NO330978B1 - Fremgangsmate for a fremstille optisk rene PPI som har en sulfinylstruktur - Google Patents

Fremgangsmate for a fremstille optisk rene PPI som har en sulfinylstruktur

Info

Publication number
NO330978B1
NO330978B1 NO20053099A NO20053099A NO330978B1 NO 330978 B1 NO330978 B1 NO 330978B1 NO 20053099 A NO20053099 A NO 20053099A NO 20053099 A NO20053099 A NO 20053099A NO 330978 B1 NO330978 B1 NO 330978B1
Authority
NO
Norway
Prior art keywords
optically pure
producing optically
ppi
sulfinyl structure
sulfinyl
Prior art date
Application number
NO20053099A
Other languages
English (en)
Norwegian (no)
Other versions
NO20053099L (no
NO20053099D0 (no
Inventor
Bernhard Kohl
Bernd Mueller
Ralf Steffen Weingart
Original Assignee
Nycomed Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed Gmbh filed Critical Nycomed Gmbh
Publication of NO20053099L publication Critical patent/NO20053099L/no
Publication of NO20053099D0 publication Critical patent/NO20053099D0/no
Publication of NO330978B1 publication Critical patent/NO330978B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Catalysts (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pyrrole Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
NO20053099A 2002-12-06 2005-06-24 Fremgangsmate for a fremstille optisk rene PPI som har en sulfinylstruktur NO330978B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP02027273 2002-12-06
DE10340255 2003-08-29
PCT/EP2003/013605 WO2004052882A1 (en) 2002-12-06 2003-12-03 Process for preparing optically pure active compounds

Publications (3)

Publication Number Publication Date
NO20053099L NO20053099L (no) 2005-06-24
NO20053099D0 NO20053099D0 (no) 2005-06-24
NO330978B1 true NO330978B1 (no) 2011-08-29

Family

ID=32509784

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20053099A NO330978B1 (no) 2002-12-06 2005-06-24 Fremgangsmate for a fremstille optisk rene PPI som har en sulfinylstruktur

Country Status (28)

Country Link
US (1) US7452998B2 (ru)
EP (1) EP1578742B1 (ru)
JP (1) JP4612542B2 (ru)
KR (1) KR101062806B1 (ru)
CN (1) CN100482658C (ru)
AR (1) AR042277A1 (ru)
AU (1) AU2003289948B2 (ru)
BR (2) BRPI0310118B1 (ru)
CA (1) CA2507807C (ru)
CY (1) CY1114058T1 (ru)
DK (1) DK1578742T3 (ru)
EA (1) EA011771B1 (ru)
ES (1) ES2397380T3 (ru)
HK (1) HK1078864A1 (ru)
HR (1) HRP20050604B1 (ru)
IL (1) IL168456A (ru)
IS (1) IS2885B (ru)
ME (1) ME00563A (ru)
MX (1) MXPA05005762A (ru)
NO (1) NO330978B1 (ru)
NZ (1) NZ540815A (ru)
PL (1) PL375818A1 (ru)
PT (1) PT1578742E (ru)
RS (1) RS52667B (ru)
SI (1) SI1578742T1 (ru)
TW (1) TWI313268B (ru)
WO (1) WO2004052882A1 (ru)
ZA (1) ZA200503543B (ru)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL144144A0 (en) 1999-01-13 2002-05-23 Bayer Ag Omega-carboxy aryl substituted diphenyl ureas as p38 kinase inhibitors
EP1575941B1 (en) 2002-12-06 2012-04-11 Nycomed GmbH Process for preparing (S)-pantoprazole
FR2848555B1 (fr) * 2002-12-16 2006-07-28 Negma Gild Enantiomere(-)du tenatoprazole et son application en therapeutique
CA2510849A1 (en) * 2002-12-19 2004-07-08 Teva Pharmaceutical Industries Ltd Solid states of pantoprazole sodium, processes for preparing them and processes for preparing known pantoprazole sodium hydrates
US7683177B2 (en) * 2003-06-10 2010-03-23 Teva Pharmaceutical Industries Ltd Process for preparing 2-[(pyridinyl)methyl]sulfinyl-substituted benzimidazoles and novel chlorinated derivatives of pantoprazole
CA2568652A1 (en) * 2004-06-02 2005-12-15 Altana Pharma Ag Process for the preparation of pyridin-2-ylmethylsulphinyl-1h-benzimidazol compounds
FR2871800B1 (fr) * 2004-06-17 2006-08-25 Sidem Pharma Sa Sa Sel de sodium monohydrate du s-tenatoprazole et application en therapeutique
NZ551970A (en) * 2004-06-24 2010-01-29 Astrazeneca Ab New process for the preparation of crystal modifications for use in the preparation of esomeprazole sodium salt
EP1801110A1 (en) 2005-12-22 2007-06-27 KRKA, tovarna zdravil, d.d., Novo mesto Esomeprazole arginine salt
US7579476B2 (en) * 2006-02-24 2009-08-25 Praktikatalyst Pharma, Llc Transition metal mediated oxidation of hetero atoms in organic molecules coordinated to transition metals
US8173818B2 (en) 2006-08-08 2012-05-08 Jubilant Organosys Limited Process for producing sulphoxide compounds
WO2008047681A1 (fr) 2006-10-13 2008-04-24 Eisai R & D Management Co., Ltd. Benzimidazole présentant une activité inhibitrice de la sécrétion d'acide gastrique
US20080103169A1 (en) 2006-10-27 2008-05-01 The Curators Of The University Of Missouri Compositions comprising acid labile proton pump inhibiting agents, at least one other pharmaceutically active agent and methods of using same
US20110028518A1 (en) * 2008-03-18 2011-02-03 Dr. Reddy's Laboratories Ltd. Dexlansoprazole process and polymorphs
EP2143722A1 (en) 2008-07-09 2010-01-13 Lek Pharmaceuticals D.D. Process for preparation of esomeprazole sodium of high chemical purity and new forms of esomeprazole sodium
EP2264024A1 (en) 2008-10-14 2010-12-22 LEK Pharmaceuticals d.d. Process for the preparation of enantiomerically enriched proton pump inhibitors
US8071781B2 (en) 2008-11-11 2011-12-06 Syn-Tech Chem. & Pharm. Co., Ltd. Process for preparing rabeprazole sodium
ES2523921T3 (es) 2010-02-12 2014-12-02 Esteve Química, S.A. Procedimiento de preparación de la sal sódica de esomeprazol
CN103113351B (zh) * 2013-03-08 2015-01-21 苏州特瑞药业有限公司 一种光学纯手性亚砜类化合物的制备方法
CN103936714A (zh) * 2014-04-15 2014-07-23 北京华禧联合科技发展有限公司 一种埃索美拉唑镁的制备方法
CN107428726B (zh) 2014-12-26 2021-03-16 国立大学法人东京大学 光学活性的质子泵抑制剂化合物的制备方法
CN105440018A (zh) * 2015-11-27 2016-03-30 福州闽海药业有限公司 一种锆催化的右旋兰索拉唑的不对称氧化合成方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE7804231L (sv) 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
IL75400A (en) 1984-06-16 1988-10-31 Byk Gulden Lomberg Chem Fab Dialkoxypyridine methyl(sulfinyl or sulfonyl)benzimidazoles,processes for the preparation thereof and pharmaceutical compositions containing the same
JPS6150978A (ja) 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
FI90544C (fi) 1986-11-13 1994-02-25 Eisai Co Ltd Menetelmä lääkeaineina käyttökelpoisten 2-pyridin-2-yyli-metyylitio- ja sulfinyyli-1H-bensimidatsolijohdannaisten valmistamiseksi
SE465514B (sv) 1990-02-19 1991-09-23 Curt Pettersson Foerfarande och anvaendning av ett separationsmedium vid separation av enantiomerer
DE4035455A1 (de) 1990-11-08 1992-05-14 Byk Gulden Lomberg Chem Fab Enantiomerentrennung
CA2161130A1 (en) 1993-04-27 1994-11-10 Nancy M. Gray Methods and compositions for treating gastric disorders using optically pure (+) pantoprazole
CA2161256C (en) 1993-04-27 2004-06-29 Nancy M. Gray Methods and compositions for treating gastric disorders using optically pure (-) pantoprazole
SE9301830D0 (sv) 1993-05-28 1993-05-28 Ab Astra New compounds
SE504459C2 (sv) * 1994-07-15 1997-02-17 Astra Ab Förfarande för framställning av substituerade sulfoxider
GB9423970D0 (en) 1994-11-28 1995-01-11 Astra Ab Oxidation
GB9423968D0 (en) 1994-11-28 1995-01-11 Astra Ab Resolution
HRP960232A2 (en) 1995-07-03 1998-02-28 Astra Ab A process for the optical purification of compounds
EP1575941B1 (en) 2002-12-06 2012-04-11 Nycomed GmbH Process for preparing (S)-pantoprazole

