-methylen-3-oxo-17alfa-pregna-1,4-dien-21,17-carbolactoner - Google Patents
Fremgangsmaate ved fremstilling av 7alfa-acylthio-15,16-methylen-3-oxo-17alfa-pregna-1,4-dien-21,17-carbolactonerInfo
- Publication number
- NO832667L NO832667L NO832667A NO832667A NO832667L NO 832667 L NO832667 L NO 832667L NO 832667 A NO832667 A NO 832667A NO 832667 A NO832667 A NO 832667A NO 832667 L NO832667 L NO 832667L
- Authority
- NO
- Norway
- Prior art keywords
- methylene
- carbolactones
- pregna
- acylthio
- oxo
- Prior art date
Links
- -1 15,16-methylene group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000006356 dehydrogenation reaction Methods 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000002906 microbiologic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
- C07J53/002—Carbocyclic rings fused
- C07J53/004—3 membered carbocyclic rings
- C07J53/008—3 membered carbocyclic rings in position 15/16
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19823227598 DE3227598A1 (de) | 1982-07-22 | 1982-07-22 | 7(alpha)-acylthio-15.16-methylen-3-oxo-17(alpha)-pregna-1.4-dien-21,17-carbolactone, verfahren zu ihrer herstellung und verwendung als arzneimittel |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO832667L true NO832667L (no) | 1984-01-23 |
| NO157297B NO157297B (no) | 1987-11-16 |
| NO157297C NO157297C (no) | 1988-02-24 |
Family
ID=6169184
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO832667A NO157297C (no) | 1982-07-22 | 1983-07-21 | Analogifremgangsmaate ved fremstilling av terapeutisk aktive 7alfa-acylthio-15,16-methylen-3-oxo-17alfa-pregna-1,4-dien-21,17-carbolactoner. |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US4500522A (no) |
| EP (1) | EP0099853B1 (no) |
| JP (1) | JPS5921699A (no) |
| AT (1) | ATE27606T1 (no) |
| AU (1) | AU557559B2 (no) |
| CA (1) | CA1202301A (no) |
| CS (1) | CS235333B2 (no) |
| DD (1) | DD210061B3 (no) |
| DE (2) | DE3227598A1 (no) |
| DK (1) | DK159457C (no) |
| ES (1) | ES524363A0 (no) |
| FI (1) | FI78112C (no) |
| GR (1) | GR78904B (no) |
| HU (1) | HU187114B (no) |
| IE (1) | IE55667B1 (no) |
| NO (1) | NO157297C (no) |
| ZA (1) | ZA835390B (no) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3481707D1 (de) * | 1983-08-17 | 1990-04-26 | Schering Ag | 7-alpha-substituierte 3-oxo-17alpha-pregn-4-en-21.17-carbolactone, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate. |
| DE3402329A1 (de) * | 1984-01-20 | 1985-08-01 | Schering AG, 1000 Berlin und 4709 Bergkamen | 6,6-ethylen-15,16-methylen-3-oxo-17(alpha)-pregn-4-en-21,17-carbolactone, verfahren zu deren herstellung und diese enthaltende pharmazeutische praeparate |
| DE3427090A1 (de) * | 1984-07-19 | 1986-01-23 | Schering AG, 1000 Berlin und 4709 Bergkamen | 7(alpha)-thiosubstituierte 19-hydroxy-15(beta),16(beta)-methylen-3-oxo-17(alpha)-pregn-4-en-21,17-carbolactone, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| DE3506100A1 (de) * | 1985-02-18 | 1986-08-21 | Schering AG, 1000 Berlin und 4709 Bergkamen | 1(alpha).7(alpha)-dithiosubstituierte spirolactone, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| JPS6248694A (ja) * | 1985-08-28 | 1987-03-03 | Shionogi & Co Ltd | 抗アルドステロン活性ステロイド誘導体 |
| DE3544661A1 (de) * | 1985-12-13 | 1987-06-19 | Schering Ag | Verfahren zur herstellung von 7(alpha)-acetylthiosteroiden |
