DE60231131D1 - Vakzine und verwendung davon zur behandlung amyotrophischer lateralsklerose - Google Patents
Vakzine und verwendung davon zur behandlung amyotrophischer lateralskleroseInfo
- Publication number
- DE60231131D1 DE60231131D1 DE60231131T DE60231131T DE60231131D1 DE 60231131 D1 DE60231131 D1 DE 60231131D1 DE 60231131 T DE60231131 T DE 60231131T DE 60231131 T DE60231131 T DE 60231131T DE 60231131 D1 DE60231131 D1 DE 60231131D1
- Authority
- DE
- Germany
- Prior art keywords
- cop
- vaccine
- lateral sclerosis
- amyotrophic lateral
- treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0008—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0007—Nervous system antigens; Prions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Rheumatology (AREA)
- Ophthalmology & Optometry (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US33613901P | 2001-12-06 | 2001-12-06 | |
PCT/IL2002/000979 WO2003047500A2 (en) | 2001-12-06 | 2002-12-05 | Vaccine and method for treatment of motor neurone diseases |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60231131D1 true DE60231131D1 (de) | 2009-03-26 |
Family
ID=23314742
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60231131T Expired - Lifetime DE60231131D1 (de) | 2001-12-06 | 2002-12-05 | Vakzine und verwendung davon zur behandlung amyotrophischer lateralsklerose |
Country Status (24)
Country | Link |
---|---|
US (1) | US7351686B2 (de) |
EP (1) | EP1429800B1 (de) |
JP (1) | JP4542339B2 (de) |
KR (1) | KR20040081431A (de) |
CN (2) | CN102151330B (de) |
AT (1) | ATE422362T1 (de) |
AU (1) | AU2002353486B2 (de) |
CA (1) | CA2469092C (de) |
CY (1) | CY1109044T1 (de) |
DE (1) | DE60231131D1 (de) |
DK (1) | DK1429800T3 (de) |
ES (1) | ES2322566T3 (de) |
HK (1) | HK1067043A1 (de) |
HU (1) | HU228207B1 (de) |
IL (1) | IL160105A0 (de) |
IS (1) | IS2670B (de) |
MX (1) | MXPA04005537A (de) |
NO (1) | NO336231B1 (de) |
NZ (1) | NZ533356A (de) |
PL (1) | PL205469B1 (de) |
PT (1) | PT1429800E (de) |
RU (1) | RU2303996C2 (de) |
SI (1) | SI1429800T1 (de) |
WO (1) | WO2003047500A2 (de) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7399740B2 (en) | 2001-06-28 | 2008-07-15 | Yeda Research And Development Co. Ltd. | Poly-Glu,Tyr for neuroprotective therapy |
WO2004060265A2 (en) * | 2003-01-07 | 2004-07-22 | Yeda Research And Development Co. Ltd. | Eye-drop vaccine containing copolymer 1 for therapeutic immunization |
EP1684797A1 (de) | 2003-11-12 | 2006-08-02 | Yeda Research and Development Co. Ltd. | Vakzine und verfahren zur behandlung von neurodegenerativen erkrankungen |
DK1701730T3 (da) | 2003-12-09 | 2013-11-25 | Yeda Res & Dev | Fremgangsmåde og vaccine omfattende copolymer 1 til behandling af psykiatriske forstyrrelser |
AU2005218625A1 (en) * | 2004-03-03 | 2005-09-15 | Teva Pharmaceutical Industries, Ltd. | Combination therapy with glatiramer acetate and riluzole |
US7655221B2 (en) * | 2004-05-07 | 2010-02-02 | Peptimmune, Inc. | Methods of treating disease with random copolymers |
JP5495490B2 (ja) * | 2004-05-07 | 2014-05-21 | アレス トレーディング エスエイ | ランダム共重合体を用いる疾患の治療方法 |
CA2615506A1 (en) | 2005-07-15 | 2007-01-25 | Novartis Ag | Pamps, pathogen associated molecular patterns |
CN100448481C (zh) * | 2006-06-22 | 2009-01-07 | 中国科学院遗传与发育生物学研究所 | xCT蛋白及其编码基因的新用途 |
US8193147B2 (en) | 2007-09-24 | 2012-06-05 | Hadasit Medical Research Services & Development Ltd. | Use of copolymer 1 for treatment of muscular dystrophy |
USRE49251E1 (en) | 2010-01-04 | 2022-10-18 | Mapi Pharma Ltd. | Depot systems comprising glatiramer or pharmacologically acceptable salt thereof |
US8759302B2 (en) * | 2010-03-16 | 2014-06-24 | Teva Pharmaceutical Industries, Ltd. | Methods of treating a subject afflicted with an autoimmune disease using predictive biomarkers of clinical response to glatiramer acetate therapy in multiple sclerosis |
PL2627669T3 (pl) | 2010-10-11 | 2017-02-28 | Teva Pharmaceutical Industries Ltd. | Biomarkery cytokinowe jako biomarkery prognostyczne odpowiedzi klinicznej na octan glatirameru |
EP2699317B1 (de) | 2011-04-21 | 2016-08-10 | Mapi Pharma Limited | Zufallspentapolymer zur behandlung von autoimmunkrankheiten |
CN103957705A (zh) | 2011-10-10 | 2014-07-30 | 泰华制药工业有限公司 | 适用于预测对醋酸格拉替雷的临床反应的单核苷酸多态性 |
EP2788017B1 (de) * | 2011-12-05 | 2017-05-31 | Ben-Gurion University of The Negev Research and Development Authority | INHIBITOREN VON IgG-A2BG2 ZUR BEHANDLUNG UND DIAGNOSE VON AMYOTROPHISCHER LATERALSKLEROSE |
