NO330459B1 - Anvendelse av zoledronsyre for behandling av tilstander med okt benomsetning - Google Patents
Anvendelse av zoledronsyre for behandling av tilstander med okt benomsetning Download PDFInfo
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- NO330459B1 NO330459B1 NO20026117A NO20026117A NO330459B1 NO 330459 B1 NO330459 B1 NO 330459B1 NO 20026117 A NO20026117 A NO 20026117A NO 20026117 A NO20026117 A NO 20026117A NO 330459 B1 NO330459 B1 NO 330459B1
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- Prior art keywords
- zoledronic acid
- treatment
- bone
- pharmaceutically acceptable
- period
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- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
- A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Physical Education & Sports Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US59713500A | 2000-06-20 | 2000-06-20 | |
| US26768901P | 2001-02-09 | 2001-02-09 | |
| PCT/EP2001/006850 WO2001097788A2 (en) | 2000-06-20 | 2001-06-18 | Method of administering bisphosphonates |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO20026117D0 NO20026117D0 (no) | 2002-12-19 |
| NO20026117L NO20026117L (no) | 2002-12-19 |
| NO330459B1 true NO330459B1 (no) | 2011-04-18 |
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| NO20026117A NO330459B1 (no) | 2000-06-20 | 2002-12-19 | Anvendelse av zoledronsyre for behandling av tilstander med okt benomsetning |
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| US (1) | US8052987B2 (cs) |
| EP (1) | EP1296689B3 (cs) |
| JP (2) | JP4722375B2 (cs) |
| KR (1) | KR100864743B1 (cs) |
| CN (1) | CN1272013C (cs) |
| AT (1) | ATE304856T1 (cs) |
| AU (2) | AU2001274109B2 (cs) |
| BR (1) | BR0111806A (cs) |
| CA (1) | CA2410201C (cs) |
| CY (2) | CY1113740T1 (cs) |
| CZ (1) | CZ301972B6 (cs) |
| DE (1) | DE60113537T3 (cs) |
| DK (1) | DK1296689T3 (cs) |
| ES (2) | ES2394211T3 (cs) |
| HU (1) | HU228400B1 (cs) |
| IL (2) | IL153229A0 (cs) |
| MX (1) | MXPA02012682A (cs) |
| NO (1) | NO330459B1 (cs) |
| NZ (1) | NZ523086A (cs) |
| PL (1) | PL203087B1 (cs) |
| PT (1) | PT1591122E (cs) |
| SK (1) | SK287278B6 (cs) |
| TW (1) | TWI289451B (cs) |
| WO (1) | WO2001097788A2 (cs) |
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| US20070148228A1 (en) * | 1999-02-22 | 2007-06-28 | Merrion Research I Limited | Solid oral dosage form containing an enhancer |
| US7658938B2 (en) | 1999-02-22 | 2010-02-09 | Merrion Reasearch III Limited | Solid oral dosage form containing an enhancer |
| US8119159B2 (en) * | 1999-02-22 | 2012-02-21 | Merrion Research Iii Limited | Solid oral dosage form containing an enhancer |
| US8052987B2 (en) | 2000-06-20 | 2011-11-08 | Novartis Pharmaceuticals Corporation | Method of administering bisphosphonates |
| EP1192945A3 (en) * | 2000-09-21 | 2004-03-03 | Pfizer Products Inc. | Use of an estrogen agonist/antagonist for treating osteoarthritis |
| WO2002080933A1 (en) * | 2001-04-03 | 2002-10-17 | The Royal Alexandra Hospital For Children | A drug for use in bone grafting |
| US20050070504A1 (en) * | 2001-12-21 | 2005-03-31 | The Procter & Gamble Co. | Risedronate compositions and their methods of use |
| GB0204756D0 (en) * | 2002-02-28 | 2002-04-17 | Novartis Ag | Organic compounds |
| KR20140021045A (ko) * | 2002-05-10 | 2014-02-19 | 에프. 호프만-라 로슈 아게 | 골다공증 치료 및 예방용 비스포스폰산 |
| PT1542700E (pt) * | 2002-09-16 | 2012-02-01 | Novartis Ag | Método para prevenir ou reduzir fracturas secundárias após a fractura da anca |
| WO2004035061A1 (en) * | 2002-10-15 | 2004-04-29 | Novartis Ag | Method of administering bisphosphonates |
| NZ536273A (en) | 2002-12-20 | 2007-08-31 | Hoffmann La Roche | High dose ibandronate formulation |
