NO336231B1 - Anvendelse av Cop-1 for fremstilling av en vaksine for behandling av amyotrofisk lateral sklerose (ALS). - Google Patents

Anvendelse av Cop-1 for fremstilling av en vaksine for behandling av amyotrofisk lateral sklerose (ALS). Download PDF

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Publication number
NO336231B1
NO336231B1 NO20042833A NO20042833A NO336231B1 NO 336231 B1 NO336231 B1 NO 336231B1 NO 20042833 A NO20042833 A NO 20042833A NO 20042833 A NO20042833 A NO 20042833A NO 336231 B1 NO336231 B1 NO 336231B1
Authority
NO
Norway
Prior art keywords
cop
mice
als
vaccine
immunized
Prior art date
Application number
NO20042833A
Other languages
English (en)
Norwegian (no)
Other versions
NO20042833L (no
Inventor
Michal Eisenbach-Schwartz
Esther Yoles
Original Assignee
Yeda Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yeda Res & Dev filed Critical Yeda Res & Dev
Publication of NO20042833L publication Critical patent/NO20042833L/no
Publication of NO336231B1 publication Critical patent/NO336231B1/no

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0008Antigens related to auto-immune diseases; Preparations to induce self-tolerance
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0007Nervous system antigens; Prions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Rheumatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
NO20042833A 2001-12-06 2004-07-05 Anvendelse av Cop-1 for fremstilling av en vaksine for behandling av amyotrofisk lateral sklerose (ALS). NO336231B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33613901P 2001-12-06 2001-12-06
PCT/IL2002/000979 WO2003047500A2 (en) 2001-12-06 2002-12-05 Vaccine and method for treatment of motor neurone diseases

Publications (2)

Publication Number Publication Date
NO20042833L NO20042833L (no) 2004-08-12
NO336231B1 true NO336231B1 (no) 2015-06-22

Family

ID=23314742

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20042833A NO336231B1 (no) 2001-12-06 2004-07-05 Anvendelse av Cop-1 for fremstilling av en vaksine for behandling av amyotrofisk lateral sklerose (ALS).

Country Status (24)

Country Link
US (1) US7351686B2 (xx)
EP (1) EP1429800B1 (xx)
JP (1) JP4542339B2 (xx)
KR (1) KR20040081431A (xx)
CN (2) CN102151330B (xx)
AT (1) ATE422362T1 (xx)
AU (1) AU2002353486B2 (xx)
CA (1) CA2469092C (xx)
CY (1) CY1109044T1 (xx)
DE (1) DE60231131D1 (xx)
DK (1) DK1429800T3 (xx)
ES (1) ES2322566T3 (xx)
HK (1) HK1067043A1 (xx)
HU (1) HU228207B1 (xx)
IL (1) IL160105A0 (xx)
IS (1) IS2670B (xx)
MX (1) MXPA04005537A (xx)
NO (1) NO336231B1 (xx)
NZ (1) NZ533356A (xx)
PL (1) PL205469B1 (xx)
PT (1) PT1429800E (xx)
RU (1) RU2303996C2 (xx)
SI (1) SI1429800T1 (xx)
WO (1) WO2003047500A2 (xx)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7399740B2 (en) 2001-06-28 2008-07-15 Yeda Research And Development Co. Ltd. Poly-Glu,Tyr for neuroprotective therapy
ATE548045T1 (de) * 2003-01-07 2012-03-15 Yeda Res & Dev Vakzine in augentropfenform enthaltend copolymer 1 für die therapeutische immunisierung
EP1684797A1 (en) 2003-11-12 2006-08-02 Yeda Research and Development Co. Ltd. Vaccine and method for treatment of neurodegenerative diseases
JP4808631B2 (ja) 2003-12-09 2011-11-02 イエダ リサーチ アンド デベロップメント カンパニー リミテッド 精神医学的障害の治療用のコポリマー1を含む方法及びワクチン
CA2558380A1 (en) * 2004-03-03 2005-09-15 Teva Pharmaceutical Industries, Ltd. Combination therapy with glatiramer acetate and riluzole
WO2005120542A2 (en) * 2004-05-07 2005-12-22 Peptimmune, Inc. Methods of treating disease with random copolymers
US7655221B2 (en) 2004-05-07 2010-02-02 Peptimmune, Inc. Methods of treating disease with random copolymers
JP5241012B2 (ja) * 2005-07-15 2013-07-17 ノバルティス アーゲー Pamps、病原体関連分子パターン
CN100448481C (zh) * 2006-06-22 2009-01-07 中国科学院遗传与发育生物学研究所 xCT蛋白及其编码基因的新用途
WO2009040814A1 (en) 2007-09-24 2009-04-02 Hadasit Medical Research Services & Development Ltd Use of copolymer 1 for treatment of muscular dystrophy
USRE49251E1 (en) 2010-01-04 2022-10-18 Mapi Pharma Ltd. Depot systems comprising glatiramer or pharmacologically acceptable salt thereof
US8759302B2 (en) 2010-03-16 2014-06-24 Teva Pharmaceutical Industries, Ltd. Methods of treating a subject afflicted with an autoimmune disease using predictive biomarkers of clinical response to glatiramer acetate therapy in multiple sclerosis
MX347871B (es) 2010-10-11 2017-05-16 Teva Pharmaceutical Ind Ltd * Biomarcadores de citoquina como marcadores predictivos de respuesta clínica para acetato de glatirámero.
ES2601892T3 (es) 2011-04-21 2017-02-16 Mapi Pharma Limited Pentapolímero aleatorio para el tratamiento de enfermedades autoinmunes
EA201490749A1 (ru) 2011-10-10 2014-09-30 Тева Фармасьютикал Индастриз Лтд. Однонуклеотидные полиморфизмы, полезные для прогнозирования клинической реакции на глатирамера ацетат
US9861686B2 (en) * 2011-12-05 2018-01-09 Ben-Gurion University Of The Negev Research & Development Authority Diagnostic and therapeutic methods and their application in amyotrophic lateral sclerosis (ALS)
CA2907909A1 (en) * 2012-03-26 2013-10-03 Neuroquest Ltd. Cellular markers for diagnosis of alzheimer's disease and for alzheimer's disease progression
WO2014037952A1 (en) 2012-09-10 2014-03-13 Yeda Research And Development Co. Ltd At The Weizmann Institute Of Science Individualized immunomodulation therapy for neurodegenerative disorders, cns injury and age-related dementia
MX2019010174A (es) 2017-03-26 2019-10-15 Mapi Pharma Ltd Sistemas de deposito de glatiramer para el tratamiento de formas progresivas de esclerosis multiple.

