NO330254B1 - Krystallinsk 2,5-dion-3-(1-metyl-lH-indol-3-yl)-4-[1-(pyridin-2-ylmetyl)piperidin-4-yl]-1H-indol-3-yl]-1H-pyrrol monohydroklorid, anvendelse derav og farmasoytisk sammensetning innholdende nevnte monohydroklorid. - Google Patents
Krystallinsk 2,5-dion-3-(1-metyl-lH-indol-3-yl)-4-[1-(pyridin-2-ylmetyl)piperidin-4-yl]-1H-indol-3-yl]-1H-pyrrol monohydroklorid, anvendelse derav og farmasoytisk sammensetning innholdende nevnte monohydroklorid. Download PDFInfo
- Publication number
- NO330254B1 NO330254B1 NO20050676A NO20050676A NO330254B1 NO 330254 B1 NO330254 B1 NO 330254B1 NO 20050676 A NO20050676 A NO 20050676A NO 20050676 A NO20050676 A NO 20050676A NO 330254 B1 NO330254 B1 NO 330254B1
- Authority
- NO
- Norway
- Prior art keywords
- indol
- crystalline
- monohydrochloride
- salt
- methyl
- Prior art date
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
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|---|---|---|---|
| US39597602P | 2002-07-12 | 2002-07-12 | |
| PCT/US2003/019548 WO2004006928A1 (en) | 2002-07-12 | 2003-07-08 | Crystalline 2,5-dione-3-(1-methyl-1h-indol-3-yl)-4-[1-(pyridin-2-ylmethyl)piperidin-4-yl]-1h-indol-3-yl]-1h-pyrrole mono-hydrochloride |
Publications (2)
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| NO20050676L NO20050676L (no) | 2005-02-09 |
| NO330254B1 true NO330254B1 (no) | 2011-03-14 |
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| NO20050676A NO330254B1 (no) | 2002-07-12 | 2005-02-09 | Krystallinsk 2,5-dion-3-(1-metyl-lH-indol-3-yl)-4-[1-(pyridin-2-ylmetyl)piperidin-4-yl]-1H-indol-3-yl]-1H-pyrrol monohydroklorid, anvendelse derav og farmasoytisk sammensetning innholdende nevnte monohydroklorid. |
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| US (2) | US8114901B2 (de) |
| EP (1) | EP1523313B1 (de) |
| JP (2) | JP4771356B2 (de) |
| KR (1) | KR100687165B1 (de) |
| CN (1) | CN100430058C (de) |
| AU (1) | AU2003280958B9 (de) |
| CA (1) | CA2393720C (de) |
| DE (1) | DE60317675T2 (de) |
| EA (1) | EA007463B1 (de) |
| EC (1) | ECSP055537A (de) |
| ES (1) | ES2295605T3 (de) |
| HK (1) | HK1075839A1 (de) |
| HR (1) | HRP20050035B1 (de) |
| IL (1) | IL165747A (de) |
| NO (1) | NO330254B1 (de) |
| NZ (1) | NZ537137A (de) |
| PE (1) | PE20040652A1 (de) |
| PL (1) | PL373046A1 (de) |
| TW (1) | TWI315667B (de) |
| UA (1) | UA78801C2 (de) |
| WO (1) | WO2004006928A1 (de) |
| ZA (1) | ZA200500065B (de) |
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| AU2006207321B2 (en) | 2005-01-21 | 2012-09-06 | Astex Therapeutics Limited | Pharmaceutical compounds |
| EP2073807A1 (de) | 2006-10-12 | 2009-07-01 | Astex Therapeutics Limited | Pharmazeutische kombinationen |
| US8916552B2 (en) | 2006-10-12 | 2014-12-23 | Astex Therapeutics Limited | Pharmaceutical combinations |
| CN104434136A (zh) | 2009-03-02 | 2015-03-25 | 第七感生物系统有限公司 | 用于抽出血液的装置 |
| WO2011094573A1 (en) | 2010-01-28 | 2011-08-04 | Seventh Sense Biosystems, Inc. | Monitoring or feedback systems and methods |
| WO2011163347A2 (en) | 2010-06-23 | 2011-12-29 | Seventh Sense Biosystems, Inc. | Sampling devices and methods involving relatively little pain |
| EP2593014B1 (de) | 2010-07-16 | 2015-11-04 | Seventh Sense Biosystems, Inc. | Niederdruckumgebung für flüssigkeitstransfervorrichtungen |
| JP2013540764A (ja) * | 2010-09-30 | 2013-11-07 | ウイスコンシン アラムニ リサーチ ファンデーション | 結晶形の（２０Ｒ，２５Ｓ）−２−メチレン−１９，２６−ジノル−１α，２５−ジヒドロキシビタミンＤ３ |
| WO2012064802A1 (en) | 2010-11-09 | 2012-05-18 | Seventh Sense Biosystems, Inc. | Systems and interfaces for blood sampling |
| EP3106092A3 (de) | 2011-04-29 | 2017-03-08 | Seventh Sense Biosystems, Inc. | Systeme und verfahren zur flüssigkeitsentnahme aus einer person |