| EP1709968A1 (en) * | 2004-01-30 | 2006-10-11 | Astellas Pharma Inc. | P2x receptor inhibitor |
| ATE495747T1 (de) * | 2004-08-23 | 2011-02-15 | Teva Pharma | Kristalline form des ibandronat-natriums und herstellungsverfahren dafür |
| CN101087606B (zh) * | 2004-12-09 | 2010-12-29 | 默沙东公司 | 雌激素受体调节剂 |
| US7709508B2 (en) | 2004-12-09 | 2010-05-04 | Merck Sharp & Dohme | Estrogen receptor modulators |
| US8071574B2 (en) * | 2005-02-22 | 2011-12-06 | John Dennis Bobyn | Implant improving local bone formation |
| US7473684B2 (en) * | 2005-09-16 | 2009-01-06 | Selamine Limited | Bisphosphonate formulation |
| CA2648594C (en) * | 2006-04-07 | 2012-10-16 | Merrion Research Iii Limited | Solid oral dosage form containing an enhancer |
| WO2007124274A1 (en) * | 2006-04-21 | 2007-11-01 | The Uab Research Foundation | Treating neoplasms |
| US20080139514A1 (en) * | 2006-11-29 | 2008-06-12 | Subhash Pandurang Gore | Diphosphonic acid pharmaceutical compositions |
| US20100068211A1 (en) * | 2008-02-08 | 2010-03-18 | Bateman Ted A | Use of antiresorptive compounds to prevent ionizing radiation-induced activation of osteoclasts and resulting bone loss |
| CN107096012A (zh) * | 2008-05-07 | 2017-08-29 | 诺和诺德股份有限公司 | 肽的组合物及其制备方法 |
| CA2751854A1 (en) * | 2009-02-25 | 2010-09-02 | Merrion Research Iii Limited | Composition and drug delivery of bisphosphonates |
| US8399023B2 (en) | 2009-07-31 | 2013-03-19 | Thar Pharmaceuticals, Inc. | Crystallization method and bioavailability |
| US9169279B2 (en) | 2009-07-31 | 2015-10-27 | Thar Pharmaceuticals, Inc. | Crystallization method and bioavailability |
| US20160016982A1 (en) | 2009-07-31 | 2016-01-21 | Thar Pharmaceuticals, Inc. | Crystallization method and bioavailability |
| CN105920023A (zh) | 2009-09-01 | 2016-09-07 | 杜克大学 | 双膦酸类组合物及其治疗心力衰竭的方法 |
| US20110182985A1 (en) * | 2010-01-28 | 2011-07-28 | Coughlan David C | Solid Pharmaceutical Composition with Enhancers and Methods of Preparing thereof |
| US9089484B2 (en) * | 2010-03-26 | 2015-07-28 | Merrion Research Iii Limited | Pharmaceutical compositions of selective factor Xa inhibitors for oral administration |
| US9340565B2 (en) | 2010-11-24 | 2016-05-17 | Thar Pharmaceuticals, Inc. | Crystalline forms |
| CN103476419A (zh) | 2011-01-07 | 2013-12-25 | 梅里翁第三研究有限公司 | 口服投药的含铁药物组合物 |
| EP2780021A4 (en) | 2011-11-16 | 2015-08-05 | Univ Duke | BISPHOSPHONATE COMPOSITIONS AND METHODS FOR TREATING AND / OR REDUCING HEART FAILURE |
| CN103623465B (zh) * | 2013-11-21 | 2015-12-30 | 彭江 | 一种可局部调节成破骨活性的组织工程骨支架及制备方法 |
| ES2975708T3 (es) | 2015-01-29 | 2024-07-12 | Novo Nordisk As | Comprimidos que comprenden agonista del GLP-1 y recubrimiento entérico |
| WO2017208070A1 (en) | 2016-05-31 | 2017-12-07 | Grünenthal GmbH | Bisphosphonic acid and coformers with lysin, glycin, nicotinamide for treating psoriatic arthritis |
| KR20180115979A (ko) | 2017-04-14 | 2018-10-24 | 연세대학교 산학협력단 | 비스포스포네이트를 포함하는 만성 이식신 기능부전 예방 또는 치료용 조성물 |
| GB201716716D0 (en) | 2017-10-12 | 2017-11-29 | Univ Of Hertfordshire Higher Education Corporation | Method for coating particles |
| US20210369769A1 (en) * | 2018-11-02 | 2021-12-02 | Dyve Biosciences, Inc. | Management of risk of cation overload and electrolyte imbalance with topically applied buffers |
| KR102049233B1 (ko) * | 2019-01-14 | 2019-11-28 | 연세대학교 산학협력단 | 비스포스포네이트를 포함하는 만성 이식신 기능부전 예방 또는 치료용 조성물 |
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| DE3587956T2 (de) | 1984-04-30 | 1995-05-24 | Procter & Gamble | Ausrüstung für die Verwendung bei der Behandlung von Osteoporose. |
| US4812311A (en) | 1984-12-21 | 1989-03-14 | The Procter & Gamble Company | Kit for use in the treatment of osteoporosis |