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL36670A (en) * 1971-04-21 1974-09-10 Sela M Therapeutic basic copolymers of amino acids
US3849650A (en) 1973-03-29 1974-11-19 Picker Corp Automatic x-ray inspection system
US5800808A (en) * 1994-05-24 1998-09-01 Veda Research And Development Co., Ltd. Copolymer-1 improvements in compositions of copolymers
SE505316C2 (sv) 1995-10-17 1997-08-04 Kenneth G Haglid Användning av proteinet S-100b för framställning av läkemedel för nervceller
US20030108528A1 (en) 1998-05-19 2003-06-12 Michal Eisenbach-Schwartz Activated t-cells, nervous system-specific antigens and their uses
US20020072493A1 (en) 1998-05-19 2002-06-13 Yeda Research And Development Co. Ltd. Activated T cells, nervous system-specific antigens and their uses
CA2328612A1 (en) 1998-05-19 1999-11-25 Yeda Research And Development Co., Ltd. Activated t cells, nervous system-specific antigens and their uses
JP2002500199A (ja) 1998-07-21 2002-01-08 イェダ リサーチ アンド デベロップメント カンパニー リミテッド 活性化t細胞、及びそれらの用途
WO2000005249A2 (en) 1998-07-23 2000-02-03 The President And Fellows Of Harvard College Synthetic peptides and methods of use for autoimmune disease therapies
ES2243450T3 (es) * 2000-01-20 2005-12-01 Yeda Research And Development Co. Ltd. El uso de copolimero 1 y peptidos y polipeptidos relacionados, y de celulas t tratadas con los mismos, para terapia neuroprotectora.
US20020037848A1 (en) * 2000-06-07 2002-03-28 Michal Eisenbach-Schwartz Use of copolymer 1 and related peptides and polypeptides and T cells treated therewith for neuroprotective therapy
WO2002076503A1 (en) * 2000-06-20 2002-10-03 Mayo Foundation For Medical Education And Research Treatment of central nervous system diseases by antibodies against glatiramer acetate
US7399740B2 (en) * 2001-06-28 2008-07-15 Yeda Research And Development Co. Ltd. Poly-Glu,Tyr for neuroprotective therapy
US6835711B2 (en) * 2001-06-28 2004-12-28 Yeda Research And Development Co. Ltd. Use of poly-Glu,Tyr for neuroprotective therapy

Also Published As

Publication number Publication date
WO2003047500A2 (en) 2003-06-12
CA2469092C (en) 2013-02-19
EP1429800B1 (en) 2009-02-11
AU2002353486A1 (en) 2003-06-17
PT1429800E (pt) 2009-04-27
CN1617736A (zh) 2005-05-18
CY1109044T1 (el) 2014-07-02
AU2002353486B2 (en) 2009-01-15
PL370070A1 (en) 2005-05-16
JP4542339B2 (ja) 2010-09-15
HUP0500039A3 (en) 2010-01-28
KR20040081431A (ko) 2004-09-21
SI1429800T1 (sl) 2009-08-31
CA2469092A1 (en) 2003-06-12
WO2003047500A3 (en) 2004-03-18
CN102151330A (zh) 2011-08-17
IL160105A0 (en) 2004-06-20
US7351686B2 (en) 2008-04-01
MXPA04005537A (es) 2004-11-01
IS2670B (is) 2010-09-15
EP1429800A2 (en) 2004-06-23
US20050220802A1 (en) 2005-10-06
HU228207B1 (hu) 2013-01-28
JP2005515198A (ja) 2005-05-26
ES2322566T3 (es) 2009-06-23
NZ533356A (en) 2006-10-27
NO20042833L (no) 2004-08-12
HUP0500039A2 (hu) 2005-03-29
PL205469B1 (pl) 2010-04-30
CN102151330B (zh) 2017-04-12
EP1429800A4 (en) 2006-03-22
RU2004120536A (ru) 2005-03-27
DE60231131D1 (de) 2009-03-26
HK1067043A1 (en) 2005-04-01
DK1429800T3 (da) 2009-04-27
RU2303996C2 (ru) 2007-08-10
ATE422362T1 (de) 2009-02-15
IS7296A (is) 2004-06-03

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