| DE3718109A1 (de) * | 1987-05-27 | 1988-12-22 | Schering Ag | Verfahren zur trennung von verfahrensprodukten der mespirenonsynthese |
| JPH01165155U (no) * | 1988-05-02 | 1989-11-17 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE792624A (fr) * | 1972-05-22 | 1973-06-12 | Merck & Co Inc | Composes inhibiteurs de l'aldosterone et leur obtention |
| DE2237143A1 (de) * | 1972-07-28 | 1974-02-14 | Hoechst Ag | Verfahren zur herstellung von beta(3-keto-7alpha-acetylthio-17beta-hydroxy4-androsten-17alpha-yl)-propionsaeuregamma-lacton und dessen 1-dehydro-derivat |
| US3890304A (en) * | 1973-11-09 | 1975-06-17 | Searle & Co | 7{60 -carbam oyl-17-hydroxy-3-oxo-17{60 -pregn-4-ene-21-carboxylic acid {65 -lactone and related compounds |
| DE2652761C2 (de) * | 1976-11-16 | 1985-11-21 | Schering AG, 1000 Berlin und 4709 Bergkamen | 15,16-Methylen-Spirolactone, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel |
| DE2922500A1 (de) * | 1979-05-31 | 1980-12-04 | Schering Ag | 6 beta .7 beta |
-
1982
- 1982-07-22 DE DE19823227598 patent/DE3227598A1/de not_active Withdrawn
-
1983
- 1983-07-07 JP JP58122449A patent/JPS5921699A/ja active Granted
- 1983-07-12 AU AU16756/83A patent/AU557559B2/en not_active Ceased
- 1983-07-19 DD DD83253197A patent/DD210061B3/de not_active IP Right Cessation
- 1983-07-19 FI FI832627A patent/FI78112C/fi not_active IP Right Cessation
- 1983-07-20 GR GR71989A patent/GR78904B/el unknown
- 1983-07-20 AT AT83730074T patent/ATE27606T1/de not_active IP Right Cessation
- 1983-07-20 EP EP83730074A patent/EP0099853B1/en not_active Expired
- 1983-07-20 DE DE8383730074T patent/DE3371909D1/de not_active Expired
- 1983-07-21 NO NO832667A patent/NO157297C/no unknown
- 1983-07-21 CS CS835482A patent/CS235333B2/cs unknown
- 1983-07-21 HU HU832580A patent/HU187114B/hu unknown
- 1983-07-21 IE IE1708/83A patent/IE55667B1/en not_active IP Right Cessation
- 1983-07-21 DK DK335583A patent/DK159457C/da not_active IP Right Cessation
- 1983-07-21 CA CA000432905A patent/CA1202301A/en not_active Expired
- 1983-07-22 ZA ZA835390A patent/ZA835390B/xx unknown
- 1983-07-22 US US06/516,391 patent/US4500522A/en not_active Expired - Fee Related
- 1983-07-22 ES ES524363A patent/ES524363A0/es active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| FI78112C (fi) | 1989-06-12 |
| ZA835390B (en) | 1984-03-28 |
| FI832627A0 (fi) | 1983-07-19 |
| EP0099853A3 (en) | 1984-04-18 |
| FI832627L (fi) | 1984-01-23 |
| CS235333B2 (en) | 1985-05-15 |
| IE55667B1 (en) | 1990-12-19 |
| AU1675683A (en) | 1984-01-26 |
| NO157297B (no) | 1987-11-16 |
| AU557559B2 (en) | 1986-12-24 |
| DK159457B (da) | 1990-10-15 |
| DK335583D0 (da) | 1983-07-21 |
| ATE27606T1 (de) | 1987-06-15 |
| EP0099853A2 (en) | 1984-02-01 |
| ES8407322A1 (es) | 1984-10-01 |
| FI78112B (fi) | 1989-02-28 |
| DE3227598A1 (de) | 1984-01-26 |
| JPH0372080B2 (no) | 1991-11-15 |
| EP0099853B1 (en) | 1987-06-03 |
| DK159457C (da) | 1991-03-18 |
| ES524363A0 (es) | 1984-10-01 |
| DD210061B3 (de) | 1988-11-30 |
| CA1202301A (en) | 1986-03-25 |
| DK335583A (da) | 1984-01-23 |
| DD210061A5 (de) | 1984-05-30 |
| GR78904B (no) | 1984-10-02 |
| US4500522A (en) | 1985-02-19 |
| DE3371909D1 (en) | 1987-07-09 |
| NO157297C (no) | 1988-02-24 |
| IE831708L (en) | 1984-01-22 |
| JPS5921699A (ja) | 1984-02-03 |
| HU187114B (en) | 1985-11-28 |
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