Also Published As

Publication number Publication date
CA2507807C (en) 2013-10-22
EA011771B1 (ru) 2009-06-30
EA200500898A1 (ru) 2005-12-29
HRP20050604B1 (hr) 2013-09-30
BRPI0310118B1 (pt) 2015-10-20
ZA200503543B (en) 2006-08-30
AU2003289948A1 (en) 2004-06-30
JP2006516261A (ja) 2006-06-29
CY1114058T1 (el) 2016-07-27
TW200508219A (en) 2005-03-01
RS52667B (en) 2013-06-28
JP4612542B2 (ja) 2011-01-12
EP1578742A1 (en) 2005-09-28
RS20050423A (en) 2007-04-10
WO2004052882A1 (en) 2004-06-24
IS2885B (is) 2014-07-15
NO20053099L (no) 2005-06-24
US20050288334A1 (en) 2005-12-29
BR0317005A (pt) 2005-10-25
PL375818A1 (en) 2005-12-12
US7452998B2 (en) 2008-11-18
IS7909A (is) 2005-06-23
HK1078864A1 (en) 2006-03-24
ME00563A (en) 2011-12-20
AR042277A1 (es) 2005-06-15
PT1578742E (pt) 2013-01-24
ES2397380T3 (es) 2013-03-06
HRP20050604A2 (en) 2006-09-30
MXPA05005762A (es) 2005-08-16
EP1578742B1 (en) 2012-10-17
NO20053099D0 (no) 2005-06-24
IL168456A (en) 2012-02-29
SI1578742T1 (sl) 2013-02-28
KR20050085224A (ko) 2005-08-29
DK1578742T3 (da) 2013-01-21
CN100482658C (zh) 2009-04-29
CA2507807A1 (en) 2004-06-24
AU2003289948B2 (en) 2009-12-24
KR101062806B1 (ko) 2011-09-07
NZ540815A (en) 2008-03-28
CN1717403A (zh) 2006-01-04
TWI313268B (en) 2009-08-11

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Legal Events

Date Code Title Description
CREP Change of representative

Representative=s name: PLOUGMANN & VINGTOFT, POSTBOKS 1003 SENTRUM, 0104

CHAD Change of the owner's name or address (par. 44 patent law, par. patentforskriften)

Owner name: TAKEDA GMBH, DE

MM1K Lapsed by not paying the annual fees