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| US4822609A (en) | 1984-12-21 | 1989-04-18 | The Procter & Gamble Company | Treatment of osteoporosis |
| US4761406A (en) | 1985-06-06 | 1988-08-02 | The Procter & Gamble Company | Regimen for treating osteoporosis |
| ATE72816T1 (de) | 1986-11-21 | 1992-03-15 | Ciba Geigy Ag | Neue substituierte alkandiphosphonsaeuren. |
| HUT68010A (en) | 1991-12-17 | 1995-05-29 | Procter & Gamble Pharma | The use of bisphonates and parathyroid hormone for the treatment of osteoporosis |
| WO1994000129A1 (en) | 1992-06-30 | 1994-01-06 | Procter & Gamble Pharmaceuticals, Inc. | Use of phosphonates for the treatment of osteoporosis |
| AU670337B2 (en) | 1992-11-30 | 1996-07-11 | Novartis Ag | Use of certain methanebisphosphonic acid derivatives in fracture healing |
| EP0600834A1 (en) | 1992-11-30 | 1994-06-08 | Ciba-Geigy Ag | Use of methanebisphosphonic acid derivatives for the manufacture of a medicament for fracture healing |
| US5366965A (en) | 1993-01-29 | 1994-11-22 | Boehringer Mannheim Gmbh | Regimen for treatment or prophylaxis of osteoporosis |
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| CA2199252A1 (en) | 1994-09-09 | 1996-03-14 | Ann Dunbar Geddes | Methods for the treatment of osteoporosis using bone active phosphonates and parathyroid hormone |
| AU686019B2 (en) | 1994-09-09 | 1998-01-29 | Procter & Gamble Company, The | Phosphonates and parathyroid hormone for osteoporosis |
| WO1997012619A1 (en) | 1995-09-29 | 1997-04-10 | Novartis Ag | Method of treating the navicular disease in horses |
| US5735810A (en) | 1996-06-14 | 1998-04-07 | Becton Dickinson And Company | Device for the iontophoretic administration of bisphosphonates |
| US5730715A (en) | 1996-06-14 | 1998-03-24 | Becton Dickinson And Company | Method for the iontophoretic administration of bisphosphonates |
| SE9702401D0 (sv) | 1997-06-19 | 1997-06-19 | Astra Ab | Pharmaceutical use |
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2001
- 2001-06-18 US US10/311,942 patent/US8052987B2/en not_active Expired - Lifetime
- 2001-06-18 EP EP01940580A patent/EP1296689B3/en not_active Expired - Lifetime
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- 2001-06-18 AU AU2001274109A patent/AU2001274109B2/en not_active Expired
- 2001-06-18 MX MXPA02012682A patent/MXPA02012682A/es active IP Right Grant
- 2001-06-18 CN CNB018113680A patent/CN1272013C/zh not_active Ceased
- 2001-06-18 PT PT50127117T patent/PT1591122E/pt unknown
- 2001-06-18 CZ CZ20024134A patent/CZ301972B6/cs not_active IP Right Cessation
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- 2001-06-18 HU HU0301164A patent/HU228400B1/hu active Protection Beyond IP Right Term
- 2001-06-18 KR KR1020027017283A patent/KR100864743B1/ko not_active Expired - Lifetime
- 2001-06-18 WO PCT/EP2001/006850 patent/WO2001097788A2/en not_active Ceased
- 2001-06-18 IL IL15322901A patent/IL153229A0/xx active IP Right Review Request
- 2001-06-18 ES ES01940580T patent/ES2247123T7/es active Active
- 2001-06-18 DK DK01940580T patent/DK1296689T3/da active
- 2001-06-18 NZ NZ523086A patent/NZ523086A/en not_active IP Right Cessation
- 2001-06-18 BR BR0111806-4A patent/BR0111806A/pt not_active Application Discontinuation
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- 2001-06-18 JP JP2002503265A patent/JP4722375B2/ja not_active Expired - Lifetime
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- 2001-06-20 TW TW090114964A patent/TWI289451B/zh not_active IP Right Cessation
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2002
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- 2002-12-19 NO NO20026117A patent/NO330459B1/no not_active IP Right Cessation
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