CA2907909A1 (en) * | 2012-03-26 | 2013-10-03 | Neuroquest Ltd. | Cellular markers for diagnosis of alzheimer's disease and for alzheimer's disease progression |
EP3320914B1 (de) | 2012-09-10 | 2020-12-30 | Yeda Research And Development Co. Ltd. At The Weizmann Institute Of Science | Th1-typ adjuvans zur behandlung von amyotropher lateralsklerose |
JP2020515530A (ja) | 2017-03-26 | 2020-05-28 | マピ ファーマ リミテッド | 進行型の多発性硬化症を治療するためのグラチラマーデポシステム |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL36670A (en) * | 1971-04-21 | 1974-09-10 | Sela M | Therapeutic basic copolymers of amino acids |
US3849650A (en) | 1973-03-29 | 1974-11-19 | Picker Corp | Automatic x-ray inspection system |
IL113812A (en) | 1994-05-24 | 2000-06-29 | Yeda Res & Dev | Copolymer-1 pharmaceutical compositions containing it and its use |
SE505316C2 (sv) | 1995-10-17 | 1997-08-04 | Kenneth G Haglid | Användning av proteinet S-100b för framställning av läkemedel för nervceller |
WO1999034827A1 (en) | 1998-07-21 | 1999-07-15 | Yeda Research And Development Co. Ltd. | Activated t-cells and their uses |
US20030108528A1 (en) | 1998-05-19 | 2003-06-12 | Michal Eisenbach-Schwartz | Activated t-cells, nervous system-specific antigens and their uses |
US20020072493A1 (en) | 1998-05-19 | 2002-06-13 | Yeda Research And Development Co. Ltd. | Activated T cells, nervous system-specific antigens and their uses |
CA2328612A1 (en) | 1998-05-19 | 1999-11-25 | Yeda Research And Development Co., Ltd. | Activated t cells, nervous system-specific antigens and their uses |
EP1105414A2 (de) | 1998-07-23 | 2001-06-13 | President And Fellows of Harvard College | Kunstliche peptide und deren verwendungen für therapie gegen autoimmunkrankenheiten |
US6844314B2 (en) * | 2000-01-20 | 2005-01-18 | Yeda Research Development Co., Ltd. | Use of copolymer 1 and related peptides and polypeptides and T cells treated therewith for neuroprotective therapy |
ATE314860T1 (de) | 2000-06-07 | 2006-02-15 | Yeda Res & Dev | Verwendung des copolymer-1 peptids sowie von damit verwandten peptiden und polypeptiden und von damit behandelten t-zellen zur neuroprotektion vor glutamattoxizitaet |
WO2002076503A1 (en) * | 2000-06-20 | 2002-10-03 | Mayo Foundation For Medical Education And Research | Treatment of central nervous system diseases by antibodies against glatiramer acetate |
US7399740B2 (en) * | 2001-06-28 | 2008-07-15 | Yeda Research And Development Co. Ltd. | Poly-Glu,Tyr for neuroprotective therapy |
US6835711B2 (en) * | 2001-06-28 | 2004-12-28 | Yeda Research And Development Co. Ltd. | Use of poly-Glu,Tyr for neuroprotective therapy |
-
2002
- 2002-12-05 WO PCT/IL2002/000979 patent/WO2003047500A2/en active Application Filing
- 2002-12-05 IL IL16010502A patent/IL160105A0/xx unknown
- 2002-12-05 CA CA2469092A patent/CA2469092C/en not_active Expired - Fee Related
- 2002-12-05 EP EP02788511A patent/EP1429800B1/de not_active Expired - Lifetime
- 2002-12-05 CN CN201110056639.8A patent/CN102151330B/zh not_active Expired - Fee Related
- 2002-12-05 PT PT02788511T patent/PT1429800E/pt unknown
- 2002-12-05 HU HU0500039A patent/HU228207B1/hu not_active IP Right Cessation
- 2002-12-05 MX MXPA04005537A patent/MXPA04005537A/es active IP Right Grant
- 2002-12-05 KR KR10-2004-7008780A patent/KR20040081431A/ko active Search and Examination
- 2002-12-05 DK DK02788511T patent/DK1429800T3/da active
- 2002-12-05 DE DE60231131T patent/DE60231131D1/de not_active Expired - Lifetime
- 2002-12-05 AU AU2002353486A patent/AU2002353486B2/en not_active Ceased
- 2002-12-05 ES ES02788511T patent/ES2322566T3/es not_active Expired - Lifetime
- 2002-12-05 JP JP2003548761A patent/JP4542339B2/ja not_active Expired - Fee Related
- 2002-12-05 AT AT02788511T patent/ATE422362T1/de active
- 2002-12-05 CN CNA028277015A patent/CN1617736A/zh active Pending
- 2002-12-05 SI SI200230800T patent/SI1429800T1/sl unknown
- 2002-12-05 US US10/485,576 patent/US7351686B2/en not_active Expired - Lifetime
- 2002-12-05 RU RU2004120536/14A patent/RU2303996C2/ru not_active IP Right Cessation
- 2002-12-05 PL PL370070A patent/PL205469B1/pl unknown
- 2002-12-05 NZ NZ533356A patent/NZ533356A/en not_active IP Right Cessation
-
2004
- 2004-06-03 IS IS7296A patent/IS2670B/is unknown
- 2004-07-05 NO NO20042833A patent/NO336231B1/no not_active IP Right Cessation
- 2004-12-16 HK HK04110020.9A patent/HK1067043A1/xx not_active IP Right Cessation
-
2009
- 2009-05-06 CY CY20091100485T patent/CY1109044T1/el unknown
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |