NO830238L - PROCEDURE FOR THE PREPARATION OF PHARMACOLOGICALLY ACTIVE URINENTS AND TIOUR INGREDIENTS - Google Patents

PROCEDURE FOR THE PREPARATION OF PHARMACOLOGICALLY ACTIVE URINENTS AND TIOUR INGREDIENTS

Info

Publication number
NO830238L
NO830238L NO830238A NO830238A NO830238L NO 830238 L NO830238 L NO 830238L NO 830238 A NO830238 A NO 830238A NO 830238 A NO830238 A NO 830238A NO 830238 L NO830238 L NO 830238L
Authority
NO
Norway
Prior art keywords
urinents
tiour
ingredients
procedure
preparation
Prior art date
Application number
NO830238A
Other languages
Norwegian (no)
Other versions
NO158417C (en
NO158417B (en
Inventor
Vern Gordon Devries
Elwood Eugene Largis
Ransom Brown Conrow
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/342,693 external-priority patent/US4473579A/en
Priority claimed from US06/342,698 external-priority patent/US4387105A/en
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of NO830238L publication Critical patent/NO830238L/en
Publication of NO158417B publication Critical patent/NO158417B/en
Publication of NO158417C publication Critical patent/NO158417C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C273/00—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C273/18—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas
    • C07C273/1809—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas with formation of the N-C(O)-N moiety
    • C07C273/1818—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas with formation of the N-C(O)-N moiety from -N=C=O and XNR'R"
    • C07C273/1827—X being H
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Furan Compounds (AREA)
NO830238A 1982-01-26 1983-01-25 ANALOGUE PROCEDURE FOR THE PREPARATION OF PHARMACOLOGICALLY ACTIVE URINENTS AND TIOUR INGREDIENTS. NO158417C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/342,693 US4473579A (en) 1982-01-26 1982-01-26 Antiatherosclerotic tetrasubstituted ureas and thioureas
US06/342,698 US4387105A (en) 1982-01-26 1982-01-26 Methods of treating atherosclerosis with dialkylureas and dialkylthioureas

Publications (3)

Publication Number Publication Date
NO830238L true NO830238L (en) 1983-07-27
NO158417B NO158417B (en) 1988-05-30
NO158417C NO158417C (en) 1988-09-07

Family

ID=26993144

Family Applications (1)

Application Number Title Priority Date Filing Date
NO830238A NO158417C (en) 1982-01-26 1983-01-25 ANALOGUE PROCEDURE FOR THE PREPARATION OF PHARMACOLOGICALLY ACTIVE URINENTS AND TIOUR INGREDIENTS.

Country Status (20)

