NO831447L - Nye mellomprodukter, fremgangsmaate for fremstilling derav og anvendelse derav - Google Patents

Nye mellomprodukter, fremgangsmaate for fremstilling derav og anvendelse derav

Info

Publication number
NO831447L
NO831447L NO831447A NO831447A NO831447L NO 831447 L NO831447 L NO 831447L NO 831447 A NO831447 A NO 831447A NO 831447 A NO831447 A NO 831447A NO 831447 L NO831447 L NO 831447L
Authority
NO
Norway
Prior art keywords
procedures
producing
intermediate products
new intermediate
alkylnorscopolamines
Prior art date
Application number
NO831447A
Other languages
English (en)
Other versions
NO159172C (no
NO159172B (no
Inventor
Rolf Banholzer
Original Assignee
Boehringer Ingelheim Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Kg filed Critical Boehringer Ingelheim Kg
Publication of NO831447L publication Critical patent/NO831447L/no
Publication of NO159172B publication Critical patent/NO159172B/no
Publication of NO159172C publication Critical patent/NO159172C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Mushroom Cultivation (AREA)
  • Preparation Of Fruits And Vegetables (AREA)
  • Saccharide Compounds (AREA)
NO831447A 1982-04-26 1983-04-25 Nye n-alkyl-norskopiner. NO159172C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19823215493 DE3215493A1 (de) 1982-04-26 1982-04-26 Neue zwischenprodukte, verfahren zu ihrer herstellung und ihre verwendung

Publications (3)

Publication Number Publication Date
NO831447L true NO831447L (no) 1983-10-27
NO159172B NO159172B (no) 1988-08-29
NO159172C NO159172C (no) 1988-12-07

Family

ID=6161961

Family Applications (1)

Application Number Title Priority Date Filing Date
NO831447A NO159172C (no) 1982-04-26 1983-04-25 Nye n-alkyl-norskopiner.

Country Status (24)