| EP3087919B2 (de) | 2011-04-29 | 2022-04-13 | Seventh Sense Biosystems, Inc. | Aufnahme von flüssigkeiten |
| AU2017285384A1 (en) | 2016-06-17 | 2019-02-07 | Cells For Cells, S.P.A. | Gelatin polymer derived from natural sources of cold-adapted marine species and uses thereof |
| EP3496722A1 (de) | 2016-08-10 | 2019-06-19 | H. Hoffnabb-La Roche Ag | Pharmazeutische zusammensetzungen mit akt-proteinkinasehemmern |
| JOP20190025A1 (ar) | 2016-09-01 | 2019-02-19 | Denovo Biopharma Llc | طرق وتركيبة لتوقع نشاط إنزاستورين |
| CN116199590A (zh) * | 2022-12-26 | 2023-06-02 | 湖北美林药业有限公司 | 一种盐酸多巴酚丁胺及其注射剂 |
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| DE3625738A1 (de) * | 1986-07-30 | 1988-02-11 | Goedecke Ag | 2-acyloxypropylamin-derivate, verfahren zu deren herstellung und deren verwendung |
| US4785085A (en) * | 1986-11-21 | 1988-11-15 | Bristol-Myers Company | Rebeccamycin analogs |
| US4808613A (en) * | 1986-11-21 | 1989-02-28 | Bristol-Myers Company | Rebeccamycin derivative containing pharmaceutical composition |
| US4923986A (en) * | 1987-03-09 | 1990-05-08 | Kyowa Hakko Kogyo Co., Ltd. | Derivatives of physiologically active substance K-252 |
| DE3803620A1 (de) | 1988-02-06 | 1989-08-17 | Goedecke Ag | Indolocarbazol-derivate, verfahren zu deren herstellung und diese enthaltende arzneimittel |
| SK278989B6 (sk) * | 1988-02-10 | 1998-05-06 | F. Hoffmann-La Roche Ag | Substituované pyroly, ich použitie na výrobu lieči |
| GB8904161D0 (en) * | 1989-02-23 | 1989-04-05 | Hoffmann La Roche | Substituted pyrroles |
| US5380746A (en) * | 1989-05-05 | 1995-01-10 | Goedecke Aktiengesellschaft | Bis-(1H-indol-3-YL)-maleinimide derivatives, processes for the preparation thereof and pharmaceutical compositions containing them |
| CA2015996C (en) | 1989-05-05 | 2001-08-28 | Hartmut Osswald | Bis-(1h-indol-3-yl)-maleinimide derivatives and their use as pharmaceuticals |
| US5489608A (en) * | 1989-12-21 | 1996-02-06 | Goedecke Aktiengesellschaft | Indolocarbazole derivatives and the use thereof |
| DE4005969A1 (de) | 1990-02-26 | 1991-08-29 | Boehringer Mannheim Gmbh | Neue trisubstituierte pyrrole, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten |
| DE4005970A1 (de) | 1990-02-26 | 1991-08-29 | Boehringer Mannheim Gmbh | Neue trisubstituierte maleinimide, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten |
| CA2046801C (en) | 1990-08-07 | 2002-02-26 | Peter D. Davis | Substituted pyrroles |
| US5292747A (en) * | 1990-08-07 | 1994-03-08 | Hoffman-La Roche Inc. | Substituted pyrroles |
| GB9123396D0 (en) | 1991-11-04 | 1991-12-18 | Hoffmann La Roche | A process for the manufacture of substituted maleimides |
| US5461146A (en) | 1992-07-24 | 1995-10-24 | Cephalon, Inc. | Selected protein kinase inhibitors for the treatment of neurological disorders |
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2002
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2003
- 2003-07-08 DE DE60317675T patent/DE60317675T2/de not_active Expired - Lifetime
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- 2003-07-08 EA EA200500191A patent/EA007463B1/ru not_active IP Right Cessation
- 2003-07-08 CN CNB038166216A patent/CN100430058C/zh not_active Expired - Lifetime
- 2003-07-08 WO PCT/US2003/019548 patent/WO2004006928A1/en active IP Right Grant
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- 2003-07-08 KR KR1020057000501A patent/KR100687165B1/ko not_active IP Right Cessation
- 2003-07-09 TW TW092118725A patent/TWI315667B/zh not_active IP Right Cessation
- 2003-07-09 PE PE2003000687A patent/PE20040652A1/es not_active Application Discontinuation
- 2003-08-07 UA UA20041210897A patent/UA78801C2/uk unknown
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