NO332691B1 - Kalsitonin-gen-relaterte peptid-reseptor-antagonister samt anvendelse av disse for fremstilling av et farmasoytisk preparat for behandling av migrene - Google Patents
Kalsitonin-gen-relaterte peptid-reseptor-antagonister samt anvendelse av disse for fremstilling av et farmasoytisk preparat for behandling av migrene Download PDFInfo
- Publication number
- NO332691B1 NO332691B1 NO20045219A NO20045219A NO332691B1 NO 332691 B1 NO332691 B1 NO 332691B1 NO 20045219 A NO20045219 A NO 20045219A NO 20045219 A NO20045219 A NO 20045219A NO 332691 B1 NO332691 B1 NO 332691B1
- Authority
- NO
- Norway
- Prior art keywords
- oxo
- dihydro
- indazol
- ylmethyl
- carboxylic acid
- Prior art date
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PCT/US2003/016576 WO2003104236A1 (en) | 2002-06-01 | 2003-05-27 | Calcitonin gene related peptide receptor antagonists |
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JP (1) | JP4490809B2 (pt) |
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HR (1) | HRP20041147A2 (pt) |
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WO (1) | WO2003104236A1 (pt) |
Families Citing this family (62)
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US7220862B2 (en) | 2002-06-05 | 2007-05-22 | Bristol-Myers Squibb Company | Calcitonin gene related peptide receptor antagonists |
US7595312B2 (en) | 2002-10-25 | 2009-09-29 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Selected CGRP antagonists, processes for preparing them and their use as pharmaceutical compositions |
DE10250082A1 (de) * | 2002-10-25 | 2004-05-13 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Ausgewählte CGRP-Antagonisten, Verfahren zu deren Herstellung sowie deren Verwendung als Arzneimittel |
DE10300973A1 (de) * | 2003-01-14 | 2004-07-22 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Carbonsäuren und deren Ester, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung |
JO2355B1 (en) * | 2003-04-15 | 2006-12-12 | ميرك شارب اند دوم كوربوريشن | Hereditary calcitonin polypeptide receptor antagonists |
US7989634B2 (en) * | 2003-11-12 | 2011-08-02 | Lg Life Sciences Ltd. | Melanocortin receptor agonists |
AR046787A1 (es) | 2003-12-05 | 2005-12-21 | Bristol Myers Squibb Co | Agentes antimigrana heterociclicos |
UA81563C2 (en) * | 2003-12-05 | 2008-01-10 | Bristol Myers Squibb Co | Antagonists of calcitonin gene-related peptide receptors |
CA2550012A1 (en) * | 2003-12-17 | 2005-06-30 | Takeda Pharmaceutical Company Limited | Urea derivative, process for producing the same and use |
WO2005084672A1 (de) * | 2004-03-03 | 2005-09-15 | Boehringer Ingelheim International Gmbh | Ausgewählte cgrp-antagonisten, verfahren zu deren herstellung sowie deren verwendung als arzneimittel |
EP1725564A4 (en) * | 2004-03-17 | 2007-09-12 | Glaxo Group Ltd | ANTAGONISTS OF THE M3 MUSCARIN ACETYL CHOLIN RECEPTOR |
AP2379A (en) | 2004-03-23 | 2012-03-08 | Pfizer Prod Inc | Imidazole compounds for the treatment of neurodegenerative disorders. |
DE102004015723A1 (de) * | 2004-03-29 | 2005-10-20 | Boehringer Ingelheim Pharma | Ausgewählte CGRP-Antagonisten, Verfahren zu deren Herstellung sowie deren Verwendung als Arzneimittel |
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US7547694B2 (en) * | 2004-04-15 | 2009-06-16 | Boehringer Ingelheim International Gmbh | Selected CGRP-antagonists, process for preparing them and their use as pharmaceutical compositions |
DE102004018795A1 (de) * | 2004-04-15 | 2005-10-27 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Ausgewählte CGRP-Antagonisten, Verfahren zu deren Herstellung sowie deren Verwendung als Arzneimittel |
DE102004018794A1 (de) * | 2004-04-15 | 2005-10-27 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Ausgewählte CGRP-Antagonisten, Verfahren zu deren Herstellung sowie deren Verwendung als Arzneimittel |
US7279471B2 (en) | 2004-04-15 | 2007-10-09 | Boehringer Ingelheim International Gmbh | Selected CGRP-antagonists, process for preparing them and their use as pharmaceutical compositions |
CN101014345A (zh) * | 2004-09-09 | 2007-08-08 | 默克公司 | 三环酰苯胺螺环内酰胺cgrp受体拮抗剂 |
CA2580020A1 (en) * | 2004-09-09 | 2006-03-23 | Ian M. Bell | Aryl spirolactam cgrp receptor antagonists |
AU2005285083B2 (en) * | 2004-09-13 | 2011-03-10 | Merck Sharp & Dohme Corp. | Tricyclic anilide spirohydantoin CGRP receptor antagonists |
CA2582593A1 (en) * | 2004-10-07 | 2006-04-20 | Merck & Co., Inc. | Cgrp receptor antagonists |
KR20070062997A (ko) * | 2004-10-13 | 2007-06-18 | 머크 앤드 캄파니 인코포레이티드 | Cgrp 수용체 길항제 |
ATE507880T1 (de) * | 2004-10-14 | 2011-05-15 | Merck Sharp & Dohme | Cgrp-rezeptorantagonisten |
CA2584241A1 (en) * | 2004-10-22 | 2006-05-04 | Merck & Co., Inc. | Cgrp receptor antagonists |
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AU2008313733A1 (en) | 2007-10-18 | 2009-04-23 | Boehringer Ingelheim International Gmbh | CGRP antagonists |
EP2062889A1 (de) | 2007-11-22 | 2009-05-27 | Boehringer Ingelheim Pharma GmbH & Co. KG | Verbindungen |
RU2522493C2 (ru) | 2008-03-04 | 2014-07-20 | Пфайзер Лимитед | Способы лечения хронической боли |
US8623366B2 (en) | 2009-08-28 | 2014-01-07 | Labrys Biologics, Inc. | Methods for treating visceral pain by administering antagonist antibodies directed against calcitonin gene-related peptide |
US8481546B2 (en) * | 2010-03-30 | 2013-07-09 | Bristol-Myers Squibb Company | CGRP receptor antagonist |
HUE054437T2 (hu) | 2011-05-20 | 2021-09-28 | H Lundbeck As | Anti-CGRP készítmények és alkalmazásuk |
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