Country Link
US (1) US4783534A (no)
EP (1) EP0092814B1 (no)
JP (1) JPS58201779A (no)
KR (1) KR900004127B1 (no)
AT (1) ATE16185T1 (no)
AU (1) AU557680B2 (no)
CA (1) CA1254566A (no)
CS (1) CS236873B2 (no)
DD (1) DD211114A5 (no)
DE (2) DE3215493A1 (no)
DK (1) DK159777C (no)
ES (1) ES521809A0 (no)
FI (1) FI831234L (no)
GR (1) GR78837B (no)
HU (1) HU193161B (no)
IE (1) IE55308B1 (no)
IL (1) IL68479A0 (no)
NO (1) NO159172C (no)
NZ (1) NZ203980A (no)
PH (1) PH23301A (no)
PL (1) PL138718B1 (no)
PT (1) PT76584B (no)
YU (1) YU43731B (no)
ZA (1) ZA832883B (no)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4021847C2 (de) * 1990-07-09 1994-09-08 Stockhausen Chem Fab Gmbh Verfahren zur Herstellung wasserquellbarer Produkte unter Verwendung von Feinstanteilen wasserquellbarer Polymerer
CZ20023537A3 (cs) * 2000-04-27 2003-02-12 Boehringer Ingelheim Pharma Kg Betamimetika, způsob jejich výroby a použití jako farmaceutický prostředek
EP1430887A1 (de) * 2000-10-12 2004-06-23 Boehringer Ingelheim Pharma GmbH & Co.KG Tiotropium-haltige Inhalationspulver
US6908928B2 (en) 2000-10-12 2005-06-21 Bi Pharma Kg. Crystalline tiotropium bromide monohydrate, processes for the preparation thereof, and pharmaceutical compositions
US6852728B2 (en) 2000-10-14 2005-02-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg Anticholinergics, processes for preparing them, and pharmaceutical compositions containing them
US6706726B2 (en) * 2000-10-14 2004-03-16 Boehringer Ingelheim Pharma Gmbh & Co. Kg Anticholinergics which may be used as medicaments as well as processes for preparing them
US20020111363A1 (en) * 2000-10-31 2002-08-15 Karin Drechsel Inhalable formulation of a solution containing a tiotropium salt
US20020151541A1 (en) * 2000-10-31 2002-10-17 Michel Pairet Pharmaceutical compositions containing tiotropium salts and antihistamines and their use
US20020137764A1 (en) * 2000-10-31 2002-09-26 Karin Drechsel Inhalable formulation of a solution containing a tiotropium salt
DE10062712A1 (de) * 2000-12-15 2002-06-20 Boehringer Ingelheim Pharma Neue Arzneimittelkompositionen auf der Basis von Anticholinergika und Corticosteroiden
US7776315B2 (en) * 2000-10-31 2010-08-17 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pharmaceutical compositions based on anticholinergics and additional active ingredients
US20020193392A1 (en) * 2000-11-13 2002-12-19 Christel Schmelzer Pharmaceutical compositions based on tiotropium salts of salts of salmeterol
US20100310477A1 (en) * 2000-11-28 2010-12-09 Boehringer Ingelheim Pharma Gmbh & Co. Kg. Pharmaceutical compositions based on anticholingerics and additional active ingredients
US20030013675A1 (en) * 2001-05-25 2003-01-16 Boehringer Ingelheim Pharma Kg Combination of an adenosine A2A-receptor agonist and tiotropium or a derivative thereof for treating obstructive airways and other inflammatory diseases
US20030070679A1 (en) * 2001-06-01 2003-04-17 Boehringer Ingelheim Pharma Kg Capsules containing inhalable tiotropium
US20030018019A1 (en) * 2001-06-23 2003-01-23 Boehringer Ingelheim Pharma Kg Pharmaceutical compositions based on anticholinergics, corticosteroids and betamimetics
DE10141377A1 (de) * 2001-08-23 2003-03-13 Boehringer Ingelheim Pharma Aufstreuverfahren zur Herstellung von Pulverformulierungen
US6919325B2 (en) * 2001-09-14 2005-07-19 Boehringer Ingelheim Pharma Kg Pharmaceutical compositions containing tiotropium salts and low-solubility salmeterol salts
DE10200943A1 (de) 2002-01-12 2003-07-24 Boehringer Ingelheim Pharma Verfahren zur Herstellung von Scopinestern
US7405224B2 (en) * 2002-01-31 2008-07-29 Boehringer Ingelheim Pharma Gmbh & Co. Kg Xanthenecarboxylates, processes for preparing them, and their use as pharmaceutical compositions
US6790856B2 (en) * 2002-01-31 2004-09-14 Boehringer Ingelheim Pharma Kg Fluorenecarboxylic acid esters, process for the manufacture thereof, and use thereof as medicaments
US7309707B2 (en) * 2002-03-20 2007-12-18 Boehringer Ingelheim Pharma Gmbh & Co. Kg Crystalline micronisate, process for the manufacture thereof and use thereof for the preparation of a medicament
US7244415B2 (en) * 2002-03-28 2007-07-17 Boehringer Ingelheim Pharma Gmbh & Co. Kg HFA suspension formulations of an anhydrate
US7311894B2 (en) * 2002-03-28 2007-12-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg HFA suspension formulations containing an anticholinergic
ES2272968T3 (es) * 2002-04-04 2007-05-01 BOEHRINGER INGELHEIM PHARMA GMBH &amp; CO.KG Formulaciones en polvo, adecuadas para inhalacion.
US20030235538A1 (en) 2002-04-09 2003-12-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Method for the administration of an anticholinergic by inhalation
US7417051B2 (en) * 2002-04-12 2008-08-26 Boehringer Ingelheim Pharma Gmbh & Co. Kg Medicaments comprising betamimetics and a novel anticholinergic
US7084153B2 (en) * 2002-04-12 2006-08-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg Medicaments comprising steroids and a novel anticholinergic
US7763280B2 (en) * 2002-11-28 2010-07-27 Boehringer Ingelheim Pharma Gmbh & Co. Kg Tiotropium containing powder formulation for inhalation
DE10345065A1 (de) * 2003-09-26 2005-04-14 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosolformulierung für die Inhalation enthaltend ein Anticholinergikum
SE0303570L (sv) * 2003-12-03 2005-06-04 Microdrug Ag Fukt-känslig medicinsk produkt
TWI274641B (en) * 2005-08-30 2007-03-01 Rexon Ind Corp Ltd Cutting machine
CN115572291A (zh) * 2022-09-28 2023-01-06 成都第一制药有限公司 一种氢溴酸山莨菪碱及其制备方法和质量控制方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3211185A1 (de) * 1982-03-26 1983-09-29 Boehringer Ingelheim KG, 6507 Ingelheim Neue quartaere 6,11-dihydro-dibenzo-(b,e)-thiepin-11-n-alkyl- norscopinether und verfahren zu deren herstellung

Also Published As

Publication number Publication date
PT76584B (de) 1986-02-27
GR78837B (no) 1984-10-02
DK182583A (da) 1983-10-27
PT76584A (de) 1983-05-01
AU1394583A (en) 1983-11-03
NO159172C (no) 1988-12-07
JPH052678B2 (no) 1993-01-13
NZ203980A (en) 1986-02-21
ES8402292A1 (es) 1984-01-16
DE3215493A1 (de) 1983-11-03
CS236873B2 (en) 1985-05-15
YU43731B (en) 1989-10-31
FI831234L (fi) 1983-10-27
DK182583D0 (da) 1983-04-25
AU557680B2 (en) 1987-01-08
IL68479A0 (en) 1983-07-31
PH23301A (en) 1989-06-30
DD211114A5 (de) 1984-07-04
NO159172B (no) 1988-08-29
DK159777B (da) 1990-12-03
US4783534A (en) 1988-11-08
CA1254566A (en) 1989-05-23
ZA832883B (en) 1984-12-24
DE3361054D1 (en) 1985-11-28
HU193161B (en) 1987-08-28
JPS58201779A (ja) 1983-11-24
EP0092814B1 (de) 1985-10-23
IE830938L (en) 1983-10-26
PL241635A1 (en) 1983-11-21
IE55308B1 (en) 1990-08-01
PL138718B1 (en) 1986-10-31
YU93983A (en) 1985-10-31
KR900004127B1 (ko) 1990-06-16
KR840004425A (ko) 1984-10-15
DK159777C (da) 1991-04-22
EP0092814A1 (de) 1983-11-02
ATE16185T1 (de) 1985-11-15
FI831234A0 (fi) 1983-04-13
ES521809A0 (es) 1984-01-16

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