Country Link
KR (1) KR890001808B1 (en)
AT (1) AT391313B (en)
AU (1) AU562699B2 (en)
CH (1) CH654571A5 (en)
DE (1) DE3247581A1 (en)
DK (1) DK160869C (en)
ES (2) ES519246A0 (en)
FI (1) FI85013C (en)
FR (1) FR2521134B1 (en)
GB (1) GB2113684B (en)
GR (1) GR77186B (en)
HU (1) HU200746B (en)
IE (1) IE54683B1 (en)
IL (1) IL67417A (en)
IT (1) IT1203647B (en)
NL (1) NL8300269A (en)
NO (1) NO158417C (en)
PL (1) PL143836B1 (en)
PT (1) PT76138A (en)
SE (1) SE462653B (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2138804A (en) * 1983-04-27 1984-10-31 Sumitomo Chemical Co Fungicidal N-phenylcarbamates
GB2149394B (en) * 1983-07-19 1986-09-24 American Cyanamid Co Ureas
US4818899A (en) * 1986-12-03 1989-04-04 Minnesota Mining And Manufacturing Company Second harmonic generation by carbamic acid derivatives
US5116848A (en) * 1988-03-30 1992-05-26 Warner-Lambert Company N-(((2,6-disubstituted)phenyl)-n-diarylalkyl)ureas as antihyperlipidemic and antiatherosclerotic agents
ES2060682T3 (en) * 1988-03-30 1994-12-01 Warner Lambert Co N - ((FENIL (2,6-DISUBSTITUTED)) - N'-ARIL) UREAS AS ANTI-HYPERCHOLESTEROLEMIC AND ANTIATHEROSCLEROTIC AGENTS.
CA2076012A1 (en) * 1990-02-14 1991-08-15 Yasuyuki Kato Agent for inhibiting the formation of denatured ldl
US5668136A (en) * 1990-09-25 1997-09-16 Eisai Co., Ltd. Trisubstituted benzene derivatives, composition and methods of treatment
HUT62558A (en) * 1991-07-01 1993-05-28 Sandoz Ag Process for producing n-phenylthiourea derivaties and pharmaceutical compositions comprising same
DE69314929T2 (en) * 1992-07-20 1998-03-19 Eisai Co Ltd BENZENE DERIVATIVES
JP2003524574A (en) * 1997-08-05 2003-08-19 ノボ ノルディスク アクティーゼルスカブ 2,5- and 3,5-disubstituted aniline derivatives, their preparation and use
US6455566B1 (en) 1997-09-03 2002-09-24 Wyeth Substituted 1-aryl-3-heteroaryl-thioureas (or isothioureas) as antiatherosclerotic agents
TW415942B (en) * 1997-09-03 2000-12-21 American Home Prod Novel substituted 1-aryl-3-heteroaryl-thioureas and substituted 1-aryl-3-heteroaryl-isothioureas as antiatherosclerotic agents
CA2284864A1 (en) * 1998-01-21 1999-07-29 Zymogenetics, Inc. Dialkyl ureas as calcitonin mimetics
US8324396B2 (en) * 2007-07-10 2012-12-04 Amgen Inc. Derivatives of urea and related diamines, methods for their manufacture, and uses therefor

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL212631A (en) * 1949-12-06
US2688039A (en) * 1952-02-08 1954-08-31 Ciba Pharm Prod Inc Halogen-containing di-(substituted phenyl)-thioureas
US3326663A (en) * 1964-09-25 1967-06-20 Shell Oil Co Herbicidal phenylureas
US3335142A (en) * 1965-07-07 1967-08-08 American Cyanamid Co Process for the preparation of n, n'-disubstituted ureas
US3659012A (en) * 1969-05-26 1972-04-25 Lilly Co Eli Methods of treating helminth infections with thiourea derivatives
US3728386A (en) * 1970-07-27 1973-04-17 Exxon Research Engineering Co N-cycloalkylalkyl and n-cycloalkyl substituted phenyl ureas and halo acetamides
US3928437A (en) * 1970-09-02 1975-12-23 Ciba Geigy Corp Phenoxy-phenyl, phenylthiophenyl, phenylsulfonylphenyl and phenylaminophenyl diaminothioureas
US3856952A (en) * 1973-03-01 1974-12-24 Pennwalt Corp Synergistic antimicrobial compositions employing certain n-(phenyl-carbamyl)amino-benzene sulfonyl flourides
US3903130A (en) * 1974-05-03 1975-09-02 Stauffer Chemical Co 1-Trifluormethylphenyl-3-dicyanophenyl urea
DE2928485A1 (en) * 1979-07-14 1981-01-29 Bayer Ag USE OF UREA DERIVATIVES AS A MEDICINAL PRODUCT IN THE TREATMENT OF FATTY METABOLISM DISORDERS

Also Published As

Publication number Publication date
NO158417C (en) 1988-09-07
GR77186B (en) 1984-09-11
AU1068183A (en) 1983-08-04
KR890001808B1 (en) 1989-05-23
SE462653B (en) 1990-08-06
GB8301863D0 (en) 1983-02-23
AU562699B2 (en) 1987-06-18
DK28683D0 (en) 1983-01-25
IL67417A (en) 1989-10-31
NO158417B (en) 1988-05-30
PT76138A (en) 1983-02-01
HU200746B (en) 1990-08-28
IE54683B1 (en) 1990-01-03
DK160869C (en) 1991-10-14
SE8300370L (en) 1983-07-27
NL8300269A (en) 1983-08-16
ATA23983A (en) 1990-03-15
DK160869B (en) 1991-04-29
ES531508A0 (en) 1985-07-01
FI85013C (en) 1992-02-25
PL240284A1 (en) 1985-01-02
FR2521134A1 (en) 1983-08-12
DK28683A (en) 1983-07-27
ES8406422A1 (en) 1984-08-01
GB2113684B (en) 1985-12-18
KR840002773A (en) 1984-07-16
IT1203647B (en) 1989-02-15
ES519246A0 (en) 1984-08-01
GB2113684A (en) 1983-08-10
CH654571A5 (en) 1986-02-28
PL143836B1 (en) 1988-03-31
FI830247L (en) 1983-07-27
DE3247581A1 (en) 1983-08-04
ES8505943A1 (en) 1985-07-01
IE830146L (en) 1983-07-26
SE8300370D0 (en) 1983-01-25
IT8347605A0 (en) 1983-01-25
FI830247A0 (en) 1983-01-25
AT391313B (en) 1990-09-25
FR2521134B1 (en) 1987-01-09
FI85013B (en) 1991-11-15

Similar Documents

Publication Publication Date Title
NO841568L (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE PHENETANOLAMINE DERIVATIVES
NO850521L (en) PROCEDURE FOR THE PREPARATION OF PHARMACOLOGICALLY ACTIVE DIESTERS
NO161002C (en) ANALOGUE PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE POLYPEPTIDES.
NO157738C (en) ANALOGUE PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY ACTIVE BENZOCSAZINONES AND BENZOCSAZOLINONES.
NO852729L (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY EFFECTIVE BENZIMIDAZOLE AND BENZOTIAZOLD DERIVATIVES
NO161317C (en) ANALOGUE PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE OXICAMS.
NO834089L (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE COMPOUNDS OF PLATINA AND PALLADIUM
NO830238L (en) PROCEDURE FOR THE PREPARATION OF PHARMACOLOGICALLY ACTIVE URINENTS AND TIOUR INGREDIENTS
NO883750L (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE PIPERIDE INGREDIENTS.
NO862373D0 (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE TIENOPYRIDONES.
NO841542L (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE INDENO-PYRIDAZINON DERIVATIVES
NO158460C (en) ANALOGUE PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE RELATIONS.
NO862141L (en) PROCEDURE FOR THE PREPARATION OF ACTIVE CINNOLINE DERIVATIVES
NO854369L (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE BENZIMIDAZOLE DERIVATIVES
NO843042L (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE CUMARIN DERIVATIVES
NO834729L (en) PROCEDURE FOR THE PREPARATION OF PHARMACOLOGICALLY ACTIVE TIO-CEPHALOSPORINES
NO833527L (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE PHENYL-CYCLOBUTYL DERIVATIVES
NO843377L (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE AZUREND DERIVATIVES
NO820112L (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE PYRIDOINDOL DERIVATIVES
IT1164180B (en) N-CARBAMOYLIC DERIVATIVES OF ISOTHIAZOLE- (5,4B) PIRIDIN-ONE-3 AND THEIR PREPARATION PROCEDURE
NO163570C (en) ANALOGUE PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE ACYLAMINOMITOSANES.
NO162188C (en) ANALOGUE PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE IMIDAZOKINOLINES.
NO845148L (en) PROCEDURE FOR THE PREPARATION OF 16-PHENOXY AND 16-SUBSTITUTED-PHENOXY-PROSTATRIC ACID DERIVATIVES
NO834437L (en) PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE SPIRO-3-HETERO-AZOLON DERIVATIVES
NO831807L (en) PROCEDURES FOR THE PREPARATION OF THERAPEUTIC ACTIVE DIHYDROPYRIDINES AND INTERMEDIATES OF THE PROCEDURES